Clinical Trials on Nervous System Lyme Borreliosis in United States

Total 32695 results

Sequenom, Inc.
PRA Health Sciences

Completed

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Pregnancy | Down Syndrome | Aneuploidy | Edwards Syndrome

United States, France
Sunovion

Completed

A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and Insomnia

Insomnia | Major Depressive Disorder

France, Poland, Russian Federation, United Kingdom, Austria, Hungary, Croatia, Romania, Serbia, Ukraine
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Molecular, Pathologic and MRI Investigation of the Prognostic and Redictive Importance of Extramural Venous Invasion in Rectal Cancer (MARVEL) Trial (MARVEL)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland
GlaxoSmithKline

Completed

A Combined Tdap Vaccine Used As A Booster Compared To Licensed Td Vaccine

Tetanus | Diphtheria | Acellular Pertussis

United States
University of Nebraska

Recruiting

Integrated Cancer Repository for Cancer Research (iCaRe2)

Melanoma | Sarcoma | Kidney Cancer | Leukemia | Breast Cancer | Laryngeal Cancer | Hypopharyngeal Cancer | Nasopharyngeal Cancer | Multiple Myeloma | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Ovarian Cancer | Lynch Syndrome | Lung Cancer | Rectal Cancer | Prostate Cancer | Gastrointestinal... and other conditions

United States
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years

Tetanus | Diphtheria | Acellular Pertussis

United States
European Paediatric Soft Tissue Sarcoma Study Group
Children's Cancer and Leukaemia Group; Dutch Childhood Oncology Group; Italian... and other collaborators

Unknown

Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma

Sarcoma | Childhood Malignant Fibrous Histiocytoma of Bone

Ireland, United Kingdom, Spain, Austria, Belgium, Denmark, France, Sweden, Switzerland
Medtronic Cardiac Rhythm and Heart Failure

Completed

Improve Sudden Cardiac Arrest Study

Ventricular Arrythmia | Sudden Cardiac Arrest

China, Korea, Republic of, Taiwan, Argentina, Colombia, Singapore, Russian Federation, India, South Africa, Malaysia, United Arab Emirates, Belarus, Brazil, Egypt, Mexico, Tunisia
Restech Srl
Uppsala University; University Hospital of North Norway; University of Lincoln; University of Liverpool and other collaborators

Completed

Clinical Trials for Elderly Patients With Multiple Disease (CHROMED)

Chronic Obstructive Pulmonary Disease (COPD) | Congestive Heart Failure (CHF) | Sleep Disordered Breathing (SDB)

Spain, United Kingdom, Sweden, Estonia, Slovenia
Momentum Data
Optimum Patient Care

Completed

Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health

Schizophrenia | Inflammatory Bowel Diseases | Bipolar Disorder | Sleep Disturbance | Suicide, Attempted | Attention Deficit Hyperactivity Disorder | Post-traumatic Stress Disorder | Self Harm | Body Image Disorder | Eating Disorders | Adjustment Disorders | Anxiety Disorder | Depressive Episode | Behavioral Disorder | Psychological Disorder and other conditions

United Kingdom
Quark Pharmaceuticals

Terminated

Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

Non Arteritic Anterior Ischemic Optic Neuropathy

United States, Australia, Germany, China, India, Italy, Singapore, Israel
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma

Sarcoma | Myelodysplastic Syndromes | Leukemia

United States, Canada, Australia
NRG Oncology
National Cancer Institute (NCI)

Completed

Copanlisib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Endometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Recurrent Uterine Corpus Cancer | Metastatic Endometrioid Adenocarcinoma

United States
Celldex Therapeutics

Completed

Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma (ACT IV)

Glioblastoma | Gliosarcoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component

United States, Canada, Australia, Israel, Taiwan, United Kingdom, Belgium, France, Spain, Germany, Austria, Brazil, Colombia, Czechia, Greece, Hungary, India, Italy, Mexico, Netherlands, New Zealand, Peru, Switzerland, Thailand
Sunovion

Completed

Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia

Insomnia | Attention Deficit Hyperactivity Disorder

United States
Janssen Research & Development, LLC
Bayer

Completed

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure (COMMANDER HF)

Coronary Artery Disease | Heart Failure

United States, France, Poland, Ukraine, United Kingdom, China, Germany, Spain, Argentina, Mexico, Portugal, Bulgaria, Malaysia, Romania, Russian Federation, South Africa, Turkey, Korea, Republic of, Japan, Canada, Netherlands, Den... and more
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Choriocarcinoma | Embryonal Carcinoma | Mixed Germ Cell Tumor | Central Nervous System Nongerminomatous Germ Cell Tumor | Immature Teratoma | Malignant Teratoma | Pineal Region Germ Cell Tumor | Pineal Region Immature Teratoma | Pineal Region Yolk Sac Tumor | Suprasellar Germ Cell Tumor

United States, Australia, Canada, New Zealand
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Institute of Cancer Research, United Kingdom
Verastem, Inc.

Active, not recruiting

Phase I Trial of Defactinib and VS-6766. (FRAME)

Pancreatic Cancer | NSCLC | Low Grade Serous Ovarian Cancer | Endometrioid Carcinoma

United Kingdom
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion (RAPTOR)

Branch Retinal Vein Occlusion

China, Austria, Czechia, Russian Federation, Taiwan, United Kingdom, Canada, Japan, United States, France, Israel, Germany, Italy, Hong Kong, Spain, Denmark, Slovakia, Puerto Rico, Switzerland
Jazz Pharmaceuticals

Completed

"A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA"

Obstructive Sleep Apnea | Narcolepsy

United States, France, Canada, Germany, Netherlands, Finland
PTC Therapeutics

Completed

Study of Ataluren for Previously Treated Participants With Nonsense Mutation Duchenne/Becker Muscular Dystrophy (nmDBMD) in Europe, Israel, Australia, and Canada

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dystrophinopathy

United Kingdom, Canada, Germany, Spain, Sweden, Italy, Australia, Belgium, France, Israel
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent... and other conditions

United States, Puerto Rico
Royal Marsden NHS Foundation Trust
Pelican Cancer Foundation

Unknown

Low Rectal Cancer Study (MERCURY II) (MERCURY II)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

United Kingdom, Germany, Serbia
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia

Pathological Myopia

Germany, India, Japan, Turkey, Austria, Switzerland, Italy, Lithuania, Hungary, France, Slovakia, United Kingdom, Korea, Republic of, Portugal, Hong Kong, Canada, Singapore, Spain, Latvia, Poland
Takeda

Completed

Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome (EXAMINE)

Diabetes Mellitus, Type 2 | Acute Coronary Syndrome

United States, France, Italy, Poland, Ukraine, United Kingdom, Belgium, Germany, Hong Kong, Argentina, Chile, Colombia, Israel, Mexico, Portugal, Bulgaria, Malaysia, Romania, Serbia, South Africa, Japan, Canada, Finland, Taiwan, Korea,... and more
Gilead Sciences

Completed

Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina (TERISA)

Coronary Artery Disease | Type 2 Diabetes Mellitus | Angina Pectoris

Canada, Slovenia, United States, Israel, Germany, Georgia, Russian Federation, Czech Republic, Belarus, Bulgaria, Poland, Serbia, Slovakia, Ukraine
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment

Breast Cancer | Arthralgia | Hot Flashes | Sexual Dysfunction | Musculoskeletal Complications

United States, Puerto Rico
Sanofi Pasteur, a Sanofi Company

Completed

Surveillance Program to Determine Product Specific Rates of Invasive Hib Disease

Pertussis | Tetanus | Diphtheria | Polio | Haemophilus Infections

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

Pain | Neuropathy | Stage IIIA Fallopian Tube Cancer | Stage IIIA Ovarian Cancer | Stage IIIA Primary Peritoneal Cancer | Stage IIIB Fallopian Tube Cancer | Stage IIIB Ovarian Cancer | Stage IIIB Primary Peritoneal Cancer | Stage IIIC Fallopian Tube Cancer | Stage IIIC Ovarian Cancer | Stage IIIC Primary... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma

Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Dermatofibrosarcoma Protuberans | Adult Angiosarcoma | Adult Epithelioid Sarcoma | Adult Extraskeletal Osteosarcoma | Adult Fibrosarcoma | Adult Leiomyosarcoma and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico
GlaxoSmithKline

Completed

Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine.

Tetanus | Diphtheria | Acellular Pertussis | Diphtheria-Tetanus-acellular Pertussis Vaccines

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features. (ATTAIN 267)

Adolescent Schizophrenia | Child or Adolescent Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features

India, United States, Bulgaria, Croatia, Hungary, Malaysia, Philippines, Poland, Romania, Russian Federation, Serbia, Taiwan, Ukraine
Ole Frobert, MD, PhD
Uppsala University; Sanofi Pasteur, a Sanofi Company; Swedish Heart Lung Foundation and other collaborators

Completed

Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis (IAMI)

Myocardial Infarction | Heart Failure | Stroke | Influenza, Human | Influenza Vaccines

Denmark, United Kingdom, Sweden, Australia, Bangladesh, Czechia, Latvia, Norway
NSABP Foundation Inc
National Cancer Institute (NCI)

Unknown

Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32

Depression | Breast Cancer | Fatigue | Sleep Disorders

United States, Canada
CENTOGENE GmbH Rostock

Completed

Epidemiological Analysis for Hereditary Angioedema Disease (EHA)

Abdominal Pain | Functional Abdominal Pain

United Kingdom, Germany, Turkey, Poland, Italy, Japan
Novartis Pharmaceuticals

Terminated

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (RAVEN)

Central Retinal Vein Occlusion

China, Czechia, Germany, Russian Federation, Turkey, United States, Australia, Canada, Spain, United Kingdom, Thailand, Israel, Netherlands, Italy, Hungary, France, Greece, Puerto Rico, Malaysia, Japan
Otsuka Pharmaceutical Development & Commercialization...

Completed

8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE)

Autosomal Dominant Polycystic Kidney Disease

United States
Royal Free Hospital NHS Foundation Trust
Fisher and Paykel Healthcare; Royal Free Charity

Active, not recruiting

Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom

Chronic Obstructive Pulmonary Disease | Chronic Hypercapnic Respiratory Failure | Health-related Quality of Life | Obesity Hypoventilation Syndrome (OHS) | Nasal High Flow

United Kingdom
Pfizer

Completed

Study Of The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (FEENICS)

Diabetic Foot Ulcer

Canada, Greece, Austria, Finland, Poland, Sweden, Russian Federation, Norway, Spain, Italy, United Kingdom, Denmark, Lithuania, Belgium, Germany, Ukraine, Czechia
National Cancer Institute (NCI)

Completed

Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Central Retinal Vein Occlusion (CRVO) (COMRADE-C)

Central Retinal Vein Occlusion | Macular Edema | Visual Impairment

Germany, United Kingdom, Hungary, Poland
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

Down Syndrome | Myeloid Leukemia Associated With Down Syndrome | B Acute Lymphoblastic Leukemia Associated With Down Syndrome

United States
Barts & The London NHS Trust
Queen Mary University of London

Recruiting

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure (CLEVERER)

Respiratory Failure | Acute Respiratory Distress Syndrome | Critical Illness Myopathy | Intensive Care Unit Syndrome | Cardiac Failure | Intensive Care (ICU) Myopathy | Intensive Care Neuropathy

United Kingdom
Verinata Health, Inc.

Completed

Comparison of Aneuploidy Risk Evaluations (CARE)

Pregnancy | Down Syndrome | Edwards Syndrome | Patau Syndrome | Turners Syndrome

United States
NRG Oncology
National Cancer Institute (NCI)

Completed

Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Undergoing Surgery

Fallopian Tube Carcinoma | Endometrial Serous Adenocarcinoma | Ovarian Carcinoma | Malignant Female Reproductive System Neoplasm | Primary Peritoneal Carcinoma | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer AJCC v7 | Stage IIIC Uterine Corpus Cancer AJCC v7 | Stage IVA... and other conditions

United States, Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Branch Retinal Vein Occlusion (BRVO) (COMRADE-B)

Macular Edema | Visual Impairment | Branch Retinal Vein Occlusion

Germany, United Kingdom, Hungary, Poland, Czech Republic
University Hospital Southampton NHS Foundation...
Liverpool Heart and Chest Hospital NHS Foundation Trust

Unknown

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes? (RIPCORD 2)

Chest Pain | Acute Coronary Syndrome | Stable Angina | Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom

Clinical Trials on Nervous System Lyme Borreliosis in United States

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

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Sponsor/Collaborators

Locations