Clinical Trials on Open-Angle Glaucoma in United States

Total 1015 results

Glaukos Corporation

Completed

Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Cohort

Primary Open Angle Glaucoma

United States
Altheos, Inc.

Completed

ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular Hypertension (OHT) Subjects

Primary Open Angle Glaucoma | Ocular Hypertension

United States
[Redacted]

Withheld

[Trial of device that is not approved or cleared by the U.S. FDA] (FRONTIER)

Primary Open Angle Glaucoma | Open Angle Glaucoma | Pseudoexfoliation Glaucoma | Pigmentary Glaucoma

United States, Germany, Italy, Philippines, Spain, United Kingdom
Wills Eye
IOP Ophthalmics

Terminated

Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube

Primary Open Angle Glaucoma | Neovascular Glaucoma | Uveitic Glaucoma | Pseudoexfoliation Glaucoma | Primary Angle Closure Glaucoma | Pigmentary Glaucoma | Traumatic Glaucoma

United States
MediPrint Ophthalmics, Inc.

Completed

Study of LL-BMT1 in Patients With Elevated Intraocular Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Aerie Pharmaceuticals

Completed

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

Primary Open Angle Glaucoma or Ocular Hypertension

United States
InnFocus Inc.

Completed

InnFocus MicroShunt Versus Trabeculectomy Study (IMS)

Primary Open Angle Glaucoma

Spain, United States, United Kingdom, France, Netherlands, Italy
Nova Eye, Inc.
Nova Eye Medical GmbH

Recruiting

Multicenter Glaucoma Study Investigating Standalone Canaloplasty (MAGIC)

Primary Open Angle Glaucoma

United Kingdom, Germany, Spain
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma

Ocular Hypertension | Open Angle Glaucoma

United States
Inotek Pharmaceuticals Corporation

Completed

A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
AqueSys, Inc.

Completed

Evaluation of the XEN Implant in Moderate Primary Open Angle Glaucoma (POAG) Participants

Primary Open Angle Glaucoma

Spain, Austria, Belgium, Italy, Germany, Poland, Switzerland, United Kingdom, Venezuela
InSight Vision Center Medical Group, Inc

Recruiting

Hydrus Microstent as a Quality of Life Consideration

Open Angle Glaucoma

United States
University of Colorado, Denver

Completed

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Hypertension, Ocular | Glaucoma, Open-angle

United States
Alcon Research

Recruiting

Hydrus® Microstent New Enrollment Post-Approval Study (CONFIRM)

Primary Open Angle Glaucoma

United States
Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
59th Medical Wing
Nanodropper, Inc.

Recruiting

Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Mati Therapeutics Inc.

Completed

Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Glaucoma

United States
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-angle

United States
Eye Therapies, LLC

Completed

Study Evaluating the Safety and Intraocular Pressure (IOP) Lowering Response of Brimonidine Tartrate Ophthalmic Solution in Subjects With Open Angle Glaucoma or Ocular Hypertension

Glaucoma and Ocular Hypertension

United States
Uzoma Chinyei Joan

Recruiting

Comparison of Preserved and Preservative-free Latanoprost 0.005% in Primary Open Angle Glaucoma and Ocular Hypertensive Patients, at Guinness Eye Centre, Lagos.

Effect of Drug

Nigeria
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

Glaucoma

United States, Singapore
Ocular Therapeutix, Inc.

Completed

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Ocular Hypertension | Open Angle Glaucoma

United States
Altheos, Inc.

Unknown

Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertension

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Chicago Center for Vision Research

Completed

Study of Medical Treatment of Low-Pressure (Normal Tension) Glaucoma

Glaucoma, Open Angle

United States
Novartis

Completed

Tolerability, Safety and Efficacy of RKI983 Eye Drops in Subjects With Primary Open Angle Glaucoma and Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
University of California, San Francisco
University of Colorado, Denver; University of Maryland; Zhongshan Ophthalmic... and other collaborators

Completed

Ahmed Glaucoma Valve Surgery With Mitomycin-C (AMCT)

Primary Open Angle Glaucoma | Glaucoma | Neovascular Glaucoma | Secondary Glaucoma

United States, China, India, Mexico
Mati Therapeutics Inc.

Completed

Safety and Efficacy of Punctum Plug Delivery System in Subjects With Open-Angle Glaucoma or Ocular Hypertension (CORE)

Ocular Hypertension | Glaucoma

United States
Alcon Research

Completed

Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent (COMPASS XXT)

Primary Open Angle Glaucoma | Cataract

United States
Glaukos Corporation

Active, not recruiting

Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery

Primary Open Angle Glaucoma

United States
Alleanza Pharmaceuticals, Inc.

Completed

Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost

Primary Open Angle Glaucoma | Ocular Hypertension | Elevated Intraocular Pressure

United States
Sylentis, S.A.

Completed

SYL040012, Treatment for Open Angle Glaucoma (SYLTAG)

Ocular Hypertension | Open Angle Glaucoma

Spain, Germany, United States, Estonia
Julie Dawson

Completed

RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery. (CMO)

Open Angle Glaucoma and Cataract

United Kingdom
Aerie Pharmaceuticals

Completed

Study of AR-13324 in Patients With Elevated Intraocular Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
University of California, San Diego
Genentech, Inc.

Completed

STudy to Assess Rapid Disease Progression by Clinical and Genetic Factors In Glaucoma patientS That Are High Risk (STARFISH)

Primary Open Angle Glaucoma

United States
Glaukos Corporation

Completed

Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG) (SL)

Glaucoma | Glaucoma, Open-Angle | Eye Diseases

Spain, France, Austria, Italy, Armenia, Germany, Greece, Poland, United Kingdom
Mati Therapeutics Inc.

Completed

A Dose Evaluation Study for the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

Glaucoma | Ocular Hypertension (OH)

United States
Ivantis, Inc.

Completed

Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)

Primary Open Angle Glaucoma

United States, Poland, United Kingdom, Spain, Canada, Germany, Italy, Mexico, Philippines
University of North Carolina, Chapel Hill
National Eye Institute (NEI); American Glaucoma Society

Terminated

Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma

Primary Open Angle Glaucoma | Ocular Hypertension | Cataract | Low Tension Glaucoma

United States
Pfizer

Completed

A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma | Open Angle Glaucoma

United States
Hoffmann-La Roche

Completed

A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma

Hypertension, Glaucoma, Open-Angle

United States, Bulgaria, Czech Republic, Hungary
Aerie Pharmaceuticals

Completed

A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days

Ocular Hypertension | Open Angle Glaucoma

United States
Amakem, NV

Completed

Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma

Ocular Hypertension | Glaucoma | Eye Disease

United States
Aerie Pharmaceuticals

Completed

Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure

Ocular Hypertension | Open Angle Glaucoma

United States
Actavis Inc.

Completed

Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Glaucoma

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom

Ocular Hypertension | Open Angle Glaucoma

United Kingdom
Amakem, NV

Completed

Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma | Eye Disease

United States
Nicox Ophthalmics, Inc.

Recruiting

MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

Ocular Hypertension | Open Angle Glaucoma

United States, China
Alcon Research

Completed

Glaucoma Adherence Study (GAS)

Primary Open Angle Glaucoma | Ocular Hypertension

France, Italy, Netherlands, United Kingdom
University of Plymouth

Completed

Advanced Glycation End Products as a Biomarker for Accelerated Ageing

Primary Open Angle Glaucoma | Ocular Hypertension | Normal Tension Glaucoma

United Kingdom

Clinical Trials on Open-Angle Glaucoma in United States

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