Clinical Trials on Organ Transplant Rejection in Japan

Total 869 results

Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients (CIRRUS I)

Kidney Transplant Rejection

United States, Hungary, Japan, United Kingdom, Belgium, Spain, Netherlands, Germany, Australia, France, Korea, Republic of, Switzerland, Norway, Italy, Latvia, Sweden, Argentina, Brazil, Canada, Czechia
Astellas Pharma Inc

Completed

A Study to Evaluate Safety and Tolerability of a Therapeutic Vaccine, ASP0113, in Subjects Undergoing Allogeneic Hematopoietic Cell Transplant

Allogeneic Hematopoietic Cell Transplant

Japan
Nippon Kayaku Co., Ltd.

Terminated

Efficacy and Safety of Deoxyspergualin in Renal Transplant Patient With Chronic Rejection

Chronic Rejection

Japan
Yokohama City University Medical Center
Novartis Pharmaceuticals

Unknown

Comparison of the Time to Recurrence Between Ranibizumab and Aflibercept

The Injection Burden

Japan
Showa Inan General Hospital

Completed

The Effectiveness of an Exclusive Cold Snare Polypectomy Snare for the Removal of Diminutive Colorectal Polyps

Postpolypectomy Bleeding | Diminutive Colorectal Polyp | Cold Snare Polypectomy | Polypectomy Snare | Complete Resection Rate

Japan
Shoichi Fujii, MD, PhD

Unknown

Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection

Rectal Cancer | Colon Rectal Resection

Japan
Navitas Life Sciences GmbH
GE Healthcare; Bayer; Guerbet

Completed

Long-Term Retention of Gadolinium in Bone

Focus: Long-term Retention of Gadolinium-based Contrast Agent

Spain, Korea, Republic of, United States, Germany, Japan, Turkey
Fondazione Policlinico Universitario Agostino Gemelli...
Mayo Clinic; Hospital Italiano de Buenos Aires; University of California, Los... and other collaborators

Not yet recruiting

Developing Prediction Models for Allograft Failure After Liver Transplantation (IMPROVEMENT)

Liver Transplant Disorder

United States, Argentina, Brazil, Canada, China, India, Italy, Japan, Netherlands, Spain, United Kingdom
Eli Lilly and Company

Completed

A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

United States, Japan
Ferring Pharmaceuticals

Completed

A Dose-response Trial Using FE 999049 in Japanese Women Undergoing in Vitro Fertilisation (IVF) / Intracytoplasmic Sperm Injection (ICSI) Treatment

Infertility

Japan
Yamaguchi University Hospital

Unknown

Analysis of Implantation Failure and Establishment of Therapy for Implantation Failure

Infertility

Japan
Toray Industries, Inc

Completed

A Pharmacokinetic Study of TRK-100STP in Japanese Patients With Renal Impairment

Renal Impairment

Japan
Novartis Pharmaceuticals

Terminated

An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.

Heart Failure With Preserved Ejection Fraction (HFpEF)

Japan
Bristol-Myers Squibb

Completed

A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function

Heart Failure | Cardiac Failure | Reduced Ventricular Ejection Fraction

United States, United Kingdom, Japan, Netherlands
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
Kyoto University

Completed

Bowel, Urinary and Sexual Function After Laparoscopic Colorectal Surgery

Sexual Dysfunction, Physiological | Colorectal Surgery | Surgery, Laparoscopic

Japan
Nippon Kayaku Co., Ltd.
Shionogi; AEterna Zentaris

Completed

Clinical Pharmacological Study of GnRH Antagonist, Cetrorelix for Healthy Female Volunteer

Premenopause

Japan
Fuji Yakuhin Co., Ltd.

Completed

Clinical Pharmacology of FYU-981 (Subjects With Renal Insufficiency)

Healthy | Renal Insufficiency

Japan
Mitsubishi Tanabe Pharma America

Completed

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment

Healthy | Renal Impairment

Japan
Novartis

Completed

SPP100 (Aliskiren) Regimen in Hypertensive Patients With Renal Dysfunction

Hypertension

Japan
Osaka General Medical Center

Completed

Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection

Emergent Coronary Procedure

Japan
Kissei Pharmaceutical Co., Ltd.

Completed

Late Phase II Clinical Study of KLH-2109 in Patients With Endometriosis

Endometriosis

Japan
Shiga University

Unknown

The Effect of Sacral Surface Electrical Stimulation for Assisted Reproductive Technology (SSE)

Infertility

Japan
Nagano Children's Hospital

Completed

Discharge Criteria of Preterm Infants

Length of Stay

Japan
Tokyo Women's Medical University
Tokyo Metropolitan Bokuto Hospital

Completed

Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia

Hypothyroxinemia

Japan
Sanofi

Completed

Efficacy and Safety of SL77.0499-10 (Alfuzosin) Versus Placebo and Tamsulosin in Japanese Patients With Benign Prostatic Hyperplasia

Prostatic Hyperplasia

Japan
Fuji Yakuhin Co., Ltd.

Completed

Study of FFI-1010 in Pediatric Kidney Disease

Children Under 18 Years Old With Kidney Disease

Japan
Sanofi

Completed

Long Term Safety of SL77.0499-10 (Alfuzosin) in Patients With BPH

Benign Prostatic Hyperplasia

Japan
GlaxoSmithKline

Completed

Bioequivalence Study of Dutasteride Capsules in Healthy Japanese Male Subjects

Prostatic Hyperplasia

Japan
Cytokinetics

Completed

Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection Fraction

Heart Failure With Reduced Ejection Fraction

Japan
Astellas Pharma Inc

Completed

A Study to Investigate the Food Effect on the Pharmacokinetics of YM178 in Healthy, Non-elderly Volunteers

Healthy Volunteer | Pharmacokinetics of YM178

Japan
Sanofi

Completed

PhII One Label Non-Comparative Trial in Metastatic Hormone Refractory Prostate Cancer in Combination With Prednisolone

Prostatic Neoplasms

Japan
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Astellas Pharma Inc

Completed

ASP1517 Pharmacokinetics Study in Anemia Patients on Hemodialysis

Anemia | Hemodialysis | Renal Impairment

Japan
Ferring Pharmaceuticals

Completed

Trial Investigating the Long Term Safety and Tolerability of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Subjects

Nocturia

Japan
Sanofi

Completed

Japanese Study of the Combined Administration of Docetaxel With Prednisolone for Metastatic Hormone Refractory Prostate Cancer

Therapy, Prostatic Neoplasms

Japan
Hamamatsu University

Unknown

Urinary Marker for Oxidative Stress in Human Cisplatin- Induced Renal Injury

Kidney Failure

Japan
Ferring Pharmaceuticals

Completed

Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Male Subjects

Nocturia

Japan
Nara Medical University

Terminated

The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure

Heart Failure | Renal Failure

Japan
Takeda

Completed

Special Drug Use Surveillance of Leuplin PRO for Injection Kit 22.5 mg for "Prostate Cancer"

Prostate Cancer

Japan
Translational Research Center for Medical Innovation...
Jikei University School of Medicine

Completed

PSA Levels and Biopsy Samples After Implant Radiation and Hormone Therapy in Patients With Stage I or Stage II Prostate Cancer (SHIP36B)

Prostate Cancer

Japan
Daiichi Sankyo, Inc.

Completed

A Phase 2 Exploratory Study of CS-3150 in Japanese Hypertensive Patients With Moderate Renal Impairment

Hypertension

Japan
Kissei Pharmaceutical Co., Ltd.
JCR Pharmaceuticals Co., Ltd.

Completed

A Phase III Study of JR-131 in Renal Anemia Patients With Chronic Kidney Disease (CKD)

Anemia

Japan
GlaxoSmithKline

Completed

Immunogenicity and Safety of GSK Biologicals' HPV Vaccine 580299 in Healthy Japanese Females 10-15 Years of Age

Infections, Papillomavirus

Japan
Yokohama City University Medical Center

Completed

Effects of Atorvastatin Versus Probucol on Small Dense LDL

Chronic Nephropathy

Japan
Taro Iguchi, MD, PHD
Astellas Pharma Inc

Completed

Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.

Castration-resistant Prostate Cancer

Japan
Asahi Kasei Pharma Corporation

Completed

Clinical Pharmacokinetics Study of ART-123 in Disseminated Intravascular Coagulation (DIC) Subjects With Renal Impairment

Disseminated Intravascular Coagulation

Japan
Tokyo Women's Medical University

Completed

Bifidobacterium Supplementation for Very Low Birth Weight Infants (Bifido(RCT))

Preterm Infants

Japan
Tokyo Women's Medical University

Completed

Early Administration of Bifidobacterium to Very Low Birth Weight Infants

Preterm Infants

Japan
Ferring Pharmaceuticals

Completed

Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Female Subjects

Nocturia

Japan

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