Clinical Trials on NRAS wt Allele
Total 238 results
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Dr.Laurent MineurMerck Serono International SA; BESPIM, CHU Nîmes (data analysis)Unknown
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University of California, San FranciscoTerminatedALK Fusion Protein Expression | Stage III Cutaneous Melanoma | Stage IIIA Cutaneous Melanoma | Stage IIIB Cutaneous Melanoma | Stage IIIC Cutaneous Melanoma | Stage IV Cutaneous Melanoma | ROS1 Fusion Positive | BRAF wt Allele | Invasive Skin Melanoma | MET Fusion Gene Positive | NRAS wt Allele | NTRK1 Fusion... and other conditionsUnited States
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Elicio TherapeuticsRecruitingColorectal Cancer | Pancreatic Ductal Adenocarcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R | KRAS G12V | KRAS G12C | KRAS G12A | KRAS G12S | KRAS G13D | NRAS G12V | NRAS G12C | NRAS G12SUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Genentech, Inc.Active, not recruitingStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | BRAF NP_004324.2:p.V600X | KRAS wt AlleleUnited States
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Lupin Ltd.CompletedA Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsNRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsUnited Kingdom, Netherlands, Belgium
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationUnited States, Australia
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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M.D. Anderson Cancer CenterDNAtrix, Inc.RecruitingRecurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | IDH1 wt AlleleUnited States
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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University Health Network, TorontoCompletedColorectal Cancer | KRAS Wildtype | NRAS Wildtype | BRAF WildtypeCanada
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Cardiff OncologyPfizerRecruitingMetastatic Colorectal Cancer | CRC | KRAS/NRAS MutationUnited States
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University of UtahTerminatedKRAS and NRAS Wild-type Colorectal CancerUnited States
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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Cedars-Sinai Medical CenterNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Recruiting
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Henan Cancer HospitalCompletedWild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
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Calla IVF CenterCompletedImmunomodulatory Drugs | Killer-cell Immunoglobulin-like Receptors (KIRs) | KIR Alleles (KIR AA)Romania
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditionsUnited States
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OnKure, Inc.Active, not recruitingMelanoma | NRAS Gene Mutation | RAS MutationUnited States
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Chinese PLA General HospitalZhejiang UniversityRecruitingSolid Tumor, Adult | KRAS G12D | EphA2 Overexpression | KRAS G12V | KRAS G12CChina
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Karen-Lise Garm SpindlerCompletedColorectal Cancer Metastatic | KRAS Gene Mutation | Circulating Tumor DNA | BRAF Gene Mutation | NRAS Gene Mutation | Epidermal Growth Factor Receptor InhibitorDenmark
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King Saud Medical CityActive, not recruiting
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University of North Carolina, Chapel HillCompletedMale Infertility | Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676United States
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Cairo UniversityRecruiting
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Shanghai Zhongshan HospitalRecruiting
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Tanta UniversityCompleted
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University of ThessalyRecruiting
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D3 Bio (Wuxi) Co., LtdRecruitingKRAS P.G12CAustralia, Korea, Republic of, China, United States, Hong Kong
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xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
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Innovent Biologics (Suzhou) Co. Ltd.Recruiting
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Minia UniversityNot yet recruiting
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Ataturk UniversityNot yet recruiting
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University of PennsylvaniaCompleted
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Dr. Soetomo General HospitalCompleted
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Hunan Province Tumor HospitalRecruitingNon-small Cell Lung Cancer | KRAS G12D | KRAS G12R | KRAS G12V | KRAS G12C | KRAS G12Y | KRAS G13NChina
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Cliniques universitaires Saint-Luc- Université...Completed
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Daping Hospital and the Research Institute of Surgery...UnknownInfant, Newborn, NRDSChina
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Addario Lung Cancer Medical InstituteRecruiting
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
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Boehringer IngelheimCompletedSolid Tumors, KRAS MutationJapan
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Zeynep Kamil Maternity and Pediatric Research and...Enrolling by invitationCesarean Section Complications | ERASTurkey
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Lawson Health Research InstituteNot yet recruitingChest Tube Removal | Lung Surgery | ERASCanada
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS Mutation; SOS1United States, Netherlands, Germany
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Providence Health & ServicesAvailableKRAS G12V Mutant Advanced Epithelial Cancers
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Suzhou Genhouse Bio Co., Ltd.Zhejiang Cancer HospitalNot yet recruitingKRAS G12C Mutant Solid Tumors
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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Vanderbilt University Medical CenterEdwards LifesciencesCompletedColorectal Surgery | Perioperative Care | Quality Improvement | ERASUnited States
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Jiangsu HengRui Medicine Co., Ltd.Not yet recruitingAdvanced KRAS G12D Mutant Solid TumorsChina
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan