Clinical Trials on Open-angle Glaucoma (OAG)

Total 939 results

Glaukos Corporation

Completed

A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma (SY)

Glaucoma | Glaucoma, Open-Angle | Eye Diseases

Spain, France, Armenia, Germany, Austria, Italy
Sooft Italia

Withdrawn

Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Maximum Tolerated Medical Therapy

Primary Open Angle Glaucoma | Intraocular Pressure

Italy
University Hospital of Patras

Completed

Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma

Primary Open-angle Glaucoma | Pseudoexfoliation Glaucoma
Lv Yingjuan

Completed

Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle Glaucoma

Vitamin D Deficiency | Primary Open- Angle Glaucoma

China
Julie Dawson

Completed

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. (CMO)

Open Angle Glaucoma and Cataract

United Kingdom
Ivantis, Inc.

Completed

Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery

Primary Open Angle Glaucoma | Pseudoexfoliative Glaucoma | Pigmentary Dispersion Glaucoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Efficacy Mydrane ® for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma. (MIGA)

Cataract Surgery

Italy
Whitecap Biosciences, LLC

Completed

Safety and IOP-Lowering Effects of WB007

Ocular Hypertension | Glaucoma, Primary Open Angle

United States
Qlaris Bio, Inc.

Completed

Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing Xalacom And Xalatan In Patients With Primary Open Angle Glaucoma (POAG) Or Ocular Hypertension (OH).

Ocular Hypertension | Glaucoma

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United Kingdom, France, Australia, Thailand, Portugal, Pakistan, Czechia, Greece
Laboratoires Thea

Completed

Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose

Primary Open Angle Glaucoma | Ocular Hypertension

France
Laboratorios Sophia S.A de C.V.

Terminated

Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension (COMPLIANCE)

Primary Open Angle Glaucoma | Ocular Hypertension

Mexico
Nephron Pharmaceuticals Corporation

Completed

Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Glaucoma

United States, Singapore
Santen Pharmaceutical Co., Ltd.

Completed

A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-

Primary Open Angle Glaucoma | Ocular Hypertension

Japan
Chong Kun Dang Pharmaceutical

Unknown

Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily

Ocular Hypertension | Glaucoma, Primary Open Angle

Korea, Republic of
Germans Trias i Pujol Hospital
Pau Romera Romero; Jorge Loscos Arenas; Nevena Romanic Bubalo; Jordi Castellví...

Unknown

Changes in Choroidal Thickness After Non Penetrating Deep Sclerectomy

Open Angle Glaucoma | Choroidal Thickness | Non Penetrating Deep Sclerectomy

Spain
Alcon Research
University of California, San Diego

Completed

Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
ForSight Vision5, Inc.

Completed

A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

Latvia
Azienda Socio Sanitaria Territoriale degli Spedali...
Aristotle University Of Thessaloniki

Completed

Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) (SAF-24H-IOP)

Primary Open Angle Glaucoma | Ocular Hypertension

Greece, Italy
Northwestern Ophthalmic Institute S.C.
Research to Prevent Blindness

Completed

Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Medical University of Vienna

Recruiting

Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma

Glaucoma

Austria
University of California, Los Angeles
National Eye Institute (NEI)

Active, not recruiting

Advanced Glaucoma Progression Study (AGPS)

Primary Open Angle Glaucoma | Chronic Angle Closure Glaucoma | Pseudoexfoliative Glaucoma

United States
Laboratoires Thea

Not yet recruiting

Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
Glaukos Corporation

Recruiting

Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
JeniVision, Inc.

Suspended

Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Nicox Ophthalmics, Inc.

Completed

Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Mont Blanc)

Ocular Hypertension | Open Angle Glaucoma

United States
Sun Pharma Advanced Research Company Limited

Completed

Evaluation of Safety and Efficacy of PDP-716

Ocular Hypertension | Open Angle Glaucoma

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Non Interventional Study in Patients With Open Angle Glaucoma and/or Ocular Hypertension Treated With XALATAN®

Ocular Hypertension | Glaucoma,Open-Angle
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma

Ocular Hypertension | Open Angle Glaucoma

United States
Centre of Postgraduate Medical Education

Unknown

OMNI in Open-angle Glaucoma Treatment

Glaucoma | Eye Diseases | Cataract | Open Angle Glaucoma

Poland
ViSci Ltd.

Completed

A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

United States
Merck Sharp & Dohme LLC

Completed

Dry Eye Study With Cosopt® Over 8 Weeks in Patients With Open-Angle Glaucoma or Ocular Hypertension (0507A-152)(COMPLETED) (DISCOVER)

Ocular Hypertension | Open Angle Glaucoma
Alcon Research

Completed

6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma
Aerie Pharmaceuticals

Completed

24-hour Efficacy of AR-12286

Ocular Hypertension | Open Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open Angle Glaucoma

Canada
Mati Therapeutics Inc.

Completed

A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Sylentis, S.A.

Completed

Dose Finding Clinical Trial With SYL040012 to Evaluate the Tolerability and Effect on Intraocular Pressure in Subjects With Ocular Hypertension or Open Angle Glaucoma

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, Estonia
DBYAN Medicine Professional Corporation
Allergan

Completed

A Investigator Masked Parallel Comparison of Tolerability of Combigan and Cosopt (CICOM1010)

Ocular Hypertension | Open Angle Glaucoma

Canada
Alcon Research

Withdrawn

Three Month Safety and Efficacy Study of TRAVATAN® Versus Travoprost Ophthalmic Solution, 0.004%

Ocular Hypertension | Open Angle Glaucoma
Pfizer

Completed

A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma | Open Angle Glaucoma

United States
Alfred E. Tiefenbacher (GmbH & Co. KG)

Completed

Equivalence Study of Dorzolamide 2% Eye Drops Solution

Ocular Hypertension | Open Angle Glaucoma

Germany
Ciliatech

Not yet recruiting

Clinical Study Evaluating the Efficacy and Safety of CID v2.2 in Glaucoma Surgery (SAFARI4)

Glaucoma, Open-Angle | Glaucoma, Narrow Angle
Universitaire Ziekenhuizen KU Leuven

Completed

Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation

Open Angle Glaucoma | Low Tension Glaucoma

Belgium
Nova Eye, Inc.
Nova Eye Medical GmbH

Recruiting

Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma (CATALYST)

Primary Open Angle Glaucoma

Germany
Alcon Research

Completed

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent (COMPASS XXT)

Primary Open Angle Glaucoma | Cataract

United States
Sensimed AG

Withdrawn

TF for the Prediction of Visual Field Progression

Open Angle Glaucoma
Medical University of Vienna

Recruiting

Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study

Primary Open-angle Glaucoma | Macular Degeneration, Dry

Austria
The University of Hong Kong
Icare Finland Oy

Not yet recruiting

Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression

Primary Open Angle Glaucoma | Glaucoma | Intraocular Pressure

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