Clinical Trials on Musculoskeletal Pain

Total 48743 results

University of Washington
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

DePTH: De-emphasize PTH

Kidney Failure, Chronic | Chronic Kidney Disease-Mineral and Bone Disorder

United States
Rigel Pharmaceuticals
Nationwide Children's Hospital

Not yet recruiting

Study of Olutasidenib and Temozolomide in HGG

Astrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditions

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Inozyme Pharma

Recruiting

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/Phosphodiesterase1 Deficiency

United States, United Kingdom, Canada
Amgen

Recruiting

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Behçet's Disease

Spain, Turkey, Israel, Greece
VA Office of Research and Development

Not yet recruiting

iBCI Optimization for Veterans With Paralysis

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injury | Brain Stem Infarctions | Locked-in Syndrome

United States
Maastricht University Medical Center
Sun Pharmaceutical Industries Limited

Recruiting

Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study

Carcinoma | Carcinoma, Basal Cell | Skin Cancer | Basal Cell Nevus Syndrome | Neoplasms, Basal Cell | Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma | Gorlin Syndrome | Basal Cell Tumor | Neoplasm of Skin

Netherlands
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
University Hospital, Clermont-Ferrand
I-SITE Cap 20-25 project

Recruiting

Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort (EVALMOB)

Parkinson Disease | Joint Osteoarthritis | Atherosclerosis of the Distal Arteries, Without Gangrene | Chronic Obstructive Pulmonary Disease, Unspecified | Obesity, Unspecified

France
University of Texas Southwestern Medical Center

Recruiting

UTSW HP [13-C] Pyruvate Injection in HCM (HPHCM)

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dilated Cardiomyopathy | Cardiomyopathy, Hypertrophic | Heart Failure With Reduced Ejection Fraction | Cardiac Sarcoidosis | Heart Failure With Preserved Ejection Fraction

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); Boehringer Ingelheim; Cystic...

Recruiting

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

Smoking | Smoking Cessation | Chronic Obstructive Pulmonary Disease (COPD) | Idiopathic Pulmonary Fibrosis (IPF) | Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD) | Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)

United States
LG Chem

Recruiting

Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children (LGS)

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

Korea, Republic of
Chinook Therapeutics U.S., Inc.

Active, not recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases (AFFINITY)

Diabetic Kidney Disease | Focal Segmental Glomerulosclerosis | Immunoglobulin A Nephropathy | IgA Nephropathy | Diabetic Nephropathy Type 2 | Alport Syndrome

United States, Spain, Korea, Republic of, Australia, Italy, United Kingdom
Beth Israel Deaconess Medical Center

Completed

Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders (QUESST)

Stroke | Parkinson's Disease | Myasthenia Gravis | Amyotrophic Lateral Sclerosis (ALS) | Myopathies

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE) (EAGLE)

Chronic Kidney Diseases | Autosomal Dominant Polycystic Kidney | Alport Syndrome

United States, France, Australia, Japan, Spain, Puerto Rico
University Hospital, Gentofte, Copenhagen

Active, not recruiting

The Relationship Between Inflammatory ARTritis and CArdiac DIseAse (ARTCADIA)

Myocardial Infarction | Heart Failure | Stroke | Rheumatoid Arthritis | Ischemic Heart Disease | Inflammatory Arthritis | Heart Failure, Diastolic | Valvular Heart Disease | Heart Failure, Systolic | Spondylitis, Ankylosing | Cardiac Disease | Spondyloarthritis | Axial Spondyloarthritis | Myocardial Dysfunction | Left...

Denmark
University of Utah

Completed

Hypovitaminosis D in Neurocritical Patients

Stroke | Critical Illness | Craniocerebral Trauma | Brain Neoplasms | Seizures | Meningitis | Intracranial Hemorrhages | Spinal Cord Injuries | Intracranial Aneurysm | Vitamin d Deficiency

United States
QuantalX Neuroscience

Completed

Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.

