Clinical Trials on Mutation Abnormality
Total 1917 results
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Verastem, Inc.RecruitingMetastatic Cancer | Pancreas Cancer | Neoplasms Pancreatic | KRAS Activating Mutation | Malignant Neoplasm of PancreasUnited States
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Prelude TherapeuticsRecruitingAdvanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancers | SMARCA4 Gene MutationUnited States, France, Spain, Singapore, Netherlands
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Shanghai Chest HospitalRecruitingMetastatic Cancer | Adenocarcinoma of Lung | Non-Small Cell Lung Cancer With EGFR Mutation | Locally Advanced Solid TumorChina
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Universitaire Ziekenhuizen KU LeuvenRecruitingNon-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor ReceptorBelgium
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University of UtahActive, not recruitingNon-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor (Disorder)United States
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AstraZenecaParexelCompletedEGFR Mutation Positive Locally Advanced or Metastatic Non-Small Cell Lung CancerSpain, United States, Italy, Korea, Republic of, Malaysia
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Vertex Pharmaceuticals IncorporatedCompletedCystic Fibrosis, Homozygous or Heterozygous for the F508del-CFTR MutationUnited States, France, United Kingdom, Germany, Spain, Belgium, Canada, Australia, Netherlands, Denmark, Czech Republic, Italy, Austria, Ireland, Sweden
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Spaulding Rehabilitation HospitalEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsNot yet recruitingAmputation | Diabete Type 2United States
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Arog Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior TherapiesUnited States
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Gaziosmanpasa Research and Education HospitalCompletedPostoperative Pain | Analgesia | Cholecystectomy | Postoperative Pain Management | Nerve Blocks | Nerve Block DurationTurkey
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University of California, BerkeleyTerminatedSuicidal Ideation | Impulsivity | Deliberate Self-harmUnited States
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University Hospital, LimogesTerminatedExtended Ileal Resection Under Laparotomy | Total Proctocolectomy Under Laparotomy | Colectomy Left/Right/Total Under Laparotomy | Rectosigmoidal Resection Under Laparotomy | Anterior Resection of Rectum Under Laparotomy | Abdomino-perineal Amputation Under LaparotomyFrance
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Rigshospitalet, DenmarkUnknownSleep Duration on the First Night After SurgeryDenmark
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University Hospital, BordeauxTerminated
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Regeneron PharmaceuticalsRecruitingCongenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)Spain, United Kingdom, United States
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Assistance Publique - Hôpitaux de ParisInstitut National de la Santé Et de la Recherche Médicale, France; ANSESNot yet recruitingEnvironmental Exposure | Genetic Predisposition | SDH Gene Mutation
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Kymera Therapeutics, Inc.SuspendedNon Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | DLBCL | MYD88 Gene MutationUnited States, United Kingdom
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Balikesir UniversityCompletedAnxiety | Labor Pain | Duration of Labor | Labor ComfortTurkey
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The University of Hong KongNorth District Hospital; Queen Mary Hospital, Hong Kong; Pamela Youde Nethersole... and other collaboratorsUnknownSelf Inflicted Injury | Suicide and Self Inflicted InjuryHong Kong
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National Cancer Institute (NCI)RecruitingNeoplasms | Li-Fraumeni Syndrome | Tp53 MutationsUnited States
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Yonsei UniversityUnknownCompletely Resected NSCLC With Common EGFR MutationsKorea, Republic of
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Scripps HealthRecruitingSleep | Sleep Fragmentation | White Noise | Sleep DurationUnited States
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Hull University Teaching Hospitals NHS TrustUniversity of HullCompletedWound Infection | Amputation WoundUnited Kingdom
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American University of Beirut Medical CenterCompletedPharmacogenetic and Duration of Labor Fentanyl AnalgesiaLebanon
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Nantes University HospitalCompletedPrimary Raynaud's Phenomenon (PR) | Genetic Mutations Causing PR | Study of Patients and Their Relatives (With or Without Primary PR)France
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Daping Hospital and the Research Institute of Surgery...Not yet recruitingNon-Small Cell Lung Cancer Without Mutation in Epidermal Growth Factor Receptor (Disorder)
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Pierre Fabre MedicamentIqvia Pty LtdRecruitingBRAF V600 Mutation | Metastatic Non-small Cell Lung CancerFrance
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Stealth BioTherapeutics Inc.Active, not recruitingMitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism DefectSpain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
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Intergroupe Francophone de Cancerologie ThoraciqueNovartisCompletedNon Small Cell Lung Cancer | BRAF V600 MutationFrance
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AstraZenecaCompletedEGFR Mutation Positive Advanced Non Small Cell Lung CancerUnited States, Korea, Republic of, Taiwan, Australia
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Nanfang Hospital, Southern Medical UniversityRecruitingAcute Lymphoblastic Leukemia | Philadelphia Chromosome | Adult ALL | Philadelphia-Positive ALL | IKZF1 Gene MutationChina
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British Columbia Cancer AgencyRecruitingNon Small Cell Lung Cancer | EGFR Activating Mutation | Leptomeningeal MetastasisCanada
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); GlaxoSmithKline; Genentech, Inc.; Brain Science...RecruitingIntracranial Meningioma | Recurrent Meningioma | NF2 Gene MutationUnited States
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SwanBio Therapeutics, Inc.Active, not recruitingAMN | AMN Gene Mutation | X-ALDUnited States, Netherlands, Germany
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Henan Provincial People's HospitalCompletedHypertrophic Cardiomyopathy | Prognosis | Genetic Mutation | Coronary Artery Anomaly | Myocardial DeformationChina
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Peking Union Medical College HospitalOrigiMedRecruitingQuality of Life | Objective Response Rate | Overall Survival | Progression-free Survival | Disease Control Rate | Duration of Response | Five-year Survival RateChina
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National Institute of Nursing Research (NINR)WithdrawnPain | Amputation | Polymorphism-Genetic
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University of OttawaCompletedBorderline Personality Disorder | Deliberate Self Harm
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Federal University of ParaíbaRecruitingParkinson Disease | Cognition Disorder | EEG With Abnormally Slow FrequenciesBrazil
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University of LeicesterRecruitingAmputation | Physical Disability | Vascular Disease, PeripheralUnited Kingdom
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Centro di Riferimento Oncologico - AvianoRecruitingNon Small Cell Lung Cancer Metastatic | ALK Gene MutationItaly
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Hunan Province Tumor HospitalRecruitingNon Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | RET Gene Mutation | MET AmplificationChina
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Instituto Nacional de Cancerologia de MexicoRecruitingNon-Small Cell Lung Cancer With EGFR MutationMexico
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Centre Leon BerardRecruitingCancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditionsFrance, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
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Fudan UniversityRecruitingDiffuse Large B Cell Lymphoma, Gene MutationChina
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Xiuning LeM.D. Anderson Cancer Center; Eli Lilly and CompanyActive, not recruitingNon Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | EGFR Gene MutationUnited States
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Turning Point Therapeutics, Inc.TerminatedNon-Small Cell Lung Cancer | NSCLC | Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | ALK Gene MutationUnited States, Australia, Korea, Republic of
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Escape Bio, Inc.Momentum Pharma; Science 37TerminatedPatients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) GeneUnited States
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Rabin Medical CenterCompletedDesmoid Fibromatosis | Desmoid | Desmoid Fibromatosis of Skin | Desmoid Neoplasm of Chest Wall | Desmoid Tumor Caused by Somatic Mutation | Aggressive Fibromatoses | Fibromatosis DesmoidIsrael
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University Hospital, BordeauxCompletedMutation | Oculocutaneous Albinism