Clinical Trials on Physiologic Effects of Drugs

Total 2483 results

Hospital Ruber Internacional

Recruiting

Galactose Supplementation for the Treatment of MOGHE (GATE)

Refractory Epilepsy | SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation

Spain
National Taiwan University Hospital

Unknown

Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis

Chronic Graft Versus Host Disease | Sjogren Syndrome | Mucous Membrane Pemphigoid | Cicatrizing Conjunctivitis | Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | Chemical Burn to Eye

Taiwan
Medical University of Lodz

Completed

Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis

Myocardial Infarction | Ischemic Stroke | Endocarditis | Patent Foramen Ovale | Embolic Stroke of Undetermined Source | Atrial Fibrillation and Flutter | Cardiac Tumor
University College, London

Recruiting

Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping (PC-TOX)

Cardiovascular Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Cardiotoxicity | Malignancy | Oesophagus Cancer | Fluorouracil Adverse Reaction

United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity | Breast Cancer Stage IV | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-positive Metastatic Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma (T-Cell #4)

Lymphoma | Leukemia | Cardiac Toxicity
Mina Wageh Mohareb
Al-Azhar University

Recruiting

Individualized and Combined Effects of Diabetes and Smoking on the Antiplatelet Activity of Ticagrelor in Acute Myocardial Infarction Patients Undergoing Primary PCI

Individualized and Combined Effects of Smoking and Diabetes on the Antiplatelet Activity in Patients Undergoing Primary Percutaneous Coronary Intervention

Egypt
Istanbul University - Cerrahpasa (IUC)

Recruiting

Elastographic Improvement of Vaginal Atrophy Treated by Erbium Yag Laser

Vaginal Atrophy | Dyspareunia | Laser | Genitourinary Syndrome of Menopause (GSM)

Turkey
Ewha Womans University Seoul Hospital
Ewha Womans University Mokdong Hospital; National Rehabilitation Center, Seoul...

Recruiting

The Efficacy and Feasibility of Smartphone-Based Speech Therapy for People With Post-Stroke Dysarthria

Dysarthria as Late Effect of Stroke

Korea, Republic of
Cairo University

Recruiting

Piezo-surgical Implant With Laser

Effect of Piezo-surgical Implant With Laser on Pain and Swelling in Patients With Missing Teeth

Egypt
Hunan Cancer Hospital

Recruiting

Anti-PD-1 Antibody Combined With Peg-Asparaginase and Chidamide for the Early Stage of NK/T Cell Lymphoma

Chemotherapy Effect | NK/T-cell Lymphoma of Nasal Cavity | Immune Checkpoint Inhibitor | Epigenetic Disorder

China
Imperial College London
University of Aberdeen

Completed

Metastatic Prostate Cancer Men's Attitudes Towards Treatment of the Local Tumour and Metastasis Evaluative Research (IP5-MATTER)

Quality of Life | Surgery | Patient Satisfaction | Health Care Utilization | Prostate Cancer Metastatic | Radiotherapy Side Effect | Urologic Cancer

United Kingdom
University of Michigan
U.S. National Science Foundation

Recruiting

Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis (RB)

Opioid Use Disorder | Alcohol Use Disorder | Health Risk Behaviors | Criminal Behavior | Overdose of Opiate | Housing Problems

United States
Centre hospitalier de l'Université de Montréal...
Fonds de la Recherche en Santé du Québec

Terminated

Comparison of OraQuick HCV Rapid Antibody Test and Standard Serologic Screening for Hepatitis C: Validity, Acceptability and Impact on Linkage to Care

Active or Ex-injection Drug Users | Indication of Hepatitis C Screening

Canada
Assiut University

Not yet recruiting

Predictors of Aortic Root Dilatation in Tetralogy of Fallot Patients

Tetralogy of Fallot | Congenital Heart Disease | Aortic Root Dilatation
Institut National de la Santé Et de la Recherche...
UPCET; PARTNERS for International clinical Research; European Fundation for the... and other collaborators

Active, not recruiting

Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen (TREOCAPA)

Acetaminophen | Patency of the Ductus Arteriosus | Extreme Prematurity

France, Norway, Belgium, Estonia, Ireland, Switzerland, Sweden, Denmark, Finland, Hungary, Italy, Portugal
Indonesia University

Completed

Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery

Myocardial Injury | Cardiac Surgery

Indonesia
University of Zurich

Completed

Cardiac Computed Tomography: Characteristics of Isolated Left Ventricular Non-compaction

Left Ventricular Noncompaction | Isolated Noncompaction of the Ventricular Myocardium

Switzerland
Ewha Womans University Seoul Hospital
Ewha Womans University Mokdong Hospital; National Rehabilitation Center, Seoul...

Not yet recruiting

The Effectiveness of Smartphone-Based Speech Therapy for People With Post-Stroke Dysarthria

Dysarthria as Late Effect of Stroke
Qin Ning

Recruiting

A Prospective/Retrospective, Observational Follow-up Study of Chronic Hepatitis B With Non-alcoholic Fatty Liver Disease.

the Effect of NAFLD on CHB

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs

Nausea | Vomiting | Head and Neck Squamous Cell Carcinoma | Radiotherapy Side Effect

China
Taiwan Adventist Hospital

Completed

Investigating Program of Food Preparation on Diet Improvement for Patients With Stroke

Stroke | Dysphagia, Late Effect of Stroke

Taiwan
Zhongshan Bo Ai Hospital

Completed

The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome

The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group; | At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether; | 534... and other conditions

China
Hasselt University
Jessa Hospital; Ziekenhuis Netwerk Antwerpen (ZNA); Ziekenhuis Oost-Limburg; Algemeen... and other collaborators

Recruiting

HCV Reinfection After DAA Therapy in PWID in Belgium (REINF_HCV)

Drug Use | Hepatitis C Virus Infection, Response to Therapy of

Belgium
University of Sao Paulo

Not yet recruiting

Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization (LBIARHMI)

Molar Incisor Hypomineralization
Institut National de la Santé Et de la Recherche...

