Clinical Trials on Normal Eyes and Ocular Pathology in South Africa

Total 11109 results

Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Tuberculosis | Alcohol Consumption | Treatment Adverse Effect

South Africa
University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; Ospedale... and other collaborators

Not yet recruiting

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis (T3-RCT)

Tuberculosis, Multidrug-Resistant

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); Centers for... and other collaborators

Completed

Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB (Opti-Q)

Tuberculosis, Multidrug-Resistant

South Africa, Peru
National Institute of Allergy and Infectious Diseases...

Completed

Study of Pre-clearance of Latent Tuberculosis Infection And BCG Revaccination

Tuberculosis

South Africa
University of Cape Town

Completed

Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in Children

Kerosene Pneumonitis

South Africa
TASK Applied Science

Completed

Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB (TB_COMBO_01)

Tuberculosis

South Africa
University of Stellenbosch

Completed

Xpert Ultra and Xpert HIV-VL in People Living With HIV

HIV/AIDS | TB - Tuberculosis | Antiretroviral Therapy, Highly Active

South Africa
Case Western Reserve University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Interferon-Gamma Release Assays in Tuberculosis (TB) - HIV Co-infected Children

HIV | Tuberculosis

South Africa
TASK Applied Science
GlaxoSmithKline; European and Developing Countries Clinical Trials Partnership...

Recruiting

EBA, Safety and Tolerability of Sanfetrinem Cilexetil

Tuberculosis, Pulmonary

South Africa
University of Cape Town
Natal Bioproducts Institute

Completed

Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea

Sydenham Chorea | Post Streptococcal Movement Disorder

South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Eclampsia

Eclampsia

South Africa
Swiss Federal Institute of Technology
North-West University, South Africa; Ministry of Health, Tanzania

Completed

Climat Impact on Urinary Iodine Concentration (LION)

Iodine Deficiency

South Africa, Tanzania
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
Jaeb Center for Health Research
National Eye Institute (NEI); Allergan

Completed

Intravitreal Triamcinolone Acetonide Versus Laser for Diabetic Macular Edema (IVT)

Diabetic Macular Edema

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation

Completed

Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 With High Dose - the READ 3 Study (READ 3)

Diabetic Macular Edema

United States
Johns Hopkins University
University of Cape Town Lung Institute; University of Cape Town

Completed

Study of Daily Rifapentine for Pulmonary Tuberculosis

Tuberculosis

South Africa
University of Cape Town
Population Health Research Institute

Completed

A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis (IMPI)

Tuberculous Pericarditis

South Africa
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
University of Stellenbosch
Fundació Institut Germans Trias i Pujol

Recruiting

Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota

Tuberculosis

South Africa
TASK Applied Science
GlaxoSmithKline; Research Center Borstel; Eduardo Mondlane University; Barcelona...

Completed

Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
McGill University Health Centre/Research Institute...
University of Cape Town Lung Institute

Recruiting

A Randomized Controlled Trial of a Digital, Self-testing Strategy for COVID-19 Infection in South Africa.

COVID-19

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of the Performance of Rapid Diagnostics for SARS-CoV-2 Self-testing in the Hands of Untrained (CV009)

COVID-19

South Africa, Uganda
Allergan

Completed

Evaluation of AGN-150998 in Exudative Age-related Macular Degeneration (AMD)

Age-related Macular Degeneration

United States, Italy, Australia, Israel, Germany, Austria, France, Switzerland
Global Alliance for TB Drug Development

Completed

A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)

Pulmonary Tuberculosis

South Africa
Tuberculosis Clinical Diagnostics Research Consortium
University of Cape Town

Unknown

Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Miliary

South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
TASK Applied Science

Completed

BCG Vaccination for Healthcare Workers in COVID-19 Pandemic

COVID-19 | Sars-CoV2

South Africa
University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; University... and other collaborators

Completed

An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis (NEXT)

Tuberculosis | Multidrug Resistant Tuberculosis | Extensively-drug Resistant Tuberculosis

South Africa
TASK Applied Science

Recruiting

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 (BETO)

Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

South Africa
University of Stellenbosch

Recruiting

Host Blood RNA Signatures for Diagnosis of TB (RADIANT)

Tuberculosis | Lower Respiratory Infection

South Africa
Cytheris SA

Terminated

Randomized Study on Multiple Cycles of Interleukin-7 in HIV Patients Immune Non-responders (Inspire 3)

HIV

Switzerland, Italy, South Africa
University of Cape Town

Withdrawn

Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19 (CQOTE)

Covid-19 | HIV

South Africa
Imperial College London
University of Cape Town

Completed

Male Partner Involvement in the Prevention of MTCT of HIV

HIV Infections

South Africa
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy

Geographic Atrophy | Dry Age-related Macular Degeneration

United States
University of Cape Town
University of KwaZulu

Unknown

African Covid-19 Critical Care Outcomes Study

Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
University of Stellenbosch
National Research Foundation of South Africa

Completed

Joint Position Sense in Individuals With Anterior Knee Pain

Proprioceptive Disorders | Anterior Knee Pain Syndrome

South Africa
GlaxoSmithKline

Completed

Study to Asses DTPw-HBV/Hib at 15-18 Months (m) and Mencevax™ ACW at 24 to 30 m in Primed Subjects

Infections, Meningococcal

South Africa
Karolinska Institutet
Philips Healthcare; University of Stellenbosch; ER24

Completed

The Effect of 12 Lead ECG Telemetry on Reperfusion Time in Resource-limited Settings

Myocardial Infarction | STEMI

South Africa
University of Washington
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Not yet recruiting

BIYELA - Bexsero Immunisation in Young Women in Africa

Gonorrhea | Gonorrhea of Pharynx | Gonorrhea of Anus | Gonorrhea of Cervix

South Africa
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment

Drug Resistant Tuberculosis

South Africa
University of Stellenbosch
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Recruiting

Point-of-care Triage Test for Active Tuberculosis (TriageTB)

Tuberculosis | Tuberculosis, Pulmonary

South Africa
University of Washington
National Institute of Mental Health (NIMH)

Completed

Lotto to Link Study: A Prospective, Interventional, Randomized Study of Conditional Incentives

HIV Infections | Incentives | ART

South Africa
Foundation for Professional Development (Pty) Ltd
National Institutes of Health (NIH); University of California, Irvine; National... and other collaborators

Completed

Acceptability and Feasibility of Home-based TB Testing

Tuberculosis, Pulmonary | Households

South Africa
Steba Biotech S.A.

Terminated

Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD

Macular Degeneration | Choroidal Neovascularization

United States, France
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
International Agency for Research on Cancer
World Health Organization; Cheikh Anta Diop University, Senegal; Walter Sisulu... and other collaborators

Active, not recruiting

The Study for the "Cervical Cancer Screening and Treatment Algorithms Study Using HPV Testing in Africa" (CESTA)

HPV Infection

Senegal, South Africa
University of Stellenbosch
New York University

Recruiting

Pre- and Post-treatment Lung Microbiota, Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary Tuberculosis (TB-LUNG)

HIV/AIDS | TB - Tuberculosis

South Africa
Population Council
United States Agency for International Development (USAID); Bill and Melinda...

Completed

Efficacy Study of the Vaginal Gel Carraguard to Prevent HIV Transmission

HIV Infections | Sexually Transmitted Diseases | AIDS | HIV Seroconversion

South Africa
Johns Hopkins University
Aurum Institute; UNITAID; KNCV Tuberculosis Foundation

Completed

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Tuberculosis Infection | Tuberculosis Prevention

Ethiopia, South Africa

Clinical Trials on Normal Eyes and Ocular Pathology in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Rwanda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations