Clinical Trials on Pharmacokinetic

Total 757 results

Astellas Pharma Europe B.V.

Completed

A Clinical Trial to Investigate Safety and Tolerability of ASP7962 in Healthy Humans

Tolerability | Safety | Pharmacokinetics of ASP7962

United Kingdom
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K in Healthy Subjects

Healthy Volunteers | Pharmacokinetics of ASP015K

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

Healthy Subjects | Pharmacokinetics of Isavuconazole

United States
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of ASKP1240 After a Single Intravenous Dose at Escalating Dose Levels in Healthy Subjects

Healthy Volunteers | Pharmacokinetics of ASKP1240

United States
Astellas Pharma Global Development, Inc.

Completed

Study of the Pharmacokinetics of ASP1941 and the Effect on Glucose Concentrations in Male and Female Young and Elderly Healthy Adults

Healthy Volunteers | Pharmacokinetics of ASP1941

United States
Heidelberg University
Sanofi-Synthelabo

Completed

Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 100 μg/ 75 μg Tablets

Pharmacokinetics

Germany
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Bioequivalence Study of the Oral Contraceptive (OC) Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.

Pharmacokinetics | Therapeutic Equivalency | Contraceptives, Oral
AstraZeneca

Completed

Formulation and Food Effect Study of AZD1386 in Healthy Volunteers

Pharmacokinetics
Heidelberg University

Completed

BlueCQ Bioavailability

Pharmacokinetics | Bioavailability | Methylene Blue | Chloroquine
Duke University
National Institute of General Medical Sciences (NIGMS)

Completed

Pharmacogenetic Testing in Primary Care

Pharmacogenetic Testing

United States
Joanneum Research Forschungsgesellschaft mbH

Completed

An Exploratory Study in Healthy Volunteers to Investigate the Cross-talk Between Local Drug Concentrations in the Skin and Systemic Concentrations During Topical Bioequivalence Studies Using Dermal Sampling Techniques

Healthy | Dermal Pharmacokinetic Measurement

Austria
Zhongnan Hospital

Active, not recruiting

Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults

Pharmacokinetic | Abiraterone Acetate | Plasma Concentration | Gene Polymorphism | Metabolic Analysis

China
Cinclus Pharma Holding AB

Completed

Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam

Pharmacokinetics | Safety Issues | Tolerability | Drug Interaction

Sweden
University of Malaya
Ministry of Health, Malaysia

Unknown

Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition

Pharmacokinetics | Molecular Mechanisms of Pharmacological Action

Malaysia
Beijing Tongren Hospital
Grand Pharmaceutical (China) Co., Ltd.

Unknown

Tear Concentrations and Pharmacokinetics of Azithromycin Eye Drops in Healthy Volunteers

Pharmacokinetics

China
Astellas Pharma Europe B.V.
FibroGen

Completed

A Study to Evaluate the Effects of Multiple Doses of FG-4592 on the Exposure, Safety and Tolerability and Effect of Warfarin in Healthy Subjects

Healthy Subjects | Pharmacokinetics of FG-4592

Germany
Astellas Pharma Inc

Completed

Post-marketing Study to Evaluate the Effect of Mirabegron on the Plasma Concentration of Tolterodine

Healthy | Pharmacokinetics of Mirabegron and Tolterodine

Japan
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Safety and Tolerability of YM150 in Healthy Caucasian and Japanese Male and Female Subjects, and to Assess the Effect That Gender May Have on Its Actions in the Body

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Japanese | Caucasian

Germany
Astellas Pharma Inc

Completed

A Study in Healthy Volunteers Comparing Two Different Liquid Formulations of Solifenacin With Each Other and With the Tablet Formulation

Healthy Volunteers | Pharmacokinetics of Solifenacin Succinate

United States
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacodynamics | Pharmacokinetics of ASP015K

United States
Zhe Jiang Hisun Bioray Bio-pharmaceu tical Co.Ltd

Completed

Comparison of Pharmacokinetics and Safety of HS627(2 Specifications) Versus PERJETA With a Single Injection

Similarity of Pharmacokinetics and Safety

China
University of Saskatchewan
Saskatchewan Health Research Foundation; Lung Association of Saskatchewan

Completed

Drug Interaction Study of Apixaban With Cyclosporine or Tacrolimus in Transplant Recipients (ACT-KLR)

Pharmacokinetics | Lung Transplant | Kidney Transplant

Canada
Zhe Jiang Hisun Bioray Bio-pharmaceu tical Co.Ltd

Unknown

Comparison of Pharmacokinetics and Safety of HS632 and Xolair® With a Single Injection

Similarity of Pharmacokinetics and Safety

China
Aegerion Pharmaceuticals, Inc.

Completed

Study to Determine the Intra-subject Variability of Pharmacokinetics of Lomitapide in Healthy Subjects

Intra-subject Variability of Pharmacokinetics

United Kingdom
Astellas Pharma Inc

Completed

Single and Multiple Oral Administration Study of ASP015K in Healthy Nonelderly Volunteers

Healthy Volunteer | Pharmacokinetics of ASP015K

Japan
IVFarma LLC
NADIM LLC

Completed

The Safety and Pharmacokinetics of Primapur and Gonal-f

Pharmacokinetics | Absorption | Area Under Curve

Russian Federation
Bayer

Completed

Rogaratinib (BAY1163877) Human Mass Balance Study

Pharmacokinetics | Clinical Trial, Phase I

Netherlands
Seoul National University Hospital

Completed

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Simvastatin Pharmacokinetics and Gut Microbiome

Korea, Republic of
Wockhardt
Clinartis

Completed

Study to Determine and Compare Plasma and Intrapulmonary Pharmacokinetics of WCK 2349 in Healthy Adult Human Subjects

Intrapulmonary Pharmacokinetics of WCK 2349

United States
KGK Science Inc.
ChromaDex, Inc.

Completed

A Study of the Pharmacokinetics of Three Dosages of Niagen in Healthy Subjects (14NBHC)

Pharmacokinetics

Canada
Astellas Pharma Global Development, Inc.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Fidaxomicin in Healthy Male Japanese and Caucasian Subjects

Healthy Subjects | Pharmacokinetics of Fidaxomicin

United States
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Healthy Subjects | Pharmacokinetics of Mirabegron

Netherlands
Astellas Pharma Inc

Completed

To Evaluate the Effect of Mirabegron (YM178) on Blood Levels of Desipramine When They Are Taken Together

Healthy Subjects | Pharmacokinetics of Mirabegron

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652

United Kingdom
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

Drug-Drug Interaction Study Evaluating Effects of ASP015K on Rosuvastatin

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Explore the Routes of Elimination of MDV3100

Healthy Subjects | Pharmacokinetics of MDV3100

Netherlands
Astellas Pharma Inc

Completed

A Study to Evaluate the Possible Effects of Taking Mirabegron While Taking a Contraceptive Pill

Healthy Volunteers | Pharmacokinetics of Mirabegron

France
Astellas Pharma Inc

Completed

A Study to Evaluate How Mirabegron Enters and Leaves the Bloodstream According to Age and Sex

Healthy Volunteers | Pharmacokinetics of Mirabegron

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization

Healthy Volunteers | Pharmacokinetics of Isavuconazole

United States
Astellas Pharma Inc

Completed

A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Xian-Janssen Pharmaceutical Ltd.

Completed

A Single Dose, Cross-over Bioequivence Study Comparing Galantamine IR (Immediate Release) Table and Galantmine OS (Oral Solution) in Healthy Volunteers

Pharmacokinetics
Astellas Pharma Inc

Completed

A Study to Assess Drug-Drug Interaction Between ASP1941 and Miglitol

Healthy Volunteers | Pharmacokinetics of ASP1941

Japan
Astellas Pharma Inc

Completed

A Study to Compare the Pharmacokinetics of YM150 Formulation-A and Formulation-B

Healthy Volunteer | Pharmacokinetics of YM150

Japan
Astellas Pharma Inc

Completed

A Study to Assess Safety and Tolerability of ASP1941 After Single and Repeated Administration in Healthy Subjects

Healthy Volunteer | Pharmacokinetics of ASP1941

Japan
Norgine

Completed

Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and Cyclosporine

Pharmacokinetics

Bulgaria
Nanjing Zenshine Pharmaceuticals

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetics of ZX-7101A and the Food Effect in Healthy Volunteers

Pharmacokinetics | Tolerance | Safety Issues | Food Effect

China
Frank A. Bucci, Jr., M.D.

Active, not recruiting

Pharmacokinetics of Aqueous Dexamethasone

Pharmacokinetics | Aqueous Dexamethasone | Inflammatory Cytokine Response

United States
Bayer

Completed

Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Subjects

Pharmacokinetics

Germany
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme

Clinical Trials on Pharmacokinetic

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations