Clinical Trials on Nonsense Mutations
Total 946 results
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Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
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Massachusetts General HospitalCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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Royal Marsden NHS Foundation TrustCompletedMRI | BRCA1 Mutation | BRCA2 Mutation | MammographyUnited Kingdom
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Università Vita-Salute San RaffaeleIRCCS San Raffaele; Merck Sharp & Dohme LLCUnknownHIV-1 Infected Patients | Fold-change Resistance | Resistance MutationsItaly
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German Breast GroupGlaxoSmithKline; Stemline Therapeutics, Inc.Not yet recruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast CancerGermany
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Intergroupe Francophone de Cancerologie ThoraciqueCompletedCarcinoma, Non-Small-Cell Lung | KRAS Gene Mutation | ALK Gene Mutation | BRAF Gene MutationFrance
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Hellenic Cooperative Oncology GroupActive, not recruitingProstate Cancer Recurrent | Prostate Cancer Metastatic | Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationGreece
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Gynecologic Oncology GroupNational Cancer Institute (NCI)UnknownBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Centre Hospitalier Universitaire de BesanconCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationFrance
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Regeneron PharmaceuticalsRecruitingCongenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF) | Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene | Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) GenesUnited States
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Hunan Province Tumor HospitalRecruitingNon Small Cell Lung Cancer | ALK Gene Mutation | MET Gene Mutation | EGFR Gene Mutation | ROS1 Gene MutationChina
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Istituto Clinico HumanitasCelgeneUnknownAcute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene MutationItaly
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Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States
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Severance HospitalSamsung Medical Center; Asan Medical Center; Kyungpook National University Chilgok...RecruitingBreast Neoplasms | Benign Breast Disease | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene Mutation | Germline Mutation AbnormalityKorea, Republic of
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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Ruijin HospitalRecruitingP53 Mutation | Myeloid Malignancy | MDS | AmlChina
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Blueprint Medicines CorporationCompletedSystemic Mast Cell Activation | KIT D816V MutationUnited States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
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Hubei Biological Medicine Industrial Technology...UnknownAdvanced Solid Tumors | HRD | BRCA MutationChina
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Sohag UniversityRecruiting
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Université de SherbrookeRecruitingTrans-tibial AmputationsCanada
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AstraZenecaCompletedEGFR Mutation Status in aNSCLC PatientsKorea, Republic of, Russian Federation, Malaysia, China, Australia, Taiwan, Thailand, Indonesia, Singapore
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AnHeart Therapeutics Inc.RecruitingIDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid TumorCholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 MutationChina
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Gynecologic Oncology GroupNational Cancer Institute (NCI)WithdrawnBreast Carcinoma | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Hadassah Medical OrganizationUnknownBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
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Pharming Technologies B.V.Laboratory Corporation of America; CMIC Co, Ltd. Japan; Axial Biotech, IncRecruitingAPDS Gene MutationJapan
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The University of Hong KongCompletedAML | FLT3-ITD MutationHong Kong
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Dana-Farber Cancer InstituteJohns Hopkins University; GlaxoSmithKline; Translational Breast Cancer Research...RecruitingBreast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer | Deleterious PALB2 Gene Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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Centre Hospitalier Universitaire de NiceUnknownMitochondrial Diseases | Diagnosis | DNA MutationsFrance
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SUNHO（China）BioPharmaceutical CO., Ltd.Recruiting
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MapKure, LLCRecruitingSolid Tumor | B-Raf Mutation-Related TumorsUnited States, Australia
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PfizerCompletedSolid Tumors Harboring a BRAF V600 MutationUnited States, France, Italy, Singapore, Australia, Spain, Switzerland, Canada, Belgium
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Fujian Cosunter Pharmaceutical Co. LtdUnknownSolid Tumor | C-Met Mutation-Related TumorsChina
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University Health Network, TorontoActive, not recruitingMutation | Hereditary Cancer Syndrome | High-Risk | Germline MutationCanada
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Chang Gung Memorial HospitalIntuitive SurgicalActive, not recruitingBreast Cancer | BRCA1 Mutation | BRCA2 Mutation | Nipple-sparing Mastectomy | Prophylactic MastectomyTaiwan
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Centre Jean PerrinInternational Cancer Research Group; Institut Max Planck d'optique quantiqueRecruitingBRCA1 Mutation | BRCA2 Mutation | Breast Cancer FemaleFrance
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Georgetown UniversityGeorge Washington UniversityEnrolling by invitation
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Oslo Metropolitan UniversitySophies Minde Foundation; UniCare Bakke ASCompleted
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Charite University, Berlin, GermanyUnknownHomozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene MutationGermany
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ArriVent BioPharma, Inc.RecruitingAdvanced Non-Small Cell Lung Cancer | Metastatic Non-Small Cell Lung Cancer | Non-Small Cell Lung Cancer (NSCLC) | HER2 Exon 20 Mutations | EGFR Exon 20 Mutations | EGFR Uncommon Mutations, Including G719X and S768IUnited States, Australia, Spain, United Kingdom, France, Italy, China, Korea, Republic of, Canada, Japan, Netherlands
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Columbia UniversityAmerican Cancer Society, Inc.CompletedBreast Cancer | Ovarian Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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Novartis PharmaceuticalsCompletedNALP3 MutationUnited Kingdom, France, Germany, India, Spain
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BeBetter Med IncXiangya Hospital of Central South UniversityRecruitingAdvanced or Metastatic Solid Tumor | KRAS G12C MutationChina
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HutchmedActive, not recruitingIsocitrate Dehydrogenase Gene MutationUnited States, Spain
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Boehringer IngelheimCompleted