Clinical Trials on Mycobacterium Avium Complex Infections

Total 1990 results

University of Oxford

Completed

A Study to Determine the Safety and Immunogenicity of a Candidate MAP Vaccines ChAdOx2 HAV and MVA in Healthy Adult Volunteers

Crohn Disease | Mycobacterium Avium Subspecies Paratuberculosis

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...
Abbott

Completed

A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Treatment for Mycobacterium Avium Complex (MAC) on the Cells of HIV-Infected Patients

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Aaron Diamond AIDS Research Center

Completed

Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
Pfizer

Completed

A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
InterMune

Terminated

Safety and Efficacy of Inhaled Interferon Gamma-1b in Pulmonary MAC Infection

Lung Infection
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Taiwan University Hospital

Completed

Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease

Mycobacterium Avium

Taiwan
National Institute of Allergy and Infectious Diseases...

Completed

Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048

HIV Infections | Pneumococcal Infections | Mycobacterium Avium-intracellulare Infection

United States
National Taiwan University Hospital

Unknown

The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease

To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage | To Compare the Difference of Inflammasome Response of Inflammatory Macrophage | To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response

Taiwan
National Institute of Allergy and Infectious Diseases...

Completed

Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Medstar Health Research Institute

Withdrawn

Treatment of Crohn's Disease With an Antibiotic Regimen Directed Against Mycobacterium Avium Paratuberculosis

Crohn's Disease
Pfizer

Completed

An Open, Multicenter, Randomized, Dose-Ranging Study of Azithromycin in the Treatment of Disseminated Mycobacterium Avium-Intracellulare Complex Infection (MAC) in Patients With Acquired Immune Deficiency Syndrome (AIDS)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
University of Illinois at Chicago

Terminated

Treatment Outcomes in Patient With Nontuberculous Mycobacterial Disease

Atypical Mycobacterium Infections | Nontuberculous Mycobacterial Disease

United States
University of British Columbia
Mallinckrodt

Completed

Prolonged-Use of Inhaled Gaseous Nitric Oxide (gNO) for Adult With Non-Tuberculous Mycobacteria Infection

Non-Tuberculous Mycobacterial Pneumonia

Canada
Paratek Pharmaceuticals Inc

Active, not recruiting

Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)

Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection

United States
Kwong Wah Hospital
The Hong Kong Society of Nephrology

Unknown

Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis

Rate of Exit Site Infection | Rate of Atypical Mycobacterial Infection | Rate of Peritoneal Dialysis

Hong Kong
Mahidol University
Siam Pharmaceutical Ltd.

Unknown

Linezolid for Treatment of Nontuberculous Mycobacterial Diseases

Non-tuberculous Mycobacterial Infections

Thailand
Medical University of South Carolina
Oregon Health and Science University; Cystic Fibrosis Foundation

Completed

A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection

Nontuberculous Mycobacterium Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Sildenafil for PNTM Infection

Nontuberculous Mycobacterial Infection

United States
National Jewish Health

Recruiting

Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt) (C)

Mycobacterium Infections | Healthcare Associated Infection | Nontuberculous Mycobacterial Pulmonary Infection | Outbreak Investigation

United States
Samsung Medical Center

Terminated

Rapid Identification of Mycobacteria in Acid-fast Bacilli Smear-positive Respiratory Specimens

Mycobacterium Infections | Atypical Mycobacteria

Korea, Republic of
University Hospital, Strasbourg, France

Recruiting

State of Play of Non-tuberculous Mycobacteria in Alsace (Mycoba)

Non-Tuberculous Mycobacteria

France
Oregon Health and Science University
University Health Network, Toronto; New York University; NTM Info & Research,...

