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Clinical Trials on Phase I: Relapsed or Refractory B-cell Malignancies
Total 574 results
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University of PennsylvaniaCompletedAdult Patients Who Have Relapsed or Refractory CLL (3rd Line) or SLLUnited States
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Fred Hutchinson Cancer Centermedac GmbHRecruitingAcute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mantle Cell Lymphoma | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Prolymphocytic Leukemia | Refractory... and other conditionsUnited States
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Alexion Pharmaceuticals, Inc.No longer availableNon-hodgkin's Lymphoma | Relapsed/Refractory Chronic Lymphocytic Leukemia
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedPrimary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditionsUnited States
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedPrimary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditionsUnited States
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Janssen Biotech, Inc.Pharmacyclics LLC.Approved for marketingRelapsed or Refractory Mantle Cell LymphomaUnited States, Brazil, Puerto Rico
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AmgenNot yet recruitingB Precursor Acute Lymphoblastic Leukemia | Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
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Swiss Group for Clinical Cancer ResearchActive, not recruitingLeukemia | Chronic Lymphocytic Leukemia | Relapsed/Refractory Chronic Lymphocytic LeukemiaSwitzerland
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Yale UniversitySidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Massey Cancer CenterWithdrawnLymphoma | Relapsed and Refractory Aggressive B- and T-cell LymphomasUnited States
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Mundipharma Research LimitedInnovative Therapies For Children with Cancer ConsortiumTerminatedRelapsed or Refractory T-cell Acute Lymphoblastic Leukaemia | B-cell Precursor Acute Lymphoblastic Leukaemia | T-cell Non-Hodgkin's LymphomaCzech Republic, Austria, France, Germany, Italy, United Kingdom
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Ono Pharmaceutical Co. LtdRecruitingRelapsed or Refractory T Cell LymphomaUnited States
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Memorial Sloan Kettering Cancer CenterUniversity of NebraskaCompletedT-cell Lymphomas | Relapsed or RefractoryUnited States
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Affiliated Hospital to Academy of Military Medical...Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Peking...RecruitingAge Range ≥16 Years, Gender Unlimited | Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma | Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed | At Least One Positive Lesion According to the 2014... and other conditionsChina
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US Oncology ResearchEli Lilly and CompanyCompletedRelapsed or Refractory Mantle Cell Lymphoma (MCL)
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedAcute Myeloid Leukemia | Hodgkin Lymphoma | Recurrent Hodgkin Lymphoma | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Myelodysplastic Syndrome and other conditionsUnited States
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M.D. Anderson Cancer CenterNot yet recruitingB-cell Acute Lymphocytic Leukemia | Relapsed/RefractoryUnited States
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Bristol-Myers SquibbRecruitingRelapsed or Refractory T-cell LymphomasJapan
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Masonic Cancer Center, University of MinnesotaActive, not recruitingFollicular Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma | Hodgkin Lymphoma | Lymphoplasmacytic Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Bone Marrow Failure Syndromes | Burkitt's Lymphoma | Acute Lymphoblastic Leukemia... and other conditionsUnited States
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Masonic Cancer Center, University of MinnesotaRecruitingLymphoma | Follicular Lymphoma | Acute Myeloid Leukemia | Multiple Myeloma | Myelofibrosis | Juvenile Myelomonocytic Leukemia | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Acute Leukemia | Mantle-Cell Lymphoma | Chronic Myelogenous... and other conditionsUnited States
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)CompletedHIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditionsUnited States
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TakedaCompletedRelapsed or Refractory CD30+ Hodgkin's Lymphoma or Anaplastic Large Cell LymphomaJapan
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Tesaro, Inc.CompletedChronic Lymphocytic Leukemia | Solid Tumors | T-cell-prolymphocytic Leukemia
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)TerminatedStage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse... and other conditionsUnited States
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City of Hope Medical CenterNational Cancer Institute (NCI)CompletedFollicular Lymphoma | Diffuse Large B-Cell Lymphoma | Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Myeloproliferative... and other conditionsUnited States
