Clinical Trials on Open Angle or Ocular Hypertension

Total 2621 results

AbbVie

Completed

A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Allergan

Completed

Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

China
Bausch & Lomb Incorporated

Completed

Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension (LUNAR)

Ocular Hypertension | Open-Angle Glaucoma

United States
Bausch & Lomb Incorporated

Completed

Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension (APOLLO)

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research
Novartis Institute for BioMedical Research

Completed

A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma

Ocular Hypertension | Open-Angle Glaucoma
Aerie Pharmaceuticals

Completed

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Glaukos Corporation

Completed

Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost

Open-angle Glaucoma

Armenia
Merck Sharp & Dohme LLC

Completed

Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Allergan

Completed

A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
FinnMedi Oy
Tampere University; The Laboratory and Pharmacy Public Utility of the Pirkanmaa...

Completed

The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

Finland
Alcon Research

Completed

A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety and Efficacy of Travoprost/Timolol BAC-free

Ocular Hypertension | Open-Angle Glaucoma

Japan
Alcon Research

Completed

Travoprost New Formulations in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Efficacy of Changing to TRAVATAN® From Prior Therapy

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Patient Preference Comparison of AZARGA Versus COSOPT

Ocular Hypertension | Open-Angle Glaucoma
Mati Therapeutics Inc.
QLT Inc.

Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

Travoprost 3-Month Safety and Efficacy Study

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
Santen Oy

Completed

Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety and Intraocular Pressure (IOP) Lowering Efficacy of Low Dose Travoprost

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients

Ocular Hypertension | Open-angle Glaucoma
Santen Oy

Completed

Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations

Ocular Hypertension | Open-angle Glaucoma

Hungary
Santen Pharmaceutical Co., Ltd.

Completed

To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Japan
Alcon Research

Completed

Phase 3 Study Comparing IOP Lowering in OAG or OH in Japanese Subjects C-01-98

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70

Ocular Hypertension | Open-Angle Glaucoma

United States
Julie Dawson

Completed

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. (CMO)

Open Angle Glaucoma and Cataract

United Kingdom
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Columbia University

Recruiting

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

Primary Open Angle Glaucoma

United States
Hospital Clinic of Barcelona

Completed

Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery Outcomes (IIT_XEN)

Glaucoma | Glaucoma Open-Angle Primary

Spain
Transcend Medical, Inc.

Completed

Safety and Performance Study of the CyPass System Applier Model 241 (RePASS)

Open Angle Glaucoma (OAG)

Germany
Federico II University

Completed

OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients

Glaucoma Open-Angle Primary

Italy
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma

Open-Angle Glaucoma

United States, Australia
Ivantis, Inc.

Completed

Hydrus Microstent for Refractory Open-Angle Glaucoma (SUMMIT)

Open-angle Glaucoma

Spain, United States, United Kingdom, Philippines, Colombia
Glaukos Corporation

Completed

Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty

Open-angle Glaucoma

Armenia
Annexon, Inc.

Completed

Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma

Open-angle Glaucoma

United States
Alcon Research

Terminated

Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Ocular Hypertension | Open-Angle Glaucoma

United States
Lv Yingjuan

Completed

The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork

Open-angle Glaucoma

China
Wills Eye

Completed

Dose, Effects and Characteristics of Pilocarpine

Open-angle Glaucoma

United States
Vistakon Pharmaceuticals

Completed

Safety and Efficacy of a Drug Delivery System in Glaucoma

Ocular Hypertension | Open-angle Glaucoma

United States
Alcon Research

Completed

Efficacy of Changing to TRAVATAN® From Prior Therapy

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma

Open-angle Glaucoma

United States
Alcon Research

Completed

DuoTrav® Eye Drops As Replacement Therapy Program

Ocular Hypertension | Open-angle Glaucoma

China
Aeon Astron Europe B.V.

Unknown

Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in Germany

Open-angle Glaucoma

Germany
Santen Oy

Completed

Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops

Ocular Hypertension | Open-Angle Glaucoma

Finland

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