Clinical Trials on Neoplasms, Gastrointestinal Tract

Total 192622 results

Margaret Ragni
National Heart, Lung, and Blood Institute (NHLBI); Duke University; University...

Terminated

Minimize Menorrhagia in Women With Von Willebrand Disease (VWDMin)

Von Willebrand Diseases

United States
LMC Diabetes & Endocrinology Ltd.
Novo Nordisk Canada Inc.

Completed

Impact of GLP-1 RAs Compared to Basal Insulin Start in Patients Living With Type 2 Diabetes and Chronic Kidney Disease

Chronic Kidney Diseases | Type 2 Diabetes

Canada
Universitaire Ziekenhuizen KU Leuven

Completed

The Prevalence of Foot Complaints/Problems and Ulcers in a Pre-dialysis Population

Diabetes Mellitus | Foot Ulcer | Chronic Kidney Diseases | Pre-dialysis

Belgium
University of Nebraska

Completed

Arteriovenous Fistula Tissue Bank for Pre- and Post-Fistula Placement Specimens

Kidney Failure, Chronic

United States
University of Wisconsin, Madison
Johns Hopkins University; University of Colorado, Denver; Northwestern University and other collaborators

Active, not recruiting

A Communication Tool to Assist Older Adults Facing Dialysis Choices

Kidney Diseases | Kidney Failure, Chronic | Communication | End-Stage Renal Disease | Palliative Care | End of Life | Dialysis | Renal Dialysis | Decision Making | Decision Aid | Decision Support Techniques | Nephrologists | Late-Stage Renal Disease | Life-Supporting Treatments

United States
University of Campania "Luigi Vanvitelli"

Completed

Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases. (InflaMent)

Mental Disorders | Psoriasis | Hiv | Atopic Dermatitis | Hidradenitis Suppurativa | HBV | Chronic Infectious Disease | Chronic Skin Disease

Italy
Novo Nordisk A/S

Withdrawn

Safety and Efficacy Study of NovoRapid™ in Patients With Coexisting Diabetes and Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1 | Chronic Kidney Disease
Bayer

Completed

A Study Using Surveys to Learn More About Treatment With Steroidal Mineralocorticoid Receptor Antagonists, How They Are Used, What Side Effects They Have, and How Satisfied People Who Receive Them Are in the US

Heart Failure | Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States
Weill Medical College of Cornell University
The Rogosin Institute

Enrolling by invitation

Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
University of California, San Francisco
California Institute for Regenerative Medicine (CIRM)

Enrolling by invitation

In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)

Hemoglobinopathies | Alpha Thalassemia Major | Thalassemia Major | Fetal Hydrops | Hemoglobinopathy; With Thalassemia | Fetal Anemia | Alpha; Thalassemia | Thalassemia Alpha | A-Thalassemia

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

Korea, Republic of, Canada, United States, Australia, Japan, United Kingdom, Sweden
University of Illinois at Chicago
Merck Sharp & Dohme LLC

Active, not recruiting

Zepatier in Patients With Substance Use

Hepatitis C | Hiv | Substance Use Disorders | Coinfection, HIV

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Pneumococcal Immunisation | Hepatitis B Immunisation | Polio Immunisation | Haemophilus Influenzae Type B Immunisation | Rotavirus Immunisation

Thailand
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection

HIV Infections | AIDS Dementia Complex

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Pilot Study Evaluating Penicillin G and Ceftriaxone as Therapies for Presumed Neurosyphilis in HIV Seropositive Individuals

HIV Infections | Neurosyphilis

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection

HIV Infections | Infection, Human Immunodeficiency Virus

Mexico, Peru, Thailand, South Africa, Russian Federation, Argentina, Brazil
National Human Genome Research Institute (NHGRI)

Terminated

The NIH UNI Study: Urea Cycle Disorders, Nutrition and Immunity

Citrullinemia | Argininosuccinic Aciduria | Hyperargininemia | Ornithine Carbamoyltransferase Deficiency | Carbamoyl-Phosphate Synthase I Deficiency | N-Acetylglutamate Synthase Deficiency

United States
Swiss Neonatal Network
Swiss National Science Foundation

Completed

Does Erythropoietin Improve Outcome in Very Preterm Infants?

Cerebral Palsy | Periventricular Leukomalacia | Intracranial Hemorrhage | Developmental Psychomotor Disorders

Switzerland
Ulla Feldt-Rasmussen

Completed

Fabry: Renal Function During Long-term ERT by 51Cr-EDTA Clearance

Fabry Disease

Denmark
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Eunice Kennedy Shriver National Institute of Child...
National Human Genome Research Institute (NHGRI)

Completed

Turner Syndrome: Genotype and Phenotype

Turner's Syndrome

United States
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants (MgSO4)

Cerebral Palsy | Intracranial Hemorrhages | Infant, Small for Gestational Age | Infant, Premature | Leukomalacia, Periventricular | Infant, Low Birth Weight | Infant, Newborn

United States
Washington University School of Medicine

Completed

The Effect of HPV Vaccination on Recurrence Rates in HIV Patients With Condylomata

HIV Infections | HIV Positive | Anal Condylomata | Anal Warts

United States
Gilead Sciences

Completed

A Phase 3, Open-label Study to Investigate the Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2, 3 and 4 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected Adults

Chronic Hepatitis C | Human Immunodeficiency Virus

France, Italy, United Kingdom, Germany, Spain, Australia
C. T. Lamont Primary Care Research Centre
Ottawa Heart Institute Research Corporation; Dept of Family Medicine, Faculty... and other collaborators

Completed

Improved Delivery of Cardiovascular Care Through Outreach Facilitation (IDOCC)

Stroke | Hypertension | Cardiovascular Disease | Diabetes | Dyslipidemia | Chronic Kidney Disease | Transient Ischemic Attacks

Canada
Mahidol University

Completed

Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy

HIV/AIDS | Cryptococcal Meningitis

Thailand
Sheba Medical Center

Unknown

S100B as a Marker of Brain Injury of Preterm Infants (PTS100B)

Brain Injuries | Premature Birth | Developmental Disabilities | Leukomalacia Periventricular

Israel
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Cedars-Sinai Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Unknown

Pulmonary Disease and Exercise Tolerance in Boys With Fabry Disease

Fabry Disease

United States
Fundacion para la Investigacion Biomedica del Hospital...
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of Raltegravir in Human Immunodeficiency Virus/Hepatitis C Virus (HIV/VHC) Coinfected Patients With Advanced (Child-Pugh C) Hepatic Cirrhosis (LIVERAL)

Hepatitis C | Human Immunodeficiency Virus

Spain
Assiut University

Completed

N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement

Renal Dysfunction | Cardiac Surgery for Rheumatic Valvular Heart Disease

Egypt
Canadian Immunodeficiency Research Collaborative
Pur Medical Corporation

Completed

Safety, Efficacy and Psychological Effects of Treating Antiretroviral Drug-Induced Facial Lipoatrophy With Bio-Alcamid

Human Immunodeficiency Virus | Facial Lipoatrophy

Canada
Regeneron Pharmaceuticals

Completed

Rilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)

Genetic Diseases, Inborn | Familial Cold Autoinflammatory Syndrome (FCAS) | Familial Cold Urticaria | Muckle-Wells Syndrome (MWS)

United States
Karolinska Institutet
The Swedish Research Council; Hoffmann-La Roche

Completed

Interactions of Hepatitis C Viral (HCV) Dynamics and Immune Activation in HIV Coinfected Patients During HCV Treatment (DICO)

Chronic Hepatitis C | Human Immunodeficiency Virus

Sweden
Shaman Pharmaceuticals

Completed

Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)

HIV Infections | Herpes Simplex

United States, Puerto Rico
Pfizer

Completed

Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States, Canada
University of Regensburg

Recruiting

A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD

Sickle Cell Disease | Sickle Cell Anemia | Sickle Cell Disorders | HbS Disease | Hemoglobin S Disease | Sickling Disorder Due to Hemoglobin S

Germany, Austria
Isfahan University of Medical Sciences

Completed

Effect of High Protein Diet on Adiponectin and Inflammation Among Overweight and Obese Children

Tangier Disease | Body Mass Index Quantitative Trait Locus 5 Disorder

Iran, Islamic Republic of
University Health Network, Toronto
Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)...

Not yet recruiting

TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study (T-REX HMB)

Venous Thromboembolism | Venous Thromboses | Anticoagulants and Bleeding Disorders | Heavy Menstrual Bleeding
Mario Negri Institute for Pharmacological Research

Not yet recruiting

Blood Flow Conditions and Sounds in AVFs (APOLLO)

End Stage Renal Disease

Italy
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
Dr Cipto Mangunkusumo General Hospital
Fakultas Kedokteran Universitas Indonesia; Dinas Kesehatan DKI Jakarta

Recruiting

Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta (MONAS)

Pregnancy Complications | Preterm Birth | Preeclampsia | Asphyxia Neonatorum | Low; Birthweight, Extremely (999 Grams or Less) | Maternal Death | IUGR | Neonatal Death | Pregnancy Hemorrhage | Intrauterine Infection

Indonesia
Unity Health Toronto

Not yet recruiting

A Pilot Crossover Trial of Prophylactic Wilate Compared to Placebo for Heavy Menstrual Bleeding in Patients With VWD (EMPOWER)

Von Willebrand Diseases
University of Roma La Sapienza
University of Milan; Azienda Policlinico Umberto I; Pavia IRCCS Mondino di Pavia

Recruiting

Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia (PSYCHOFIBRO)

Fibromyalgia | Vulvodynia | Chronic Migraine, Headache

Italy
Novo Nordisk A/S

Recruiting

A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

Obesity | Type 2 Diabetes | Chronic Kidney Disease

United States, Spain, Poland, Thailand, India, France, Argentina, Canada, Japan, Greece, Slovakia, Hungary, Brazil
Brugmann University Hospital

Recruiting

Arteriovenous Fistula Maturation in Hemodialysis Patients With or Without Positive Antiphospholipid Antibodies

Chronic Kidney Diseases

Belgium
Vanderbilt University Medical Center

Recruiting

The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease (GLAM HIV NAFLD)

HIV | Non-Alcoholic Fatty Liver Disease | Metabolic-Associated Steatotic Liver Disease

United States
Rhode Island Hospital

Recruiting

Combined Injectable Treatment for HIV and OUD (CHOICE)

Opioid Use Disorder | Human Immunodeficiency Virus

United States

Clinical Trials on Neoplasms, Gastrointestinal Tract

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