Recruiting

Hypertonic Saline for MAC

Nontuberculous Mycobacterial Lung Disease | Nontuberculous Mycobacterium Infection

United States, Canada
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma

Opportunistic Infections | Mycobacterium Tuberculosis | Nontuberculous Mycobacteria

Thailand, China, Taiwan
King Chulalongkorn Memorial Hospital

Completed

Treatment Outcome Between Mycobacterium Abscessus Infection in Chronic Lung Disease and Acquired Interferon-gamma Autoantibody Syndrome

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterial Pulmonary Infection | Adult-Onset Immunodeficiency With Acquired Anti-Interferon-Gamma Autoantibodies

Thailand
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; IRCCS Azienda... and other collaborators

Recruiting

The Italian REgistry of Pulmonary Non-tuberculous mycobactEria (IRENE)

Nontuberculous Mycobacteria

Italy
St George's, University of London

Unknown

Innovative Reagents for Improving Rapid Diagnosis of Mycobacterial Infections (TIKA_TB)

Tuberculosis (TB)

United Kingdom
National Institutes of Health Clinical Center (CC)

Completed

Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

Mycobacterium Infections, Non-tuberculous

United States
Radboud University Medical Center

Completed

PK and PD of Drugs for Nontuberculous Mycobacterial Diseases in Dutch Patients (NTM)

Nontuberculous Mycobacterial Diseases

Netherlands
Radboud University Medical Center

Completed

Pharmacokinetic Study With a Loading Dose of Clofazimine in Adult Patients With Nontuberculous Mycobacterial Disease (C-LOAD)

Nontuberculous Mycobacterial Diseases

Netherlands
University Hospital, Geneva

Completed

An Ecological Analysis of Nontuberculous Mycobacteria in the Geneva Area (2015-2020)

Ecology of Nontubercuous Mycobacteria | Geneva Area

Switzerland
Seoul National University Hospital

Not yet recruiting

PK and PD of Antibiotics for Treatment of Mycobacterium Abscessus Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Infection
Western University of Health Sciences

Completed

Topical Absorption of Glutathione-cyclodextrin Complex in Healthy Human Subjects Improves Immune Response Against Mycobacterium Infection

Glutathione-cyclodextrin Complex Absorption

United States
The University of Texas Health Science Center at...
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Tigecycline for Treatment of Rapidly Growing Mycobacteria

Mycobacterium Abscessus Lung Disease | Rapidly Growing Mycobacterial Lung Disease

United States
LigaChem Biosciences, Inc.

Active, not recruiting

Study to Evaluate the Efficacy of Delpazolid as Add-on Therapy in Refractory Mycobacterium Abscessus Complex

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterium Infection

Korea, Republic of
Chinese University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong

Completed

Multiplex PCR -Microarray-based Assay in the Detection of Mycobacterium

Tuberculosis | Non-Tuberculous Mycobacterial Pneumonia

Hong Kong
Kevin Winthrop
The University of Texas Health Science Center at Tyler; Insmed Incorporated

Completed

Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease

Mycobacterium Infections, Nontuberculous | Mycobacteria, Atypical

United States
Pfizer

Completed

Safety And Efficacy Of Rifabutin In Patients For Non-HIV Patients

Tuberculosis | Non-tuberculous Mycobacterial Diseases (Including MAC Disease)
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Rapid and Accurate Detection of Major Mycobacterium Species in Pulmonary Infection Based on GenSeizer Platform

Mycobacterium Pulmonary Infection

China
National Jewish Health
Cystic Fibrosis Foundation

Enrolling by invitation

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria (POSTSTAMP)

Mycobacterium Infections | Cystic Fibrosis | Nontuberculous Mycobacterial Lung Disease | Nontuberculous Mycobacterium Infection | Mycobacterium; Pulmonary

United States
Yonsei University

Recruiting

Exercise Intervention in Patients With Nontuberculous Mycobacterial Pulmonary Disease

Nontuberculous Mycobacteria

Korea, Republic of
Inje University
Ministry of Science and ICT

Recruiting

Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB)

Latent Tuberculosis | Tuberculosis | Nontuberculous Mycobacterium Infection

Korea, Republic of, Indonesia
The University of Queensland
University of Copenhagen; Erasmus Medical Center; Monash University; Hôpital Cochin and other collaborators

Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT)

Pulmonary Disease Due to Mycobacteria (Diagnosis)

Australia, Canada, Denmark, France, Ireland, Netherlands, New Zealand, United Kingdom, Singapore
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru

Clinical Trials on Mycobacterium Avium Complex Infections

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ethiopia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations