Clinical Trials on Pharmacokinetic

Total 755 results

Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male and Female Subjects of Ascending Multiple Oral Doses of ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

Netherlands
Astellas Pharma Inc
Toray Industries, Inc

Completed

Study to Compare Pharmacokinetic Profiles of TRK-100STP in Japanese, Chinese, and South Korean Non-elderly Healthy Adult Males

Healthy Adult Male | Pharmacokinetics of TRK-100-STP

Japan
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation
Cinclus Pharma AG

Recruiting

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

GERD | Pharmacokinetics | Cardiodynamic ECG | Safety, and Tolerability

Sweden
University of Florida
National Center for Complementary and Integrative Health (NCCIH); Thorne HealthTech...

Completed

A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics (KavaPK)

Pharmacokinetics

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration

Pharmacokinetics | Food-drug Interaction | Ranitidine Adverse Reaction

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Astellas Pharma Global Development, Inc.

Terminated

A Phase 1, Dose Escalation Study to Assess the Safety and Tolerability of ASP9853 With Either Docetaxel or Paclitaxel in Patients With Advanced Non-hematologic Malignancies

Non-hematologic Malignancies | Pharmacokinetics of ASP9853

United States
Boryung Pharmaceutical Co., Ltd

Completed

Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Pharmacokinetics

Korea, Republic of
International Partnership for Microbicides, Inc.

Completed

Expanded Use PK of Dapivirine Vaginal Ring

Pharmacokinetics
Utrecht University

Completed

The Relative Bio-availability of Oral and Oromucosal Melatonin in Different Formulations in Healthy Human Volunteers. (Melaform)

Pharmacokinetics of Melatonin

Netherlands
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Makerere University
Northwestern University

Completed

Antiretroviral Drug Levels During and After Pregnancy

Pharmacokinetics

Uganda
Pfizer

Completed

A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis

Pharmacokinetics | Renal Dialysis

United States
Texas Tech University Health Sciences Center
Merck Sharp & Dohme LLC

Terminated

Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Burns

Burns | Pharmacokinetics

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body

Advanced Solid Tumors | Pharmacokinetics of 14C-OSI-906

United States
Grünenthal GmbH

Completed

Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours

Pain | Pharmacokinetics

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Pharmacokinetics of BAL8728 After a Single Dose of Pyridinylmethyl-14C-Labeled Isavuconazonium Sulfate in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of 14C-labeled Isavuconazonium Sulfate

United States
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Appearance and Disappearance of ASP3652 in Blood and Spinal Fluid in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

United Kingdom
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Multiple-dose Tolerability and Pharmacokinetic Studies of Benapenem in Clinical Healthy Subjects

Multiple-dose Tolerability and Pharmacokinetic Studies of Benapenem in Clinical Healthy Subjects

China
China Medical University Hospital

Unknown

Pharmacokinetic Study of Marine Active in Health Men

Hyperuricemia, Anserine, Pharmacokinetic

Taiwan
University of North Carolina, Chapel Hill
Gilead Sciences

Completed

Single Dose Truvada in HIV-negative Men and Women (TAIL)

Pharmacokinetic Study in Healthy Volunteers

United States
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetic and Tolerability of AP701

Tolerability | Safety | Pharmacokinetic

Germany
Awenydd GmbH

Unknown

Medication Optimisation for Reducing Events in a Private Practice Setting (MORE)

Pharmacogenetic Analysis to Reduce Events.

Germany
Radboud University Medical Center

Not yet recruiting

Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment (MISSION)

Pharmacokinetics | Tacrolimus | Area Under Curve | Immunosuppressive Agents | Mycophenolic Acid
Aelis Farma
European Commission

Completed

AEF0217 First-in-Human Phase I Study in 3 Parts (Single and Multiple Ascending Doses, and Food Effect) in Healthy Subjects. (AEF0217-101)

Safety, Tolerability, Pharmacokinetics of AEF0217

Spain
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans

Healthy Subjects | Pharmacokinetics of 14C-labeled of LXI-15028

China
Astellas Pharma Global Development, Inc.

Completed

Study to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | Pharmacokinetics of 14C-labeled Gilteritinib

United States
AstraZeneca

Completed

Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions

Pharmacokinetics | Relative Bioavailability | AUC | Cmax

United States
University of East Anglia
University of Washington; Fred Hutchinson Cancer Center

Unknown

An Acute Human Intervention With Flavonoid to Investigate Absorption, Metabolism and Excretion (COB)

Pharmacokinetics of Flavonoids in Humans

United Kingdom
The Affiliated Hospital of Qingdao University

Enrolling by invitation

Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects

Pharmacokinetics | Safety

China
University of Hohenheim
German Federal Ministry of Economics and Technology

Completed

Absorption and Excretion Kinetics of the Bioactive Ingredients of Rice Bran Extract

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
Pfizer

Completed

A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents

Pharmacokinetics

United States
Actelion

Completed

Study of Selexipag and Its Metabolite ACT-333679 on Cardiac Repolarization in Healthy Male and Female Subjects

Pharmacokinetics | Tolerability | Safety | Cardiodynamics

United States
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178 Under Fasted and Fed Conditions With One Immediate Release Formulation of YM178 Under Fasted Conditions

Healthy Subjects | Pharmacokinetics of YM178

Netherlands
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

Bioavailability of ASKP1240 in Healthy Subjects After Intravenous and Subcutaneous Administration of ASKP1240

Healthy Volunteers | Pharmacokinetics of ASKP1240 | Pharmacodynamics of ASKP1240

United States
Pfizer

Completed

Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects

Pharmacokinetics | Cytochrome P-450 CYP2D6 | CYP3A4 Protein, Human

United States
Orion Corporation, Orion Pharma

Completed

Pharmacokinetics of Dexmedetomidine During Prolonged Infusion in ICU (DEX PK)

Pharmacokinetics | Sedation

Finland
Chiang Mai University
Thailand Research Fund

Unknown

Itraconazole Pharmacokinetic With and Without Efavirenz Using the Capsule Formulation as Part of Talaromycosis Treatment in HIV-infected Adults (ITRAPK)

Pharmacokinetics | Efavirenz | Penicilliosis

Thailand
Intas Pharmaceuticals, Ltd.
Lambda Therapeutic Research Ltd.

Completed

Comparative, Pharmacokinetic and Pharmacodynamic Study of Subcutaneous Injections of INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.

Pharmacokinetic Bioequivalence Study in Human Healthy Volunteers

India
University of Florida
National Human Genome Research Institute (NHGRI)

Recruiting

Trial of Preemptive Pharmacogenetics in Underserved Patients (ToPP-UP)

Pharmacogenetic Testing | Use of Prescription Medications

United States
Biota Pharmaceuticals, Inc.

Completed

Phase 1 Safety and Pharmacokinetics Study of Single Ascending Doses of BTA-C585 in Healthy Volunteers

Healthy Volunteers | Pharmacokinetics

United States
The Medicines Company

Completed

Appraisal of MDCO-157 and Plavix® Pharmacokinetics and Pharmacodynamics in Healthy Volunteers With an Evaluation (AMPHORE)

Pharmacokinetics and Pharmacodynamics in Healthy Volunteers

France
Fujian Akeylink Biotechnology Co., Ltd.
The First Hospital of Jilin University

Recruiting

Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets

Pharmacokinetics | Food Affect | Single Ascending Dose | Maximum Applicable Dose

China
Dent Neuroscience Research Center

Terminated

Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic Modeling

Central Nervous System Effects of Diphenhydramine | Pharmacokinetics of Diphenhydramine

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
Central South University

Completed

Pharmacokinetics of a Standard Paracetamol Tablet and Oral Solution After Oral Administration in Chinese Healthy Volunteers

Focus of Study: Pharmacokinetics Analysis, in Vivo Dissolution Studies

Clinical Trials on Pharmacokinetic

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