Clinical Trials on Pain, During Injection of Propofol for Induction of Anesthesia in South Africa

Total 39 results

Medical University of South Carolina

Terminated

Maternal Epidural Steroids and Hyperthemia

Fever | Labor Pain | Complication of Anesthesia During Pregnancy, Unspecified

United States
Brown University

Active, not recruiting

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Erasmus Medical Center
Elisabeth-TweeSteden Ziekenhuis; Rijnstate Hospital; Red Cross Hospital Beverwijk and other collaborators

Recruiting

Suture Techniques to Reduce the Incidence of Incisional Hernia: LTFU STITCH Trial (LTFU-STITCH)

Quality of Life | Pain | Surgery | Wound Infection | Incisional Hernia | Fascial Dehiscence

Netherlands
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
Ferring Pharmaceuticals

Completed

Misoprostol Vaginal Insert (MVI) 100, 150, 200 mcg for Cervical Ripening and Induction of Labor

Induction of Labor | Cervical Ripening

United States
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
Ology Bioservices

Completed

Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801

Prophylaxis of Ross River Virus Infection

Australia
Ology Bioservices

Completed

Ross River Virus (RRV) Vaccine Study

Prophylaxis of Ross River Virus Infection

Australia
Ferring Pharmaceuticals

Recruiting

REBYOTA™ Prospective Registry (ROAR)

Recurrence of Clostridium Difficile Infection

United States
The University of Queensland
Queensland Children's Hospital; Griffith University; Royal Brisbane and Women... and other collaborators

Recruiting

Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs) (ProP)

Wound Infection | Catheter Infection | Catheter-Related Infections | Wound | Vascular Access Complication | Catheter Complications | Device Related Infection | Wound of Skin | Catheter Related Complication | Device Related Sepsis | Occlusive Dressings | Device Site Reactions

Australia, France
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (PURPOSE 1)

Pre-Exposure Prophylaxis of HIV Infection

South Africa, Uganda
Ferring Pharmaceuticals

Completed

Efficacy & Safety Study Comparing Misoprostol Vaginal Insert (MVI) Versus Dinoprostone Vaginal Insert (DVI) for Reducing Time to Vaginal Delivery (EXPEDITE)

Induction of Labor | Cervical Ripening | Reducing Time to Vaginal Delivery

United States
Medtronic Cardiac Rhythm and Heart Failure

Completed

Micra Transcatheter Pacing Study

Class I or II Indication for Implantation of a Single Chamber Ventricular Pacemaker According to ACC/AHA/HRS 2001 Guidelines and Any National Guidelines

United States, Netherlands, Japan, Serbia, Spain, Greece, Canada, India, Denmark, Czechia, South Africa, Malaysia, Austria, United Kingdom, Hungary, China, Australia, France, Italy
The University of New South Wales
Sydney Children's Hospitals Network; Women's and Children's Hospital, Australia

Completed

Immunogenicity of HPV Vaccine in Immunosuppressed Children

Kidney Transplant Infection | Juvenile Idiopathic Arthritis | Inflammatory Bowel Disease | Autoimmune Disease | Evidence of Liver Transplantation | Bone Marrow Transplant Infection

Australia
MedImmune LLC

Completed

Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults

MEDI3902 for Prevention of P. Aeruginosa Pneumonia

United States
DiaSorin Inc.
ICON Clinical Research

Completed

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects

Nausea | Abdominal Pain | Weight Loss | Helicobacter Pylori Infection | Gastric Ulcer | Stomach Ulcer | Loss of Appetite | Bloating

United States, Italy
Gilead Sciences

Active, not recruiting

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (PURPOSE 2)

Pre-Exposure Prophylaxis of HIV Infection

United States, Thailand, Brazil, Peru, Argentina, South Africa, Mexico, Puerto Rico
GlaxoSmithKline

Completed

Study to Evaluate the Impact of Reactogenicity on Quality of Life (QoL), After Administration of GlaxoSmithKline (GSK) Biologicals' Candidate Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) in Adults ≥ 50 Years of Age

Herpes Zoster

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants (ENSEMBLE)

Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19 at Different Stages of the Protocol

United States, Mexico, South Africa, Brazil, Chile, Colombia, Peru, Argentina
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
MedImmune LLC

Completed

Study of Motavizumab (MEDI-524) and Palivizumab Administered Sequentially in the Same Respiratory Syncytial Virus (RSV) Season

Respiratory Syncytial Virus Infections | Chronic Lung Disease and <= 24 Months of Age or | Premature With Gestational Age <=35 Weeks and <=6 Months of Age

Australia, Chile, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Quality of Life in Children Treated for Cancer

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Diarrhea | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Bacterial Infection | Acute Leukemias of Ambiguous Lineage | Musculoskeletal Complications | Untreated Childhood Acute Myeloid Leukemia...

United States, Canada
Symbollon Pharmaceuticals

Unknown

Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain

Pain | Fibrocystic Disease of Breast | Fibrocystic Changes of Breast | Fibrocystic Mastopathy

United States
University of Alberta

Completed

Acupuncture for Preterm Infants Requiring Eye-exam (MAGNIFIC-ROP)

Pain | Retinopathy of Prematurity | Acupuncture | Premature Infant

Canada, Australia, Malaysia
Zimmer Biomet

Active, not recruiting

Persona Ti-Nidium Post-Market Clinical Follow-up (TKA)

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Patellofemoral Osteoarthritis | Traumatic Arthritis | Varus Deformity | Valgus Deformity | Knee Pain Chronic | Polyarthritis | Flexion Deformity of the Knee

United States
Novartis

Completed

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Pain | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Hypercalcemia of Malignancy

United States
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
US Endoscopy Group Inc.

Completed

trūFreeze® Spray Cryotherapy Patient Registry

Barrett Esophagus | Esophageal Neoplasm | Esophageal Stenosis | Esophageal Dysplasia | Bronchial Neoplasm | Stenosis of Bronchus or Trachea

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Evaluating Dactinomycin and Vincristine in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Ewing Sarcoma of Bone | Ewing Sarcoma | Childhood Acute Lymphoblastic Leukemia | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Rhabdomyosarcoma | Childhood Soft Tissue Sarcoma | Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor...

United States, Australia, Canada

Clinical Trials on Pain, During Injection of Propofol for Induction of Anesthesia in South Africa

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CROs in Germany

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