Clinical Trials on Neoplasms, Second Primary

Total 148254 results

Bayer

Completed

A Study Using Surveys to Learn More About Treatment With Steroidal Mineralocorticoid Receptor Antagonists, How They Are Used, What Side Effects They Have, and How Satisfied People Who Receive Them Are in the US

Heart Failure | Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States
Weill Medical College of Cornell University
The Rogosin Institute

Enrolling by invitation

Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
University of California, San Francisco
California Institute for Regenerative Medicine (CIRM)

Enrolling by invitation

In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)

Hemoglobinopathies | Alpha Thalassemia Major | Thalassemia Major | Fetal Hydrops | Hemoglobinopathy; With Thalassemia | Fetal Anemia | Alpha; Thalassemia | Thalassemia Alpha | A-Thalassemia

United States
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

Korea, Republic of, Canada, United States, Australia, Japan, United Kingdom, Sweden
University Hospital, Angers

Completed

Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS (DELTA)

Acute Lung Injury | ARDS (Acute Respiratory Distress Syndrome) | Positive End Expiratory Pressure (PEEP) | Electrical Impedance Tomography (EIT)

France
University of Illinois at Chicago
Merck Sharp & Dohme LLC

Active, not recruiting

Zepatier in Patients With Substance Use

Hepatitis C | Hiv | Substance Use Disorders | Coinfection, HIV

United States
Rush University Medical Center

Completed

Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS

Acute Respiratory Distress Syndrome | Corona Virus Infection | High Flow Nasal Cannula | Prone Positioning

United States
University of California, San Francisco

Completed

Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension

HIV Infections | HIV Infection | Pulmonary Hypertension | Endothelial Function

United States
Central Hospital, Nancy, France

Completed

Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome (MSC-COVID19)

COVID19 ARDS

France
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection

HIV Infections | AIDS Dementia Complex

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Pilot Study Evaluating Penicillin G and Ceftriaxone as Therapies for Presumed Neurosyphilis in HIV Seropositive Individuals

HIV Infections | Neurosyphilis

United States
Assistance Publique - Hôpitaux de Paris

Completed

FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia (FX-COVID)

Pneumonia | Covid19 | Ards

France
ViiV Healthcare
GlaxoSmithKline

Completed

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection

HIV Infections | Infection, Human Immunodeficiency Virus

Mexico, Peru, Thailand, South Africa, Russian Federation, Argentina, Brazil
Unity Health Toronto
Defence Research and Development Canada

Unknown

RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study

COVID | Ischemia Limb | Acute Respiratory Distress Syndrome | Acute Lung Injury | Corona Virus Infection
Puerta de Hierro University Hospital
Hospital General Universitario Gregorio Marañon; Hospital Universitario 12... and other collaborators

Unknown

Spanish Registry of Pregnant Women With COVID-19 (OBS COVID)

Covid19 | Pregnancy Complications | Stillbirth | Premature Rupture of Membrane | Abruptio Placentae | Prelabor Rupture of Membranes

Spain
Hospital Sirio-Libanes
Hospital Israelita Albert Einstein; Ache Laboratorios Farmaceuticos S.A.; Hospital... and other collaborators

Terminated

COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III (CoDEX)

Coronavirus Infection | Pneumonia, Viral | Acute Respiratory Distress Syndrome

Brazil
Azienda USL Toscana Nord Ovest
Azienda Ospedaliero, Universitaria Pisana; Azienda Ospedaliera Universitaria... and other collaborators

Unknown

Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection (RESPIRE)

Severe Acute Respiratory Syndrome Coronavirus 2
University Hospital Schleswig-Holstein
University College, London; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

Continuous Regional Analysis Device for Neonate Lung (CRADL)

Acute Respiratory Distress Syndrome | Infant Respiratory Distress Syndrome | Acute Bronchiolitis

Netherlands, Finland, Cyprus
Rigshospitalet, Denmark

Terminated

Lung and Systemic Inflammation in the Critically Ill Patient

Sepsis | Acute Respiratory Distress Syndrome (ARDS) | Systemic Inflammatory Response Syndrome (SIRS)

Denmark
Swiss Neonatal Network
Swiss National Science Foundation

Completed

Does Erythropoietin Improve Outcome in Very Preterm Infants?

Cerebral Palsy | Periventricular Leukomalacia | Intracranial Hemorrhage | Developmental Psychomotor Disorders

Switzerland
Ulla Feldt-Rasmussen

Completed

Fabry: Renal Function During Long-term ERT by 51Cr-EDTA Clearance

Fabry Disease

Denmark
Montefiore Medical Center

Completed

Effect of Supine or Prone Position After Caesarean Birth

Transient Tachypnea of the Newborn | Respiratory Distress | Delayed Transition of the Newborn | Persistent Pulmonary Hypertension

United States
Indonesia University

Unknown

The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates

Hyaline Membrane Disease | Necrotizing Enterocolitis of Newborn

Indonesia
Eunice Kennedy Shriver National Institute of Child...
National Human Genome Research Institute (NHGRI)

Completed

Turner Syndrome: Genotype and Phenotype

Turner's Syndrome

United States
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
NICHD Neonatal Research Network
Canadian Institutes of Health Research (CIHR); National Center for Research... and other collaborators

Terminated

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns (Early iNO)

Respiratory Insufficiency | Hypertension, Pulmonary | Pneumonia, Aspiration | Persistent Fetal Circulation Syndrome | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants (MgSO4)

Cerebral Palsy | Intracranial Hemorrhages | Infant, Small for Gestational Age | Infant, Premature | Leukomalacia, Periventricular | Infant, Low Birth Weight | Infant, Newborn

United States
ANRS, Emerging Infectious Diseases

Unknown

Interaction Between High Dose Rifampicine and Efavirenz in Pulmonary Tuberculosis and HIV Co-infection (RIFAVIRENZ)

HIV | Tuberculosis

Uganda
Colorado State University
National Institute for Biomedical Imaging and Bioengineering (NIBIB)

Completed

Electrical Impedance Imaging of Patients on Mechanical Ventilation

Pneumothorax | Emphysema | Hyperinflation | Acute Respiratory Distress Syndrome | Pulmonary Edema | Pleural Effusion | Atelectasis | Pulmonary Contusion

United States
Washington University School of Medicine

Completed

The Effect of HPV Vaccination on Recurrence Rates in HIV Patients With Condylomata

HIV Infections | HIV Positive | Anal Condylomata | Anal Warts

United States
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Tuberculosis in a Multiethnic Inner City Population

HIV Infections | Acquired Immunodeficiency Syndrome | Lung Diseases | Tuberculosis | Mycobacterium Tuberculosis
Gilead Sciences

Completed

A Phase 3, Open-label Study to Investigate the Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2, 3 and 4 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected Adults

Chronic Hepatitis C | Human Immunodeficiency Virus

France, Italy, United Kingdom, Germany, Spain, Australia
C. T. Lamont Primary Care Research Centre
Ottawa Heart Institute Research Corporation; Dept of Family Medicine, Faculty... and other collaborators

Completed

Improved Delivery of Cardiovascular Care Through Outreach Facilitation (IDOCC)

Stroke | Hypertension | Cardiovascular Disease | Diabetes | Dyslipidemia | Chronic Kidney Disease | Transient Ischemic Attacks

Canada
Mahidol University

Completed

Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy

HIV/AIDS | Cryptococcal Meningitis

Thailand
Sheba Medical Center

Unknown

S100B as a Marker of Brain Injury of Preterm Infants (PTS100B)

Brain Injuries | Premature Birth | Developmental Disabilities | Leukomalacia Periventricular

Israel
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
University Hospital, Clermont-Ferrand

Completed

Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis | Mechanical Ventilation

France
Fundacion para la Investigacion Biomedica del Hospital...
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of Raltegravir in Human Immunodeficiency Virus/Hepatitis C Virus (HIV/VHC) Coinfected Patients With Advanced (Child-Pugh C) Hepatic Cirrhosis (LIVERAL)

Hepatitis C | Human Immunodeficiency Virus

Spain
Assiut University

Completed

N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement

Renal Dysfunction | Cardiac Surgery for Rheumatic Valvular Heart Disease

Egypt
Canadian Immunodeficiency Research Collaborative
Pur Medical Corporation

Completed

Safety, Efficacy and Psychological Effects of Treating Antiretroviral Drug-Induced Facial Lipoatrophy With Bio-Alcamid

Human Immunodeficiency Virus | Facial Lipoatrophy

Canada
Clarassance, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome in Premature Infant

United States
Karolinska Institutet
The Swedish Research Council; Hoffmann-La Roche

Completed

Interactions of Hepatitis C Viral (HCV) Dynamics and Immune Activation in HIV Coinfected Patients During HCV Treatment (DICO)

Chronic Hepatitis C | Human Immunodeficiency Virus

Sweden
Shaman Pharmaceuticals

Completed

Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)

HIV Infections | Herpes Simplex

United States, Puerto Rico
Pfizer

Completed

Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States, Canada
LyphoMed

Completed

A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
University Health Network, Toronto
Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)...

Not yet recruiting

TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study (T-REX HMB)

Venous Thromboembolism | Venous Thromboses | Anticoagulants and Bleeding Disorders | Heavy Menstrual Bleeding
Mario Negri Institute for Pharmacological Research

Not yet recruiting

Blood Flow Conditions and Sounds in AVFs (APOLLO)

End Stage Renal Disease

Italy
Assembly Biosciences

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India

Clinical Trials on Neoplasms, Second Primary

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