Clinical Trials on Part 1 in United Kingdom

Total 2796 results

Manchester University NHS Foundation Trust

Recruiting

Manchester Intermittent and Daily Diet Type 1 Diabetes App Study (MIDDAS-Type 1) (MIDDAS T1)

Obesity | Type 1 Diabetes

United Kingdom
University of California, Irvine
Beckman Laser Institute University of California Irvine

Completed

Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths

Port Wine Stains

United States
Imperial College London

Active, not recruiting

Pancreatic Islet Transplantation to the Anterior Chamber of the Eye (EYELETS)

Type 1 Diabetes | Visual Impairment

United Kingdom
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
Sun Pharma Advanced Research Company Limited

Active, not recruiting

Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies

Healthy (For Part A) | Chronic Myeloid Leukemia (for Part B and C)

United States, Spain, Hungary, Italy, India, Belgium, France, Romania, Singapore, United Kingdom, Korea, Republic of, Turkey
University of Cambridge
Medical University of Graz; Cambridge University Hospitals NHS Foundation Trust and other collaborators

Completed

Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes (AP@home02)

Type 1 Diabetes

United Kingdom, Germany, Austria
Northumbria University
Diabetes UK

Completed

Post-exercise Insulin Reductions in Type 1 Diabetes

Type 1 Diabetes

United Kingdom
Northumbria University

Completed

Guidelines for Post-exercise Dietary Intake in T1DM

Type 1 Diabetes Mellitus

United Kingdom
Cardiff University
Juvenile Diabetes Research Foundation; Diabetes Vaccine Development Centre

Completed

Safety Study to Assess Whether Proinsulin Peptide Injections Can Slow or Stop the Body Damaging Its Own Insulin-making Cells in the Pancreas in Patients Newly Diagnosed With Type 1 Diabetes (MonoPepT1De)

Type 1 Diabetes

United Kingdom
Northumbria University
Newcastle University

Completed

Combined Basal-bolus Insulin and Post-exercise Carbohydrate Feeding Strategy in T1DM

Type 1 Diabetes Mellitus

United Kingdom
Mayo Clinic

Terminated

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

Closed Fracture Proximal Humerus, Four Part

United States
Hoffmann-La Roche

Completed

European, Open-label, Prospective, Multinational, Multicenter Study in Adult Subjects With Type 1 or Type 2 Diabetes Previously on MDI or CSII Therapy. Subjects Home Setting is Considered Routine Practice.

Type 2 Diabetes, Type 1 Diabetes

Austria, United Kingdom
University of Manchester
National Health Service, United Kingdom

Terminated

A Prospective Randomized Controlled Trial to Evaluate the Effectiveness of the Two Different Appliances in the Treatment of Class II Division 1 Malocclusion

Class II Division 1 Malocclusion

United Kingdom
University of Reading
Unilever R&D

Not yet recruiting

Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status

Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota | Focus of Study: 2- Effect of Tea Consumption on Body-iron Status

United Kingdom
University of Pennsylvania

Completed

CART-meso Long-term Follow-up

Subjects Who Have Received Lentiviral-based CART-meso Therapy

United States
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Northern Care Alliance NHS Foundation Trust
Brighter AB

Completed

Actiste® Diabetes Management as a Service (ADMS) Clinical Investigation (ADMSUK01)

Diabetes type1 | Diabetes type2

United Kingdom
PepsiCo Global R&D

Unknown

Plant Based Extracts and Cognition (CEOPTB)

Change in Cognitive Function and Fatigue During Extended Performance of the Cognitive Demand Battery (CDB) at 1, 3 and 6 Hours Post Consumption | Change in Long Term Declarative Memory at 1, 3 and 6 Hours Post-intervention.

United Kingdom
University of California, Irvine
Beckman Laser Institute University of California Irvine

Completed

Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains (PDT/PDL)

Port Wine Stains

United States
Novartis Pharmaceuticals

Withdrawn

ACZ885 in Type 1 Diabetes Mellitus

Diabetes Mellitus | Diabetes Type 1

Germany, United Kingdom, United States, Canada
University of Nottingham
University of Warwick; Loughborough University; Institute of Mental Health Nottingham

Completed

Managing Minds at Work: A Feasibility Pilot Trial

Occupational Stress | Mental Health Wellness 1 | Absence | Sickness Behavior | Occupational Neurosis

United Kingdom
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
Dompé Farmaceutici S.p.A

Completed

Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation (REP0211)

Islet Transplantation in Diabetes Mellitus Type 1

United States, Czechia, Italy, Sweden, United Kingdom
Methodist Health System

Recruiting

Decreasing On-Shift Stress With a Crisis Intervention Cart

Decreasing On-Shift Stress With a Crisis Intervention Cart

United States
Duke University

Completed

Comparison of Topical Skin Adhesive to Subcuticular Suture Closure of Implantable Port Incisions

Port-A-Cath Placement | Octylcyanoacrylate

United States
University of Exeter
King's College London; Benaroya Research Institute; Royal Devon and Exeter NHS...

Recruiting

EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) (EXE-T1D)

Type1 Diabetes Mellitus

Netherlands, United States, United Kingdom
Chelsea and Westminster NHS Foundation Trust

Recruiting

The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers

HIV-1-infection

United Kingdom
East Suffolk and North Essex NHS Foundation Trust
University of Essex

Completed

Impact of Psychological Therapies on Emergency Medical Patients

Mental Health Disorder | Mental Health Wellness 1 | Mental Disorder

United Kingdom
National Institute of Environmental Health Sciences...

Completed

Predictive and Protective Factors in the Cause of Diabetes - A Study in Twins

Diabetes | Type 1 Diabetes

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust

Recruiting

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease (FASTCOPD)

Chronic Obstructive Pulmonary Disease | Alpha 1-Antitrypsin Deficiency

United Kingdom
Imperial College London

Completed

Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis (ALPHA)

Chronic Kidney Diseases | Diabetic Nephropathies | Type 1 Diabetes Mellitus

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Reliability of Functional Outcome Measures in Neurofibromatosis 1: Test- Retest

Neurofibromatosis Type 1

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Reliability of Functional Outcome Measures in Neurofibromatosis 1

Neurofibromatosis 1, NF1

United Kingdom
ANRS, Emerging Infectious Diseases
Imperial College London; University College, London; Fred Hutchinson Cancer Center and other collaborators

Terminated

An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection (EHVAT01)

HIV-1-infection

Switzerland, United Kingdom
King's College London
Diabetes UK; Guy's and St Thomas' Foundation NHS Trust

Completed

A Psychosocial Education Programme for Young People With Type 1 Diabetes - the Youth Empowerment Skills (YES) (YES)

Diabetes Mellitus, Type 1

United Kingdom
Objectif Recherche Vaccins SIDA
Merck Sharp & Dohme LLC; Pfizer; Cytheris SA

Completed

Therapeutic Intensification Plus Immunomodulation in HIV-infected Patients (ERAMUNE-01)

HIV-1 Infection

United Kingdom, France, Italy, Spain
European Organisation for Research and Treatment...
Pfizer

Completed

CREATE: Cross-tumoral Phase 2 With Crizotinib (CREATE)

Locally Advanced and/or Metastatic Anaplastic Large Cell Lymphoma | Locally Advanced and/or Metastatic Inflammatory Myofibroblastic Tumor | Locally Advanced and/or Metastatic Papillary Renal Cell Carcinoma Type 1 | Locally Advanced and/or Metastatic Alveolar Soft Part Sarcoma | Locally Advanced... and other conditions

France, Belgium, Netherlands, Germany, United Kingdom, Italy, Norway, Poland, Slovakia, Slovenia
Homerton University Hospital NHS Foundation Trust

Recruiting

Fathers and Partners in Family Integrated Care Study (TARGET)

Premature Birth | Mental Health Wellness 1

United Kingdom
Novo Nordisk A/S

Terminated

Effect of Insulin Detemir on Use of Energy in Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

United Kingdom
University College, London
National Institute for Health Research, United Kingdom; Myotonic Dystrophy... and other collaborators

Recruiting

Profile of Dysphagia in Myotonic Dystrophy Type 1 (DM1) (SwallowDM1)

Myotonic Dystrophy 1 | Dysphagia, Oropharyngeal

United Kingdom
EarlySense Ltd.

Withdrawn

Evaluation of EverOn™ - A Contact-Free System for Measuring Heart Rate, Respiratory Rate and Motion

Post Surgical Pat., Medical Pat., Resp. Failure, Car.Arrest, Death

United States
Novo Nordisk A/S

Completed

Comparison of Insulin Detemir and NPH With Respect to Lowering the Blood Sugar and Symptoms Experienced by Type 1 Diabetics During Hypoglycaemia

Diabetes | Diabetes Mellitus, Type 1

United Kingdom
University of Oxford

Completed

Investigating Genetic Risk for Type 1 Diabetes (INGR1D)

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease

United Kingdom
University of Cambridge
Cambridge University Hospitals NHS Foundation Trust

Completed

Closing the Loop 24/7 in Adolescents With Type 1 Diabetes (DAN04)

Glucose Metabolism Disorders | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United Kingdom
Sheffield Hallam University
Sheffield Children's NHS Foundation Trust

Completed

Physical Activity Monitoring Paediatric Type 1 Diabetes

Diabetes Mellitus, Type 1

United Kingdom
University College London Hospitals
University College, London; Department of Health, United Kingdom

Completed

Assessment of the Clinical Efficacy and Acceptability of Think Positive (T+) in Diabetes Management (T+)

Diabetes (Insulin-requiring, Type 1 or Type 2)

United Kingdom
Kirby Institute

Completed

MARCH Central Nervous System Substudy

HIV-1 Infection

Argentina, Thailand, United Kingdom
Hull University Teaching Hospitals NHS Trust
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University...

Recruiting

Endoscopic Severity Image Recognition to Advance Research and Training in Inflammatory Bowel Disease (EVEREST - IBD)

Inflammatory Bowel Disease 1

United Kingdom
Boston Scientific Corporation

Completed

Subcutaneous Implantable Defibrillator (S-ICD) System - CE Clinical Investigation

ACC/AHA/NASPE Class 1, IIa or IIb Indications

Netherlands, Italy, United Kingdom, New Zealand
Imperial College London
DexCom, Inc.

Recruiting

RT-CGM in Young Adults at Risk of DKA (YODA)

Glucose Metabolism Disorders | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease

United Kingdom

Clinical Trials on Part 1 in United Kingdom

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