Clinical Trials on Osteosarcoma

Total 529 results

Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Trastuzumab in Treating Patients With Recurrent Osteosarcoma

Sarcoma

United States
State University of New York - Upstate Medical...

Terminated

Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:

Osteosarcoma | Paget's Disease

United States
Peking University People's Hospital

Unknown

Anlotinib and Irinotecan for Ewing Sarcoma

Ewing's Tumor Metastatic

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma

Sarcoma

United States, Canada, Australia, Puerto Rico
Universitaire Ziekenhuizen KU Leuven

Unknown

Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults (FUBEO)

Osteosarcoma | Ewing Sarcoma

Belgium
M.D. Anderson Cancer Center

Recruiting

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

Soft Tissue Sarcoma | Bone Sarcoma

United States
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas (ImmunoSarc)

Soft Tissue Sarcoma | Bone Sarcoma

Spain, United Kingdom, Italy
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE) (OAIE)

Toxicity | Effect of Drug | Drug

China
Italian Sarcoma Group

Recruiting

Observational Study on Skeletal Ewing's Sarcoma (EWOss)

Ewing Sarcoma of Bone

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna
S. Anna Hospital

Unknown

Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas

Soft Tissue Sarcoma | Ewing

Italy
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression. (PalboSarc)

Osteosarcoma | Chordoma | Soft-tissue Sarcoma

Spain
National University Hospital, Singapore

Unknown

Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas (NKEXPSARC)

Ewing Sarcoma | Rhabdomyosarcoma

Singapore
Pfizer

Completed

Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors

Ewing's Sarcoma Family of Tumors

Spain, France, United States, Italy, Australia, Germany, United Kingdom, Israel, Canada, Brazil, Chile
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Aerosolized Aldesleukin in Treating Patients With Lung Metastases

Sarcoma | Metastatic Melanoma | Metastatic Renal Cell Cancer | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IV Osteosarcoma AJCC v7 | Metastatic Osteosarcoma | Stage IV Renal Cell Cancer AJCC v7 | Metastatic Malignant Neoplasm in the Lung

United States
Institut Curie
UNICANCER

Completed

First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years (CombinaiR3)

Ewing Sarcoma Family of Tumors

France
Istituto Ortopedico Rizzoli
Regione Emilia-Romagna

Completed

Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irinotecan (MGMTLiberati)

Ewing Sarcoma Family of Tumors

United Kingdom, Italy
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Ridaforolimus in Treatment of Sarcoma-SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Ridaforolimus)(8669-011 AM6) (SUCCEED)

Metastatic Soft-Tissue Sarcomas | Metastatic Bone Sarcomas
Medical College of Wisconsin

Recruiting

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Soft Tissue Sarcoma | Osteosarcoma | Chondrosarcoma

United States
M.D. Anderson Cancer Center

Completed

Aerosol L9-NC and Temozolomide in Ewing's Sarcoma

Ewing's Sarcoma

United States
Fudan University

Terminated

Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)

Ewing's Sarcoma

China
Stanford University

Recruiting

Pediatric PET/MR Image Registry

Lymphoma | Osteosarcoma | Soft Tissue

United States
University of Oxford
Astellas Pharma Inc; European Organisation for Research and Treatment of Cancer... and other collaborators

Completed

Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma (LINES)

Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United Kingdom, Germany, Netherlands, Italy, France
National Cancer Institute (NCI)

Terminated

Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma

Sarcoma | Ewing Sarcoma

United States
Massachusetts General Hospital

Completed

Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma

Ewing's Sarcoma

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07)

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions

United States
Ann & Robert H Lurie Children's Hospital of Chicago
On Target Laboratories, LLC

Not yet recruiting

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children (Cytalux)

Osteosarcoma | Pediatrics | Metastatic Sarcoma | Pulmonary Metastasis | Fluorescence
Jazz Pharmaceuticals

Recruiting

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma (EMERGE 101)

Ewing Sarcoma | Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United States, Canada
Centre Leon Berard

Recruiting

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients (REGOMAIN)

Osteosarcoma | Bone Sarcoma

France
University Hospital Muenster

Completed

Study in Localized and Disseminated Ewing Sarcoma (EWING2008)

Ewing's Sarcoma

Germany
National Cancer Institute (NCI)

Completed

A Phase I Study of OncoLAR® (Registered Trademark) (NSC 685403) With/Without Tamoxifen in Patients With Osteosarcoma

Neoplasm Metastasis | Osteosarcoma

United States
Peking University People's Hospital
Shanghai Hansen Biopharmaceutical Technology Co., Ltd; MEDx Translational Medicine...

Recruiting

Soluble B7-H3 as a Biomarker for Osteosarcoma

Progression | Osteosarcoma | Surveillance | Biomarker

China
Italian Sarcoma Group

Completed

Protocol for the Treatment of Metastatic Ewing Sarcoma (EW-2)

Ewing's Sarcoma (ES)

Italy
Power Life Sciences Inc.

Not yet recruiting

Insights Into Participating in Studies for Bone Cancer

Bone Cancer

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma

Lung Metastases | Tumor Necrosis

China
Peking University People's Hospital
Peking University; Northwestern University

Unknown

Epigenetic Biomarker for Advanced Osteosarcoma Using Famitinib and Camrelizumab (EBAOFC)

Drug Resistance to Famitinib and Camrelizumab | Biomarkers for Efficacy and Toxicity

China
National Cancer Institute (NCI)

Completed

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
Centre Antoine Lacassagne

Recruiting

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy (P1V2)

Osteosarcoma | Ewing Sarcoma | Chondrosarcoma | Chordoma

France
Dana-Farber Cancer Institute
1 Million 4 Anna Foundation; Carson Sarcoma Foundation; Teaming up to Fight Childhood... and other collaborators

Completed

Palbociclib + Ganitumab In Ewing Sarcoma

Ewing Sarcoma | Ewing's Sarcoma Recurrent

United States
Asan Medical Center
Novartis

Completed

RAD001 in Advanced Sarcoma

Soft Tissue Sarcomas | Bone Sarcomas

Korea, Republic of
M.D. Anderson Cancer Center
Musculoskeletal Transplant Foundation

Terminated

Retrospective Study of the Biomechanical Properties of Large Allografts

Bone Cancer

United States
Peking University People's Hospital
Peking University Shougang Hospital; Shandong Cancer Hospital and Institute

Recruiting

Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma

Ewing Sarcoma

China
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Sarcoma | Neoplasms, Connective and Soft Tissue | Osteosarcoma | Neoplasms, Connective Tissue | Sarcoma of Bone

Russian Federation
Memorial Sloan Kettering Cancer Center

Recruiting

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

Newly Diagnosed Ewing Sarcoma

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma

Osteosarcoma | Ewing Sarcoma | Paget's Disease

United States
National Cancer Institute (NCI)

Completed

Prognostic Value of a Positive RT-PCR Test in Patients With Ewing Sarcoma

Non-Metastatic Ewings Sarcoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma

United States
GUO WEI

Completed

Apatinib for Advanced Osteosarcoma After Failure of Standard Multimodal Therapy

Osteosarcoma | Metastasis

China
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
Assiut University

Completed

Localized Osteosarcoma in Upper Egypt: A Clinical Prediction Model

Bone Neoplasms

Egypt
Baylor College of Medicine
Cancer Prevention Research Institute of Texas; The Methodist Hospital Research... and other collaborators

Active, not recruiting

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Refractory Neuroblastoma | Uveal Melanoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma | Relapsed Neuroblastoma | Relapsed Rhabdomyosarcoma | Phyllodes Breast Tumor

United States

Clinical Trials on Osteosarcoma

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