Clinical Trials on NGLY1 Deficiency in United Kingdom

Total 4510 results

NHS Tayside
University of Dundee

Completed

Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone (RAMP)

Ataxia-Telangiectasia

United Kingdom
Applied Therapeutics, Inc.

Active, not recruiting

Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency (INSPIRE)

Hereditary Neuropathy Caused by SORD Deficiency

United States, United Kingdom, Czechia, Italy
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain, United States, United Kingdom
Northumbria University
Bayer

Completed

Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being

Cognitive Function and Mood | Non-anaemic Iron Deficiency

United Kingdom
Grifols Therapeutics LLC

Completed

Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)

Alpha 1-Antitrypsin Deficiency

Denmark, Sweden, United Kingdom
ViiV Healthcare

Completed

A Study to Compare the Relative Bioavailability of Two Different Formulations of GSK3640254

HIV Infections

United Kingdom
Medicines Development for Global Health
Imperial College London; Phillip T. and Susan M. Ragon Foundation

Terminated

A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People

HIV Infections

United Kingdom
St Stephens Aids Trust

Terminated

Impact of Maraviroc on the Immune Function in HIV-1 Infected Subjects Receiving Immunisation With Novel Antigens

HIV Infections

United Kingdom
Gilead Sciences

Completed

Metabolic Impact Assessment of Tenofovir Disoproxil Fumarate on Non-HIV-1 Infected Healthy Adult Male Volunteers

HIV Infections

United Kingdom
University of Sussex
Brighton and Sussex University Hospitals NHS Trust

Active, not recruiting

Patients' Experiences and Perceptions of 3TC/DTG Dual Therapy (the PEDAL Study) (PEDAL)

HIV Infections

United Kingdom
ViiV Healthcare

Completed

Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254

HIV Infections

United Kingdom
ViiV Healthcare

Completed

Dolutegravir Pediatric Liquid Formulation Study

HIV Infections

United Kingdom
Imperial College London
Pfizer

Completed

The Maraviroc Central Nervous System (CNS) Study

HIV Infections

United Kingdom
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine

HIV Infections

United Kingdom
Gilead Sciences

Completed

ONCE - Only Nocturnal Combination Evaluation of Antiretroviral-Experienced HIV 1 Infected Subjects Switching to Atripla (ONCE)

HIV Infections

United Kingdom
Royal Free Hampstead NHS Trust
Roche Pharma AG

Completed

Lopinavir Capsules to Kaletra or Invirase Tablets (LoCKIT)

HIV Infections

United Kingdom
Imperial College London
Wellcome Trust; National Institute for Health Research, United Kingdom

Completed

The Safety and Immunogenicity of a Potential HIV Vaccine

HIV Infections

United Kingdom
Imperial College London

Completed

The Raltegravir and Ribavirin Pharmacokinetics (PK) Study

HIV Infections

United Kingdom
University College, London
King's College London

Unknown

Regional Bone Turnover Using 18F-fluoride-PET/CT in HIV-1-infected Men: PETRAM Study (PETRAM)

HIV Infections

United Kingdom
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients

HIV Infections

United Kingdom
Kirby Institute

Completed

Pharmacokinetics of Lamivudine at Two Different Doses (ENCORE2)

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Double Protease Inhibitor to Darunavir Switch Study

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Maraviroc 300 mg Twice Daily in HIV Negative Male Volunteers

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects

HIV Infections

United Kingdom
St Stephens Aids Trust

Completed

TMC 125 Blood Levels Study

HIV Infections

United Kingdom
Royal Centre for Defence Medicine
Liverpool John Moores University; Leeds Beckett University

Unknown

Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion (IMPACTCOVID)

Covid19 | Vitamin D Deficiency | SARS-CoV Infection | Acute Respiratory Tract Infection

United Kingdom
Arrowhead Pharmaceuticals

Terminated

A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Alpha-1 Antitrypsin Deficiency

Australia, Netherlands, Germany, United Kingdom
Imperial College London

Withdrawn

Determining the Reproductive Health of Men Post-COVID-19 Infection

Infertility, Male | Testosterone Deficiency

United Kingdom
St Stephens Aids Trust

Completed

The Pharmacology/Aging Clinic (SSAT041)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Atripla to Raltegravir Switch Study for CNS Toxicity (SSAT036)

HIV Infection

United Kingdom
St Stephens Aids Trust

Unknown

Hydroxychloroquine for Discordant CD4 Responders on Highly Active Antiretroviral Therapy (HAART) (SSAT039)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

PK Switch Efavirenz to Maraviroc in Patients Initially Suppressed on an Efavirenz-containing Regimen (SSAT033)

HIV Infection

United Kingdom
Barts & The London NHS Trust

Completed

Lymphocyte Immunophenotyping in Common Variable Immunodeficiency

Bronchiectasis | Common Variable Immunodeficiency | Granulomatous Disease | Immunoglobulin Treatment

United Kingdom
St Stephens Aids Trust

Completed

Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA.

HIV Infection

United Kingdom
Imperial College London

Terminated

The First Failure Study (FAST)

HIV Infections | HIV

United Kingdom
St Stephens Aids Trust

Withdrawn

Depot Contraception With and Without Lopinavir/Ritonavir

HIV Infection

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Time to Protection and Adherence Requirements of Raltegravir With or Without Lamivudine in Protection From HIV Infection (R-PrEP)

Hiv

United Kingdom
St George's, University of London

Unknown

Study of Single IV Administration of P2G12 (FuturePharma)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Atazanavir/Ritonavir and Zinc Pharmacokinetic Study (SSAT043)

HIV Infection

United Kingdom
St Stephens Aids Trust

Completed

Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study

HIV Infections | HIV

United Kingdom
GlaxoSmithKline

Completed

Comparison of Abacavir Following Once-Daily And Twice-Daily Administration In HIV Infected Subjects

HIV Infection

United Kingdom
Arcturus Therapeutics, Inc.

Recruiting

Study for Adolescent and Adult Participants With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810

OTC Deficiency | Ornithine Transcarbamylase Deficiency | OTCD

Spain, Belgium, United Kingdom, Sweden
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; Royal Papworth Hospital

Active, not recruiting

A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia (N-HAT)

Ataxia Telangiectasia

United Kingdom
Texas A&M University

Unknown

Nutrition, Vision, and Cognition in Sport Study: Beef (IONSport:Beef)

Cognitive Change | Nutritional Anemia | Diet, Healthy | Nutrient Deficiency | Diet; Deficiency | Visual Spatial Processing | Dietary Deficiency | Dietary B12 Deficiency | Dietary Zinc Deficiency | Dietary Vitamin B12 Deficiency Anemia | Dietary Deficiency of Selenium and Vitamin E

United States
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Improving Phosphate Control in Children With CKD (IMPACT)

Chronic Kidney Diseases | Hyperphosphatemia | Chronic Kidney Disease-Mineral and Bone Disorder | Pediatric Kidney Disease | CKD-MBD

United Kingdom
Imperial College London
Boehringer Ingelheim

Completed

The CogNaive Study: Assessing Changes in Neurocognitive Function in Treatment Naïve HIV-1 Positive Subjects

HIV Infections

United Kingdom
St George's, University of London
European Union

Completed

Reactogenicity and Immunogenicity of Cervico-vaginal CN54gp140-hsp70 Conjugate Vaccine (TL01)

HIV Infections

United Kingdom
Liverpool Women's NHS Foundation Trust
University of California, Davis; University of Liverpool

Recruiting

An Exploratory Study of Increased Preterm Arginine INTake (PAINT18) (PAINT18)

Preterm | Nutritional Deficiency | Immune System and Related Disorders

United Kingdom
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Unknown

A Phase 1, Randomized, Blinded, Dose-escalation Study of rAAV1-PG9DP Recombinant AAV Vector Coding for PG9 Antibody in Healthy Male Adults.

HIV Infections

United Kingdom

Clinical Trials on NGLY1 Deficiency in United Kingdom

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Medical Conditions

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Rare Diseases

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