Clinical Trials on Pharmacokinetics in Healthy Young Men

Total 670 results

Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4 | Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19...

United Kingdom
Central South University

Completed

Pharmacokinetics of a Standard Paracetamol Tablet and Oral Solution After Oral Administration in Chinese Healthy Volunteers

Focus of Study: Pharmacokinetics Analysis, in Vivo Dissolution Studies
Vernalis (R&D) Ltd

Completed

Single and Multiple Ascending Dose Study of V158866 in Healthy Volunteers

First in Man Study

United Kingdom
University of Oxford
Mahidol University; Mahidol Oxford Tropical Medicine Research Unit

Recruiting

Pharmacokinetic Study of Artemether-lumefantrine and Amodiaquine in Healthy Subjects (ALAQ)

Healthy | Pharmacokinetic | Drug Combination

Thailand
Everstar Medicines (Shanghai) Limited

Completed

A Study of Ralinepag in Healthy Chinese Adult Subjects

Healthy Volunteer | Pharmacokinetic Study

China
Joanneum Research Forschungsgesellschaft mbH

Completed

An Exploratory Study in Healthy Volunteers to Identify Factors Influencing Bioequivalence Studies on Moderately Lipophilic Drugs Using Dermal Open Flow Microperfusion (dOFM)

Healthy | Dermal Pharmacokinetic Measurements

Austria
Federal University of Rio Grande do Sul

Completed

Pulsed Current Versus Russian Current Effects in Healthy Young Subjects.

Healthy Young | Electric Stimulation Therapy

Brazil
King's College London

Completed

Palmitic Acid in the Sn-2 Position of Triacylglycerols and Postprandial Lipemia

Healthy Men | Raised Fasting Plasma Triacylglycerol Concentrations

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905)

Healthy Subjects | Pharmacokinetics | EC905 | Multiple Dose

United Kingdom
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
Astellas Pharma Inc

Completed

A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus

Healthy | Pharmacokinetics of ASP015K and Tacrolimus

United States
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Warfarin in Healthy Male Subjects

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of S- and R-warfarin | Pharmacodynamics of Warfarin

United States
Maastricht University Medical Center
Wageningen University

Completed

GOS and Microbial Fermentation in Aging

Healthy Young Adults | Prefrail Elderly

Netherlands
University of Oxford
Mahidol University; Mahidol Oxford Tropical Medicine Research Unit

Terminated

Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Subjects (ALAQPQ)

Healthy | Pharmacokinetic | Drug Combination

Thailand
Milton S. Hershey Medical Center

Completed

Influence of Selenium on Prostate Cancer Related Biomarkers

Effect of Selenium on Oxidative Stress in Healthy Men

United States
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomedica; Fundació Institut de Recerca de... and other collaborators

Unknown

Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers (APSEP)

Healthy | Pharmacogenetics

Spain
Lundquist Institute for Biomedical Innovation at...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Project 1: Diet and Exercise Modulate the Sperm Epigenome in Men

Obese | Healthy Lifestyle | Men

United States
Saglik Bilimleri Universitesi

Not yet recruiting

Effectiveness of Distal and Proximal Muscle Fatigue for Healthy Young Adults

Healthy | Fatigue | Young Adult

Turkey
Astellas Pharma Inc

Completed

A Study to Assess Drug Interaction of ASP015K and Midazolam

Healthy | Pharmacokinetics of ASP015K and Midazolam

United States
Turtle Health, Inc.

Completed

Evaluation of New Semen Collection & Transportation Kit

Sperm Parameters in Fertile and Infertile Men

United States
AstraZeneca

Completed

Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK

Healthy Volunteers Pharmacokinetic Study

United Kingdom
Astellas Pharma Inc

Completed

A Study to Investigate the Effect of YM150 on the Plasma Concentration of Digoxin in Healthy Subjects

Healthy | Pharmacokinetic of Digoxin

France
Yiling Pharmaceutical Inc.

Completed

A Phase I Pharmacokinetics Study for KT07 Capsule

Pharmacokinetics | Healthy Adult Subjects | Safety and Tolerability

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Astellas Pharma Global Development, Inc.

Completed

A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K

Healthy Volunteers | Pharmacokinetics of ASP015K | Food Effect

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Effect of Race

United Kingdom
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Corporacion Parc Tauli

Completed

Gender Differences in Social Cognition in Patients With Schizophrenia of Recent Diagnosis and Healthy Controls Subjects

Healthy Men | Healthy Women | Women With Recent Diagnosis of Schizophrenia | Men With Recent Diagnosis of Schizophrenia

Spain
North Carolina Agriculture & Technical State University

Completed

Avenanthramide and Saponin Bioavailability in Oat Bran

Pharmacokinetics | Polyphenols | Human Health
Acibadem University
Istanbul University

Completed

Perturbation Based Neuromuscular Training Effects on Peroneal Strength, Fatigue and Functional Performance Parameters

Basketball Players | Healthy Young Women

Turkey
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labeled Prodrug Isavuconazonium Sulfate (BAL8557) in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of 14C-labeled Isavuconazole

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
North Carolina Agriculture & Technical State University

Completed

Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human

Pharmacokinetics | Polyphenols | Human Health

United States
Washington University School of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement (RLICC)

Healthy, Young Adults

United States
Università degli Studi 'G. d'Annunzio' Chieti e...

Completed

Pharmacological Cognitive Enhancement (MODREST)

Fluid Inteligence | Modafinil | Healthy Young Subjects | Resting State Networks

Italy
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Vanda Pharmaceuticals

Completed

Evaluation of the Pharmacodynamic and Pharmacokinetic Interactions of Tasimelteon and Ethanol

Pharmacodyamics and Pharmacokinetics of Tasimelteon Alone and in Combination With Ethanol

Canada
Alessandro Haupenthal
Santa Catarina Federal University

Completed

Analysis of the Effects on Human Tissues After Application of Therapeutic Modalities.

Health | Young Adults | Humans

Brazil
Astellas Pharma China, Inc.

Completed

A Study to Investigate the Effect of Food With Mirabegron in Healthy Chinese Participants

Pharmacokinetics of Mirabegron | Food Effect | Healthy Chinese Subjects

China
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

Healthy Subjects | Pharmacokinetics
Astellas Pharma Global Development, Inc.
Yale University

Completed

A Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP3662

Healthy Volunteers | Pharmacokinetics of ASP3662 | Displacement of Radiotracer

United States
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmacodynamics of ASP7657 in Caucasian Healthy Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP7657 | Pharmacodynamics of ASP7657

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male and Female Subjects of Ascending Multiple Oral Doses of ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

Netherlands
Astellas Pharma Inc
Toray Industries, Inc

Completed

Study to Compare Pharmacokinetic Profiles of TRK-100STP in Japanese, Chinese, and South Korean Non-elderly Healthy Adult Males

Healthy Adult Male | Pharmacokinetics of TRK-100-STP

Japan

Clinical Trials on Pharmacokinetics in Healthy Young Men

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