Clinical Trials on Niemann-Pick Disease in Germany

Total 21648 results

Cyclo Therapeutics, Inc.

Active, not recruiting

Phase 3 Study to Evaluate Intravenous Trappsol(R) Cyclo(TM) in Pediatric and Adult Patients With Niemann-Pick Disease Type C1 (TransportNPC)

Niemann-Pick Disease, Type C1

United States, Taiwan, United Kingdom, Israel, Spain, Brazil, Italy, Australia, Turkey, Saudi Arabia, Argentina, Poland, Germany
IntraBio Inc

Completed

N-Acetyl-L-Leucine for Niemann-Pick Disease, Type C (NPC)

Niemann-Pick Disease, Type C

United States, United Kingdom, Germany, Slovakia, Spain
Mandos LLC

Completed

VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, France, New Zealand, Singapore, Spain, Turkey
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Niemann Pick Type C Disease (BioNPC) (BioNPC)

Niemann-Pick Disease, Type C | Niemann-Pick Disease

Germany, India, Sri Lanka
KemPharm Denmark A/S

Completed

A Prospective Non-therapeutic Study in Patients Diagnosed With Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

Spain, France, United Kingdom, Switzerland, Denmark, Poland, Italy, Germany
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
Mandos LLC

Terminated

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Turkey, Switzerland, Germany, New Zealand, Singapore, France
ZevraDenmark

Active, not recruiting

Arimoclomol Prospective Study in Participants Diagnosed With Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Spain, United Kingdom, Denmark, France, Germany, Italy, Poland, Switzerland
Genzyme, a Sanofi Company

Completed

A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

Sphingomyelin Lipidosis

United States, Belgium, Brazil, France, Germany, Italy, United Kingdom
Genzyme, a Sanofi Company

Completed

Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency (ASCEND-Peds)

Sphingomyelin Lipidosis

Brazil, France, Italy, United States, Germany, United Kingdom
Genzyme, a Sanofi Company

Completed

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency (ASCEND)

Sphingomyelin Lipidosis

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Chile, France, Germany, Italy, Japan, Netherlands, Portugal, Spain, Tunisia, Turkey, United Kingdom
Sanofi

Completed

A Prospective and Retrospective Cohort Study in Patients With Chronic Forms of Acid Sphingomyelinase Deficiency (ASMD)

Sphingomyelin Lipidosis

Italy, Czechia, Belgium, France, Portugal, Turkey, United States, Argentina, Brazil, Chile, Germany, Romania, Spain
Jena University Hospital

Completed

SHERLOCK 3CG vs. Fluoroscopy in Implantation of PICC-Line (3CG)

Patients With PICC-Line

Germany
Novartis Vaccines

Completed

An Extension Study to Determine the Persistence of Tick-borne Encephalitis (TBE)-Specific Antibody Responses Among Children and Adolescents Previously Immunized Against TBE

Tick Borne Encephalitis (TBE)

Germany
Novartis
Novartis Vaccines

Completed

Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults

Encephalitis, Tick-Borne

Germany
Pfizer

Completed

Tick-Borne Encephalitis (TBE) Seropersistence After First Booster and Response to a Second Booster in Children, Adolescents and Young Adults (Follow-Up to Study 700401)

Encephalitis, Tick-Borne

Austria, Germany, Poland
Novartis
Novartis Vaccines

Completed

Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children

Encephalitis, Tick-Borne

Germany
Otto-von-Guericke University Magdeburg
University Hospital Regensburg; University of Regensburg

Completed

ICU Follow-up After Prolonged Intensive Care Stay (PINA)

Critical Illness | Post Intensive Care Syndrome | PICS

Germany
Pfizer

Completed

Safety Study of FSME-IMMUN NEW in Healthy Children and Adolescents Aged 1 to 15 Years

Tick-borne Encephalitis

Austria, Germany, Poland
Integra LifeSciences Corporation

Completed

Duragen® Secure Post Marketing Clinical Follow-up (PMCF)

Surgery | Dura Mater Nick Cut or Tear

France, Spain, United Kingdom, Germany
Guidant Corporation

Completed

Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA Class

Atrial Fibrillation | Heart Block | Bradycardia | Sick Sinus Syndrome

Germany
Klinikum Nürnberg

Unknown

RV Septal Versus Minimized RV Pacing in Sick Sinus Syndrome (VOTE)

Sick Sinus Syndrome

Germany
Pfizer

Completed

FSME IMMUN NEW Follow-up to Study 199 in Children Aged 1 to 6 Years

Encephalitis, Tick-borne

Austria, Germany
Pfizer

Completed

Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 6 to 16 Years.

Tick-borne Encephalitis

Germany
Pfizer

Completed

Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 1 to 6 Years.

Tick-borne Encephalitis

Austria, Germany
Ruhr University of Bochum
Wissenschaftskommission des Universitaetsklinikums Bergmannsheil; Private Sponsor...

Unknown

Approach to a Quantitative Follow-up of Non-thyroidal Illness Syndrome (AQUA FONTIS)

Euthyroid Sick Syndromes | Non-thyroidal Illness Syndrome | Low T3 Syndrome | TACITUS

Germany
Novartis
Novartis Vaccines

Completed

Evaluation of Long-Term Immunogenicity in Children and Adolescents Boosted With a New Pediatric TBE Vaccine After Five Years

Encephalitis, Tick-Borne

Germany
Pfizer

Completed

TBE Antibody Persistence and Booster Vaccination Study in Children and Adolescents (Follow-up to Study 209)

Encephalitis, Tick-Borne

Germany, Austria, Poland
Pfizer

Completed

FSME IMMUN NEW Follow-up to Study 205 in Children Aged 6 to 16 Years

Encephalitis, Tick-borne

Germany
Deutsches Herzzentrum Muenchen
Medtronic; Klinikum Bamberg; Krankenhaus Peißenberg

Completed

Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing (ADVANTAGE)

Pacemaker Implantation for Sinus Node Disease

Germany
Medtronic BRC
Vitatron GmbH

Unknown

Mode Evaluation in Sick Sinus Syndrome Trial (MODEST)

Sick Sinus Syndrome

Germany
Technical University of Munich
University of Melbourne

Completed

RHAPSODY-plus: Online Counseling for Family Caregivers of Patients With Young Onset Dementia (RHAPSODY-plus)

Frontotemporal Dementia | Early Onset Alzheimer Disease

Germany
University Hospital, Bonn

Completed

Auditory Beat Stimulation and Behavioural Variant of Frontotemporal Dementia

Anxiety | bvFTD

Germany
Medtronic BRC

Unknown

Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.

Bradycardia; Sick Sinus Syndrome, AV Block

Germany, Denmark, Netherlands, Austria, Czech Republic, United Kingdom, Sweden, Finland, Italy, Russian Federation, Switzerland
Baxter Healthcare Corporation

Completed

Hemopatch Performance Evaluation: A Prospective Observational Registry

Air Leakage | Dura Mater Nick Cut or Tear | Hemostatis | Body Fluid Leakage

Germany, Spain, Czechia, Italy, Austria
Axon Neuroscience SE

Unknown

A 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive Aphasia (AIDA)

Primary Progressive Nonfluent Aphasia

Germany
Medtronic BRC
Vitatron GmbH

Completed

Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation

Sick Sinus Syndrome

Germany
Baxalta now part of Shire
Baxter Innovations GmbH

Completed

Phase 1/2 Lyme Vaccine Study

Prophylaxis of Lyme Borreliosis

Germany, Austria
Lyme Diagnostics Ltd.
Pharmahungary Group

Completed

Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis

Lyme Borreliosis

Austria, Czechia, Germany, Hungary, Poland, Slovakia
U.S. Army Medical Research and Development Command
Bausch Health Americas, Inc.

Withdrawn

Treatment of Viral Hemorrhagic Fevers With Intravenous Ribavirin in Military Treatment Facilities

Crimean-Congo Hemorrhagic Fever | Lassa Fever

Germany
Pfizer

Completed

Immunogenicity and Safety Study of a Vaccine Against Lyme Borreliosis, in Healthy Adults Aged 18 to 65 Years. Randomized, Controlled, Observer-blind Phase 2 Study.

Lyme Borreliosis

United States, Germany, Belgium
Karoline Krause
Roche Pharma AG

Completed

Tocilizumab in Patients With Schnitzler's Syndrome (TOCISCH)

Schnitzler's Syndrome

Germany
University of Rostock
German Center for Neurodegenerative Diseases (DZNE); Fraunhofer Institute

Completed

SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia (SAIN_UMR)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Frontotemporal

Germany
Alector Inc.

Active, not recruiting

A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

Frontotemporal Dementia

Canada, United States, Germany, United Kingdom, Italy, Netherlands
Boston Scientific Corporation

Completed

Ingenio Device Algorithm Study (IVORY)

Heart Failure | AV Block | Sinus Node Disease

Denmark, United Kingdom, Spain, Hong Kong, Netherlands, Sweden, Malaysia, Austria, Belgium, France, Germany, Italy
CENTOGENE GmbH Rostock

Active, not recruiting

Epidemiological Study in FRONtoTemporal Dementia (EFRONT)

Frontotemporal Dementia

Italy, Spain, Belgium, Turkey, Portugal, Germany, Greece
Pfizer
Valneva Austria GmbH

Active, not recruiting

An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15) (VALOR)

Lyme Disease

United States, Finland, Canada, Poland, Sweden, Germany, Netherlands
Boston Scientific Corporation

Completed

Safety and Performance Study of the INGEVITY Lead

Bradycardia | Sinus Node Dysfunction

United States, Belgium, Germany, Canada, Spain, Sweden, Italy, Malaysia, Denmark, Australia, Austria, United Kingdom, Hong Kong, France, Portugal, Thailand
Transposon Therapeutics, Inc.

Active, not recruiting

A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD

Amyotrophic Lateral Sclerosis | Frontotemporal Dementia

Spain, United States, Belgium, France, Germany
LivaNova

Completed

Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease

Sinus Node Dysfunction | Brady Tachy Syndrome

United States, France, Belgium, Germany, United Kingdom, Italy, Monaco, Spain

Clinical Trials on Niemann-Pick Disease in Germany

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