Clinical Trials on Optic Nerve Glioma

Total 10335 results

Retina Institute of Hawaii
Eyetech Pharmaceuticals

Available

A Single-Center Trial of High Frequency Pegaptanib for Rapid Restoration of VEGF Levels in Diabetic Retinal Edema (GUARDIAN)

Diabetic Macular Edema

United States
Henry Friedman

Completed

Pilot Study of Bone Marrow/Stem Cells in Grade IV Malignant Glioma

Grade IV Malignant Glioma

United States
Annick Desjardins
Amgen

Terminated

Panitumumab and Irinotecan for Malignant Gliomas

Malignant Glioma of Brain

United States
Illinois Institute of Technology
Johns Hopkins University; University of Chicago; National Institute of Neurological... and other collaborators

Recruiting

A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness (ICVP)

Optic Nerve Diseases | Ocular Injury | Photoreceptor Degeneration | Blindness,Acquired

United States
Medical University of Lublin

Completed

Comparison of Efficacy and Safety of Mitomycin and Aflibercept Used to Support Primary Trabeculectomy.

Eye Diseases | Glaucoma Surgery | Optic Nerve Damage

Poland
Centre Hospitalier National d'Ophtalmologie des...
Roche Chugai

Recruiting

Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA (TOCIAION)

Giant Cell Arteritis | Optic Ischaemic Neuropathy

France
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Cellular Immunotherapy Study for Brain Cancer (alloCTL)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Gliomas | Anaplastic Mixed Glioma | Malignant Meningioma

United States
Dartmouth-Hitchcock Medical Center

Completed

Protocol to Distinguish Tumor Recurrence From Treatment-Related Necrosis in Patients With High Grade Gliomas

Recurrent High Grade Gliomas

United States
Memorial Sloan Kettering Cancer Center
Columbia University; University of Wisconsin, Madison; Keryx Biopharmaceuticals; Keryx / AOI Pharmaceuticals, Inc... and other collaborators

Completed

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

Cancer | Brain Cancer | Malignant Gliomas | CNS

United States
Duzce University

Completed

Cerebral Oxymeter and End Tidal Carbondioxide Values Under Surgical Drapes With and Without Past COVID-19 Infection

Anesthesia, Local | Cataract Extraction | Optic Nerve Sheath

Turkey
National Cancer Institute (NCI)

Recruiting

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype

Glioma | Glioblastoma | Malignant Glioma | Low Grade Glioma | High Grage Glioma

United States
Kentuckiana Cancer Institute
Eisai Inc.

Unknown

Radiation With Concomitant and Then Sequential Temozolomide in Malignant Glioma

Newly Diagnosed Supratentorial Malignant Glioma

United States
Medical College of Wisconsin

Not yet recruiting

A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas

Glioma | Brain Cancer | Brain Tumor | Glioma Intracranial | Gliomas Benign | Motor Cortex; Lesion
Martin-Luther-Universität Halle-Wittenberg
Merck KGaA, Darmstadt, Germany

Terminated

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents (HGG-CilMetro)

Gliomas

Germany
Eli Lilly and Company
National Cancer Institute (NCI)

Completed

A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas

Recurrent Gliomas

United States
Hospital Hietzing

Completed

Treatment of Diabetic Macular Edema (DME) With Anti-VEGF and Focal Laser

Diabetic Retinal Edema

Austria
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Glioblastoma | Malignant Glioma | WHO Grade III Glioma | Recurrent Glioma | Refractory Glioma

United States
Amgen

Completed

A Phase II Study to Treat Advanced Malignant Glioma

Advanced Malignant Glioma
Mayo Clinic
National Cancer Institute (NCI)

Completed

Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers

Glioblastoma | Malignant Glioma | WHO Grade III Glioma

United States
Amgen

Completed

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Glioblastoma or Malignant Glioma

United States, Australia, Netherlands, Germany, Spain, France
Duke University
Monteris Medical

Withdrawn

LITT Palliative Treatment for Patients With Malignant Gliomas

Glioblastoma | Malignant Glioma of Brain

United States
Institut de Recherches Internationales Servier

Active, not recruiting

Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)

Recurrent Glioma | Grade 2 Glioma | Residual Glioma

United States, Canada, Spain, Italy, United Kingdom, Switzerland, Israel, Japan, Netherlands, Germany, France
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Pregnancy | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Atypical Hemolytic Uremic Syndrome (aHUS) | Ultomiris-exposed Pregnant/ Postpartum | Generalized Myasthenia Gravis (gMG) | Neuromyelitis Optica Spectrum Disorder (NMOSD)
Retina Specialists, PC
Allergan

