Clinical Trials on Paraneoplastic Polyneuropathy

Total 557 results

University of Wisconsin, Madison

Completed

MC-5A for Chemotherapy Induced Peripheral Neuropathy

Neuropathy, Paraneoplastic

United States
Pfizer

Completed

The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients

Transthyretin Amyloid Polyneuropathy (ATTR-PN)

China
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Completed

Studies of Neurological Paraneoplastic Syndromes

Paraneoplastic Neurologic Degenerations (PNDs)

United States
German Cancer Research Center
University Hospital Heidelberg; National Center for Tumor Diseases, Heidelberg

Completed

Prevention of Chemotherapy-Related Polyneuropathy Via Sensorimotor Exercise Training (PIC)

Exercise | Chemotherapy-induced Polyneuropathy

Germany
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Improving Mobility in Diabetic Patients Through Resistance Training

Diabetic Patients With Polyneuropathy

Netherlands
Nycomed

Completed

Actovegin® Versus Placebo in Patients With Diabetic Polyneuropathy (AV-007-IM)

Symptomatic Diabetic Peripheral Polyneuropathy

Denmark
Pfizer

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Transthyretin Familial Amyloid Polyneuropathy

Japan
Peking University Third Hospital

Recruiting

The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients

Transthyretin Amyloidosis

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study To Evaluate the Safety, Tolerance, Pharmacokinetics/Pharmacodynamics and Efficacy of SYHA1402 Tablets For the Treatment of Patients With Diabetic Peripheral Neuropathy in China

Distal Symmetric Polyneuropathy (DSPN)
University Health Network, Toronto

Completed

Can Ultrasound Detect Diabetic Peripheral Neuropathy?

Distal Symmetric Polyneuropathy (DSPN)

Canada
Eisai Inc.

Completed

Evaluating the Efficacy and Safety of Oral Ranirestat (40 and 80 mg) in Mild to Moderate Diabetic Sensorimotor Polyneuropathy

Mild to Moderate Diabetic Sensorimotor Polyneuropathy

United States
Vanderbilt University
UCB Pharma

Completed

A Study to Determine if Levetiracetam Will Assist Those Suffering From Chronic Idiopathic Axonal Polyneuropathy.

Chronic Idiopathic Axonal Polyneuropathy

United States
Ionis Pharmaceuticals, Inc.

Recruiting

A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

United States, Italy, Portugal, Spain, Taiwan, Sweden, Canada, Brazil, France, New Zealand, Argentina, Cyprus, Australia, Turkey
Ionis Pharmaceuticals, Inc.

Completed

NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

United States, Spain, Taiwan, Italy, Germany, Argentina, Australia, Brazil, Canada, Cyprus, France, Greece, New Zealand, Portugal, Sweden, Turkey
Eva Pharma
MARC-CRO

Recruiting

Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)

Polyneuropathy, Diabetic

Egypt
University of Kansas Medical Center
Patient-Centered Outcomes Research Institute

Completed

Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS)

Cryptogenic Sensory Polyneuropathy

United States, Canada
Rockefeller University

Completed

The Study of Immune Cell (T Cell) Activity in Patients With Paraneoplastic Neurologic Syndromes

Paraneoplastic Syndromes

United States
Centre Hospitalier Universitaire de Saint Etienne
Laboratoire français de Fractionnement et de Biotechnologies

Completed

Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIg (PRNC)

Demyelinating Polyneuropathy

France
David J. Kopsky
Princess Beatrix Muscle Foundation; Dr. C.J. Vaillant Fonds

Completed

Phenytoin Cream for the Treatment of Neuropathic Pain (EPHENE)

Chronic Idiopathic Axonal Polyneuropathy

Netherlands
Odense University Hospital

Completed

Levetiracetam for Painful Polyneuropathy

Painful Polyneuropathy

Denmark
Peking University Third Hospital

Completed

Methylated DNA Detect in Paraneoplastic Syndrome of Nervous System

Paraneoplastic Neurological Syndrome

China
Vera Bril

Unknown

Panzyga in CIDP Administered at Different Infusion Rates (Panzyga-CIDP)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Canada
University Hospital, Bordeaux

Recruiting

Comparison of FEETME® Soles and GAITRITE® Walkway for the Evaluation of Gait Disorders in CIDP. (ESCAL-PIDC)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

France
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
CSL Behring

Completed

Extension Study of Maintenance Treatment With Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States, Japan, Australia, Canada, Czechia, France, Germany, Italy, Netherlands, Spain, United Kingdom
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

United States
SOM Innovation Biotech SA
Hospital Vall d'Hebron

Completed

Study of SOM0226 in Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy (FAP)

Spain
Institut Mutualiste Montsouris
Assistance Publique - Hôpitaux de Paris; Fondation Paul Bennetot

Unknown

Neuromuscular Electrical Stimulation for Intensive Care Unit-acquired Weakness Assessment (ENS)

Polyneuropathy, Critical Illness

France
Ilko Ilac San. ve Tic. A.S.

Completed

To Assess the Bioequivalence of Test Oral Formulation of Alpha Lipoic Acid 600 mg HR Film Coated Tablets of Ilko Ilac San. Ve Tic. A.S. Versus Reference Thioctacid (Alpha Lipoic Acid) 600 mg HR Film Coated Tablets of Meda Pharma GmbH& CO .KG, Germany.

Peripheral (Sensorimotor) Diabetic Polyneuropathy
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
Henry Ford Health System
Octapharma USA, Inc.

Recruiting

IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies

Small Fiber Neuropathy | Autoimmune Small Fiber Neuropathy | Inflammatory Polyneuropathy | Immune-Mediated Neuropathy

United States
WALA Heilmittel GmbH

Recruiting

Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN

Chemotherapy-induced Polyneuropathy

Germany
WinSanTor, Inc

Completed

A 16-Week Study of Pirenzepine or Placebo to Treat HIV-Associated Distal Sensory Polyneuropathy in Patients With HIV

HIV Associated Polyneuropathy

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP) (BioTRAP)

Transthyretin Amyloidosis | Transthyretin Amyloid Cardiopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

India, Germany
University of Chicago

Terminated

The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy

Idiopathic Axonal Polyneuropathy | Abnormal OGTT

United States
Pfizer

Completed

The Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin Amyloidosis

Transthyretin-associated Amyloidosis With Polyneuropathy

United States, France, Germany, Italy
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Aalborg University Hospital

Recruiting

Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC) (SIDEC)

CIDP - Chronic Inflammatory Demyelinating Polyneuropathy

Denmark
UCB Biopharma SRL

No longer available

CIDP07 Rozanolixizumab Post Trial Access Program (the PTA)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
CSL Behring

Recruiting

Two Dose Levels of Privigen in Pediatric CIDP

Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States
argenx

Completed

A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves) (ADHERE)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States, Austria, Belgium, Bulgaria, China, Czechia, Denmark, France, Georgia, Germany, Hungary, Israel, Italy, Japan, Latvia, Netherlands, Poland, Romania, Russian Federation, Serbia, Spain, Taiwan, Turkey, Ukraine, United Kingdom
argenx

Active, not recruiting

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves) (ADHERE+)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States, Austria, Belgium, Bulgaria, China, Czechia, Denmark, France, Georgia, Germany, Israel, Italy, Japan, Netherlands, Poland, Russian Federation, Serbia, Spain, Ukraine, United Kingdom, Latvia, Romania, Taiwan, Turkey
Shereen Saad Eldin Mohamed Ali

Recruiting

Correlation of HbA1c With Electrophysiological Studies and Gait Performance in Diabetic Polyneuropathy Patients

Diabetic Polyneuropathy

Egypt
Universitair Ziekenhuis Brussel

Completed

VR in Diabetic Polyneuropathy

Diabetic Polyneuropathy

Belgium
Paracelsus Harz Clinic Bad Suderode.

Completed

Study of Physical Therapy in Patients With Diabetic Polyneuropathy

Diabetic Polyneuropathy

Germany
MEDA Pharma GmbH & Co. KG
Quintiles, Inc.; Ergomed; Clinquest, Inc.

Completed

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Diabetic Polyneuropathy (Stage 1 or 2) (NATHAN1)

Diabetic Polyneuropathy

United States, Spain, Croatia, Denmark, France, Italy, Netherlands, Sweden, United Kingdom
Umm Al-Qura University

Completed

Differential Air Pressure Technology for Treatment of Diabetic Elderly Patients

Diabetic Polyneuropathy

Saudi Arabia
Royal Free Hampstead NHS Trust
Bristol-Myers Squibb; Sigma-Tau Research, Inc.

Unknown

ALCAR Prophylaxis Study

HIV Infections | Distal Symmetric Polyneuropathy

United Kingdom
Umm Al-Qura University

Completed

Effects of Antigravity Treadmill Training on Gait and Balance in Patients With Diabetic Polyneuropathy

Diabetic Polyneuropathy

Saudi Arabia
MTI University

Unknown

Effect of Transcranial Direct Current Stimulation on Sensory Integration

Diabetic Polyneuropathy
Medical University of Graz

Completed

Peripheral Nerve Stimulation in Diabetic Patients

Diabetic Polyneuropathy

Austria

Clinical Trials on Paraneoplastic Polyneuropathy

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