Clinical Trials on Pharmacokinetics of Melatonin

Total 27222 results

The Affiliated Hospital Of Guizhou Medical University

Not yet recruiting

Population Pharmacokinetic Study of the Effect of Polymorphisms in the ABCB1 and CES1 Genes on the Pharmacokinetics of Dabigatran

Combined Analysis of Polymorphisms and Dabigatran Pharmacokinetic Parameters
Astellas Pharma Global Development, Inc.

Recruiting

A Study to Assess the Antitumor Activity, Safety, Pharmacokinetics and Biomarkers of Zolbetuximab (IMAB362) in Participants With Claudin (CLDN) 18.2 Positive, Metastatic or Advanced Unresectable Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma (ILUSTRO)

Gastric Cancer | Pharmacokinetics of Zolbetuximab | Gastro-esophageal Junction (GEJ) Cancer | Pharmacokinetics of Oxaliplatin | Pharmacokinetics of Fluorouracil Bolus (5-FU)

United States, Japan, Italy, Korea, Republic of, Taiwan, France
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom
Vanda Pharmaceuticals

Completed

Evaluation of the Pharmacodynamic and Pharmacokinetic Interactions of Tasimelteon and Ethanol

Pharmacodyamics and Pharmacokinetics of Tasimelteon Alone and in Combination With Ethanol

Canada
Inonu University
The Scientific and Technological Research Council of Turkey

Unknown

Endogenous Melatonin Levels on Anxiety in Living Liver Donors

Liver Transplantation | Anxiety | Melatonin

Turkey
Columbia University

Terminated

Pharmacokinetics of Intranasal Ketorolac in Children

Pain | Evaluating Pharmacokinetics of Intranasal Ketorolac

United States
Shanghai Vinnerna Biosciences Co., Ltd.

Active, not recruiting

Effect of Pharmacokinetics in Healthy Chinese Subjects

The Effects of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects

China
Liverpool Women's NHS Foundation Trust
University of Liverpool

Completed

TINN Pharmacokinetics (PK) Study Treat Infections iN Neonates (TINN-PK)

Pharmacokinetics of Ciprofloxacin in Neonates

United Kingdom
Tel Aviv University

Completed

Melatonin Production Delay in Preterm Infants

Melatonin Production

Israel
Turku University Hospital

Completed

Bioavailability of Intranasal Dexmedetomidine (INDEX)

Pharmacokinetics | Anesthesia | Arthritis Knee | Arthritis of Hip

Finland
Yuhan Corporation

Completed

A Phase 1 Clinical Trial to Investigate Pharmacokinetics and Drug Interaction of Crestor and Glucodown OR SR in Healthy Volunteers

Pharmacokinetics and Drug Interaction of Crestor and Glucodown SR

Korea, Republic of
Sihuan Pharmaceutical Holdings Group Ltd.

Unknown

Multiple-dose Tolerability and Pharmacokinetic Studies of Benapenem in Clinical Healthy Subjects

Multiple-dose Tolerability and Pharmacokinetic Studies of Benapenem in Clinical Healthy Subjects

China
Astellas Pharma Inc

Completed

A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K

United States
Medical University of Lodz

Completed

Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia

Melatonin Deficiency

Poland
Astellas Pharma Inc

Completed

A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K

United States
Chung Shan Medical University

Not yet recruiting

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects

Taiwan
Astellas Pharma Inc

Completed

A Single and Multiple Oral Dose Study and a Treatment Schedule-finding Study in Non-elderly, Healthy Subjects

Pharmacokinetics of ASP3325 in Non-elderly, Healthy Adult Japanese Male and Female, and Caucasian Male Subjects

Japan
AstraZeneca

Completed

A Study of Fostamatinib in Subjects With Impaired Hepatic (Liver) Function

Healthy Volunteers | Pharmacokinetics | Hepatic Impairment | Amount of R406 in Blood

United States
National Yang Ming University

Completed

Tryptophan Supplementation to Improve Night Shift Workers' Health

Burnout | Sleep | Mood | Melatonin Deficiency | Cortisol Deficiency

Taiwan
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate a Single Intravenous (IV) Dose Using a New Manufactured Clone and Single Ascending Doses of Subcutaneous (SC) Injections

Healthy Subjects | Pharmacokinetics of ASP2408

United States
AstraZeneca

Completed

To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594

Pharmacokinetics | Safety | Pharmacodynamics of AZD7594

United Kingdom
Astellas Pharma Inc

Completed

A Study to Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult Volunteers

Healthy Subjects | Pharmacokinetics of YM178

United States
Astellas Pharma China, Inc.

Completed

A Study to Compare How Tamsulosin is Absorbed to the Body After Administration of Two Types of Tamsulosin Formulation Under Fed and Fasted Conditions in Chinese Healthy Subjects

Healthy | Pharmacokinetics of Tamsulosin Hydrochloride

China
Francesca Garofoli
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia; IRCCS...

Completed

Oral Melatonin as Neuroprotectant in Preterm Infants

Malondialdehyde | Melatonin

Italy
University of Southern Denmark
Region of Southern Denmark

Completed

The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1

Pharmacogenetics of Metformin

Denmark
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Natural Immune Systems Inc

Recruiting

Immunological Effect of Increasing Doses of Natural Peptide

Pharmacokinetics

United States
Natural Immune Systems Inc

Recruiting

Clinical Study on Rapid Antioxidant Protection and Immune Modulating Effects.

Pharmacokinetics

United States
Second Affiliated Hospital of Wenzhou Medical University
Wanbangde Pharmaceutical Group Co., LTD

Not yet recruiting

Study on the Pharmacokinetics of Bromine Hexane Hydrochloride Tablets in Healthy Adults

Pharmacokinetics
Rennes University Hospital

Recruiting

P-glypoprotein Inhibition Effect on the Pharmacokinetics of Two Tacrolimus Formulations: Prolonged and Extended-release (DIPLOID)

Pharmacokinetics

France
Shanghai Mabgeek Biotech.Co.Ltd
The Second Hospital of Anhui Medical University

Active, not recruiting

Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Healthy Adult Subjects

Pharmacokinetics

China
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function

Pharmacokinetics

United States
XBiotech, Inc.

Active, not recruiting

Hutrukin to Analyze Safety and PK in Healthy Volunteers

Pharmacokinetics

United States
Guangdong Raynovent Biotech Co., Ltd

Completed

Mass Balance Study of [14C]ZSP1273 in Healthy Adult Male Subjects in China

Pharmacokinetics

China
Alumis Inc

Completed

Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants

Pharmacokinetics

United States
Journey Medical Corporation
Dr. Reddy's Laboratories Limited

Completed

A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects

Pharmacokinetics

Canada
BHB Therapeutics, Ireland LTD
Mérieux NutriSciences Biofortis

Completed

Pharmacokinetics of C6 Ketone Di-ester

Pharmacokinetics

United States
Wockhardt

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Oral WCK 2349

Pharmacokinetics
SoVarGen Co., Ltd.

Completed

Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults

Pharmacokinetics

Korea, Republic of
PepsiCo Global R&D

Completed

Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States

Pharmacokinetics

United States
Joint Stock Company "Farmak"

Completed

Fasting Bioequivalence Study of 2 Oral Progesterone Soft Capsules 200 mg in 48 Healthy Female Subjects

Pharmacokinetics

Jordan
Joint Stock Company "Farmak"

Completed

Fasted Bioequivalence Study of Clopidogrel Film-coated Tablets, 75 mg in 48 Healthy, Adult Male and Female Subjects.

Pharmacokinetics

Ukraine
Joint Stock Company "Farmak"

Completed

Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting Condition

Pharmacokinetics
Joint Stock Company "Farmak"

Completed

Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene

Pharmacokinetics

United States
Guerbet

Completed

Pharmacokinetics and Safety of Gadopiclenol in Japanese Healthy Volunteers

Pharmacokinetics

Japan
Centre hospitalier de l'Université de Montréal...

Completed

Peak Plasma Levels of Bupivacaine After a Pecto-Intercostal Fascial Block Post-Sternotomy for Cardiac Surgery

Pharmacokinetics

Canada
Philip Morris Products S.A.

Completed

Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it

Pharmacokinetics

Russian Federation
Scynexis, Inc.
Clinical Network Services (CNS) Pty Ltd

Completed

Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects

Pharmacokinetics

Australia
University of Alberta

Completed

Ketone Levels Achieved After Medium Chain Triglyceride (MCT) Oil

Pharmacokinetics

Canada

Clinical Trials on Pharmacokinetics of Melatonin

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