Clinical Trials on Pharmacokinetics of Oxaliplatin

Total 27415 results

Amphastar Pharmaceuticals, Inc.

Completed

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers

Pharmacokinetics | Pharmacodynamics

United States
Hospital Clinic of Barcelona
University of Barcelona

Completed

Pharmacokinetic Model of Fibrinogen Plasma Levels After Fibrinogen Administration (PKMF)

Fibrinogen; Deficiency, Acquired | PHARMACOKINETICS

Spain
Pfizer

Completed

Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML

Pharmacokinetics | Safety | ECG

Canada, Spain, United States, Hungary, Poland, United Kingdom
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

Healthy Subjects | Pharmacokinetics
National Institute of Mental Health (NIMH)

Completed

Evaluation of a Novel PET Radioligand to Image OGA

Pharmacokinetics | Adult

United States
University of Hohenheim

Completed

Comparison of Curcumin Bioavailability

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
University of Hohenheim

Completed

Bioavailability of Resveratrol From Vineatrol30 Extract Incorporated Into Micelles

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
AstraZeneca

Completed

A Drug-Drug Interaction Study to Study the Effect of AZD1981 on Warfarin

Pharmakokinetic

Sweden
Soonchunhyang University Hospital

Unknown

Attenuated SOX as First-line Treatment in Elderly Patients With Relapsed or Metastatic Gastric Cancer

Gastric Cancer | Elderly | Oxaliplatin | S-1 | First-Line
Geropharm

Recruiting

Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141

Pharmacokinetics | Pharmacodynamics | Bioequivalence

Russian Federation
Cinclus Pharma AG

Recruiting

A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

GERD | Pharmacokinetics | Cardiodynamic ECG | Safety, and Tolerability

Sweden
University of Florida
National Center for Complementary and Integrative Health (NCCIH); Thorne HealthTech...

Completed

A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics (KavaPK)

Pharmacokinetics

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration

Pharmacokinetics | Food-drug Interaction | Ranitidine Adverse Reaction

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Boryung Pharmaceutical Co., Ltd

Completed

Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects

Pharmacokinetics

Korea, Republic of
International Partnership for Microbicides, Inc.

Completed

Expanded Use PK of Dapivirine Vaginal Ring

Pharmacokinetics
Makerere University
Northwestern University

Completed

Antiretroviral Drug Levels During and After Pregnancy

Pharmacokinetics

Uganda
Pfizer

Completed

A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis

Pharmacokinetics | Renal Dialysis

United States
Duke University
National Institute of General Medical Sciences (NIGMS)

Completed

Delivery of Pharmacogenetic Testing in a Community Pharmacy Setting

Pharmacogenetics

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Unknown

Dose-dense Biweekly Docetaxel, Oxaliplatin and 5-fluorouracil as First-line Treatment in Advanced Gastric Cancer (DaeMon-Plus)

Docetaxel, Oxaliplatin and Fluorouracil

China
Blokhin's Russian Cancer Research Center

Recruiting

FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma (RusGCG-01)

Stomach Neoplasms | Gastrointestinal Neoplasms | Docetaxel | Oxaliplatin | Fluoruracil | Irinotecan Hydrochloride

Russian Federation
University Medicine Greifswald

Not yet recruiting

Impact of Food Intake on Berberine Kinetics (BERKI-3)

Pharmacokinetic Study in Healthy Volunteers

Germany
University Medicine Greifswald

Recruiting

Sex Differences in Berberine Pharmacokinetics (BERKI-2)

Pharmacokinetic Study in Healthy Volunteers

Germany
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
AstraZeneca

Completed

Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK

Healthy Volunteers Pharmacokinetic Study

United Kingdom
AstraZeneca

Completed

Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Capsules Relative to That From Co-administration of ABT-335 and Rosuvastatin for the 5/45mg Dosage Form.

Adverse Events | Pharmacokinetic Variables

United States
Texas Tech University Health Sciences Center
Merck Sharp & Dohme LLC

Terminated

Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Burns

Burns | Pharmacokinetics

United States
Grünenthal GmbH

Completed

Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours

Pain | Pharmacokinetics

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Pharmacokinetics | EC905

United Kingdom
West Virginia University

Completed

Effect of Body Mass on Acyclovir Pharmacokinetics

Hematological Malignancy | Pharmacokinetics of Acyclovir

United States
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 New Tablet Versus Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

Pharmacokinetic Study Comparing Blood Levels of Dasatinib in Healthy Participants Who Received the Tablet Formulation With Those Who Received Liquid and Tablet-dispersed Formulations

Pharmacokinetic Study in Healthy Participants

United States
Radboud University Medical Center

Not yet recruiting

Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment (MISSION)

Pharmacokinetics | Tacrolimus | Area Under Curve | Immunosuppressive Agents | Mycophenolic Acid
AstraZeneca

Completed

Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions

Pharmacokinetics | Relative Bioavailability | AUC | Cmax

United States
The Affiliated Hospital of Qingdao University

Enrolling by invitation

Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects

Pharmacokinetics | Safety

China
University of Hohenheim
German Federal Ministry of Economics and Technology

Completed

Absorption and Excretion Kinetics of the Bioactive Ingredients of Rice Bran Extract

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
Pfizer

Completed

A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents

Pharmacokinetics

United States
Actelion

Completed

Study of Selexipag and Its Metabolite ACT-333679 on Cardiac Repolarization in Healthy Male and Female Subjects

Pharmacokinetics | Tolerability | Safety | Cardiodynamics

United States
Pfizer

Completed

Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects

Pharmacokinetics | Cytochrome P-450 CYP2D6 | CYP3A4 Protein, Human

United States
Orion Corporation, Orion Pharma

Completed

Pharmacokinetics of Dexmedetomidine During Prolonged Infusion in ICU (DEX PK)

Pharmacokinetics | Sedation

Finland
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomedica; Fundació Institut de Recerca de... and other collaborators

Unknown

Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers (APSEP)

Healthy | Pharmacogenetics

Spain
Nerre Therapeutics Ltd.

Completed

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Pharmacokinetic Study in Healthy Male Volunteers

United Kingdom
Lupin Ltd.

Completed

Two Way Cross Over BE Fasting Pilot Study of Ropinirole Hydrochloride CR 2mg Tablets

Pharmacokinetic Study

India
Astellas Pharma Inc

Completed

To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their Effects

Healthy Subjects | Pharmacodynamic and Pharmacokinetic Interaction

France
Chiang Mai University
Thailand Research Fund

Unknown

Itraconazole Pharmacokinetic With and Without Efavirenz Using the Capsule Formulation as Part of Talaromycosis Treatment in HIV-infected Adults (ITRAPK)

Pharmacokinetics | Efavirenz | Penicilliosis

Thailand
University Medicine Greifswald

Completed

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers (BERKI-1)

Pharmacokinetic Study in Healthy Volunteers

Germany
Presidio Pharmaceuticals, Inc.

Completed

A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and Omeprazole

Pharmacokinetic Assessments in Healthy Volunteers

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
Astellas Pharma Inc

Completed

Examination of Plasma Concentrations and Safety in Chronic Kidney Disease Patients Undergoing Hemodialysis

Patients on Stable Chronic Maintenance Dialysis Who Are Receiving Hemodialysis Therapy | Pharmacodynamics of ASP7991 | Pharmacokinetics of ASP7991

Japan

Clinical Trials on Pharmacokinetics of Oxaliplatin

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