Recruiting

Long Term Follow-up of the TREOCAPA Study (TREOCAPA-LT) (TREOCAPA-LT)

Patency of the Ductus Arteriosus Acetaminophen Extreme Prematurity

France
AO Innovation Translation Center

Recruiting

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection

Mandibular Reconstruction | Segmental Mandibular Defects

Germany, Switzerland, United States, Netherlands, Sweden, Spain
Steven M Levy

Active, not recruiting

Iowa Fluoride Study/Iowa Bone Development Study ((IFS/IBDS))

Dental Caries | Bone Density | Dental Fluoroses
Liaoning Tumor Hospital & Institute

Not yet recruiting

Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection

Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer
First Hospital of Zhangjiakou City

Completed

Impact of External Drainage of the Lumbar Cistern in Patients With Hydrocephalus Following Meningioma Surgery and Its Influence on Patient Satisfaction

Investigate the Effect of External Lumbar Cistern Drainage in Preventing Postoperative Hydrocephalus in Patients Who Have Undergone Meningioma Surgery

China
Rigshospitalet, Denmark

Completed

Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions

Liver Diseases | Heart Failure | Quality of Life | Kidney Diseases | Cancer | Pulmonary Disease | Neurologic Disorder | Side Effect | Physical Disorder

Denmark
University of Aarhus

Unknown

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection. (TSCORII)

Hypertension | Ischemic Heart Disease | Aortic Aneurysm | Turner Syndrome | Congenital Heart Defect

Denmark
Tulane University
Louisiana State University Health Sciences Center in New Orleans; Antares Pharma...

Not yet recruiting

Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis

Multiple Sclerosis | Erectile Dysfunction | Testosterone Deficiency

United States
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
Rachel Miller
Office of US Army Medical Research and Material Command

Completed

Chemotherapy-Induced Cognitive Impairment in Ovarian Cancer Patients

Chemotherapy-induced Cognitive Impairment

United States
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
Tehran University of Medical Sciences

Unknown

Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence

Tumor | Tethered Cord Syndrome | Fibrolipoma of Filum Terminale | Lipomyelomeningocele | Split Cord Malformation | Dermal Sinus

Iran, Islamic Republic of
Sun Yat-sen University

Recruiting

Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.

Non-small Cell Lung Cancer | Cardiac Toxicity

China
Military Institute of Medicine, Poland

Recruiting

Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy

Non-small Cell Lung Cancer | Radiation Toxicity | Cardiac Toxicity

Poland
Dana-Farber Cancer Institute
AstraZeneca

Withdrawn

Cardiotoxicities in Patients Receiving BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors (SENTINEL)

Hypertension | Atrial Fibrillation | Chronic Lymphocytic Leukemia | Cardiotoxicity

United States
University Medicine Greifswald

Recruiting

Effect of Glass-Ionomer Sealing Technique on Hypersensitive Teeth With Molar Incisor Hypomineralisation (MIH_GIC)

Molar Incisor Hypomineralization | Hypersensitive | Pit and Fissure Sealants

Germany
Nemours Children's Clinic
Thomas Jefferson University

Recruiting

Contrast Enhanced Three Dimensional Echocardiographic Quantification of Right Ventricular Volumes in Repaired Congenital Heart Disease

Tetralogy of Fallot | Pulmonary Insufficiency

United States
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Incontinence and Quality of Life in Children With Spina Bifida

Myelomeningocele | Spina Bifida

United States
Odense University Hospital

Recruiting

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Quality of Life | Pleural Carcinomatosis | Chemotherapy Effect | Pleural Neoplasms | Chemotherapeutic Toxicity | Malignant Pleural Effusion | Pleural Cavity Effusion

Denmark
Klinikum Nürnberg

Recruiting

A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease. (DapaBalci-Leap)

Chronic Renal Failure | Mechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis

Germany, France
Sun Yat-sen University

Recruiting

Detecting Chemosensitivity and Predicting Treatmemt Efficacy With CTCs in mNPC

Nasopharyngeal Carcinoma | Circulating Tumor Cell | Effects of Chemotherapy | Distant Metastases.Clinical

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Culturally Adapted Parenting Intervention for Spanish-Speaking Parents in Improving Outcomes of Younger Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia Survivors at Risk for Late Neurocognitive Effects

Childhood Acute Myeloid Leukemia in Remission | Cancer Survivor | Childhood Acute Lymphoblastic Leukemia in Remission | Cognitive Side Effects of Cancer Therapy

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Enrolling by invitation

Sexuality and Sexual Quality of Life in Adult Patients With Turner Syndrome (TS) Compared With Patients With Primary Ovarian Insufficiency Different From TS (SEXATURN)

Primary Ovarian Insufficiency | Turner Syndrome

France

Clinical Trials on Physiologic Effects of Drugs

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