Clinical Trials on Optic Disk

Total 3519 results

Asan Medical Center
Medtronic

Recruiting

Evaluation of Prevalence and Clinical Impact of Atrial Fibrillation in Elderly Patients With Cryptogenic Stroke and High-Risk Patent Foramen Ovale (DefenseElderly)

Cryptogenic Stroke | High Risk Patent Foramen Ovale

Korea, Republic of
Hospices Civils de Lyon

Recruiting

Pressure and Diabetic Foot (PIV & MPP)

Diabetes and Risk of Diabetic Foot Ulcer

France
Karolinska University Hospital
Umeå University

Enrolling by invitation

Pancreatic Cancer Initial Detection Via Liquid Biopsy (PANCAID)

Pancreatic Cancer | Chronic Pancreatitis | IPMN, Pancreatic | Individuals at Risk

Sweden
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia

B-cell Childhood Acute Lymphoblastic Leukemia | L1 Childhood Acute Lymphoblastic Leukemia | L2 Childhood Acute Lymphoblastic Leukemia | Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia

United States, Canada, Australia, Switzerland
Radboud University Medical Center
Catharina Ziekenhuis Eindhoven

Active, not recruiting

STOP OVarian CAncer; Implementation of the Opportunistic Salpingectomy in the Netherlands (STOPOVCA)

Ovarian Cancer | Risk Reduction

Netherlands
University of British Columbia

Withdrawn

Trial of Local Cystoscopic Injection of Tremelimumab Plus Systemic Durvalumab for High Risk Non-Muscle Invasive Bladder Cancer (Rideau)

Bladder Cancer | High-Risk Cancer | Durvalumab | Non-muscle Invasive | Tremelimumab

Canada
Laboratoire De Recherche Sur Le Diabete, Université...
ATRSS, DGRST, Algeria

Unknown

Covid-19 and Diabetes in West of Algeria (COVIDIAB-13)

Severe Acute Respiratory Syndrome | Coronavirus Infections | Diabetes Mellitus | Prevalence | Risk Factors | Patient Outcome Assessment

Algeria
University Hospital, Clermont-Ferrand

Completed

Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients (PrediRAGE)

Intensive Care Unit | Population at High Risk for ARDS Development

France
Dr Cipto Mangunkusumo General Hospital

Unknown

The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR)

Dry Eye Syndromes | Non-Proliferative Diabetic Retinopathy | Proliferative Diabetic Retinopathy New Vessels on Disc
Oregon Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Enhancing Support for Women at Risk for Heart Disease

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus, Non-insulin Dependent | Coronary Heart Disease Risk Reduction
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Refractory Neuroblastoma | High Risk Neuroblastoma | Resectable Osteosarcoma

United States, Canada
Maastricht University Medical Center

Active, not recruiting

Needs and Preferences of Patients With Head-neck Cutaneous SCC

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Patient Satisfaction | Decision Making | Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer | Preference, Patient | I...

Netherlands
Eurasian Association of Therapists

Completed

Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection (ACTIV-2)

Diabetes | Covid19 | Death | Atrial Fibrillation | Risk Factor, Cardiovascular | CKD | COPD | Comorbidities and Coexisting Conditions | DVT

Russian Federation
Turku University Hospital
University of Turku

Completed

Nutrition and Pregnancy Intervention Study

Liver Diseases | Obesity | Pregnancy | Neurodevelopmental Disorders | Type2 Diabetes | Adiposity | Cardiovascular Risk Factor | Gestational Diabetes Mellitus | Eating Behavior | Cognitive Developmental Disorders

Finland
Sellas Life Sciences Group

Unknown

WT1 Analog Peptide Vaccine in Patients With Multiple Myeloma Following Autologous Stem Cell Transplantation

Multiple Myeloma | Minimal Residual Disease | High-Risk Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome and other conditions

United States
Uskudar State Hospital

Not yet recruiting

Awareness of Osteoporosis in HIV Patients

Osteoporosis | Osteoporosis Risk | Human Immunodeficiency Virus Infection
Atara Biotherapeutics
Memorial Sloan Kettering Cancer Center

Completed

Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma

United States
Kırıkkale University
TC Erciyes University

Not yet recruiting

OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia

Postoperative Complications | Obstructive Sleep Apnea of Adult | Obstructive Sleep Apnea Risk Management | Dental Caries Under General Anesthesia
Oslo University Hospital
University of Oslo; Rigshospitalet, Denmark; University of Oxford; Norwegian SIDS... and other collaborators

Enrolling by invitation

HOME: Home Monitoring of High-risk Pregnancies

Preeclampsia | High Risk Pregnancy | Hypertensive Disorder of Pregnancy | Premature Preterm Rupture of Membranes | Previous Adverse Obstetric Outcome

Norway
Universidad Politecnica de Madrid
Puerta de Hierro University Hospital; Hospital Vall d'Hebron; Hospital Severo... and other collaborators

Recruiting

Active Pregnancy Against COVID-19 (ACPREGCOV)

Pregnancy Complications | Pregnancy, High Risk | Maternal-Fetal Relations | Fetal Growth Retardation | Newborn Morbidity | Weight Gain, Maternal | Pregnancy Induced Hypertension | Fetus Disorder

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Blasts More Than 10 Percent of Bone Marrow Nucleated Cells

United States
Roswell Park Cancer Institute
Celldex Therapeutics

Completed

DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | High Risk Myelodysplastic Syndrome | Refractory Anemia | Blasts 30 Percent or Less of Bone Marrow Nucleated Cells

United States
Columbia University
National Institute of Mental Health (NIMH); Yale University

Completed

Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings

Depression, Anxiety | Human Immunodeficiency Virus | Risk Reduction | Alcohol Abuse | Behavior, Sex

Romania
VASCage GmbH
Medical University Innsbruck; Tirol Kiniken GmbH

Completed

Early Vascular Ageing in the YOUth (EVA4YOU)

Cardiovascular Diseases | Vascular Diseases | Hypertension | Obesity | Overweight | Sleep Disorder | Atherosclerosis | Sleep | Headache | Vascular Stiffness | Cardiovascular Risk Factor | Non-Alcoholic Fatty Liver Disease | Life Style | Cardiovascular Pathology

Austria
University of Latvia
Karolinska Institutet; Lithuanian University of Health Sciences; Technion, Israel... and other collaborators

Completed

Volatile Markers in Digestive Cancer (VOLGACORE)

Gastric Cancer | Colorectal Cancer | Colorectal Adenoma | Intestinal Metaplasia | Atrophic Gastritis | H.Pylori Infection | Peptic Ulcer Disease | Normal Control | Average-risk General Population

Latvia, Lithuania
University of Nebraska

Active, not recruiting

Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors (HBHL)

Lymphoma | Leukemia | Metabolic Syndrome | Osteoporosis | Bone Loss | Pediatric ALL | Acute Lymphoblastic Leukemia, Pediatric | Osteoporosis Risk | Pediatric | Lymphoid Leukemia | Pediatric Lymphoma | Habitual Physical Activity | Precursor Cell Lymphoblastic Leukemia

United States
National Cancer Institute (NCI)

Not yet recruiting

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory High Risk Myelodysplastic Syndrome
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome

United States
University of Modena and Reggio Emilia

Recruiting

Pregnancy Complications in Women With BMI>25 kg/m2 Enrolled in a Healthy Lifestyle and Eating Habits Program (TLC)

Exercise Addiction | Dietary Modification | High-Risk Pregnancy | Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled | Maternal Obesity Complicating Pregnancy, Birth,or Puerperium

Italy
University of Toronto

Unknown

Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk

Cardiovascular Diseases | Stroke | Inflammation | Diabetes | Blood Pressure | Coronary Heart Disease | Adiposity | Cardiovascular Risk Factor | Cholesterol; Lipidosis

Canada
Peking University Third Hospital
Peking University; The First Affiliated Hospital of Anhui Medical University; First Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China (ChiTwiMC)

Pre-Eclampsia | High Risk Pregnancy | Twin Pregnancy, Antepartum Condition or Complication | Pre-Term | Twin Dichorionic Diamniotic Placenta | Twin to Twin Transfusion as Antepartum Condition | Twin Placenta | Twin Monochorionic Diamniotic Placenta

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle Cell | Sickle Cell Cardiopulmonary Complications | Sickle Cell Organ Damage | Sickle Cell Life Expectancy and Risk Factors for Early Death | Sickle Cell Lung Disease and Sudden Death

United States
Microclinic International
Royal Health Awareness Society (RHAS); Jordanian Ministry of Health (MoH)

Completed

Microclinic Social Network Behavioral Health Trial in Jordan

Hyperglycemia | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Body Weight | Weight Loss | Blood Pressure | Weight Gain | Social Behavior | Weight, Body | Glucose, High Blood | Lifestyle, Healthy | Weight Change, Body | Behavior, Health | Lifestyle Risk Reduction | Blood Pressure, High | Hyperglycaemia... and other conditions

Jordan
Alaunos Therapeutics

Completed

A Phase I Trial of ZIO-101 in Hematologic Cancers

Lymphoma | Multiple Myeloma | Acute Leukemia | Chronic Myeloproliferative Disease | Chronic Lymphoproliferative Disease | Poor-risk Myelodysplasia (MDS)

United States
Sue O'Dorisio
National Cancer Institute (NCI); Ride for Kids

Withdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Untreated Childhood Brain Stem Glioma | Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma and other conditions

United States
GT Biopharma, Inc.

Terminated

GTB-3550 Tri-Specific Killer Engager (TriKE®) for High Risk Hematological Malignancies

Acute Myelogenous Leukemia | Systemic Mastocytosis | Mast Cell Leukemia | High-risk Myelodysplastic Syndromes

United States
Maastricht University Medical Center

Recruiting

Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region

Quality of Life | Satisfaction, Patient | Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Squamous Cell Carcinomas | Squamous Cell Carcinoma of the Skin | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer

Netherlands
Teal Health, Inc.

Enrolling by invitation

SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening

HPV Infection | HPV 16 Infection | Hpv | High Risk HPV

United States
Teodoro Marcianò

Terminated

Risk Factors for COVID-19 Mortality (RF-COVID)

Acute Respiratory Distress Syndrome | COVID-19 Virus Infection | Population at Risk

Italy
King Saud University

Completed

Novel Gentic Variations Contributing to Asthma Susceptability in Saudi Arabia

Collection of Clinical Data That Will be Used in This Study and Will Form a Data Bank for Asthma in Saudi Arabia | Identify Known and NOVEL Genetic Risk Factors Contributing to Asthma Susceptibility | Study the Mechanistic Roles of the Genetic Variants Within Major Asthma Susceptibility...

Saudi Arabia
University of California, Davis
National Cancer Institute (NCI); IO Biotech

Recruiting

IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer

Stage 0a Bladder Cancer AJCC v8 | Stage 0is Bladder Cancer AJCC v8 | Stage I Bladder Cancer AJCC v8 | High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma

United States
Herlev and Gentofte Hospital

Recruiting

The Psoriasis Echo Study

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Heart Failure | Stroke | Psoriasis | Heart Failure, Diastolic | Psoriasis Vulgaris | Cardiovascular Risk Factor | Heart Failure, Systolic | Left Ventricular Dysfunction | Psoriasis Universalis | Psoriasis Face | Psoriasis Diffusa | Psoriasis... and other conditions

Denmark
Wroclaw Medical University

Enrolling by invitation

Selected Disorders and Sleep Bruxism

Cardiovascular Diseases | Hypertension | Sleep Apnea | Cardiovascular Risk Factor | Sleep Disorders | Temporomandibular Disorder | Sleep Bruxism | Thyroid Dysfunction | Mental Status Change

Poland
Threshold Pharmaceuticals

Completed

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | High-risk Myelodysplastic Syndrome | Advanced Myelofibrosis

United States
University of Roma La Sapienza

Not yet recruiting

Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs) (CUT-less)

Non-muscle-invasive Bladder Cancer | Non-Muscle Invasive Bladder Urothelial Carcinoma | High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
Jacobs University Bremen gGmbH
Dr. Becker Hospital Group; Dr. Becker Klinik Möhnesee; Dr. Becker Burg-Klinik... and other collaborators

Completed

Feasibility and Benefits of Digital Services During the COVID19 Pandemic (AnhandCOV19)

Anxiety | Communication | Psychological Distress | Health Risk Behaviors | Healthy Lifestyle | Psychological Adjustment | Psychological Stress | Psychological Disorder | Behavior, Health | Psychological Disease | Psychosomatic Disorder | Psychological Adaptation | Health Care Seeking Behavior | Psychological Disability and other conditions

Germany
Wake Forest University Health Sciences

Completed

Habitual Diet and Avocado Trial (HAT)

Cardiovascular Diseases | Diabetes | Metabolic Syndrome | Liver Fat | Cardiovascular Risk Factor | Diet Habit | Dietary Modification | High Cholesterol | Triglycerides High | Low-density-lipoprotein-type | HDL Cholesterol, Low Serum | High Blood Sugar | Intra-abdominal Fat | High Density Lipoprotein Deficiency

United States
CellCentric Ltd.

Recruiting

Study to Evaluate CCS1477 in Haematological Malignancies

Acute Myeloid Leukemia | Multiple Myeloma | Non Hodgkin Lymphoma | Peripheral T Cell Lymphoma | Haematological Malignancy | Higher-risk Myelodysplastic Syndrome

United Kingdom, United States, France, Sweden, Spain
University of Minnesota

Enrolling by invitation

The Professional Peer Resilience Initiative (PPRI)

Stress | Stress, Psychological | Secondary Traumatic Stress | Anxiety | Post Traumatic Stress Disorder | Anxiety State | Stress Disorder | Stress Related Disorder | Trauma, Psychological | Stress Reaction | Professional Quality of Life | Stress Risk | Mental Resilience | Emotional Resilience

United States

Clinical Trials on Optic Disk

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mexico

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations