Clinical Trials on Osteoarthritis; Primary in South Africa

Total 3727 results

University of Birmingham
King's College London; University College, London; University of Nairobi; World... and other collaborators

Completed

A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth (E-MOTIVE)

Post-Partum Haemorrhage

South Africa, Kenya, Tanzania, Nigeria
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Centre for Health Systems Research & Development...
World Bank; Bank-Netherlands Partnership Programme (BNPP)

Unknown

Effective Aids Treatment and Support in the Free State (FEATS) (FEATS)

HIV Infections | HIV/AIDS | Food Insecurity

South Africa
Pacira Pharmaceuticals, Inc

Completed

Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain

Knee Osteoarthritis

United States
Organogenesis
Premier Research Group plc

Active, not recruiting

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
ZARS Pharma Inc.

Completed

Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee

Osteoarthritis

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study

HIV Infection

Malawi, Botswana, South Africa, Zimbabwe
Eli Lilly and Company

Completed

A Study of Duloxetine in Patients With Osteoarthritis Knee Pain

Osteoarthritis Knee Pain

Romania, Spain, United States, Germany, Greece, Puerto Rico, Russian Federation, Sweden
Endo Pharmaceuticals
Medical Research Council; Department for International Development, United...

Completed

Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection

HIV Infections | Gonorrhea | Genital Herpes | Chlamydial Infections

South Africa, Tanzania, Uganda, Zambia
BioCryst Pharmaceuticals

Terminated

BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy (REDEEM-2)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Malaysia, South Africa, Korea, Republic of
ZYUS Life Sciences Inc.
Novotech (Australia) Pty Limited; ZYUS Life Sciences Australia Pty Ltd

Completed

Trichomylin® Safety, Tolerability & Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation (HOPE)

Healthy | Osteoarthritis

Australia
Eccanga Pty Ltd
Syneos Health

Recruiting

FTIH Study of ECC0509 in Healthy Volunteers

Osteoarthritis | Nonalcoholic Steatohepatitis

Australia
HIV Prevention Trials Network

Completed

The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) (ADAPT)

HIV Infections

United States, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immune Response to an HIV Vaccine Boost Following the Administration of Two HIV Vaccines, in HIV-Uninfected, Healthy Adults (Study Extension to HVTN 073/SAAVI 102)

HIV Infections

United States, South Africa
Ferring Pharmaceuticals

Completed

Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Pfizer

Completed

Efficacy and Safety of a Subcutaneous Tanezumab Titration Dosing Regimen in Subjects With Moderate to Severe Osteoarthritis of the Hip or Knee

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Puerto Rico, Canada
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Two HIV Vaccines: SAAVI DNA-C2 Boosted With SAAVIMVA-C, in HIV-Negative Adults

HIV Infections

United States, South Africa
University College, London
M.D. Anderson Cancer Center; National Cancer Institute (NCI); National Institutes... and other collaborators

Recruiting

ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer

Cancer Head Neck | Cancer of Prostate | Cancer Cervix

India, Jordan, Malaysia, South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy

HIV Infections

Malawi, South Africa, India, Tanzania, Thailand
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Active, not recruiting

Mechanisms of Cardiac Dysfunction in HIV and the Effect of Statins: A Cardiac MRI Study

HIV Infections

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female Population

HIV Infections

South Africa, Uganda, Zimbabwe
Lipogems International spa
Alira Health

Recruiting

Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis (ARISE2)

Knee Osteoarthritis | Osteo Arthritis Knee

United States
International Partnership for Microbicides, Inc.

Withdrawn

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa

HIV Infections

South Africa, Kenya, Malawi
Organogenesis

Recruiting

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Pfizer

Completed

Celecoxib Versus Diclofenac In The Treatment Of Osteoarthritis Of The Hip

Osteoarthritis, Hip

United Kingdom
GlaxoSmithKline

Recruiting

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain (MARS-17)

Pain

France, Japan, Spain, China, Korea, Republic of, United States, Argentina, Canada, Germany, South Africa, Australia, Mexico, United Kingdom
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and Postpartum

HIV Infections

Malawi, Zimbabwe, South Africa, Uganda
Pacira Pharmaceuticals, Inc

Completed

Study to Assess the Safety of Repeat Administration of FX006 Administered to Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Pfizer

Terminated

Long-Term Study Of The Safety Of Tanezumab In Arthritis Patients

Osteoarthritis

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)

Osteoarthritis, Knee

United States
Mallinckrodt

Completed

Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis

Osteoarthritis of the Knee

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
Zimmer Biomet
Medical Metrics Diagnostics, Inc; MedNet Solutions

Completed

Subchondroplasty® Knee RCT (PRESERVE Knee)

Osteoarthritis | Knee Osteoarthritis | Osteoarthritis, Knee | Bone Marrow Edema | Knee Pain Chronic

United States, Canada
National Institutes of Health Clinical Center (CC)

Completed

Antiretroviral Therapy for Advanced HIV Disease in South Africa

HIV

South Africa
International Partnership for Microbicides, Inc.

Completed

An Expanded Safety Study of Dapivirine Gel 4789 in Africa

HIV Infections | Acquired Immunodeficiency Syndrome | Healthy

South Africa
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA1)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, Hungary, Spain, Germany, United Kingdom, Denmark, Lithuania, Romania, Russian Federation, South Africa, Ukraine
Wake Forest University Health Sciences
Boston Scientific Corporation

Recruiting

Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy (SASS)

Stress Urinary Incontinence | Pelvic Floor Disorders

United States, South Africa
Genzyme, a Sanofi Company

Completed

Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

Osteoarthritis, Knee

United States, Canada, France, Germany, United Kingdom
Saol Therapeutics Inc

Active, not recruiting

Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain (COMPASS)

Osteoarthritis, Knee Pain

United States
Pacira Pharmaceuticals, Inc

Completed

Study of FX006 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States, Canada, Australia
Sun Pharmaceutical Industries Limited
Moebius Medical Ltd.; Nordic Bioscience Clinical Development (NBCD)

Completed

Efficacy and Safety of MM-II for Treatment of Knee Pain in Subjects With Symptomatic Knee Osteoarthritis

Osteoarthritis of Knee

United States, Denmark, Hong Kong
Fidia Farmaceutici s.p.a.

Completed

Hymovis™ Versus Placebo in Knee Osteoarthritis (Hymovis)

Knee Osteoarthritis

United States, Puerto Rico
Biosplice Therapeutics, Inc.

Completed

A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES-1)

Knee Osteoarthritis

United States
Biosplice Therapeutics, Inc.

Completed

A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis

Knee Osteoarthritis

United States
Pfizer

Terminated

A Long Term Study of the Safety of Tanezumab When Administered By Subcutaneous Injections

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Amgen

Terminated

Study of South African Dialysis Patients

Chronic Kidney Disease, Receiving Dialysis

South Africa
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

Using Nevirapine to Prevent Mother-to-Child HIV Transmission During Breastfeeding

HIV Infections

Zimbabwe, South Africa, Tanzania, Uganda
Taiwan Liposome Company

Completed

Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain (EXCELLENCE)

Osteoarthritis of the Knee

United States, Australia
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety and Efficacy of a Three-Dose Regimen of an Adenoviral HIV Vaccine (MRKAd5 HIV-1 Gag/Pol/Nef) in HIV Uninfected South African Adults

HIV Infections

South Africa
AlphaVax, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); HIV Vaccine...

Completed

Safety of an HIV Vaccine (AVX101) in HIV Uninfected Volunteers in the United States and South Africa

HIV Infections

United States, South Africa

Clinical Trials on Osteoarthritis; Primary in South Africa

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