Clinical Trials on Opiate Dependence

Total 2284 results

NYU Langone Health
Forest Laboratories

Completed

A Clinical Trial of Acamprosate for Treatment of Methamphetamine Addiction (AcampMet)

Methamphetamine Dependence, Treatment Seeking

United States
Juul Labs, Inc.

Completed

Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

New Zealand
Yale University
National Cancer Institute (NCI)

Completed

Alcohol Counseling for Telephone Quitline Callers

Smoking | Alcohol Dependence | Nicotine Dependence

United States
Mayo Clinic

Completed

Varenicline Treatment for Active Alcoholic Smokers

Smoking | Alcohol Dependence | Tobacco Dependence

United States
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment)

Alcohol Dependence | Drug Dependence

United States
University of Washington
U.S. Army Medical Research and Development Command

Completed

Efficacy Trial of Warrior Check-Up

Alcohol Dependence | Substance Abuse | Alcohol Abuse | Substance Dependence

United States
National Institute on Alcohol Abuse and Alcoholism...

Completed

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

Alcohol Abuse | Alcohol Dependence (Primary Condition)

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Direct Transcranial Electrical Stimulation in Tobacco Addiction (tDCS) (tDCS)

Adults (Male and Female Subjects) With Tobacco Dependence

France
Orexo AB
Worldwide Clinical Trials

Completed

Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence

Opioid Dependence, on Agonist Therapy

United States
Universiti Sains Malaysia
Yale University

Unknown

An Open-label Study of Oral Paliparidone for the Treatment of Patients With Co-occurring Opioid and ATS Dependence

Heroin Dependence | Amphetamine Dependence

Malaysia
Universiti Sains Malaysia
Yale University

Unknown

An Open Label Study of Oral Minocycline for the Treatment of Patients With Co-occurring Opioid and ATS Dependence

Heroin Dependence | Amphetamine Dependence

Malaysia
Steve N. Caritis, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

Pregnancy | Opiate Addiction

United States
University of Pittsburgh

Completed

Impact of Pregnancy on Buprenorphine Pharmacokinetics and Pharmacodynamics

Pregnancy | Opiate Addiction

United States
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Completed

Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia (Harapan)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence
Butler Hospital
National Institute on Drug Abuse (NIDA)

Completed

Insomnia and Drug Relapse Risk

Opiate Addiction | Poor Quality Sleep

United States
International Center for Ethnobotanical Education...
University of Sao Paulo; Universidad Autonoma de Madrid; University Rovira i... and other collaborators

Recruiting

Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification

Opioid Dependence | Drug Dependence | Drug Use Disorders

Spain
Pop Test Oncology LLC
Baylor College of Medicine; Michael E. DeBakey VA Medical Center; Congressionally... and other collaborators

Completed

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Potential Treatment for Alcohol Dependence-Alcohol Interaction

United States
Ryan M. Carnahan
University of Utah; University of New Mexico

Completed

Pilot TMS for Methamphetamine Use Disorder

Methamphetamine-dependence | Stimulant Dependence | Addiction, Drug

United States
Mclean Hospital
Brain & Behavior Research Foundation

Terminated

Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With Schizophrenia (DCCS)

Cannabis Dependence | Marijuana Dependence

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA); Omeros Corporation

Terminated

Pioglitazone for Heroin and for Nicotine Dependence

Heroin Dependence | Nicotine Dependence

United States
Universiti Sains Malaysia
Yale University

Unknown

Mirtazapine as a Treatment for Co-Occurring Opioid and ATS Dependence in Malaysia

Heroin Dependence | Amphetamine Dependence

Malaysia
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); Harvard University; Mind and Life Institute...

Unknown

Effects of Intensive Behavioral Training Program on Impulsivity and Inhibitory Control in Smokers (IBTP)

Tobacco Smoking | Addiction | Nicotine Dependence | Substance Dependence | Impulsivity

United States
University of Texas Southwestern Medical Center
Stanley Medical Research Institute; University of North Texas Health Science...

Completed

A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence

Bipolar Disorder | Cocaine Dependence | Methamphetamine Dependence

United States
Prof. Dominique de Quervain, MD
Psychiatric Hospital of the University of Basel

Terminated

Effects of Glucocorticoids on Craving During Detoxification Treatment of Heroin and/or Stimulants (Goliath)

Opioid Dependence | Cocaine Dependence

Switzerland
Orexo AB
Worldwide Clinical Trials

Completed

Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults (ISTART)

Opioid Dependence, on Agonist Therapy

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA); Yale University

Completed

Pharmacogenetics of Disulfiram for Cocaine (Disulfiram)

Opioid Dependence | Cocaine Dependence

United States
Yale University

Completed

Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients. (Keppra)

Opioid Dependence | Cocaine Dependence

United States
Juul Labs, Inc.
Celerion

Completed

Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers (Diamond)

Tobacco Use | Smoking, Tobacco | Nicotine Dependence, Other Tobacco Product

United States
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Addiction Health Evaluation And Disease Management (AHEAD) Study

Alcohol Dependence | Alcoholism | Drug Dependence

United States
Hurd,Yasmin, Ph.D.
Jazz Pharmaceuticals

Completed

Acute and Short-term Effects of CBD on Cue-induced Craving in Drug-abstinent Heroin-dependent Humans

Opiate Addiction

United States
University of Malaga

Not yet recruiting

Innovative Physical Therapy Modalities in People With a Neurological Disease: Oculomotor Therapy and Adapted Yoga (NeuPhysioLRG)

Nervous System Diseases | Treatment Adherence | Physical Inactivity | Oculomotor; Disorder | Physical Dependence

Spain
Oregon Health and Science University

Recruiting

rTMS for Craving in Methamphetamine Use Disorder

Transcranial Magnetic Stimulation | Methamphetamine-dependence | Substance Use Disorders | Stimulant Dependence | Methamphetamine Abuse | Stimulant Use

United States
Juul Labs, Inc.

Completed

United States Pre-Market Tobacco Application Pharmacokinetics (US-PMTA-PK)

Tobacco Use | Tobacco Smoking | Nicotine Dependence | Nicotine Dependence, Cigarettes

United States
Inventage Lab., Inc.

Not yet recruiting

A Clinical Trial to Assess Pharmacokinetic Profiles and Safety of IVL3004

Alcohol Dependence | Opioid Dependence
Rowan University
University of Kentucky

Recruiting

Re-Connect Application for Smoking Cessation

Smoking Cessation | Nicotine Dependence, Cigarettes | Acceptability of Health Care

United States
Juul Labs, Inc.
Rose Research Center, LLC

Completed

A Study to Characterize Puff Topography With Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adult Smokers

Tobacco Use | Tobacco Smoking | Nicotine Dependence, Other Tobacco Product

United States
Macmillan Research Group UK
NMP Medical Research Institute; Warwick Research Services

Completed

Impact of Prevention Awareness Group (PAG) on Treatment Attendance and Drug Abstinence Among Substance User

Alcohol Dependence | Substance Use Disorder | Drug Dependence,

India
New York State Psychiatric Institute

Suspended

Vaped Marijuana to Attenuate Naloxone-Precipitated Withdrawal

Opioid Overdose

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens

Opioid Overdose

United States
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Real Prevention, LLC
Indiana University

Completed

Developing and Testing the Opioid Rapid Response System

Opioid Overdose

United States
Medical College of Wisconsin

Withdrawn

Neurostimulation for Opiate Withdrawal in the PICU (NOW)

Opiate Withdrawal Syndrome

United States
Member Companies of the Opioid PMR Consortium
Kaiser Permanente; World Health Information Science Consultants, LLC

Completed

Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse
Kevin Watt
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetics of Multiple Dose Methadone in Children Treated for Opiate Withdrawal (MTH01)

Opiate Withdrawal Syndrome

United States
University of Pennsylvania
Medical University of South Carolina; United States Department of Defense; VA... and other collaborators

Completed

Preventing Risky Drinking in Veterans Treated With Prescription Opioids

Alcohol Drinking | Pain | Opiates

United States
Indiana University
National Institute on Drug Abuse (NIDA)

Enrolling by invitation

Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder

Substance-Related Disorders | Pregnancy Related | Narcotic-Related Disorders | Opioid Use Disorder | Buprenorphine Dependence | Methadone Dependence

United States
Shanghai Zhongshan Hospital

Recruiting

The Ability of Peripheral Perfusion Index To Detect Changes of Hemodynamics in Patients With Pacemaker

Pacemaker Dependence

China
REGINA ALLANDE CUSSO

Completed

Implementing the Transcultural Social-Ethical-Care Model -TEC-MED for Older People in the Mediterranean Basin (TEC-MED)

Older People | Social Exclusion | Care Dependency

Spain
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Withdrawn

Cigarette Harm Reduction With Electronic Cigarette Use (NIDA-SREC)

Cardiovascular Risk Factor | Nicotine Dependence | Nicotine Dependence, Cigarettes | Nicotine Withdrawal | Tobacco Toxicity

United States
Indiana University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Reactions to E-cigs and Alcohol

Alcohol Abuse | Nicotine Dependence Tobacco Product

United States

Clinical Trials on Opiate Dependence

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CROs in United States

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