Clinical Trials on Neoplasms, Hepatic in United Kingdom

Total 50320 results

Delcath Systems Inc.

Unknown

Registry Protocol- Melphalan Percutaneous Hepatic Perfusion for the Treatment of Unresectable Hepatic Malignancy

Hepatic Malignant Neoplasm Primary Non-Resectable

United Kingdom
AdventHealth

Completed

Endoscopic Ultrasound Guided Liver Biopsy

Hepatic Cancer | Hepatic Carcinoma | Hepatic Neoplasm

United States
zr Pharma & GmbH

Completed

Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor

Neoplasms

United Kingdom, Poland, Slovakia
Imperial College London

Completed

Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate

Hepatic Encephalopathy | Cirrhosis | Minimal Hepatic Encephalopathy

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust; University of Sheffield

Unknown

Hepatectomy Risk Assessment With Functional Magnetic Resonance Imaging (HEPARIM)

Liver Failure | Hepatectomy | Liver Metastases | Liver Cancer

United Kingdom
Norgine

Completed

Real World Outcomes Study of Hepatic Encephalopathy Patients' Experience on Rifaximin (PROSPER) (PROSPER)

Hepatic Encephalopathy

United Kingdom
University of Edinburgh
NHS Lothian

Unknown

The Relationship of Initial Liver Profile and Outcome After Transplantation

Liver Failure

United Kingdom
Case Comprehensive Cancer Center

Completed

Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies

Hepatic Malignancies

United States
American College of Radiology
Pennsylvania Department of Health

Terminated

Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI

Colorectal Neoplasm | Hepatic Neoplasm

United States
University of Edinburgh
NHS Lothian; European Society of Organ Transplantation

Completed

Liver Transplantation and Reticuloendothelial Clearance Capacity

Hepatic Insufficiency | Liver Insufficiency

United Kingdom
Imperial College London

Completed

A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency

Liver Disease

United Kingdom
National Institutes of Health Clinical Center (CC)

Completed

Study of New Software Used During Ablations

Liver Cancer | Hepatic Cancer | Neoplasms, Liver | Hepatic Neoplasms

United States
University of Cambridge

Completed

Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus (MuSE)

Esophageal Neoplasms | Barrett Esophagus | Reflux Esophagitis

United Kingdom
Imperial College London
University of London; Royal College of Physicians; Paddington Charitable Estates...

Completed

Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.

Hepatic Encephalopathy | Cirrhosis

United Kingdom
Allegheny Singer Research Institute (also known...

Active, not recruiting

Radiotherapy With Iron Oxide Nanoparticles (SPION) on MR-Linac for Primary & Metastatic Hepatic Cancers

Liver Neoplasms | Hepatocellular Carcinoma | Liver Metastases | Liver Cancer | Liver Carcinoma | Hepatocellular Cancer | Hepatic Cirrhosis | Hepatic Carcinoma | Hepatic Atrophy

United States
King's College Hospital NHS Trust
King's College London

Completed

Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy (RIFSYS)

Liver Cirrhosis | Hepatoencephalopathy, Early Fatal Progressive

United Kingdom
Daiichi Sankyo, Inc.

Completed

Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

Moderate Hepatic Impairment

United States
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Advanced Cancer and Liver Dysfunction

Malignant Neoplasm | Hepatic Complications

United States
Guy's and St Thomas' NHS Foundation Trust
King's College London

Completed

Safety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients (ThRIL)

End-stage Liver Disease

United Kingdom
Imperial College London

Completed

Adult Stem Cell Therapy in Liver Insufficiency

Liver Cirrhosis

United Kingdom
Rutgers, The State University of New Jersey

Completed

Mobilization of Mesenchymal Stem Cells During Liver Transplantation

Liver Failure | Liver Neoplasm

United States
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Haemostatic Markers in Cardiopulmonary Bypass

Cardiopulmonary Bypass Surgery | Unfractionated Heparin

United Kingdom
University of Leicester
University of Nottingham; University Hospitals, Leicester

Recruiting

Tissue Models for Invasive Disease (TIMID) (TIMID)

Spleen; Septic

United Kingdom
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
National Cancer Institute (NCI)

Completed

TKM 080301 for Primary or Secondary Liver Cancer

Colorectal Cancer With Hepatic Metastases | Pancreas Cancer With Hepatic Metastase | Gastric Cancer With Hepatic Metastase | Breast Cancer With Hepatic Metastase | Ovarian Cancer With Hepatic Metastase

United States
Imperial College London
Pelican Cancer Foundation

Recruiting

Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE) (SERENADE)

Colorectal Neoplasms | Neoplasm Metastases | Hepatic Neoplasms

United Kingdom
Amgen

Completed

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Hepatic Impairment | Solid Tumors | Hematologic Malignancies

United Kingdom, Netherlands, United States, France
H3 Biomedicine Inc.
Eisai Inc.

Completed

Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Advanced Hepatocellular Carcinoma | Liver Cancer | Hepatic Cancer | Hepatic Carcinoma

France, United States, Belgium, Spain, Taiwan, Korea, Republic of, Russian Federation, Canada, Italy, Singapore, United Kingdom
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
St George's, University of London
King's College Hospital NHS Trust

Recruiting

S100A8/A9 and Innate Immunity in Liver Disease

Infections | Cirrhosis, Liver | Ascites Hepatic | Immune Suppression | Liver Failure, Acute on Chronic

United Kingdom
King's College London

Unknown

Microcirculatory Guided Goal Directed Fluid Therapy in Septic Shock; a Feasibility Study (MICRORESUS)

Septic Shock

United Kingdom
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Rigshospitalet, Denmark

Completed

A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure

Acute Liver Failure

Denmark, Finland, United Kingdom
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
University of Nottingham
Mediplus Ltd UK; Enteric healthcare technology Co-operative

Completed

Evaluation of 'Melody' Paracentesis Device for Ascites Therapy (EMPATHY)

Ascites Hepatic | Cirrhosis and Chronic Liver Disease

United Kingdom
Lisa H. Butterfield, Ph.D.
National Cancer Institute (NCI)

Terminated

Immunization With AFP + GM CSF Plasmid Prime and AFP Adenoviral Vector Boost in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer | Cancer of Liver | Hepatoma | Hepatocellular Cancer | Hepatic Cancer | Liver Cell Carcinoma | Cancer, Hepatocellular | Liver Cancer, Adult | Liver Cell Carcinoma, Adult | Cancer of the Liver | Neoplasms, Liver | Hepatic Neoplasms | Neoplasms, Hepatic

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Quell Therapeutics Limited

Recruiting

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients (LIBERATE)

Liver Diseases | Liver Failure | Rejection; Transplant, Liver

Belgium, United Kingdom, Spain
Ethicon, Inc.

Completed

The EVARREST® Paediatric Mild/Moderate Liver and Soft Tissue Bleeding Study

Hemorrhage | Soft Tissue Bleeding | Hepatic Parenchyma Bleeding

United Kingdom, Belgium
Manchester University NHS Foundation Trust
University of Manchester

Recruiting

Strong Albumin Solutions in Patients With Septic Shock (SWIPE2)

Sepsis | Septic Shock | Shock, Toxic

United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Assessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Colorectal, and Gastro-oesophageal Cancer (VERVE)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Oesophageal Cancer | Hepato-Biliary Carcinoma in Situ Nos

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Memorial Sloan Kettering Cancer Center
Wake Forest University

Completed

A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic Malignancy

Hepatic Cancer

United States
University of Louisville

Withdrawn

Direct Peritoneal Resuscitation Plus Conventional Resuscitation

Hepatic Cancer

United States
Takeda

Completed

Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment

Severe Hepatic Impairment

United States
Bausch Health Americas, Inc.

Terminated

Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects

Severe Hepatic Impairment

United States
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Reflux Oesophagitis

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Reflux Oesophagitis

United Kingdom

Clinical Trials on Neoplasms, Hepatic in United Kingdom

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