Clinical Trials on Niemann-Pick Disease, Type C1 in Brazil

Total 984 results

Brooklyn ImmunoTherapeutics, LLC

Completed

IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity (INSPIRE)

Squamous Cell Carcinoma of the Oral Cavity

United States, Brazil, United Kingdom, Canada
Seelos Therapeutics, Inc.

Terminated

STRIDES - a Clinical Research Study of an Investigational New Drug to Treat Spinocerebellar Ataxia (STRIDES)

Spinocerebellar Ataxia Type 3

United States, Spain, Korea, Republic of, Australia, United Kingdom, Brazil, Germany, Portugal
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.

Sarcoma

Spain, Belgium, Canada, Czechia, France, Brazil, United Kingdom, Israel, Italy, Russian Federation, Netherlands, Poland, Chile, Germany
BioMarin Pharmaceutical

Terminated

A Prospective, Noninterventional, Observational Study of Late-Onset Pompe Disease

Late-onset Pompe Patients Untreated or Treated With rhGAA

Spain, Slovenia, Serbia, Korea, Republic of, Greece, Australia, Singapore, Brazil, Canada, Taiwan, Ireland, Poland, Romania
Actelion

Completed

Clinical Study to Evaluate the Long Term Efficacy, Safety and Tolerability of Miglustat in Patients With Stable Type 1 Gaucher Disease

Gaucher Disease Type 1

United States, Taiwan, Canada, Spain, Australia, France, Brazil, Hungary, Czechia, Germany, Italy, Netherlands, United Kingdom
Genentech, Inc.
Chugai Pharmaceutical Co.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Gastric Cancer | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma

Korea, Republic of, Spain, Japan, New Zealand, Australia, United States, Italy, Brazil
Eli Lilly and Company

Completed

A Study of LY900014 in Participants With Type 1 Diabetes (PRONTO-T1D)

Type 1 Diabetes Mellitus

Italy, Japan, United States, Puerto Rico, Spain, Taiwan, Mexico, Austria, Germany, Poland, New Zealand, Romania, Russian Federation, Argentina, India, Sweden, Slovakia, Australia, Brazil, Greece
Novartis Pharmaceuticals

Completed

A Phase III Randomized, Double Blind, Placebo Controlled Multi-center Study of Panobinostat for Maintenance of Response in Patients With Hodgkin's Lymphoma (HL) (PATH)

Hodgkin's Lymphoma

United States, Belgium, Germany, Canada, Singapore, Netherlands, France, Australia, Russian Federation, Israel, Brazil, Italy, New Zealand, Poland
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

Metastatic Melanoma

France, Italy, Spain, Brazil, Latvia, Germany, Hungary, Switzerland
Sanofi

Completed

A Study of AVE8062 in Advanced-stage Soft Tissue Sarcoma After Failure of Anthracycline and Ifosfamide Chemotherapies

Sarcoma

Belgium, Hungary, United States, Brazil, France, India, Italy, Serbia, Spain, United Kingdom
Mannkind Corporation

Completed

A 2-Month Safety Follow-Up Trial

Type 1 Diabetes | Type 2 Diabetes

United States, Brazil, Canada, Russian Federation
Sanofi

Completed

Docetaxel in Combination With Cisplatin-5-fluorouracil for the Induction Treatment of Nasopharyngeal Carcinoma in Children and Adolescents

Carcinoma | Nasopharyngeal Neoplasms

France, Korea, Republic of, Turkey, Algeria, Brazil, China, India, Indonesia, Italy, Mexico, Morocco, Philippines, Thailand, Tunisia
Hoffmann-La Roche

Recruiting

A Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma

Melanoma

Brazil, Czechia, Spain, Turkey, New Zealand, Canada, Australia, Poland, Slovakia, Greece
Bristol-Myers Squibb
Merck Sharp & Dohme LLC

Completed

Study of Muraglitazar Versus Pioglitazone in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, Argentina, Canada, Mexico, Peru, Taiwan, Australia, Philippines, Thailand, Brazil, Chile, India, Russian Federation, Ukraine
AstraZeneca

Completed

Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients

Melanoma

Sweden, United States, Brazil, Czech Republic, France, Spain, United Kingdom, Germany, Norway, Hungary, Netherlands, Switzerland
Lexicon Pharmaceuticals
Sanofi

Completed

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control (SOTA-CKD3)

Type 2 Diabetes Mellitus | Chronic Kidney Disease Stage 3

United States, Argentina, Brazil, Canada, Colombia, Germany, Hungary, Israel, Italy, Mexico, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine
McMaster University
Hamilton Academic Health Sciences Organization

Recruiting

Surveillance AFter Extremity Tumor surgerY (SAFETY)

Soft Tissue Sarcoma | Lung Metastases

United States, Canada, Netherlands, Brazil, Argentina, Australia, Austria, Italy
Eli Lilly and Company

Completed

A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD) (AWARD-7)

Type 2 Diabetes | Chronic Kidney Disease

Mexico, United States, Hungary, Ukraine, Brazil, Spain, Romania, South Africa, Poland
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4)

Type 2 Diabetes Mellitus

Russian Federation, United States, Puerto Rico, Australia, Taiwan, Israel, Spain, Canada, Greece, Argentina, Poland, Romania, Mexico, Slovakia, Brazil
Fondazione Italiana Linfomi ONLUS

Completed

Prognosis Of Patients With Aggressive B-Cell Lymphoma, Treated With Rituximab+Anthracycline Regimen (ProDLBCL)

B-Cell Lymphomas

Italy, Brazil
Hoffmann-La Roche

Completed

An Open-Label, Single Arm Study of Obinutuzumab Short Duration Infusion in Patients With Previously Untreated Advanced Follicular Lymphoma

Advanced Follicular Lymphoma

Germany, Brazil, United Kingdom, Spain, Japan, United States, Netherlands
Bristol-Myers Squibb

Terminated

An Investigational Immuno-therapy Study of Ulocuplumab in Combination With Low Dose Cytarabine in Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia

Taiwan, United States, Brazil, Japan, Italy, Korea, Republic of, Canada, China, Israel, Romania
Merck Sharp & Dohme LLC

Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Melanoma | Lymphoma | Solid Tumor | Classical Hodgkin Lymphoma | Microsatellite-instability-high Solid Tumor

France, Germany, Italy, Netherlands, Sweden, United Kingdom, Brazil, Israel, Korea, Republic of, United States
Sanofi

Completed

Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus (EDITION JUNIOR)

Type 1 Diabetes Mellitus

France, Czechia, Chile, Israel, Spain, Hungary, Mexico, Serbia, Japan, Canada, Brazil, Sweden, Denmark, Argentina, United States, Bulgaria, Germany, Italy, Latvia, North Macedonia, Poland, Romania, Russian Federation, United Kingdom
AstraZeneca

Completed

Study to Evaluate Safety and Efficacy of Dapagliflozin and Saxagliptin in Patients With Type 2 Diabetes Mellitus (T2DM) Aged 10 to Below 18 Years Old

Diabetes Mellitus, Type 2

United States, Thailand, United Kingdom, Malaysia, New Zealand, Taiwan, Turkey, Canada, Mexico, Israel, India, Argentina, Brazil, Russian Federation, Australia, Korea, Republic of, Italy, Philippines, Colombia, Poland, Chile, Finland and more
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.

Diabetes Mellitus Type 2

United States, France, Canada, Mexico, Guatemala, Germany, Brazil, Puerto Rico, Costa Rica
AstraZeneca

Completed

Randomised Study to Compare the Efficacy of AZD6244 vs TMZ

Melanoma

United States, Australia, Brazil, United Kingdom, Argentina, Austria, Canada, Denmark, France, Switzerland
Latin American Cooperative Oncology Group
Ipsen

Recruiting

Clinical-pathological Characterization and Outcomes of Renal Cell Carcinoma in Latin American

Kidney Neoplasms

Brazil
Royal Marsden NHS Foundation Trust

Unknown

Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Gastrointestinal Neoplasms | Digestive System Neoplasms | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal... and other conditions

Canada, United Kingdom, Brazil, Cyprus
AstraZeneca

Completed

DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings (DISCOVER)

Type 2 Diabetes Mellitus

Brazil, Italy, Korea, Republic of, Mexico, Poland, Russian Federation, South Africa, Spain, Turkey, China, Netherlands, Argentina, Austria, Czechia, United Arab Emirates, Taiwan, India, Egypt, Saudi Arabia, Lebanon, Indonesia, Col... and more
Novartis Pharmaceuticals

Terminated

Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 Mg (MACS0375)

Gastrointestinal Stromal Tumors

China, Argentina, Russian Federation, Thailand, Korea, Republic of, Brazil, Canada, Venezuela, Mexico
Novartis Pharmaceuticals

Completed

Phase II Study of Oral Panobinostat in Adult Participants With Relapsed/Refractory Classical Hodgkin's Lymphoma

Classical Hodgkin's Lymphoma

Spain, France, Belgium, Italy, Israel, Germany, United States, Australia, Brazil, Singapore, Malaysia, New Zealand, United Kingdom
Ionis Pharmaceuticals, Inc.

Recruiting

FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)

Amyotrophic Lateral Sclerosis

United States, Germany, Netherlands, Spain, Korea, Republic of, Canada, Switzerland, Belgium, Italy, United Kingdom, Ireland, Sweden, Taiwan, Brazil
AstraZeneca

Terminated

GALLANT 14 Tesaglitazar vs. Metformin and Fenofibrate

Type 2 Diabetes

Brazil, France, Russian Federation, South Africa, Germany, Malaysia, Finland, Norway, Hong Kong, Canada, Hungary, Portugal, Taiwan, India, Philippines, Switzerland, Indonesia, Singapore
PTC Therapeutics

Active, not recruiting

A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS) (SUNRISELMS)

Leiomyosarcoma

United States, United Kingdom, France, Italy, Netherlands, Spain, Australia, Canada, Brazil, Germany, Hungary, Poland
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Heart Failure | Type 2 Diabetes Mellitus

Belgium, Canada, Israel, Spain, Germany, Argentina, Chile, Hungary, Korea, Republic of, Latvia, Lithuania, Russian Federation, Sweden, Romania, Poland, Brazil, Denmark, United States, Australia, Austria, Czechia, Finland, France, Greece, Ita... and more
Genzyme, a Sanofi Company

Completed

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease (COMET)

Glycogen Storage Disease Type II;Pompe's Disease

Czechia, Taiwan, Belgium, Germany, Korea, Republic of, United States, Argentina, Australia, Austria, Brazil, Canada, Denmark, France, Hungary, Italy, Japan, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Switzerland, Turk... and more
Taiho Oncology, Inc.

Recruiting

Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement (FOENIX-CCA4)

Advanced Cholangiocarcinoma | FGFR2 Fusions | Gene Rearrangement

United States, Korea, Republic of, Spain, Japan, Portugal, Italy, China, Argentina, Brazil, Poland, Australia
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin (SURPASS-6)

Type 2 Diabetes

United States, Puerto Rico, Spain, Germany, Argentina, Brazil, Turkey, Hungary, Italy, Russian Federation, Slovakia, Belgium, Czechia, Greece, Mexico, Romania
Novo Nordisk A/S

Completed

Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin (SIT2MIX)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of, India, Malaysia, Turkey, Argentina, Greece, Australia, Portugal, Thailand, Brazil
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Pioglitazone in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

France, United States, Mexico, United Kingdom, Spain, Canada, New Zealand, Thailand, Russian Federation, Brazil, Germany, Australia, Poland, Slovakia, Peru, Ukraine, South Africa, Costa Rica, Puerto Rico
Fondazione Italiana Linfomi - ETS

Active, not recruiting

Indolent Non Follicular Lymphomas Prognostic Project

Indolent B-Cell Lymphomas

France, Italy, Brazil, Austria, Portugal, Ukraine
Eli Lilly and Company

Completed

A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-2)

Diabetes | Type 2 Diabetes

United States, China, Germany, Mexico, Brazil, Canada, Japan, Korea, Republic of, Puerto Rico, Czechia, Greece
Centre hospitalier de l'Université de Montréal...
Centre Hospitalier Régional et Universitaire de Brest

Recruiting

Treatment of Brain AVMs (TOBAS) Study (TOBAS)

Arteriovenous Malformations | Unruptured Brain Arteriovenous Malformation | Ruptured Brain Arteriovenous Malformation | AVM | BAVM

France, United States, Canada, Brazil, Chile, Colombia
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes (SURPASS-2)

Type 2 Diabetes

United States, Puerto Rico, Australia, United Kingdom, Mexico, Argentina, Brazil, Israel, Canada
Therapeutic Advances in Childhood Leukemia Consortium

Completed

Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

United States, Australia, Canada, Brazil
Mannkind Corporation

Completed

Clinical Trial Evaluating Technosphere® Insulin Versus Insulin Aspart in Subjects With Type 1 Diabetes Mellitus Over a 24-week Treatment Period

Type 1 Diabetes Mellitus

United States, Brazil, Russian Federation, Ukraine
Novo Nordisk A/S

Withdrawn

Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes

Diabetes Mellitus, Type 2

Thailand, Malaysia, Poland, India, Hungary, Mexico, Brazil, United States, Croatia, Romania, Bulgaria, Greece, Serbia
Novo Nordisk A/S

Completed

Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT) (SUSTAIN)

Diabetes Mellitus, Type 2 | Diabetes

Taiwan, Korea, Republic of, South Africa, Hong Kong, Brazil, China, Ukraine
Novo Nordisk A/S

Recruiting

A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor (REIMAGINE 2)

Type 2 Diabetes Mellitus

Korea, Republic of, United States, Hungary, Serbia, Spain, China, Australia, Finland, United Kingdom, Italy, Denmark, Canada, Taiwan, Poland, Germany, Sweden, South Africa, India, Argentina, Brazil, Bulgaria, Japan, Mexico, Turkey, Greece, Colomb... and more

Clinical Trials on Niemann-Pick Disease, Type C1 in Brazil

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ethiopia

Conditions

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Drug Interventions

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