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Great Novel Therapeutics Biotech & Medicals CorporationRecruitingRelapsed or Refractory Peripheral T-cell LymphomaTaiwan
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Kura Oncology, Inc.CompletedRelapsed or Refractory Peripheral T-Cell LymphomaUnited States, Spain, Korea, Republic of
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Shanghai YingLi Pharmaceutical Co. Ltd.UnknownRelapsed or Refractory Peripheral T-Cell LymphomaChina
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Samsung Medical CenterCompletedRelapsed or Refractory Peripheral T-cell LymphomaKorea, Republic of
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Institut de Recherches Internationales ServierRecruitingMyelodysplastic Syndromes | Relapsed or Refractory Acute Myeloid Leukemia (AML) | Untreated AML | Other IDH1-mutated Positive Hematologic MalignanciesUnited States, France
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National Cancer Institute (NCI)TerminatedNodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditionsUnited States
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BeBetter Med IncCompletedRelapsed or Refractory Multiple Myeloma | Relapsed or Refractory Non-Hodgkin's LymphomaChina
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University of Medicine and Dentistry of New JerseyNational Cancer Institute (NCI)WithdrawnRecurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditionsUnited States
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SymBio PharmaceuticalsCompletedAssess the Efficacy and Safety of SyB L-0501 in Combination With Rituximab in Patients With Recurrent or Relapsed DLBCLJapan
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Sun Yat-sen UniversityRecruitingRelapsed or Refractory Peripheral T-cell LymphomaChina
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Dizal PharmaceuticalsCompletedRelapsed or Refractory Peripheral T Cell LymphomaKorea, Republic of, United States, China, Australia
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Jennifer R. Brown, MD, PhDAstraZeneca; TG Therapeutics, Inc.Active, not recruitingChronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Relapsed Chronic Lymphocytic LeukemiaUnited States
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Chia Tai Tianqing Pharmaceutical Group Co., Ltd.TerminatedRelapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChina
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National Cancer Institute (NCI)TerminatedUnspecified Childhood Solid Tumor, Protocol Specific | Peripheral T-cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Childhood Chronic Myelogenous Leukemia | Cutaneous B-cell Non-Hodgkin Lymphoma | Hepatosplenic T-cell Lymphoma | Intraocular Lymphoma | Recurrent Childhood Acute Lymphoblastic... and other conditionsUnited States, Canada
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Acrotech Biopharma Inc.Axis Clinicals LimitedCompletedRefractory Peripheral T-Cell Lymphoma | Relapsed Peripheral T-Cell LymphomaUnited States
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CSPC ZhongQi Pharmaceutical Technology Co., Ltd.UnknownRelapsed or Refractory Peripheral T-cell and NK/T-cell LymphomaChina
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Zhejiang Genfleet Therapeutics Co., Ltd.RecruitingRelapsed or Refractory Peripheral T-cell Lymphoma (PTCL)China
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Aibin Liang,MD,Ph.D.CARsgen Therapeutics Co., Ltd.RecruitingRelapsed and/or Refractory Multiple Myeloma | Plasma Cell Leukemia in RelapseChina
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Queen Mary University of LondonGilead SciencesUnknownRecurrent or Refractory B Cell Acute Lymphoblastic LeukaemiaUnited Kingdom
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First Affiliated Hospital of Harbin Medical UniversityUnknownCD19-chimeric Antigen Receptor T Cells | Relapsed and/or Refractory Acute Lymphoblastic Leukemia | the Haploidentical Hematopoietic Stem Cell TransplantationChina
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Memorial Sloan Kettering Cancer CenterRecruitingNon-Hodgkin Lymphoma | Non-Hodgkin's Lymphoma, Relapsed | Non-Hodgkin's Lymphoma RefractoryUnited States
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AmgenAmgen Astellas Biopharma K.K.CompletedRelapsed Refractory B Precursor Acute Lymphoblastic LeukemiaJapan
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National Cancer Institute (NCI)CompletedHIV Infection | Clear Cell Renal Cell Carcinoma | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditionsUnited States
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AmgenActive, not recruitingRelapsed or Refractory Multiple Myeloma | Relapsed or Refractory Acute Myeloid LeukemiaUnited States, Australia, Japan, Germany, Canada
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Vincerx Pharma, Inc.TerminatedChronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Relapsed Non Hodgkin Lymphoma | Richter Syndrome | MYC Amplification | MYC Overexpression | MYC TranslocationUnited States, Poland
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Wake Forest University Health SciencesNational Cancer Institute (NCI)CompletedPrimary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditionsUnited States