Clinical Trials on Pharmacogenetics in United Kingdom

Total 322 results

Oxford Pharmascience Ltd

Completed

Phase I Study PK Study With OXP005 and Naprosyn

Pharmacokinetics

United Kingdom
Modern Biosciences Ltd

Not yet recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Zentiva, k.s.

Completed

A Study Designed to Evaluate the Pharmacokinetic Profile of Abiraterone

Pharmacokinetics

United Kingdom
UCB Biopharma S.P.R.L.

Completed

Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil

Pharmacokinetics

United Kingdom
Prostrakan Pharmaceuticals

Completed

An Investigation on the Effect of Age and BMI on the Pharmacokinetics of Transdermal Granisetron

Pharmacokinetics

United Kingdom
Xspray Pharma AB

Completed

Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects

Pharmacokinetics | Bioavailability

United Kingdom
Merckle GmbH

Completed

PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants

Pharmacokinetics | Pharmacodynamics

United Kingdom
Oxford Pharmascience Ltd

Completed

Impact of Excipients on Pharmacokinetics of OXPzero(TM) Ibuprofen

Pharmacokinetics

United Kingdom
MediGene

Terminated

Study Evaluating the Pharmacokinetic Profile of RhuDex® in a Tablet Formulation

Pharmacokinetics

United Kingdom
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566.

Pharmacokinetics

United Kingdom
Daiichi Sankyo, Inc.

Completed

Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.

Pharmacokinetics | Tolerability | Safety

United Kingdom
Rock Creek Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Modified and Immediate Release Anatabine Citrate Formulations

Pharmacokinetics of Anatabine

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioactive ASP1707

Pharmacokinetics of ASP1707

United Kingdom
AstraZeneca

Completed

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

Healthy Volunteers | Pharmacokinetics

United Kingdom
Heptares Therapeutics Limited

Completed

Relative Bioavailability of HTL0018318 Oral Aqueous Solution Versus Capsules

Bioavailability and Pharmacokinetics

United Kingdom
Beckley Psytech Limited

Completed

Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
Astellas Pharma Inc

Completed

A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin

Healthy Subjects | Pharmacokinetics | Cardiovascular

United Kingdom
Beckley Psytech Limited

Completed

Single Ascending Dose Study With BPL-003 in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and Tamsulosin

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males

Healthy Subjects | Pharmacokinetics | Tolerability | Safety

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP6294 Administered Intravenously or Subcutaneously in Healthy Young Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP6294

United Kingdom
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP2205 in Healthy Young Males and Females and Elderly Females and to Evaluate the Effect of Food on the Pharmacokinetics of a Single Dose of of ASP2205

Healthy Subjects | Pharmacokinetics of ASP2205

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Multiple Ascending Doses of ASP7962 in Healthy Subjects (MAD)

Healthy Volunteers | Pharmacokinetics of ASP7962

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Clinical Trial to Investigate Safety and Tolerability of ASP7962 in Healthy Humans

Tolerability | Safety | Pharmacokinetics of ASP7962

United Kingdom
AstraZeneca

Completed

Single + Multiple Ascending Dose and Food Effect Study of AZD7986 in Healthy Volunteers, PK, PD and Safety Study

Safety, Pharmacokinetics, Pharmacodynamics, Food Effect

United Kingdom
AstraZeneca

Completed

Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects

Pharmacokinetics | Bioequivalence | Healthy Japanese Subjects

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP3700 in Healthy Male Subjects

Healthy Volunteers | Pharmacokinetics of ASP3700

United Kingdom
Astellas Pharma Europe B.V.

Completed

Drug to Drug Interaction Study With Ipragliflozin and Furosemide

Healthy Subjects | Pharmacokinetics of Ipragliflozin

United Kingdom
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Heptares Therapeutics Limited

Completed

Pharmacokinetics of Oral Capsule in Healthy Japanese vs. Caucasian Subjects (HTL0018318)

Pharmacokinetics | Safety Issues

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905)

Healthy Subjects | Pharmacokinetics | EC905 | Multiple Dose

United Kingdom
Aegerion Pharmaceuticals, Inc.

Completed

Study to Determine the Intra-subject Variability of Pharmacokinetics of Lomitapide in Healthy Subjects

Intra-subject Variability of Pharmacokinetics

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Effect of Race

United Kingdom
Abbott Products
Quintiles, Inc.

Terminated

First in Man Study With SLV342

Pharmacokinetics

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Appearance and Disappearance of ASP3652 in Blood and Spinal Fluid in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

United Kingdom
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmacodynamics of ASP7657 in Caucasian Healthy Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP7657 | Pharmacodynamics of ASP7657

United Kingdom
University Hospital Birmingham NHS Foundation Trust

Completed

Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion

Pharmacokinetics | General Anaesthesia | Propofol | Target Controlled Infusion

United Kingdom
Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...

United Kingdom
University of East Anglia
University of Washington; Fred Hutchinson Cancer Center

Unknown

An Acute Human Intervention With Flavonoid to Investigate Absorption, Metabolism and Excretion (COB)

Pharmacokinetics of Flavonoids in Humans

United Kingdom
AstraZeneca

Withdrawn

A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects

Healthy Male Subjects | Pharmacokinetics | Safety | Food Effect

United Kingdom
Cwm Taf University Health Board (NHS)

Unknown

Clozapine Induced Weight Gain

Weight Gain | Pharmacogenetics | Antipsychotic Agents

United Kingdom
Liverpool Women's NHS Foundation Trust
University of Liverpool

Completed

TINN Pharmacokinetics (PK) Study Treat Infections iN Neonates (TINN-PK)

Pharmacokinetics of Ciprofloxacin in Neonates

United Kingdom
MediGene

Completed

Phase-I Study Evaluating the Pharmacokinetic Profile of RhuDex®

Pharmacokinetics

United Kingdom
AstraZeneca

Completed

Comparison of Two Formulations of AZD5363 and the Effect of Food on Pharmacokinetic Exposure, Safety and Tolerability (OAK)

Safety and Tolerability, | Advanced Solid Malignancy, | Pharmacokinetics, Pharmacodynamics, | Tumour Response,

United Kingdom, Netherlands
Imperial College London

Completed

Beta-lactam Pharmacokinetics in Secondary Care

Pharmacokinetics | Penicillin Allergy | Beta Lactam Adverse Reaction

United Kingdom
University of Washington
Oregon Health and Science University; National Institute of General Medical...

Unknown

Naproxen Pharmacogenetic Study (Project 1, Aim 2)

Pharmacogenetics

United States
AstraZeneca

Completed

Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.

Asthma, | Pharmacokinetics, | Cmax, | Tmax, | λz, | AUC, | Ketoconazole, | Metabolite

United Kingdom
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom

Clinical Trials on Pharmacogenetics in United Kingdom

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