Clinical Trials on Ocular Muscular Dystrophy

Total 53119 results

Mayo Clinic
National Eye Institute (NEI)

Completed

Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.

Retinal Disease | Best Vitelliform Macular Dystrophy | Bestrophinopathy | Adult Onset Vitelliform Macular Dystrophy | Autosomal Dominant Vitreoretinalchoroidopathy

United States
National Eye Institute (NEI)
National Cancer Institute (NCI)

Recruiting

Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

Stargardt-Like Macular Dystrophy

United States
Columbia University
National Eye Institute (NEI); Centre Hospitalier National d'Ophtalmologie des... and other collaborators

Recruiting

Study of BEST1 Vitelliform Macular Dystrophy

Retinitis Pigmentosa | Best Vitelliform Macular Dystrophy

United States, Germany, France
University of Utah

Completed

Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy

Macular Dystrophy, Corneal

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies (MICAI)

Retinal Detachment | Epiretinal Membrane | Macular Holes | Macular Dystrophies

Italy
Astellas Institute for Regenerative Medicine

Completed

Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy

Stargardt's Macular Dystrophy

United States
Astellas Institute for Regenerative Medicine

Completed

Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients

Stargardt's Macular Dystrophy

United States
National Eye Institute (NEI)

Completed

Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy

Macular Degeneration

United States
Astellas Pharma Global Development, Inc.

Active, not recruiting

Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)

Stargardt's Macular Dystrophy

Italy, United States, Israel, United Kingdom, Germany, Spain, Hungary, France
CHABiotech CO., Ltd

Completed

Safety and Tolerability of MA09-hRPE Cells in Patients With Stargardt's Macular Dystrophy(SMD)

Stargardt's Macular Dystrophy

Korea, Republic of
Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Fondazione G.B. Bietti, IRCCS

Recruiting

Micropulsed Laser in Patients With Macular Oedema in Retinal Dystrophies

Macular Edema | Inherited Retinal Dystrophy | Laser Retinopathy

Italy
Istituto Superiore di Sanità
Fondazione G.B. Bietti, IRCCS; Ospedale Pediatrico Bambin Gesù

Recruiting

Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models

Retinitis Pigmentosa | Macular Dystrophy | Inherited Retinal Dystrophy

Italy
University of Oklahoma

Completed

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Age-Related Macular Degeneration | Diabetic Macular Edema | Intravitreal Injection | Ocular Rinse | Cystoid Macular Edema

United States
Wake Forest University Health Sciences

Terminated

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only

Fuchs Dystrophy | Cystoid Macular Edema

United States
Weill Medical College of Cornell University
Riverside Research Institute

Unknown

Ultrasonic Evaluation of Ocular Tissues

Glaucoma | Age-Related Macular Degeneration | Tumors

United States
Escuela Neijing

Completed

Efficacy of Acupuncture in Macular Diseases (AMAD)

Age-related Macular Degeneration | Stargardt Disease | Macular Dystrophy

Colombia
Myotonic Dystrophy Foundation

Recruiting

Myotonic Dystrophy Family Registry (MDFR)

Myotonic Dystrophy | Myotonic Dystrophy 1 | Steinert's Disease | Congenital Myotonic Dystrophy | PROMM (Proximal Myotonic Myopathy) | Steinert Disease | Dystrophia Myotonica 1 | Myotonic Dystrophy 2 | Dystrophia Myotonica | Dystrophia Myotonica 2 | Myotonia Dystrophica | Myotonic Dystrophy, Congenital | Myotonic... and other conditions

United States
Optos, PLC
Johns Hopkins University; University of Southern California

Completed

Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO

Age-Related Macular Degeneration | Diabetic Retinopathy | Macular Edema | Retinal Vein Occlusion | Geographic Atrophy | Epiretinal Membrane | Macular Hole | Pattern Dystrophy of Macula | Central Serous Retinopathy

United States
University Hospital, Montpellier

Unknown

Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy

Duchenne Muscular Distrophy (DMD)

France
Bulent Ecevit University

Completed

Effect of Dexamethasone Implant on Optic Disc

Diabetic Macular Edema | Intravenous Drug Usage | Glaucoma and Ocular Hypertension | Optic Disk Disorders

Turkey
Prim. Prof. Dr. Oliver Findl, MBA

Unknown

Reading Analysis in Ophthalmologic Patients

Glaucoma | Age Related Macular Degeneration | Epiretinal Membrane | Diabetic Maculopathy

Austria
Sensimed AG

Terminated

TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection

Open Angle Glaucoma | Neovascular Age Related Macular Degeneration (AMD)

Spain
Barcelona Macula Foundation

Recruiting

Structural and Functional Characterization of Rare Ocular Diseases (RADIS)

Retinitis Pigmentosa | Choroideremia | Stargardt Disease 1 | Best Disease | Pattern Dystrophy of Macula

Spain
University Hospital, Lille

Recruiting

Study of New Mutations in Cone Disorders (INTROCONE)

Macular Degeneration | Cone Dystrophy | Cone Rod Dystrophy | Retinal Dystrophy, Cone-Rod

France
Evolucare Technologies
Assistance Publique - Hôpitaux de Paris; Slb Pharma; BPIfrance

Recruiting

OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases (OPHTAI-EVAL)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Age-related Maculopathy

France
Eye Hospital Pristina Kosovo

Enrolling by invitation

Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery

Macular Corneal Dystrophy

Kosovo
Southwest Hospital, China

Unknown

Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases

Macular Degeneration | Stargardt's Macular Dystrophy

China
Institute of Molecular and Clinical Ophthalmology...

