Clinical Trials on Neurotoxicity in United Kingdom

Total 106 results

NHS Greater Glasgow and Clyde

Recruiting

Biomarkers for Chemotherapy Associated Neurotoxicity (BioCAN)

Chemotherapy-Related Cognitive Impairment

United Kingdom
University College, London

Completed

Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma

Lymphoma | Neurotoxicity

United Kingdom
University College, London
Cancer Research UK

Completed

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Lymphoma | Mucositis | Neurotoxicity | Chemotherapeutic Agent Toxicity

United Kingdom
Baylor College of Medicine

Completed

Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years

Seizures | Development Delay | Anesthetic Neurotoxicity

United States
M.D. Anderson Cancer Center

Not yet recruiting

A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity

Neurotoxicity

United States
University of Medicine and Dentistry of New Jersey

Terminated

A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity

Neurotoxicity Syndromes

United States
Gerald Higa, PharmD.

Terminated

Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathway

Neurotoxicity

United States
Medical University of South Carolina
Veloxis Pharmaceuticals

Completed

Envarsus Neurotoxicity Burden in Liver Transplant Patients

Neurotoxicity | Liver Transplant; Complications

United States
Vanderbilt University Medical Center

Completed

Effect of Antibiotic Choice On ReNal Outcomes (ACORN) (ACORN)

Sepsis | AKI | Neurotoxicity

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
University at Buffalo
Cubist Pharmaceuticals LLC

Completed

Vancomycin-Associated Nephrotoxicity

Nephrotoxicity

United States
University of Colorado, Denver
Memorial Sloan Kettering Cancer Center; National Institute of General Medical... and other collaborators

Recruiting

Cisplatin Disposition and Kidney Injury

Nephrotoxicity

United States
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

Lymphoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
Murdoch Childrens Research Institute
Baylor College of Medicine; Children's Hospital of Philadelphia; Boston Children... and other collaborators

Active, not recruiting

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics (TREX)

Child Development | Anesthesia | Neurotoxicity

United States, Australia, Italy, Spain
Sanofi

Completed

Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.

Colorectal Neoplasms | Colorectal Carcinoma | Metastases

United States, Canada, Brazil, Poland, Australia, Germany, Italy, Portugal, Spain, Argentina, Hungary, United Kingdom, Chile
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
Jazz Pharmaceuticals

Terminated

A Safety and Efficacy Study of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity

Neurotoxicity Syndromes | DLBCL

United States
Dartmouth-Hitchcock Medical Center
Disarm Therapeutics

Completed

Biomarkers in Chemotherapy-Induced Peripheral Neurotoxicity (CIPN)

CIPN - Chemotherapy-Induced Peripheral Neuropathy

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
National Institute of Nursing Research (NINR)

Terminated

Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage

Cancer | Neurotoxicity | Peripheral Neuropathic Pain

United States
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Completed

Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimen

HIV | Neurotoxicity | HIV-associated Neurocognitive Disorder

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy

Pain | Neurotoxicity

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Colorectal Cancer | Neurotoxicity | Neuropathy | Chemotherapeutic Agent Toxicity

United States, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201

Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children

United States, Canada
National Cancer Institute (NCI)

Suspended

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

Lymphoma | Leukemia

United States
Thomas Jefferson University
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation

Neurotoxicity | Renal Toxicity | Side Effects of Calcineurin Inhibitors | Hepatic Fibrosis on Biopsy | Post Transplant Diabetes

United States
Gary Morrow
National Cancer Institute (NCI)

Completed

Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Peripheral Neuropathy

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
University of South Florida
National Cancer Institute (NCI)

Terminated

Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression

Depression | Unspecified Childhood Solid Tumor, Protocol Specific | Neurotoxicity

United States
National Cancer Institute (NCI)
Children's Oncology Group

Completed

Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate

Unspecified Childhood Solid Tumor, Protocol Specific | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States, Canada, Australia, Switzerland
University of California, San Diego
Center for Medicinal Cannabis Research

Recruiting

Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

HIV | Cannabis Use

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Acute Pain Caused by Paclitaxel in Patients With Cancer

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Chemotherapeutic Agent Toxicity

United States
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Cognitive/Functional Effects

United States, Canada
Northwestern University

Terminated

D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain

Pain | Breast Cancer | Neurotoxicity

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Peripheral Neuropathy

United States
HealthPartners Institute

Terminated

L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer

Breast Cancer | Neurotoxicity | Chemotherapeutic Agent Toxicity

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
Jack Khouri

Not yet recruiting

Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM

Multiple Myeloma | Refractory Multiple Myeloma | Cytokine Release Syndrome | Immune Effector Cell Associated Neurotoxicity Syndrome

United States
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors

Primary Central Nervous System Lymphoma (PCNSL)

United States, Germany
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); North Central Cancer Treatment Group

Completed

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery

Colorectal Cancer | Neurotoxicity

United States
Northside Hospital, Inc.

Recruiting

Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer

Breast Cancer | Neurotoxicity

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases

Solid Tumor | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects

United States
Indiana University

Completed

Switch From Calcineurin Inhibitor to Belatacept in Pancreas Transplant Recipients

Nephrotoxicity

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo

Breast Cancer | Fatigue | Neurotoxicity | Neuropathy | Chemotherapeutic Agent Toxicity

United States

Clinical Trials on Neurotoxicity in United Kingdom

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