Clinical Trials on Monogenic Diseases

Total 379288 results

Çağtay Maden

Completed

The Effects of Video Based Training and Aerobic Exercise Training in Individuals With Internet Gaming Disorder

Sedentary Behavior | Gaming Disorder

Turkey
Central South University

Unknown

Definitive Selection of Neuroimaging Biomarkers in Anxiety Disorder and Obsessive-compulsive Disorder: A Longitudinal Functional Magnetic Resonance Imaging （fMRI） Study With Paroxetine Treatment

Obsessive-Compulsive Disorder | Anxiety Disorder

China
Sunnybrook Health Sciences Centre

Unknown

Characterizing MyMood Patterns of Use

Depression | Mood Disorders | Bipolar Disorder | Dysthymia

Canada
Alexandria University

Unknown

Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1

Diagnoses, Syndromes, and Conditions | Sepsis Following A Procedure
Xijing Hospital
No. 102 Hospital of Chinese People's Liberation Army; The No.3 hospital of PLA and other collaborators

Completed

Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression

Depression

China
University of California, Los Angeles
American Foundation for Suicide Prevention

Completed

Mentalization-Based Therapy to Prevent Suicidal Behavior in Adolescents With Bipolar Disorder

Bipolar Disorder | Suicidal Ideation

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX

Major Depressive Disorder | Anxiety Disorder

United States
St. James's Hospital, Ireland
University of Dublin, Trinity College; Health Service Executive, Ireland; Royal...

Unknown

Mantra Meditation to Reduce Emotional Exhaustion in Emergency Department Staff

Psychological Stress

Ireland
Pfizer

Completed

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 to 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

Clostridium Difficile Associated Disease

United States
National Institute on Drug Abuse (NIDA)

Completed

Substance Dependent Teens - Impact of Treating Depression Study 1 - 1

Substance-Related Disorders | Alcohol-Related Disorders | Marijuana Abuse

United States
Africa Mental Health Foundation
University of British Columbia; Grand Challenges Canada; Nextgenu.org; CliniX Healthcare... and other collaborators

Completed

The Computer-based Drug and Alcohol Training Assessment in Kenya (eDATA K)

Substance-Related Disorders | Alcohol-Related Disorders | Social Stigma

Kenya
Centre for Addiction and Mental Health
National Institute of Mental Health (NIMH)

Completed

Preventing Depression Relapse With Mindfulness-Based Cognitive Therapy

Depression

Canada
H. Lundbeck A/S

Completed

Relapse-prevention Study With Lu AA21004 (Vortioxetine) in Patients With Generalized Anxiety Disorder

Generalized Anxiety Disorder

Chile, Argentina, Colombia, Costa Rica, Estonia, Finland, France, Hungary, Peru, Russian Federation, South Africa
Janssen-Cilag International NV

Completed

Prevention of Relapse With Injectable Paliperidone Palmitate Versus Oral Antipsychotics (PROSIPAL)

Schizophrenia

France, Ukraine, United Kingdom, Germany, Taiwan, Spain, Poland, Bulgaria, Romania, Russian Federation, South Africa, Greece, Israel, Korea, Republic of, Belgium, Estonia, Turkey, Czech Republic, Austria, Hungary, Lithuania, Slovakia and more
Örebro County Council
Uppsala University; Uppsala County Council, Sweden

Unknown

Internetbased Relapse Prevention for Partially Remitted Depression (ISAK)

Depression

Sweden
Academisch Medisch Centrum - Universiteit van Amsterdam...
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

Relapse Prevention in First Episode Schizophrenia: a 5 Year Trial

Schizophrenia

Netherlands
Duke University
National Institutes of Health (NIH)

Completed

Treatment of Mood and Marriage Study (TOMMS)

Major Depressive Disorder | Partner Relational Disorder (V61.10)

United States
AstraZeneca

Completed

A Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD) (Improve)

Major Depressive Disorder | MDD

Italy
GlaxoSmithKline

Completed

Patient Tolerability Study of GSK163090

Depressive Disorder, Major | Major Depressive Disorder (MDD)

United States
National Development and Research Institutes, Inc.
St. Luke's-Roosevelt Hospital Center

Unknown

Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders

Substance-Related Disorders | Alcohol-Related Disorders | Marijuana Abuse

United States
North Karelia Central Hospital
University of Kuopio Computing Center

Completed

Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty

Recurrent Inguinal Hernia

Finland
National Cancer Institute (NCI)
Celgene Corporation

Active, not recruiting

Rituximab, Lenalidomide, and Ibrutinib in Treating Patients With Previously Untreated Stage II-IV Follicular Lymphoma

Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma | Ann Arbor Stage II Grade 3 Non-Contiguous... and other conditions

United States
Arbeitsgemeinschaft medikamentoese Tumortherapie
Medical University of Graz

Terminated

Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck (AGMT_HNO_PN)

Locally Advanced Malignant Neoplasm | Squamous Cell Carcinoma of the Hypopharynx Stage III | Squamous Cell Carcinoma of the Hypopharynx Stage IV | Squamous Cell Carcinoma of the Oral Cavity Stage III | Squamous Cell Carcinoma of the Oral Cavity Stage IV | Laryngeal Squamous Cell Carcinoma Stage... and other conditions

Austria
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer Survivors (PACT)

Sedentary Lifestyle | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC... and other conditions

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage... and other conditions

United States
Walter Reed National Military Medical Center
National Intrepid Center of Excellence

Completed

Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress Symptoms (ArtTherapy)

Anger | PTSD | TBI (Traumatic Brain Injury) | Sleep Disturbance | Headache | Posttraumatic Stress Disorder | Combat Stress Disorders | Eating Disorders | Nightmare | Post-Traumatic Headache | TBI | Military Activity | Posttraumatic Stress Disorder, Delayed Onset | Irritable Mood | Combat and Operational Stress Reaction | Military Family and other conditions

United States
Suleyman Demirel University

Recruiting

Proprioception, Touch and Psychometric Relationship in Volleyball Players

Shoulder Injuries | Sports Physical Therapy | Somatosensory Disorders | Proprioceptive Disorders | Kinesiophobia

Turkey
Gruppo Oncologico Italiano di Ricerca Clinica

Recruiting

Durvalumab With Carboplatin and Etoposide Chemotherapy in Pulmonary Large-cell Neuroendocrine Carcinoma (LCNEC) (DUPLE)

Pulmonary Large-cell Neuroendocrine Carcinoma

Italy
Spark Biomedical, Inc.
Battelle Memorial Institute

Not yet recruiting

Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction (ASR)

Cognitive Performance | Acute Stress Reaction

United States
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Not yet recruiting

An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi

HIV/AIDS | Alcohol Abuse

Malawi
Chinese University of Hong Kong

Not yet recruiting

Digital Mood-enhanced CBT-I to Improve Depressive Symptoms in Adolescents

Adolescent | Depression | Insomnia

Hong Kong
Hunter College of City University of New York
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples (CHP)

HIV Infections | Substance Use

United States
Sultan Qaboos University

Not yet recruiting

Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized Trial

Depressive Disorder, Major
Ain Shams University

Recruiting

Comparison Between Bupivacaine-Dexmedetomidine Versus Bupivacaine-Dexamethasone in Pericapsular Nerve Group (PENG) Block

Hip Fractures | Post Operative Pain

Egypt
Stanford University

Not yet recruiting

Identification of Nerves Using Fluorescein Sodium

Head and Neck Disorder | Warthin Tumor | Pleomorphic Adenoma of the Parotid

United States
Melanoma and Skin Cancer Trials Limited
Monash University; The University of Queensland

Not yet recruiting

Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin) (SiroSkin)

Skin Cancer | Solid Organ Transplant Recipients

Australia
Massachusetts General Hospital
Boston University; University of Cape Town

Recruiting

South Africa Smoking Cessation and Engagement in HIV/TB Care Care

HIV Infections | Smoking Cessation | Tuberculosis

South Africa
Norwegian Center for Violence and Traumatic Stress...
King's College London; University of Oslo; Ministry of Health and Care Services...

Recruiting

Stepping Together for Children After Trauma, Norway (NorStep)

PTSD | Quality of Life | Sleep Disorder | Depressive Symptoms

Norway
Milton S. Hershey Medical Center

Recruiting

Pain and Disability Outcomes in Post Amputation Patients

Disability Physical | Limb Pain, Phantom | Residual Limbs Pain

United States
Dow University of Health Sciences

Recruiting

THE EFFICACY OF RESORBABLE PLATES VERSUS TITANIUM PLATES IN TERMS OF STABILITY IN MANDIBULAR FRACTURES.

Comparison of Resorbable Plates With Titanium Plates

Pakistan
Gazi University

Not yet recruiting

Admission of the Patient to the Clinic After Surgery

Post Operative Pain | Nurse's Role | Postoperative Hypothermia | Post-Op Hemorrhage
Beijing Tiantan Hospital
Peking University Third Hospital; Xuanwu Hospital, Beijing; Beijing Shijitan... and other collaborators

Not yet recruiting

Establishment and Clinical Application of Risk Classification Model Based on Molecular Typing of Medulloblastoma in Children

Medulloblastoma, Childhood
Women's Hospital School Of Medicine Zhejiang University

Not yet recruiting

Digital Cognitive Behavioral Therapy (dCBT-I) for Maternal Insomnia

Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
NYU Langone Health

Recruiting

Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder

Post Traumatic Stress Disorder

United States
University of California, Los Angeles
National Institute of Mental Health (NIMH)

Recruiting

Efficacy of Trigeminal Nerve Stimulation for ADHD

Attention-Deficit Hyperactivity Disorder

United States
Rutgers, The State University of New Jersey

Recruiting

Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control

Binge Drinking

United States
Dr. Ronnie Shapira

Not yet recruiting

Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma (MK3475-C01)

Metastatic Melanoma | Malignant Melanoma | Immunotherapy | Malignant Melanoma Stage IV | BRAF V600E
Lei Li
Beijing Qiyuanjuhe Biotechnology Co., Ltd

Recruiting

Host DNA Methylation for Endometrial Cancer Screening

Endometrial Cancer | Cohort Study | Liquid Biopsy | DNA Methylation | Cancer Screening | Cervical Cytology

China
Peking University People's Hospital

Not yet recruiting

the Effect of a New Type of Pelvic Floor Rehabilitation Device PHENIX U4+ on the Treatment of Urinary Incontinence

Urinary Incontinence

China
Drexel University
National Institute on Drug Abuse (NIDA)

Recruiting

Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs (TIARAS)

HIV Infections | Opioid Use | Trauma, Psychological

United States

Clinical Trials on Monogenic Diseases

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cameroon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations