Clinical Trials on Multiple Congenital Anomaly

Total 16259 results

Assistance Publique - Hôpitaux de Paris

Terminated

Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome (MARFANSARTAN)

Marfan Syndrome

France
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI); FDA Office of Orphan Products... and other collaborators

Completed

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network

Marfan Syndrome

United States, Canada, Belgium
Cardiff University

Completed

Comparison of Medical Therapies in Marfan Syndrome.

Marfan Syndrome

United Kingdom
National Taiwan University Hospital

Unknown

A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome (MFS)

Marfan Syndrome

Taiwan
Bayside Health
The Alfred; Baker Heart Research Institute

Completed

Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome

Marfan Syndrome
Quoin Pharmaceuticals

Recruiting

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome

United States
Sixera Pharma

Recruiting

A Study to Evaluate Topically Applied SXR1096 Cream in Patients With Netherton Syndrome

Netherton Syndrome

France
University Hospital, Toulouse
MedSharing

Recruiting

A Pilot Study of the Efficacy and Safety of Dupilumab Versus Placebo in Patients With Netherton Syndrome (NS-DUPI)

Netherton Syndrome

France
Children's Hospital of Philadelphia
Novartis Pharmaceuticals

Completed

Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome

Netherton Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Completed

Clinical Trial Using Humira in Netherton Syndrome (AntiTNF-SN)

Netherton Syndrome

France
University Hospital, Strasbourg, France

Recruiting

Description of Case of Infection With a New Species of Babesia and Its Molecular Diagnosis (BADIAG)

Babesiosis, Human

France
Azienda Ospedaliero-Universitaria di Modena

Recruiting

Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients With Turner Syndrome

Turner Syndrome | Anomaly Heart

Italy
Al-Azhar University

Completed

Needlescopic Inversion and Snaring of Hernia in Girls

Inguinal Hernia | Polyps | Fallopian Tube Injury | Round Ligament; Anomaly

Egypt
Azitra Inc.

Not yet recruiting

Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome

Netherton Syndrome

United States
Daiichi Sankyo

Recruiting

A Study to Explore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients With Netherton Syndrome

Netherton Syndrome

France
Boehringer Ingelheim

Not yet recruiting

Natural History of Netherton Syndrome

Netherton Syndrome
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, United States, Japan, France, Israel, Bulgaria, Italy, Switzerland, Netherlands, Portugal
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Gene Therapy for Netherton Syndrome

Netherton Syndrome

United Kingdom
Children's Healthcare of Atlanta
Emory University; Brigham and Women's Hospital; University of California, San... and other collaborators

Withdrawn

Genes Mutation Pentalogy of Cantrell

Pentalogy of Cantrell | Mutations in Non-muscle Genes

United States
IRCCS Policlinico S. Donato
University of Milan

Recruiting

Marfan Syndrome (MFS) and Facial Dysmorphism: Non-invasive 3D Assessment (FACE)

Marfan Syndrome | Rare Diseases

Italy
IRCCS Policlinico S. Donato

Recruiting

Transcriptomic Study of Adult Population With Marfan Syndrome (MaRfaNomicA)

Marfan Syndrome | Marfan's Syndrome With Cardiovascular Manifestations

Italy
Shriners Hospitals for Children
The University of Texas Health Science Center, Houston; Oregon Health and Science... and other collaborators

Unknown

Development of a Blood Test for Marfan Syndrome

Marfan Syndrome | Marfan Related Disorders | Control Subjects

United States
National Heart Centre Singapore

Unknown

Generation of Marfan Syndrome and Fontan Cardiovascular Models Using Patient-specific Induced Pluripotent Stem Cells

Marfan's Syndrome

Singapore
The University of Texas Health Science Center,...

Completed

Extended Criteria For Fetal Myelomeningocele Repair

Obesity | Pregnancy | Myelomeningocele | Diabetes Mellitus in Pregnancy | Fetal Anomaly

United States
Medical College of Wisconsin

Completed

Registry for Vascular Anomalies Associated With Coagulopathy (VAC)

Hemangiomas | Multifocal Lymphangioendotheliomatosis With Thrombocytopenia | Cutaneovisceral Angiomatosis With Thrombocytopenia | Vascular Anomaly With Thrombocytopenia

United States
Institut National de la Santé Et de la Recherche...

Unknown

Natural History and Biological Study of Netherton Syndrome (NSnatbio)

Healthy | Netherton Syndrome

France
Boston Children's Hospital
Litron Laboratories

Completed

Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data

Heterotaxy Syndrome

United States
Centre Hospitalier René Dubos

Completed

Retrospective Study of 110 Cases of Uterine Rupture to Determine Obstetric and Neonatal Complications (RUVO)

Anomaly Uterus
Dermelix Biotherapeutics, LLC.

Withdrawn

A Cross-Sectional Natural History Study to Evaluate Sweat Volume and Other Phenotypic and Genetic Characteristics in Patients Affected by XLHED

XLHED

United States
Fondation Ophtalmologique Adolphe de Rothschild
Institut National de la Santé Et de la Recherche Médicale, France

Terminated

Ability of a Molecule (Prima) to Restore Physiological Differentiation in Epithelium Expressing Gene p63 (PRIMAculture)

Ectodermal Dysplasia

France
Oregon Health and Science University

Terminated

Melatonin Levels in Smith Magenis Syndrome (SMS)

Chromosome Disorders

United States
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Not yet recruiting

Mortality and Morbidity Outcomes in Marfans

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations
Koç University
Wayne State University

Completed

Augmented Reality Exposure Therapy for Cynophobia

Phobia Animal

Turkey
Sohag University

Recruiting

Cryptosporidium Species in Sohag Governorate

Cryptosporidiosis

Egypt
Tufts University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Transmission and the Respiratory Tract in Cryptosporidiosis

Cryptosporidiosis

Uganda
Albireo

Active, not recruiting

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome (ASSERT-EXT)

Alagille Syndrome

United Kingdom, United States, France, Germany, Netherlands, Italy, Belgium, Malaysia, Poland, Turkey
University Hospital, Bordeaux
Fondation Syndrome de Rubinstein-Taybi

Completed

Rubinstein-Taybi Syndrome: Functional Imaging and Therapeutic Trial (RUBIVAL)

Rubinstein-Taybi Syndrome

France
National Human Genome Research Institute (NHGRI)

Completed

Clinical and Molecular Investigations Into Ciliopathies

Ciliopathy

United States
University Hospital, Bordeaux

Completed

Pathophysiology Analysis of "Costello Syndrome" on Cellular Models (COSTELLO)

Costello Syndrome

France
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Recruiting

Living With Marfans and Your Aorta: Surgical Outcomes Study (LIMA II)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom
Forteza, Albert, M.D.
Ministry of Health, Spain

Unknown

Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome (LO-AT-MARFAN01)

Marfan Syndrome

Spain
Children's Healthcare of Atlanta

Terminated

Prevalence and Clinical Spectrum of the 22q11 Deletion

Congenital Disorders

United States
Assistance Publique - Hôpitaux de Paris

Completed

Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease (MARFANLOMB)

Marfan Syndrome

France
IRCCS Policlinico S. Matteo
Merck Sharp & Dohme LLC; Menarini Group

Unknown

Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients (MaNeLo)

Marfan Syndrome

Italy
Karadeniz Technical University

Completed

Effects of Robotic Cat and Betta Fish Therapies in Hemodialysis Patients (Pet Therapy)

Hemodialysis | Loneliness | Happiness | Adaptation | Animal Assisted Therapy | Symptom

Turkey
Mirum Pharmaceuticals, Inc.

Recruiting

Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP) (LEAP)

Alagille Syndrome

United States
Albireo

Completed

Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome (ASSERT)

Alagille Syndrome

United States, United Kingdom, France, Germany, Canada, Netherlands, Italy, Malaysia, Belgium, Israel, New Zealand, Poland, Turkey
National Human Genome Research Institute (NHGRI)

Completed

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Alagille Syndrome

United States
60 Degrees Pharmaceuticals LLC

Not yet recruiting

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

Babesiosis
Hoffmann-La Roche

Completed

A Study To Assess Distribution Of RO7248824 In The Central Nervous System Following Single Intrathecal Doses Of [89zr] Labeled RO7248824 In Healthy Male Participants

Angelman Syndrome

Netherlands

Clinical Trials on Multiple Congenital Anomaly

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Tanzania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations