Clinical Trials on Non-small- Cell Lung Cancer (NSCLC) in Italy

Total 679 results

EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Tuvusertib (M1774) in Combination With Cemiplimab in Participants With Non-Squamous NSCLC (DDRiver NSCLC 322)

Non-Small Cell Lung Cancer

Korea, Republic of, United States, Japan, Spain, Italy, Belgium, France, Germany
Bristol-Myers Squibb

Recruiting

A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

Netherlands, Belgium, United States, Australia, Greece, Italy, Canada, Japan, Poland, Romania, Spain
Fondazione per la Medicina Personalizzata

Active, not recruiting

The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy (ROME)

Breast Cancer | Non Small Cell Lung Cancer | Gastrointestinal Cancer | Other Cancer

Italy
AstraZeneca

Active, not recruiting

AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy. (ADAURA)

Stage IB-IIIA Non-small Cell Lung Carcinoma

United States, Italy, Netherlands, Belgium, Canada, Poland, Romania, Taiwan, Thailand, Vietnam, France, Brazil, Hungary, Japan, Russian Federation, Turkey, China, Korea, Republic of, Germany, Hong Kong, Spain, Australia, Israel, Ukraine, Swed...
Novartis Pharmaceuticals

Terminated

A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma

Melanoma | Non-Small Cell Lung Cancer

Italy, Australia, Belgium, Germany, Spain, Korea, Republic of, Israel, France, United States, Sweden, Poland
Eli Lilly and Company

Terminated

Chemotherapy and Radiotherapy to Treat Patients With Limited Stage of Small Cell Lung Cancer (SCLC)

Small Cell Lung Cancer

Italy, Poland, United Kingdom, Spain
Istituto Scientifico Romagnolo per lo Studio e...
Pierre Fabre Laboratories

Terminated

Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression (HighTySy)

Carcinoma, Non-Small-Cell Lung | Secondary | Advanced Stage IIIB | High Thymidylate Synthase Expression

Italy
Incyte Corporation

Completed

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Metastatic Melanoma | Unresectable Melanoma | Metastatic Urothelial Cancer | Metastatic Non-small Cell Lung Cancer | Locally Advanced Renal Cell Carcinoma | Locally Advanced Urothelial Cancer | Metastatic Clear-Cell Renal Cell Carcinoma

France, Spain, United States, Italy, Austria, Romania, Poland, Hungary
Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Neoplasm Metastasis | Non-Small Cell Lung Cancer

United States, Hong Kong, Spain, Korea, Republic of, China, Israel, Germany, Japan, Singapore, Australia, United Kingdom, Austria, Netherlands, France, Portugal, Sweden, Italy, Belgium
Pfizer

Completed

Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases

Non-Small Cell Lung Cancer

United States, Spain, Italy, France
Amgen

Active, not recruiting

A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC) (DeLLphi-301)

Relapsed/Refractory Small Cell Lung Cancer

United States, Belgium, Italy, Spain, Portugal, Austria, Greece, Korea, Republic of, Denmark, Netherlands, Germany, France, Taiwan, Japan, United Kingdom, Poland, Switzerland, Singapore
Hoffmann-La Roche
Jazz Pharmaceuticals

Active, not recruiting

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer (IMforte)

Small-Cell Lung Cancer

United States, Belgium, Italy, Spain, Turkey, United Kingdom, Korea, Republic of, Germany, Mexico, Hungary, Taiwan, Greece, Poland
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (PALOMA-2)

Carcinoma, Non-small-Cell Lung

United States, Korea, Republic of, Italy, Israel, Malaysia, United Kingdom, China, Brazil, Spain, Germany, Japan, France
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors

United States, Korea, Republic of, Spain, United Kingdom, Brazil, Israel, New Zealand, Netherlands, Canada, Australia, Switzerland, Belgium, Italy, Norway, Poland, Hungary, Kenya, Russian Federation, Germany
Novartis Pharmaceuticals

Completed

Phase I/II Study of PDR001 in Patients With Advanced Malignancies

Melanoma | Triple Negative Breast Cancer | Anaplastic Thyroid Cancer | Other Solid Tumors | Non-small Sell Lung Cancer (NSCLC)

United States, Italy, Spain, Hungary, Taiwan, Germany, Netherlands, France, Norway, Poland, Thailand, Lebanon, Turkey, Canada
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer (JUNIPER)

Non Small Cell Lung Cancer

Italy, United States, Spain, Germany, Korea, Republic of, Poland, Romania, Taiwan, Ukraine, France, Japan, Russian Federation, Austria, Israel, Greece, Brazil, Argentina, Turkey, Canada, Puerto Rico, China
Istituto Clinico Humanitas

Recruiting

Correlation of Metabolic Imaging With Immune Markers in NSCLC Candidate to Immunotherapy.

Carcinoma, Non-Small-Cell Lung | Immunotherapy | Positron-Emission Tomography

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Aflibercept Versus Placebo in Patients With Second-Line Docetaxel for Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (VITAL)

Carcinoma | Non Small Cell Lung

United States, France, Canada, Brazil, Poland, Romania, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Sweden, Bulgaria, Estonia, India, Malaysia, Singapore, Taiwan, Czech Republic, Argentina, Finland, Hungary, Korea... and more
National Cancer Institute, Naples

Completed

G-Step: Gemcitabine Based Small-cell Lung Cancer Treatment in Elderly Patients (G-Step)

Small Cell Lung Cancer

Italy
Celgene

Completed

Study of Amrubicin With or Without Cisplatin Versus Etoposide-cisplatin for Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer

Belgium, United Kingdom, Netherlands, Italy, Poland
CNAO National Center of Oncological Hadrontherapy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy; Fondazione IRCCS... and other collaborators

Recruiting

Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease (ICONIC)

Melanoma | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma

Italy, Germany
PharmaMar

Completed

Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung Cancer (ATLANTIS)

Small-cell Lung Cancer

France, United States, Germany, Spain, Belgium, Lebanon, United Kingdom, Italy, Netherlands, Brazil, Portugal, Greece, Argentina, Austria, Bulgaria, Canada, Czechia, Hungary, Poland, Romania
Alaunos Therapeutics

Unknown

Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer (The MATISSE Study)

Extensive-Stage Small Cell Lung Cancer

United States, Canada, Taiwan, Israel, Italy, Australia, France, Hungary, Poland, Russian Federation, United Kingdom
PharmaMar

Recruiting

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Relapsed Small Cell Lung Cancer

United States, Spain, Japan, Korea, Republic of, United Kingdom, Israel, France, Taiwan, Germany, Australia, Belgium, Georgia, Italy, Switzerland, Denmark, Hungary, Poland, Romania, Canada, Brazil, Bulgaria, Austria, Chile, Turkey
Gruppo Oncologico Italia Meridionale

Unknown

Quality of Life Comparison in Advanced Non-squamous Non Small Cell Lung Cancer (ERACLE)

Non-squamous Nonsmall Cell Neoplasm of Lung

Italy
Nektar Therapeutics
Bristol-Myers Squibb

Completed

A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors (PIVOT-02)

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Urothelial Carcinoma | HR+/HER2- Breast Cancer

United States, Spain, Canada, France, Italy, Belgium, Poland, United Kingdom
AstraZeneca

Completed

Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy. (MERMAID-2)

Carcinoma, Non- Small Cell Lung

United States, Canada, France, Italy, Netherlands, Spain, Belgium, Poland, Taiwan, Vietnam, Korea, Republic of, Brazil, Czechia, Hungary, Japan, Peru, Russian Federation, Hong Kong, Israel, Greece, Australia, Singapore, Turkey, India, A...
Celgene

Active, not recruiting

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Italy, France, Germany, Greece, Spain
Pfizer

Completed

Combination Study Of CP-751,871 With Paclitaxel And Carboplatin In Advanced Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Spain, Canada, Italy
Gruppo Oncologico Italiano di Ricerca Clinica
Istituto Toscano Tumori; Temas srl; Clirest s.r.l.; Mipharm S.p.A.

Unknown

Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLC (Nabster)

Small Cell Lung Cancer

Italy
Celgene

Completed

Safety and Efficacy Study of Nab®-Paclitaxel With CC-486 or Nab®-Paclitaxel With Durvalumab, and Nab®-Paclitaxel Monotherapy as Second/Third-line Treatment for Advanced Non-small Cell Lung Cancer (abound2L+)

Carcinoma, Non-Small-Cell Lung

United States, Canada, France, Germany, Italy, Spain, United Kingdom
Pfizer

Completed

A Study In Patients With Non-Small Cell Lung Cancer Testing If Erlotinib Plus SU011248 (Sunitinib) Is Better Than Erlotinib Alone (SUN1058)

Carcinoma, Non-Small-Cell Lung

United States, Canada, Poland, Romania, Italy, Spain, Netherlands, Hungary
MacroGenics

Active, not recruiting

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors (Tamarack)

Melanoma | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Anal Cancer | Malignant Melanoma | Non-small Cell Carcinoma | Oral Squamous Cell Carcinoma | Small Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Castration-Resistant... and other conditions

Spain, Australia, United States, Korea, Republic of, France, United Kingdom, Italy, Belgium, Poland
Genentech, Inc.
Chugai Pharmaceutical Co.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Gastric Cancer | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma

Korea, Republic of, Spain, Japan, New Zealand, Australia, United States, Italy, Brazil
Boehringer Ingelheim

Completed

A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.

Carcinoma, Non-Small-Cell Lung

Italy, Netherlands, Spain, United Kingdom
Bristol-Myers Squibb

Completed

Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Versus Placebo in Addition to Paclitaxel and Carboplatin

Lung Cancer - Non Small Cell Squamous

Belgium, Brazil, China, Germany, Hong Kong, Japan, Korea, Republic of, Taiwan, Thailand, United States, Spain, Australia, Italy, Netherlands, United Kingdom, Denmark, France, Argentina, Austria, Canada, Chile, Colombia, Czechia, Hungary, Irela... and more
Sanofi

Completed

Evaluation of the Overall Survival of Meclinertant Versus Placebo After a First Line Chemotherapy With Cisplatin + Etoposide (SESAME)

Small Cell Lung Cancer | Lung Cancer | Pulmonary Neoplasms

France, Brazil, Poland, Russian Federation, Australia, Germany, Italy, Spain, Belgium, Mexico, Argentina, Hungary, United Kingdom, Netherlands
Takeda

Completed

A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid Tumors

Carcinoma, Advanced ALK+ or ROS1+Non-Small-Cell Lung, Neoplasm, Advanced ALK+ or ROS1+Solid Tumors

Spain, Italy, Netherlands, France
Eli Lilly and Company

Completed

A Study of LY3023414 in Participants With Advanced Cancer

Non-Hodgkin's Lymphoma | Metastatic Cancer | Malignant Mesothelioma | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Advanced Cancer

United States, Puerto Rico, Italy
AbbVie
Bristol-Myers Squibb

Terminated

A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer

Small Cell Lung Cancer

United States, France, Germany, Italy, Spain
Hoffmann-La Roche

Completed

A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer (MAURIS)

Small Cell Lung Carcinoma

Italy
Mersana Therapeutics
IQVIA Biotech; PSI CRO

Recruiting

First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b

Platinum Resistant Ovarian Cancer | Non Small Cell Lung Cancer Metastatic

United States, Spain, United Kingdom, Australia, France, Austria, Belgium, Bulgaria, Canada, Czechia, Denmark, Finland, Hungary, Italy, Lithuania, New Zealand, Norway, Poland, Sweden
Istituto Clinico Humanitas

Completed

Role of FDG PET, Immune and Hypoxic Marker in NSCLC

Carcinoma, Non-Small-Cell Lung

Italy
Boehringer Ingelheim

Completed

BIBW2992 (Afatinib) in Advanced (EGFR-FISH +) NSCLC (Non Small Cell Lung Cancer) Patients

Carcinoma, Non-Small-Cell Lung

Italy
Seagen Inc.

Recruiting

A Study of SGN-B6A Versus Docetaxel in Previously Treated Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Canada, Japan, Belgium, Spain, France, Poland, Germany, Greece, Italy, Norway, Hungary, Czechia, Netherlands, Romania
Bayer

Completed

A Phase III Randomized, Double-blind, Placebo Controlled Trial Comparing the Efficacy of Gemcitabine, Cisplatin and Sorafenib to Gemcitabine, Cisplatin and Placebo in First-Line Treatment of Patients With Stage IIIb With Effusion and Stage IV Non-Small Cell Lung Cancer (NSCLC) (NEXUS)

Carcinoma, Non-Small-Cell Lung

Belgium, Spain, France, Switzerland, Greece, Italy, Hungary, Canada, Netherlands, United Kingdom, Austria, China, Israel, Mexico, Germany, Brazil, Finland, Cyprus
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Terminated

Phase Ib/II Study of M3814 With Etoposide and Cisplatin in Small Cell Lung Cancer (SCLC) Extensive Disease (ED)

Small Cell Lung Cancer

Belgium, Denmark, Italy, United States, Bulgaria, Canada, Czechia, Germany, Hungary, Poland, Romania, Spain, United Kingdom
Novartis Pharmaceuticals

Terminated

A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Melanoma | Head and Neck Cancer | Pancreatic Cancer | Urothelial Cancer | NSCLC, Non Small Cell Lung Cancer | RCC, Renal Cell Cancer | DLBCL, Diffused Large B Cell Lymphoma | MSS, Microsatellite Stable Colon Cancer | TNBC, Triple Negative Breast Cancer | mCRPC, Metastatic Castration Resistant Prostate...

Belgium, Italy, Taiwan, Germany, Spain, United States, Argentina, Australia, Austria, Czechia, France, Japan, Netherlands, Switzerland, Singapore
Millennium Pharmaceuticals, Inc.

Completed

Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC)

Small Cell Lung Cancer

United States, France, Germany, Spain, Belgium, Poland, Canada, Hungary, Italy, Czechia
European Organisation for Research and Treatment...

Completed

Radiation Therapy to Prevent Brain Metastases in Patients With Previously Treated Extensive-Stage Small Cell Lung Cancer

Lung Cancer

France, United Kingdom, Netherlands, Italy, Israel, Belgium, Egypt, Poland, Turkey, Germany, Cyprus, Hungary

Clinical Trials on Non-small- Cell Lung Cancer (NSCLC) in Italy

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