Completed

Ozurdex for Macular Edema Post Membrane Peeling

Macular Edema | Epiretinal Membrane | Retinal Edema | Cellophane Maculopathy

United States
Augenabteilung Allgemeines Krankenhaus Linz

Completed

Isometric Exercise in NTG

Mean Blur Ratio

Austria
Beijing Tiantan Hospital

Recruiting

China National Registry of Neuro-Inflammatory Diseases (CNRID)

Multiple Sclerosis | Clinically Isolated Syndrome | Acute Disseminated Encephalomyelitis | NMO Spectrum Disorder | CNS Demyelinating Autoimmune Diseases | Primay Angiitis of the Central Nervous System | Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

China
Haseki Training and Research Hospital

Recruiting

Lidocaine, Dexmedetomidine, Esmolol and Magnesium Effect on Optic Nerve Sheath Diameter After Laryngoscopy

Endotracheal Intubation | Intracranial Hypertension | General Anesthesia | Optic Nerve Sheath Diameter

Turkey
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma. (HBO-RT)

High Grade Glioma | Malignant Glioma | Recurrent Glioma

Italy
Allergan

Completed

Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)

Glaucoma, Open-Angle | Normal Tension Glaucoma

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Completed

Validation of Retinal Oximetry in Glaucoma Patients: a Structural and Functional Correlation

Open Angle Glaucoma | Low Tension Glaucoma

Belgium
CellabMED

Recruiting

A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I)

Recurrent Malignant Glioma

Korea, Republic of
Turku University Hospital

Completed

Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas (RODIG)

Malignant Glioma | Low Grade Glioma

Finland
Tilburg University

Completed

Effects of Exercise on Cognitive Function in Glioma Patients

Low Grade Glioma of Brain | Anaplastic Glioma of Brain

Netherlands
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma

Untreated Childhood Brain Stem Glioma

United States
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Untreated Childhood Brain Stem Glioma

United States
National Cancer Institute (NCI)

Completed

Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma

Untreated Childhood Brain Stem Glioma

United States
Istanbul University - Cerrahpasa (IUC)

Unknown

OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARCİNOMA (ORONIN)

The Aim of Our Study is to Prospectively Evaluate the Optic Neuropathy in Nasopharynx Cancer Patients

Turkey
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Recruiting

Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study

Diabetes Mellitus | Deafness | Ataxia | Diabetes Insipidus | Wolfram Syndrome | Optic Nerve Atrophy

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Recruiting

Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma

Glioblastoma | WHO Grade III Glioma | WHO Grade II Glioma

United States
Phoenix Molecular Imaging

Withdrawn

C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression

Gliomas

United States
Baylor College of Medicine
M.D. Anderson Cancer Center; University of Oklahoma; The University of Texas... and other collaborators

Completed

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Gliomatosis Cerebri | Brainstem Glioma | Malignant Gliomas | Glial Cell Tumors

United States
St. Jude Children's Research Hospital
SpringWorks Therapeutics, Inc.

Recruiting

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Low-Grade Glioma | Recurrent Low-Grade Glioma | Progressive Low-Grade Glioma

United States
University of Chicago

Recruiting

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

Malignant Glioma of Brain

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently

Glioma | Glioma of Brain | Glioma of Spinal Cord

United States, Italy
City of Hope Medical Center
National Cancer Institute (NCI); Food and Drug Administration (FDA)

Active, not recruiting

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Recurrent Glioblastoma | Recurrent Malignant Glioma | Refractory Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Refractory Glioblastoma | Refractory WHO Grade II Glioma | Refractory WHO Grade III Glioma

United States
Qlaris Bio, Inc.

Completed

A Study to Evaluate Safety and Tolerability of QLS-101 in NTG

Normal Tension Glaucoma (NTG)

United States
Zonguldak Bulent Ecevit University

Completed

Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter

Intracranial Pressure Increase | Supraglottic Airway Device | Optic Nerve Sheath Diameter

Turkey
Helsinki University Central Hospital

Recruiting

Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma (ECPNTG)

Cataract | Normal Tension Glaucoma

Finland
Medical University of Vienna

Recruiting

Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

Ocular Hypertension | Glaucoma, Open-Angle | Normal Tension Glaucoma

Austria
Trakya University

Completed

Serum Bilirubin Levels in Normal-tension Glaucoma

Normal Tension Glaucoma | Bilirubin; Defect, Excretion

Turkey

Clinical Trials on Optic Nerve Glioma

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