Clinical Trials on Pharmacokinetics and Pharmacodynamics

Total 411652 results

Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of Repeat Doses of Rifampin on Mirabegron (YM178) in Healthy Volunteers

Pharmacokinetics of YM178

United States
Astellas Pharma Inc

Completed

To Evaluate the Blood and Urine Concentration and the Safety and Tolerability of Increasing Repeated Doses of Mirabegron (YM178) OCAS in Healthy Young and Elderly Males and Healthy Young and Elderly Females

Healthy Subjects | Pharmacokinetics

Netherlands
AstraZeneca

Completed

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

Healthy Volunteers | Pharmacokinetics

United Kingdom
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB (HTS)

Pharmacokinetics | Efficacy | Safety

China
Factors Group of Nutritional Companies Inc.
Isura

Completed

Pharmacokinetics of Different CoQ10 Formulations

Coenzyme Q10 Pharmacokinetics

Canada
Mahidol University

Active, not recruiting

Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients (PedPK)

Pharmacokinetics | Pharmacogenomics | Oxycodone

Thailand
DSM Nutritional Products, Inc.

Completed

Pharmacokinetic (PK) Evaluation of Bemotrizinol (6%) in a Sunscreen Maximum Usage Trial

Pharmacokinetics | Absorption; Chemicals

United States
Xspray Pharma AB
Axis Clinicals Limited

Completed

Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions

Pharmacokinetics | Drug Interactions

United States
Beijing Continent Pharmaceutical Co, Ltd.

Completed

Study on Pharmacokinetics of Hydronidone

Pharmacokinetics of Hydronidone

China
Dennis Bregner Zetner
Herlev Hospital; Copenhagen University Hospital, Denmark; RepoCeuticals ApS

Completed

Pharmacokinetics of Intravenous, Rectal, Intravesical, Vaginal, and Transdermal Melatonin in Healthy Female Volunteers

Pharmacokinetics | Safety | Melatonin

Denmark
National Institute on Drug Abuse (NIDA)

Completed

Interactions Between Intravenous Cocaine and Acetazolamide or Quinine

Pharmacokinetics | Cocaine Use

United States
The Netherlands Cancer Institute

Completed

Study With Improved Solubility Pazopanib

Pharmacokinetics of Pazopanib

Netherlands
Janssen-Cilag International NV

Completed

A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants

Healthy Volunteers | Pharmacokinetics

Belgium
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Bupivacaine Pharmacokinetics in Ultrasound-guided Axillary Brachial Plexus Block.

Pharmacokinetics | Anesthetics, Local
Sun Yat-sen University

Completed

Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor

Pharmacokinetics | Tolerability | Endostatin

China
Indiana University
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Determine the Effects of Gene Differences and Voriconazole on Enzyme CYP2B6 Activity in the Liver in Healthy Volunteers

Efavirenz, Metabolism and Pharmacokinetics Changes

United States
Pfizer

Completed

A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants

Healthy Volunteers | Pharmacokinetics | Adult

Belgium
Beckley Psytech Limited

Completed

Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects

Pharmacokinetics in Healthy Adults

United Kingdom
Linkoeping University

Completed

Serum Concentrations of Antidepressant Drugs in Pregnant Women - a Naturalistic Study (PAPA)

Pregnancy | Pharmacokinetics | Antidepressive Agents

Sweden
North Carolina Agriculture & Technical State University

Completed

Avenanthramide and Saponin Bioavailability in Oat Bran

Pharmacokinetics | Polyphenols | Human Health
Grünenthal GmbH
Grünenthal, S.A.

Completed

Characterization of the Pharmacokinetics of a Vaginal Ring With 2.0 g Progesterone in Post-menopausal Women

Pharmacokinetics

Mexico
AstraZeneca

Completed

A Study to Assess the Pharmacokinetics and Safety of Single Doses of Anifrolumab in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Safety

United States
China-Japan Friendship Hospital

Unknown

Pharmacokinetics in Extracorporeal Membrane Oxygenation

Extracorporeal Membrane Oxygenation | Pharmacokinetics

China
scPharmaceuticals, Inc.

Completed

Crossover Study to Compare the Pharmacokinetics of Subcutaneous and Intravenous Ceftriaxone Administration

Pharmacokinetics in Healthy Adults
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Astellas Pharma Inc

Completed

Multiple Oral Administration of ASP7991 to Non-elderly Male Subjects

Healthy | Pharmacokinetics of ASP7991

Japan
AstraZeneca

Withdrawn

Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043 (AZD3043)

Pharmacokinetics | Sedation | Tolerability | Safety
Labopharm Inc.

Completed

A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets at Steady State

Healthy Subjects | Pharmacokinetics | Bioavailability
Astellas Pharma Inc

Completed

A Study to Evaluate Safety of Multiple Dose of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Astellas Pharma Inc

Completed

A Safety and Pharmacokinetics Study of ASP0456 in Healthy Subjects

Healthy | Pharmacokinetics of ASP0456

Japan
Astellas Pharma Inc

Completed

A Pharmacokinetic Study to Investigate the Effect of Food on the Pharmacokinetics of YM150

Healthy | Pharmacokinetics of YM150

Japan
Astellas Pharma Inc

Completed

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects

Healthy | Pharmacokinetics of ASP1941

United States
Advenchen Laboratories Nanjing Ltd.

Recruiting

A Study of Diet Influence of AL8326 in Chinese Healthy Adult Subjects

Pharmacokinetics | Diet, High-Fat

China
Drexel University
The Center for Pediatric Pharmacotherapy

Recruiting

Safety and Therapeutic Drug Monitoring of Cefazolin in Continuous Renal Replacement Therapy

Pharmacokinetics | Renal Replacement Therapy

United States
Colorado State University

Completed

Interaction Between Cannabidiol, Meal Ingestion, and Liver Function

Pharmacokinetics | Metabolism | Liver Function

United States
EQRx, Inc.

Completed

To Evaluate the Comparative Pharmacokinetics of Orally Administered EQ143 in Different Racial and Ethnic Populations

NSCLC | Healthy Volunteers | Pharmacokinetics

United States, New Zealand
Akebia Therapeutics

Completed

Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat

Pharmacokinetics | Drug Interaction Potentiation

Canada
Daiichi Sankyo, Inc.

Completed

Effect of Probenecid on Pexidartinib Pharmacokinetics

Pharmacokinetics in Healthy Volunteers

United States
Astellas Pharma Inc

Completed

Study to Evaluate the Effect of Multiple-dose of Fluvoxamine on the Plasma Concentration of Quetiapine (FK949E) in Healthy Male Volunteers

Healthy | Pharmacokinetics of Quetiapine

Japan
Janssen Scientific Affairs, LLC
Bayer

Completed

Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants

Pharmacokinetics | Healthy Participants | Bioavailability

United States
Astellas Pharma Inc

Completed

A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin

Healthy Subjects | Pharmacokinetics | Cardiovascular

United Kingdom
AstraZeneca

Completed

Prilosec Bioequivalence Study in Healthy Volunteers

Bioequivalence, AUC, Cmax, Pharmacokinetics

United States
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of Food on the Absorption, Distribution and Elimination of ASP1941

Healthy | Pharmacokinetics of ASP1941

Japan
Labopharm Inc.

Completed

A Study to Compare the Bioavailability of Two Tramadol Hydrochloride Tablet Products (50 mg and 200 mg, Respectively) at Steady-state Under Fasting Conditions

Healthy Subjects | Pharmacokinetics | Bioavailability
Pfizer

Completed

Open-Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Tamoxifen When Coadministered To Healthy Post-Menopausal Female Subjects

Pharmacokinetics

United States
Baystate Medical Center

Completed

Pharmacokinetics of Oral Thiamine

Pharmacokinetics in Healthy Subjects

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM) /Ethinyl Estradiol (EE) in Healthy Women.

Healthy | Pharmacokinetics | Drug Interactions
Astellas Pharma Inc

Completed

A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers

Healthy | Pharmacokinetics of Atorvastatin

Japan
Astellas Pharma Inc

Completed

A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Enalapril in Healthy Volunteers

Healthy | Pharmacokinetics of Enalapril

Japan
Norgine
Quotient Sciences

Completed

A Pharmacokinetic Study of PLENVU® in Healthy Subjects (PKPU)

Pharmacokinetic

United Kingdom

Clinical Trials on Pharmacokinetics and Pharmacodynamics

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