Clinical Trials on Newly Diagnosed Carcinoma of Unknown Primary

Total 900 results

Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Bladder or Kidney Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Following Surgery in Treating Patients With Advanced Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

Primary Peritoneal Cavity Cancer | Carcinoma of the Appendix

United States
Threshold Pharmaceuticals
M.D. Anderson Cancer Center

Unknown

Immunotherapy Study of Evofosfamide in Combination With Ipilimumab

Melanoma | Pancreatic Cancer | Prostate Cancer | Squamous Cell Carcinoma of the Head and Neck

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

BGJ398 in Non-Muscle-Invasive Urothelial Carcinoma of the Bladder

Bladder Cancer | Non-Muscle-Invasive Urothelial Carcinoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
University Health Network, Toronto

Recruiting

Genomic Investigation of Unusual Responders (GENIUS)

Cancer | Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Melanoma (Skin) | Genitourinary Cancer | Gynecological Cancer | Rare Cancer | Carcinoma of Unknown Primary | Pancreatobiliary Gastrointestinal Cancer | Upper Aerodigestive Tract Cancer

Canada
Noah Hahn, M.D.
AstraZeneca; Hoosier Cancer Research Network

Recruiting

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder (ADAPT-BLADDER)

Bladder Cancer | Urothelial Carcinoma

United States
Pfizer

Completed

A Study to Describe the Kidney Cancer Patient Population Treatment, and Results in the Hospital District of Southwest Finland.

Kidney Cancer | Kidney Neoplasms | Renal Cell Carcinoma | Renal Cancer | Renal Cell Cancer | Cancer of the Kidney | Cancer of Kidney

Finland
Eli Lilly and Company

Completed

A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cancer of Head and Neck

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb

Active, not recruiting

Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder

Bladder Cancer | Urothelial Carcinoma

United States
Centre Georges Francois Leclerc

Recruiting

Study Evaluating the Efficacy and the Tolerance of Pelvic-prostatic Hypo-fractionated Radiotherapy Followed by Boost in Patients With Prostate Adenocarcinoma Adverse Intermediate Risk or High Localized Risk (SHORT)

To Evaluate the Rate of Digestive and Urinary Toxicity

France
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI)

Completed

R115777 in Treating Patients With Advanced Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
Preben Kjolhede, MD, professor
Linkoeping University; Ostergotland County Council, Sweden; Medical Research... and other collaborators

Completed

Lymphedema After Primary Surgery for Endometrial Cancer (LASEC)

Hysterectomy | Lymphadenectomy | Carcinoma of the Endometrium

Sweden
Mansoura University

Completed

Value of Immediate Post-operative Intravesical Epirubicin in Intermediate&High Risk Non Muscle Invasive Bladder Cancer (NMIBCIVT)

Carcinoma of Urinary Bladder, Superficial

Egypt
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Completed

Combined Use of BCG and Interferon Alpha in Bladder Cancer

Carcinoma of Urinary Bladder, Superficial

Singapore
Lei Li

Unknown

Non-coding RNA in the Exosome of the Epithelia Ovarian Cancer

Ovarian Cancer | High Grade Serous Carcinoma | Prognosis | Early Diagnosis | Exosomes

China
Amgen

Unknown

Combination Chemotherapy Plus Filgrastim in Treating Patients With Locally Recurrent or Advanced Urothelium Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
Institut Curie

Completed

Sunitinib as Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Transitional Cell Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

France
Charite University, Berlin, Germany

Completed

An Algorithm for Intra-operative Goal-directed Haemodynamic Management in Non-cardiac Surgery (ERAS_feasi)

Fracture of Surgical Neck of Humerus | Colonic Tumor | Stage IIIB Ovarian Carcinoma | Neoplasm of Head of Pancreas

Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Gemcitabine, Paclitaxel, and Cisplatin in Treating Patients With Advanced Cancer of the Urothelium

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States
National Cancer Institute (NCI)

Active, not recruiting

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Sezary Syndrome | Refractory T-Cell Non-Hodgkin Lymphoma | Merkel Cell Carcinoma | Anaplastic Large Cell Lymphoma, ALK-Positive | Extramammary Paget Disease | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin... and other conditions

United States
M.D. Anderson Cancer Center

Active, not recruiting

Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix

Cervical Cancer | Cervix Cancer | Carcinomas

United States
Mansoura University

Active, not recruiting

Can VI-RADS/ADC Accurately Stage Bladder Cancer??

Bladder Cancer | Diagnoses Disease | Bladder Disease | Bladder Urothelial Carcinoma | Bladder Neoplasm | MRI Contrast Media Adverse Reaction | Bladder Cancer Stage

Egypt
Shattuck Labs, Inc.

Completed

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Melanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditions

United States, Canada, Belgium, Spain
National Cancer Institute (NCI)

Suspended

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

Endometrial Cancer | Endometrial Carcinoma | Cancer of Endometrium | Carcinoma of Endometrium

United States
Tata Medical Center

Completed

Short Course Radiotherapy for Localized Prostate Cancer (SHORT)

Adenocarcinoma of Prostate

India
University of Rochester

Completed

Devel. and Eval. of an Active Surveillance Decision Aid for Men With Low or Intermediate Grade Prostate Cancer

Adenocarcinoma of Prostate

United States
National Institute of Oncology, Hungary

Unknown

HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer. (PROMOBRA)

Adenocarcinoma of Prostate

Hungary
Celldex Therapeutics
Bristol-Myers Squibb

Completed

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Ovarian Carcinoma-Enrollment Completed | Colorectal Cancer (CRC)-Enrollment Completed | Renal Cell Carcinoma (RCC) (Phase ll Only) | Glioblastoma (GBM) (Phase ll Only)-Enrollment Completed

United States
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Barretos Cancer Hospital
M.D. Anderson Cancer Center; National Institutes of Health (NIH); William Marsh...

Completed

HRME: Screening for Cervical Cancer and Its Precursors in Low-Resource Settings (HRME-UH2)

Cervical Intraepithelial Neoplasia | Cancer Prevention | Neoplasia of the Uterine Cervix
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
University of Southern California
National Cancer Institute (NCI); GlaxoSmithKline

Terminated

Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in Bladder

Recurrent Bladder Cancer | Stage III Bladder Cancer | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary | Recurrent Oral Cavity... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
University Health Network, Toronto

Completed

Intensity Modulated Radiation Therapy (IMRT) Pelvic Nodes Prostate

Adenocarcinoma of the Prostate

Canada
Dendreon
PRA Health Sciences

Active, not recruiting

Open- Label Trial of Sipuleucel-T Administered to Active Surveillance Patients for Newly Diagnosed Prostate Cancer (ProVent)

Adenocarcinoma of the Prostate

United States
Fundacao Champalimaud

Unknown

Hypofractionated Image-Guided Radiotherapy (IGRT) With Organ Motion Mitigation and Urethral Sparing for Prostate Cancer

Adenocarcinoma of the Prostate

Portugal
Centre Hospitalier Universitaire Vaudois

Terminated

Active Surveillance of 2 Groups of Patients With Localized Prostate Cancer

Adenocarcinoma of the Prostate

Switzerland
University of Washington
National Cancer Institute (NCI)

Completed

Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Recurrent Prostate Carcinoma | Castration Levels of Testosterone | Stage IV Prostate Adenocarcinoma

United States
Rush University Medical Center

Withdrawn

Low-moderate Intensity Pedaling During Immunotherapy Administration

Immunotherapy | Cancer of Skin | Exercise, Aerobic | Cancer of Kidney | Cancer of Bladder

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Cancer Immunotherapy Trials Network

Completed

CYT107 After Vaccine Treatment (Provenge®) in Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer | Castration Levels of Testosterone

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Pfizer

Completed

Dacomitinib (PF-00299804) in Advanced/Metastatic Squamous Cell Carcinoma of the Penis (HER-Uro01)

Carcinoma, Squamous Cell | Penile Neoplasms

Italy
National Cancer Institute (NCI)

Not yet recruiting

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

Adenocarcinoma of the Bladder | Squamous Cell Carcinoma of the Bladder | Testicular Germ Cell Tumors

United States
National Cancer Institute (NCI)

Completed

Pazopanib in Treating Patients With Metastatic Urothelial Cancer

Recurrent Bladder Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Stage IV Bladder Cancer | Transitional Cell Carcinoma of the Bladder | Distal Urethral Cancer | Proximal Urethral Cancer | Recurrent Urethral Cancer | Urethral Cancer Associated With Invasive Bladder Cancer

United States, China, Korea, Republic of
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States

Clinical Trials on Newly Diagnosed Carcinoma of Unknown Primary

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