Healthy | Hemorrhage | Cognitive Impairment | Dementia | Fibromyalgia | TBI (Traumatic Brain Injury) | Cognitive Decline | Concussion, Brain | MS (Multiple Sclerosis) | Adhd | CVA | ABD | Mci

Israel
University of Sao Paulo General Hospital

Withdrawn

Cholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney Disease (RLS)

Vitamin D Deficiency | Hyperparathyroidism, Secondary | Renal Disease, End Stage | Adynamic Bone Disease | Restless Leg Disorder | Renal Disease Bone

Brazil
University of Southern Denmark
Odense University Hospital; Aarhus University Hospital; University of Copenhagen and other collaborators

Completed

Chronic Inflammatory Disease, Lifestyle and Treatment Response (BELIEVE)

Autoimmune Diseases | Inflammatory Bowel Diseases | Uveitis | Psoriasis | Spondylarthropathies | Crohn Disease (CD) | Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Hidradenitis Suppurativa (HS) | Colitis, Ulcerative (UC)

Denmark
Alpine Immune Sciences, Inc.

Completed

Cell Surface Marker Expression in Autoimmune Diseases (CASCADE)

Multiple Sclerosis | Systemic Lupus Erythematosus | Systemic Sclerosis | Crohn's Disease | Ulcerative Colitis | Sjogren's Syndrome | Inflammatory Myositis

Canada
Merck KGaA, Darmstadt, Germany

Completed

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Growth Hormone Deficiency | Turner Syndrome

Argentina, Australia, Austria, Canada, France, Germany, Italy, Norway, Russian Federation, Singapore, Spain, Sweden, United Kingdom
University of Zurich
University Children's Hospital, Zurich; Ehlers-Danlos Network, Switzerland

Completed

Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome

Obstructive Sleep Apnea | Ehler's Danlos Syndrome

Switzerland
University of Zurich
University Children's Hospital, Zurich; Ehlers-Danlos Network, Switzerland

Completed

Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome (OSA in EDS)

Obstructive Sleep Apnea | Ehlers-Danlos Syndrome

Switzerland
National Cancer Institute (NCI)

Completed

Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma | Retinoblastoma

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
UMC Utrecht
Dutch Health Care Insurance Board

Completed

Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.

Rheumatoid Arthritis | Polymyositis | Giant Cell Arteritis | Polymyalgia Rheumatica | Wegener's Granulomatosis

Netherlands
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
University of Edinburgh

Recruiting

Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition (CHIEFTain)

Myocarditis | Hypertrophic Cardiomyopathy | Cardiac Sarcoidosis | Heart Failure With Preserved Ejection Fraction | Hypertensive Heart Disease | Arrhythmogenic Right Ventricular Cardiomyopathy 1 | Tako Tsubo Cardiomyopathy

United Kingdom
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
Thomas Nickolas, MD MS
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Indiana...

Recruiting

Precision Medicine Approaches to Renal Osteodystrophy (PMaROD)

Chronic Kidney Diseases | Secondary Hyperparathyroidism | Renal Osteodystrophy | Bone Turnover Rate Disorder | CKD-MBD

United States
University of California, San Diego
New York University; Heinrich-Heine University, Duesseldorf; Universität Tübingen

Recruiting

Natural History Study of Patients With HPDL Mutations

Genetic Disease | Mitochondrial Encephalomyopathies | Neonatal Encephalopathy | Mutation | Hereditary Spastic Paraplegia | White Matter Disease | Spastic Paraplegia

United States
Inozyme Pharma

Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency (ENERGY)

Generalized Arterial Calcification of Infancy | Autosomal Recessive Hypophosphatemic Rickets | Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency

United States, United Kingdom
University of Nebraska

Recruiting

ADX-629 Therapy for Sjogren-Larsson Syndrome

Sjogren-Larsson Syndrome

United States
Western University, Canada
Western University; The Kidney Foundation of Canada; Academic Medical Organization... and other collaborators

Recruiting

PRevEnting FracturEs in REnal Disease 1 (PREFERRED-1)

Kidney Diseases | Chronic Kidney Disease-Mineral and Bone Disorder | Fragility Fracture | Dialysis; Complications

Canada
National Medical Research Center for Rehabilitation...
Pirogov Russian National Research Medical University; DNKOM LLC; The Orenburg...

Recruiting

Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old

Cardiovascular Diseases | Nervous System Diseases | Urologic Diseases | Diabetes | Neuromuscular Diseases | Hypercholesterolemia | Gout | Hyperbilirubinemia | Hyper IgE Syndrome | Hyper-LDL-cholesterolemia | Hyper Beta Lipoproteinemia | Hyper Eosinophilic Syndrome

Russian Federation
Aldeyra Therapeutics, Inc.

Completed

RESET Trial - Part 1 - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS)

Sjogren-Larsson Syndrome

United States
University Hospital, Clermont-Ferrand

Completed

Towards the Use of Instrumented Tests for Screening the Risk of Falling in Patients With Chronic Illness. (DETECACTI)

Parkinson Disease | Joint Osteoarthritis | Atherosclerosis of the Distal Arteries, Without Gangrene | Chronic Obstructive Pulmonary Disease, Unspecified | Obesity, Unspecified

France
Salome Kristensen

Terminated

COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Psoriatic Arthritis | Axial Spondyloarthritis

Denmark
University of South Florida
University of Miami; National Institutes of Health (NIH); University of Kansas

Completed

A Patient Centric Motor Neuron Disease Activities of Daily Living Scale

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | Hereditary Spastic Paraplegia
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
Ain Shams University

Unknown

National Registry for Egyptian Pediatric Neuromuscular Diseases

Muscular Dystrophy | Polyneuropathies | Spinal Muscular Atrophy | Muscle Diseases | Myasthenic Syndromes

Egypt
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer

Sarcoma | Kidney Cancer

United States
Shaare Zedek Medical Center

Completed

Procalcitonin Level and Kinetics in Children With Bacterial Infections

Bacterial Infections | Bacteremia | Cellulitis | Urinary Tract Infection | Meningitis | Osteomyelitis | Septic Arthritis | Mastoiditis | Lobar Pneumonia

Israel
King's College London

Recruiting

The Living With a Long-Term Condition Study (LTC)

Liver Diseases | Heart Diseases | Heart Failure | Stroke | Cerebrovascular Disorders | Epilepsy | Pain | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Migraine | Hepatitis | Atrial Fibrillation | Asthma | Endometriosis | Dementia | Fibromyalgia | Celiac... and other conditions

United Kingdom
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Prevention of Weight Gain in Early Psychoses

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Major Depressive Disorder | Bipolar I Disorder | Bipolar II Disorder | Psychosis Not Otherwise Specified | Substance-Induced Psychoses

Canada
Microclinic International
Royal Health Awareness Society (RHAS); Jordanian Ministry of Health (MoH)

Completed

Microclinic Social Network Behavioral Health Trial in Jordan

Hyperglycemia | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Body Weight | Weight Loss | Blood Pressure | Weight Gain | Social Behavior | Weight, Body | Glucose, High Blood | Lifestyle, Healthy | Weight Change, Body | Behavior, Health | Lifestyle Risk Reduction | Blood Pressure, High | Hyperglycaemia... and other conditions

Jordan
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
Motric Bio

Recruiting

Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals

Stroke | Multiple Sclerosis | Cerebral Palsy | Spinal Cord Injuries | Dystonia | Muscle Spasticity | Hereditary Spastic Paraplegia | Hypertonia, Muscle

United States
Brigham and Women's Hospital
Bristol-Myers Squibb

Recruiting

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity (RAISE)

Rheumatoid Arthritis | Systemic Sclerosis | Inflammatory Arthritis | Psoriatic Arthritis | Sjogren's Syndrome | Juvenile Rheumatoid Arthritis | Ankylosing Spondylitis | Undifferentiated Connective Tissue Diseases | Lupus | Sacroiliitis | Sicca Syndrome | Mixed Connective Tissue Disease | Palindromic Arthritis | Enteropathic...

United States
LMU Klinikum

Recruiting

Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease

Pompe Disease (Late-onset) | FSHD | Spinal Muscular Atrophy Type 3 | Inclusion Body Myositis

Germany

Clinical Trials on Musculoskeletal Pain

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