Clinical Trials on PI3K Pathway Inhibition
Total 702 results
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AstraZenecaRecruitingLife Threatening Bleeding | Factor Xa InhibitorJapan
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CHU de Quebec-Universite LavalCanadian Institutes of Health Research (CIHR); Laval UniversityCompletedHMG COA Reductase Inhibitor Adverse ReactionCanada
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National Cancer Institute (NCI)Active, not recruitingLow Grade Glioma | Recurrent Visual Pathway Glioma | Refractory Visual Pathway Glioma | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Neurofibromatosis Type 1 | Refractory Neurofibromatosis Type 1United States
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Azafaros A.G.Active, not recruitingNiemann-Pick Disease, Type C | GM2 GangliosidosisBrazil
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Cyclo Therapeutics, Inc.CompletedNiemann-Pick Disease, Type C1United States
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National Institute of Neurological Disorders and...CompletedBrain Neoplasm | Alzheimer's Disease | Niemann Pick DiseaseUnited States
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IntraBio IncCompletedNiemann-Pick Disease, Type CUnited States, United Kingdom, Germany, Slovakia, Spain
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CENTOGENE GmbH RostockCompleted
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KemPharm Denmark A/SCompletedNiemann-Pick Disease, Type CSpain, France, United Kingdom, Switzerland, Denmark, Poland, Italy, Germany
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University of PecsRecruitingWaiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on OutcomesHungary
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Fondazione Policlinico Universitario Agostino Gemelli...WithdrawnCarotid Artery Plaque | Mannose-Binding Lectin Complement Pathway
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St. Jude Children's Research HospitalRecruitingGlioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid AstrocytomaUnited States
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Eunice Kennedy Shriver National Institute of Child...RecruitingNiemann-Pick Disease Type C1 | Juvenile Neuronal Ceroid Lipofuscinosis | Smith-Lemli-Opitz Syndrome | Creatine Transporter DeficiencyUnited States
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Mandos LLCTerminatedNiemann-Pick Disease, Type CUnited States, Australia, United Kingdom, Turkey, Switzerland, Germany, New Zealand, Singapore, France
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National Taiwan University HospitalCompleted
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National Cancer Institute (NCI)CompletedRefractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Brain Stem Neoplasm | Pineal Region Neoplasm | Recurrent Visual Pathway Glioma | Refractory Visual Pathway GliomaUnited States
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Montefiore Medical CenterTerminatedChronic Allograft Injury | Calcineurin Inhibitor ToxicityUnited States
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University Hospital, Clermont-FerrandUnknownCachexia | Cancer of Upper Aerodigestive PathwaysFrance
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WANG Yan-binUnknownIschemic Postconditioning | Ischemia-reperfusion(I/R) | Cardiopulmonarybypass | the Mitochondrial PathwayChina
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Erik MittraNational Cancer Institute (NCI)TerminatedUntreated Childhood Brain Stem Glioma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma and other conditionsUnited States
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Fundación Española de Hematología y HemoterapíaRecruitingNiemann-Pick Diseases | Gaucher Disease | Splenomegaly | Acid SphingoMyelinase Deficiency | ASMDSpain
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Pharvaris Netherlands B.V.RecruitingHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditionsUnited States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
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Indiana Hemophilia &Thrombosis Center, Inc.Active, not recruitingPlasminogen Activator Inhibitor-1 Deficiency | Cardiac FibrosisUnited States
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National Cancer Institute (NCI)CompletedNeurofibromatosis Type 1 | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Childhood Visual Pathway GliomaUnited States, Canada, Australia, New Zealand
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Chinese PLA General HospitalUnknownAdvanced HER-2 Positive Solid Tumors | Chemotherapy Refactory | HER-2 Antibody Inhibitor Therapy RefactoryChina
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King's College LondonCharite University, Berlin, Germany; University Hospital, Bonn; Institut Curie; Levantine UKRecruitingAllergy;Food | Food Allergy Peanut | Pathways and Sources of ExposureUnited Kingdom
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JW PharmaceuticalRecruitingHemophilia A With Inhibitor | Hemophilia A Without InhibitorKorea, Republic of
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Jazz PharmaceuticalsCompletedEvaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...United Kingdom
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Eunice Kennedy Shriver National Institute of Child...RecruitingNiemann-Pick Disease, Type CUnited States
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Eunice Kennedy Shriver National Institute of Child...RecruitingNiemann-Pick Disease, Type CUnited States
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IntraBio IncActive, not recruitingNiemann-Pick Disease, Type CUnited States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
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National Niemann-Pick Disease FoundationIcahn School of Medicine at Mount Sinai; Engage Health Inc.CompletedNiemann-Pick DiseasesUnited States
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Genzyme, a Sanofi CompanyTerminatedNiemann-Pick Disease | Acid Sphingomyelinase DeficiencyUnited States
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Peking University Third HospitalNot yet recruitingAdvanced Solid Tumor | Efficacy | Safety | Stereotactic Body Radiotherapy | Immune Checkpoint InhibitorChina
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University of FreiburgCompletedColitis | Immune Checkpoint Inhibitor-Related ColitisGermany
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Centre Leon BerardMinistry of Health, FranceTerminatedHistologically Confirmed Medulloblastoma | Activation of the Sonic Hedgehog (SHH) PathwayFrance, Italy, Switzerland, United Kingdom
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M.D. Anderson Cancer CenterNot yet recruitingMyeloproliferative Neoplasm | Myelodysplastic Neoplasm | Pathway Mutant Myelodysplastic SyndromesUnited States
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Nanyang Technological UniversityNational Research Foundation, Singapore; Ministry of National Development,... and other collaboratorsRecruitingMental Fatigue | Heart Rate Variability | Working Memory | Cognitive Fatigue | Behavioral Performance | Positive and Negative Affect | Inhibition, Psychological | Perceived RestorationSingapore
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SanofiPulse Infoframe Ltd.RecruitingNiemann-Pick Diseases | Acid Sphingomyelinase DeficiencyUnited States
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Masonic Cancer Center, University of MinnesotaTerminatedSphingolipidoses | Niemann-Pick Disease, Type C | Krabbe Disease | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Hurler's Syndrome | Maroteaux-Lamy Syndrome | Wolman's Disease | Niemann-Pick Disease Type BUnited States
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ZevraDenmarkActive, not recruitingNiemann-Pick Disease, Type CUnited States, Spain, United Kingdom, Denmark, France, Germany, Italy, Poland, Switzerland
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ZevraDenmarkAvailableNiemann-Pick Disease, Type CUnited States
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CENTOGENE GmbH RostockWithdrawnNiemann-Pick Disease, Type C | Niemann-Pick DiseaseGermany, India, Sri Lanka
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Melbourne HealthSanofiWithdrawnLysosomal Storage Diseases | Fabry Disease | Niemann-Pick Disease, Type C | Gaucher DiseaseAustralia
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University Hospital, GrenobleTerminatedPsychiatric Adults PatientsFrance
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Mayo ClinicNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaboratorsCompletedNiemann-Pick Disease, Type CUnited States
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Eunice Kennedy Shriver National Institute of Child...Washington University School of Medicine; University of Oxford; National Human...CompletedNiemann-Pick Disease, Type CUnited States
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Eline C. B. EskesRecruitingAsmd, Visceral TypeNetherlands
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Nanyang Technological UniversityNational Research Foundation, Singapore; Ministry of National Development,... and other collaboratorsRecruitingMental Fatigue | Inhibition | Heart Rate Variability | Working Memory | Cognitive Fatigue | Behavioral Performance | Skin Conductance | Positive and Negative Affect | Perceived RestorationSingapore
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Baodong QinUnknownChemotherapy Effect | Immunotherapy | Tumor Mutation Burden | PD-1/L1 InhibitorChina