Recruiting

Function and Imaging Assessments for G1961E-associated Stargardt Disease (FIRSTORBIT)

Stargardt Disease | Stargardt Disease 1 | Fundus Flavimaculatus | Macular Degeneration, Stargardt | Macular Dystrophy With Flecks, Type 1

Switzerland
University of Sao Paulo
Fundação de Apoio ao Ensino Pesquisa e Assitência do HCFMRPUSP

Completed

Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumab

Diabetic Retinopathy | Age Related Macular Degeneration
Nicole Fram M.D.

Recruiting

Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery

Anterior Chamber Inflammation | Ocular Pain | Corneal Edema | Corneal Defect | Corneal Staining | Visual Outcome | CME - Cystoid Macular Edema

United States
Manhattan Eye, Ear & Throat Hospital
Genentech, Inc.

Completed

Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy (FVF4140S)

Polypoidal Choroidal Vasculopathy | Pseudoxanthoma Elasticum | Pathological Myopia | Retinal Angiomatous Proliferation | Coats' Disease | Idiopathic Retinal Telangiectasia | Multi-focal Choroiditis | Rubeosis Iridis | Von Hippel Lindau Disease | BEST VITELLIFORM MACULAR DYSTROPHY, MULTIFOCAL (Disorder)

United States
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Alkeus Pharmaceuticals, Inc.

Recruiting

Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Stargardt Disease | Stargardt Macular Degeneration | Stargardt Macular Dystrophy | Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

United States
Alkeus Pharmaceuticals, Inc.

Enrolling by invitation

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Stargardt Disease | Stargardt Macular Degeneration | Stargardt Macular Dystrophy | Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

United States
Catholic University of the Sacred Heart

Unknown

Saffron Supplementation in Stargardt's Disease (STARSAF02)

Retinal Degeneration | Genetic Disease | Single-Gene Defects | Macular Dystrophy

Italy
Food and Drug Administration (FDA)
National Eye Institute (NEI)

Recruiting

Adaptive Optics Imaging of Outer Retinal Diseases

Age-Related Macular Degeneration | Retinal Degeneration | Retinitis Pigmentosa | Usher Syndromes | Cone Dystrophy | Rod Dystrophy | Cone Rod Dystrophy | Hydroxychloroquine Retinopathy | Late-Onset Retinal Degeneration | Rod Cone Dystrophy

United States
University of Zurich

Unknown

Incidence of Sub-clinical Cystoid Macular Edema After Cataract Surgery (ICCME)

Glaucoma | Cataract

Switzerland
iRenix Medical, Inc.

Terminated

EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN) (CLEAN)

Diabetic Macular Edema | Branch Retinal Vein Occlusion | Glaucoma/Closed Angle Glaucoma

United States
University of Toronto
Ontario Research Fund

Unknown

Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye

Glaucoma | Age Related Macular Degeneration | Diabetic Retinopathy.

Canada
University Hospital, Grenoble
Laboratoire de Psychologie et NeuroCognition

Terminated

Deficits, Adaptation and Cerebral Functional Reorganization of Visual Retinotopic Treatments During Normal and Pathological Aging (Age-related Macular Degeneration and Glaucoma) (VISIOPERICENT)

Glaucoma | Macular Degeneration

France
Medical University of Vienna

Completed

Does Complement Factor H Gene Polymorphism Play a Role in the Regulation of Vascular Tone in the Choroid?

Macular Degeneration | Ocular Physiology | Regional Blood Flow | Genetic Polymorphism

Austria
National Eye Institute (NEI)

Terminated

Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)

Inherited Retinal Degeneration | Inherited Ophthalmic Diseases

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Recruiting

Macular Pigment Optical Density in Primary Angle-closure Disease

Glaucoma | Glaucoma, Angle-Closure | Macular Pigment Optical Density

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating MYO-029 in Adult Muscular Dystrophy

Becker Muscular Dystrophy | Facioscapulohumeral Muscular Dystrophy | Limb-Girdle Muscular Dystrophy

United States
Oregon Health and Science University
National Eye Institute (NEI)

Completed

CEI Van Outreach Screening Study

Glaucoma | Keratoconus | Macular Disease

United States
Massachusetts General Hospital
University of Pittsburgh; Boston Children's Hospital; Brigham and Women's Hospital and other collaborators

Recruiting

Biomarker Development for Muscular Dystrophies

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Myotonic Dystrophy | Facioscapulohumeral Muscular Dystrophy

United States
Alkeus Pharmaceuticals, Inc.

Completed

Phase 1 Safety Study of ALK-001 in Healthy Volunteers

Age-related Macular Degeneration | Stargardt Disease | Other Retinal Dystrophies
Centre Hospitalier National d'Ophtalmologie des...

Recruiting

Multimodal Ophthalmic Imaging (IMA-MODE)

Stroke | Glaucoma | Hypertension | Diabetes | Retinal Degeneration | Macular Edema | Retinitis Pigmentosa | Trauma | Dry Eye | Keratoconus | Retinal Detachment | Corneal Dystrophy | Vascular Inflammation | Macular Dystrophy | Maculopathy, Age Related

France

Clinical Trials on Ocular Muscular Dystrophy

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