Clinical Trials on Neoadjuvant Chemoradiotherapy

Total 259 results

The First Affiliated Hospital with Nanjing Medical...

Recruiting

Omission of ALND in Breast Cancer Patients With Axillary pCR

Breast Cancer | Pathological Complete Response | Axillary Lymph Node Dissection | Neoadjuvant Systemic Therapy | Axillary Lymph

China
Hongqian Guo

Active, not recruiting

Androgen Deprivation Therapy Combined With Docetaxel for High Risk Prostate Cancer

Neoadjuvant Therapy \ High Risk Prostate Cancer \ Docetaxel

China
Shanghai Minimally Invasive Surgery Center

Withdrawn

Anlotinib Hydrochloride Combined With Capeox in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Rectal Cancer | Anlotinib | Neoadjuvant Treatment
Peking University First Hospital

Recruiting

Efficacy and Safety of Combinition of Camrelizumab in Second-line Neoadjuvant Chemotherapy and Adjuvant Therapy

Neoadjuvant Therapy | Cisplatin | Immunotherapy | HER2-negative Breast Cancer | Pathological Complete Response | Vinorelbine

China
Instituto Nacional de Cancer, Brazil

Unknown

Short-course Radiotherapy With Induction and Consolidation Chemotherapy in Patients With Locally Advanced Rectal Cancer (SHORT-ICAR)

Rectal Cancer | Total Neoadjuvant Treatment

Brazil
Zhejiang Cancer Hospital

Unknown

Application of Circulating Tumor DNA Test in the Diagnosis and Treatment of Patients With Advanced Rectal Cancer

Rectal Neoplasms | Neoadjuvant Therapy | Circulating Tumor DNA

China
West China Hospital
Sun Yat-sen University; Peking University Cancer Hospital & Institute; Second... and other collaborators

Recruiting

Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer (COPEC)

Rectal Cancer | Neoadjuvant Chemotherapy

China
Hospital Clinic of Barcelona
Hospital Son Espases; Hospital del Mar; Hospital Universitario La Fe; Instituto... and other collaborators

Unknown

Interval Between Neoadjuvant Therapy and Surgery in the Treatment of Locally Advanced Rectal Cancer (CRONOS) (CRONOS)

Rectal Cancer | Neoadjuvant Therapy

Spain
Peking University
Shanxi Province Cancer Hospital; The First Affiliated Hospital of Nanchang... and other collaborators

Unknown

A Study to Confirm the Accuracy of Locally Advanced Gastric Cancer Diagnosis

Gastric Cancer | Neoadjuvant Therapy | Gastric Cancer Stage | CT

China
National Cancer Center, Korea

Unknown

Preoperative Chemoradiotherapy With Capecitabine Plus Irinotecan in Rectal Cancer

Neoadjuvant Therapy | Rectal Neoplasm

Korea, Republic of
Ascendis Pharma Oncology Division A/S

Recruiting

A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor | Locally Advanced Solid Tumor | Neoadjuvant Melanoma | Head and Neck Squamous Cell Carcinoma HNSCC | HPV-associated Cancers | Neoadjuvant Cutaneous Squamous Cell Carcinoma (cSCC)

United States, Australia, Spain, Netherlands, Korea, Republic of, Taiwan
Yunnan Cancer Hospital
Beijing Bethune Charitable Foundation

Recruiting

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer (ESTIMATE)

Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

China
Samsung Medical Center

Recruiting

Impact of Immuno-Oncologic Agent on Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Triple Negative Breast Cancer | Pembrolizumab | Neoadjuvant Chemotherapy | Tumor Microenvironment

Korea, Republic of
Institut Investigacio Sanitaria Pere Virgili

Not yet recruiting

Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases (PREHABMET)

Neoadjuvant Therapy | Liver Metastases | Prehabilitation

Spain
Seoul National University Hospital

Completed

An Exploration of Candidates for Neoadjuvant Treatment in Resectable Pancreatic Cancer

Pancreatic Cancer | Neoadjuvant
Henan Cancer Hospital

Recruiting

Study of CT and MR in the Gastric Cancer

MRI | Neoadjuvant Therapy | Gastric Cancer Stage | CT

China
Medizinische Hochschule Brandenburg Theodor Fontane
Clinical-Epidemiological Cancer Registry Brandenburg-Berlin

Completed

Survival Benefit of Primary Tumour Resection Compared to Systemic Therapy Alone in Stage IV Colorectal Cancer Patients (SurvSysT)

Colorectal Cancer | Neoadjuvant Systemic Therapy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Phase II Neoadjuvant Pyrotinib Combined With Neoadjuvant Chemotherapy in HER2-low-expressing and HR Positive Early or Locally Advanced Breast Cancer: a Single-arm, Non-randomized, Single-center, Open Label Trial

Breast Cancer | Neoadjuvant Therapy | Hormone Receptor-positive Breast Cancer | HER2-low-expressing Breast Cancer

China
Yonsei University

Unknown

Comparison of Ability of pCLE and WLE for Diagnosis and Cancer Tissue Acquisition in Advanced Gastric Cancer After Chemotherapy Status

Advanced Gastric Cancer | Neoadjuvant Chemotherapy | Palliative Chemotherapy

Korea, Republic of
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

Adaptive Individualized High-Dose Radiotherapy Analysis-REctum-1 (AIDA-RE-1)

Rectal Cancer | Radiotherapy | Neoadjuvant Treatment

Italy
European Institute of Oncology

Recruiting

Vabb After Neoadjuvant Therapy to Avoid Surgery-pCR to Avoid Breast Surgery (BETTY-CRASY)

Breast Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Neoadjuvant Chemotherapy

Italy
Zhejiang Cancer Hospital

Recruiting

DLCS for Predicting Neoadjuvant Chemotherapy Response

Gastric Cancer | Deep Learning | Neoadjuvant Chemotherapy | CT Images | Tumor Regression Grade

China
JIANYANG WANG
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Not yet recruiting

The Effect of Prophylactic TPO Combined With BMS-IMRT to Esophageal Cancer Patients

Esophageal Cancer | Thrombocytopenia | Concurrent Chemoradiotherapy | Intensity-modulated Radiation Therapy

China
Shanghai Minimally Invasive Surgery Center
Wuxi Branch of Ruijin Hospital; Shanghai OneTar Biomedicine Co., Ltd.

Not yet recruiting

The Clinical Efficacy of Drug Sensitive Neoadjuvant Chemotherapy Based on Organoid Versus Traditional Neoadjuvant Chemotherapy in Advanced Rectal Cancer

Neoadjuvant Therapy
Adlai Nortye Biopharma Co., Ltd.

Completed

Preoperative Radiotherapy and E7046 in Rectum Cancer (PRAER 1)

Neoadjuvant Therapy in Rectal Cancer

United States, United Kingdom, Poland
Peking Union Medical College Hospital
Geneplus-Beijing Co. Ltd.

Unknown

Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer

Rectal Cancer, Adenocarcinoma | Neoadjuvant Chemoradiation
Assiut University

Not yet recruiting

Comparative Study Between Shear and Strain Elastography in Monitoring the Response to NAC in Breast Cancer Patients

Monitoring the Response of Breast Cancer to Neoadjuvant Chemotherapy Using SE and SWE
Shanghai Minimally Invasive Surgery Center

Recruiting

Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy

Rectal Cancer | Bevacizumab | Radiotherapy | Neoadjuvant Treatment

China
Shanghai Minimally Invasive Surgery Center

Recruiting

Neoadjuvant Cetuximab + Chemotherapy Combined With Short-course Radiotherapy

Rectal Cancer | Radiotherapy | Neoadjuvant Treatment | Cetuximab

China
Pusan National University Yangsan Hospital

Recruiting

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Urothelial Carcinoma | Neoadjuvant Chemotherapy | Muscle Invasive Bladder Cancer

Korea, Republic of
Fujian Medical University

Completed

Neoadjuvant Treatment Based on Gastric Cancer Molecular Subtyping.

Neoadjuvant Therapy | Advanced Gastric Cancer | Multi-omics Analysis

China
Sun Yat-sen University

Recruiting

Neoadjuvant Chemotherapy Followed by Chemoradiation Versus Chemoradiation for Stage IIIC Cervical Cancer Patients: A Randomized Phase III Trial (N6C)

Cervical Cancer | Neoadjuvant Chemotherapy | Bulky Neoplasm

China
Beijing Chao Yang Hospital

Recruiting

Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer (NACSOC)

Colorectal Cancer | Obstruction | Neoadjuvant Chemotherapy | Stent

China
Jinling Hospital, China
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Adbelizumab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer

Pancreatic Cancer | Neoadjuvant Therapy

China
Sun Yat-sen University

Recruiting

Envafolimab Monotherapy or Envafolimab + CAPEOX as Neoadjuvant Therapy for Locally Advanced Colorectal Cancer

Colon Cancer | Neoadjuvant Therapy | Immunotherapy

China
Peking University Cancer Hospital & Institute

Recruiting

Camrelizumab Plus Apatinib and Temozolomide as Neoadjuvant in High Risk Acral Melanoma

Melanoma | Temozolomide | Apatinib | Camrelizumab | Acral Melanoma | Neoadjuvant | Pathological Response

China
Zhejiang Provincial People's Hospital

Terminated

Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer

Pancreatic Cancer | Neoadjuvant Chemotherapy

China
Peking University First Hospital

Completed

Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China

Breast Cancer | Predictive Value of Tests | Neoadjuvant Therapy | Prognosis | HER2 | Neoplasm Staging | Estrogen Receptor | Histological Grade

China
Chang-Ming Huang, Prof.

Active, not recruiting

Apatinib Combined With SOX Neoadjuvant Therapy for Locally Advanced Gastric Cancer

Neoadjuvant Therapy | SOX | Locally Advanced Gastric Cancer | Apatinib Combined

China
Lithuanian University of Health Sciences

Recruiting

Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer (RECTUM2015)

Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

Lithuania
Beijing Chao Yang Hospital

Recruiting

Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer (NACSOC-02)

Colorectal Cancer | Obstruction | Immunotherapy | Neoadjuvant Chemotherapy | Stent

China
Fudan University

Not yet recruiting

CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer (TORCH-iTNT)

Neoadjuvant Therapy | Locally Advanced Rectal Cancer

China
Seoul National University Hospital

Completed

Clinical Outcomes of Preservation Versus Resection of Portal/Superior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment

Pancreatic Head Cancer Patients Who Underwent Surgery After Neoadjuvant Treatment
Tianjin Medical University Cancer Institute and...
Chongqing University Cancer Hospital; Xiangya Hospital of Central South University and other collaborators

Not yet recruiting

An Open-label, Single-arm, Multicenter Phase II Clinical Study： Evaluating RC48-ADC Combined With Triplizumab in the Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cancer

Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cance
Ruijin Hospital

Recruiting

Toripalimab Combined With Definitive CCRT for LACC Patients

Cervical Cancer | Immunotherapy | Chemoradiotherapy

China
Beijing Chao Yang Hospital

Recruiting

Multi-points and Full-thickness Biopsy in the Diagnosis of cCR After Neoadjuvant Therapy for Rectal Cancer (BIOPSY)

Rectal Cancer | Metastasis | Neoadjuvant Therapy | Complete Remission

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer

Neoadjuvant Therapy | High Risk Prostate Cancer | Locally Advanced Prostate Cancer | Intense Endocrine Therapy

China
Peking Union Medical College Hospital
Peking University People's Hospital; Beijing Friendship Hospital; Cancer Institute... and other collaborators

Unknown

Multicenter, Prospective, RCT：Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.

Rectal Cancer, Adenocarcinoma | Neoadjuvant Chemoradiation
Zhejiang University

Not yet recruiting

Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab (CAPT-02)

Resectable Pancreatic Cancer | Neoadjuvant Chemotherapy
RenJi Hospital

Completed

Neoadjuvant PD-1 Monoclonal Antibody in Cisplatin-ineligible High Risk Upper Tract Urothelial Carcinoma

Neoadjuvant Immunotherapy of Cisplatin-ineligible High Risk Upper Urinary Tract Urothelial Carcinoma

China

Clinical Trials on Neoadjuvant Chemoradiotherapy

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