Clinical Trials on Polybrominated Biphenyl Poisoning

Total 561 results

Medical University of South Carolina
UCB Pharma

Withdrawn

Efficacy of Keppra in Acute Alcohol Related Seizure Control--A Pilot Study

Seizure, Alcohol Related

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Cancer and Leukemia Group B

Terminated

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Colorectal Cancer | Neurotoxicity | Cognitive/Functional Effects
OHSU Knight Cancer Institute
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Terminated

Neurotoxicity in Primary Central Nervous System Lymphoma (PCNSL): An International Observational Study of Cognition in Long Term Survivors

Primary Central Nervous System Lymphoma (PCNSL)

United States, Germany
Second Affiliated Hospital of Nanchang University

Unknown

Clarify of Predictive Risk Factors of Chemotherapy-induced Liver Injury

Liver Injury, Drug-Induced

China
Northwestern University

Terminated

D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain

Pain | Breast Cancer | Neurotoxicity

United States
University Hospital, Montpellier

Completed

Magnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity Syndrome (MR-ICANS)

Lymphoma, B-Cell | Neurotoxicity

France
Merck Sharp & Dohme LLC

Terminated

Study of Preladenant for the Treatment of Neuroleptic Induced Akathisia (Study P05145)

Movement Disorders | Antipsychotic Agents | Akathisia, Drug-Induced
Universitaire Ziekenhuizen KU Leuven

Unknown

Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective Study

Sarcoma, Soft Tissue | Osteosarcoma Tumor

Belgium
UCB Pharma

Completed

Levetiracetam in the Treatment of Neuroleptic-induced Tardive Dyskinesia

Dyskinesia, Medication-induced

Belgium, Bulgaria
University of Nottingham
Nottingham University Hospitals NHS Trust; Ipsen; National Institute for Health... and other collaborators

Recruiting

Drug-induced Liver Injury: Itching Study

Pruritus | Drug Induced Liver Injury

United Kingdom
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Lymphoma | Neurotoxicity | Therapy-related Toxicity

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Chemotherapeutic Agent Toxicity

United States, Israel
University of York
Medical Research Council

Completed

A Clinical Study to Develop an Uninfected Sand Fly Biting Protocol (FLYBITE)

Leishmaniasis, Cutaneous | Insect Bites

United Kingdom
Mode Sensors AS
Oslo University Hospital

Recruiting

Detecting Fluid Accumulation With a Wearable Bioimpedance Sensor (DELOS)

Edema | Kidney Failure | Overhydration

Norway
Essentia Health

Completed

Treating Alcohol Withdrawal With Oral Baclofen

Alcohol Withdrawal Delirium

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Observational Study of Exposure to Environmental Toxicants Among Firefighters

Healthy

United States
Northside Hospital, Inc.

Recruiting

Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States
AHS Cancer Control Alberta
Cross Cancer Institute

Withdrawn

A Trial of Glutamine to Prevent Oxaliplatin Neurotoxicity and a Pharmacokinetic Analysis of Oxaliplatin

Colorectal Cancer | Metastasis | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome | Water Intoxication | Water-electrolyte Imbalance

Germany
Far Eastern Memorial Hospital

Unknown

Cutaneous Denervation in Alcoholic Neuropathy

Peripheral Neuropathy | Alcohol Abuse

Taiwan
Menzies School of Health Research
National Health and Medical Research Council, Australia; Northern Territory... and other collaborators

Unknown

AIMHI NT Relapse Prevention Trial

Depression | Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Psychoses, Substance Induced

Australia
U.S. Wound Registry
Undersea and Hyperbaric Medical Society (UHMS)

Unknown

Hyperbaric Oxygen Therapy Registry (HBOTR)

Carbon Monoxide Poisoning | Decompression Sickness | Severe Anemia | Idiopathic Sudden Sensorineural Hearing Loss | Necrotizing Soft Tissue Infections | Air or Gas Embolism | Clostridial Myositis and Myonecrosis (Gas Gangrene) | Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias | Peripheral... and other conditions
Rhode Island Hospital

Recruiting

Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis

Carpometacarpal Sprain | Thumb Sprain | Clostridium; Botulinum

United States
Fundacion SEIMC-GESIDA
Janssen-Cilag, S.A.

Completed

A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c) (DETOX)

HIV Infections

Spain
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients

Acute Lymphoblastic Leukaemia | Vincristine Induced Neurotoxicity

Bangladesh
Seoul National University Hospital
Ministry of Health & Welfare, Korea

Completed

A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status

Tuberculosis | Drug-Induced Liver Injury | Adverse Drug Event

Korea, Republic of
Sanofi

Completed

XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy

Colorectal Neoplasms | Colorectal Carcinoma | Metastases
Vastra Gotaland Region

Completed

Neurofilament Light Protein in Peripheral Blood Used as a Biomarker for Neurotoxicity After Isolated Limb Perfusion. (ILP-NfL)

Malignant Melanoma

Sweden
University of York
Medical Research Council; Department for International Development, United...

Completed

A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand Flies (LEISHChallenge)

Leishmaniasis | Cutaneous Leishmaniases | Insect Bites

United Kingdom
Unity Health Toronto

Terminated

Phenobarbital for Severe Acute Alcohol Withdrawal Syndrome (PHENOMANAL)

Alcohol Withdrawal | Alcohol Withdrawal Delirium | Alcohol Withdrawal Seizures

Canada
OSF Healthcare System

Unknown

Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit (PARTI)

Alcohol Withdrawal | Alcohol Withdrawal Delirium

United States
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Columbia University

Withdrawn

Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

Liver Failure | Liver Failure, Acute | Fever | Prevention & Control | Drug Induced Liver Injury

United States
Rajavithi Hospital
Rajavithi Biomolecular Research Center

Completed

Treatment of Survivors After Botulism Outbreak

Respiratory Failure | Botulism

Thailand
Peking University Cancer Hospital & Institute

Completed

Study the Role of Stem Cell in Curing Drug Induced Liver Injury in Metastatic Breast Cancer (MBC) (MBC)

Breast Neoplasms | Neoplasm Metastasis

China
University College, London
Cancer Research UK

Completed

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Lymphoma | Mucositis | Neurotoxicity | Chemotherapeutic Agent Toxicity

United Kingdom
PATH

Completed

Preliminary Evaluation of a Point-Of-Care Liver Function Test (DFA)

HIV | Tuberculosis | Drug-Induced Liver Injury

Vietnam
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia

Inappropriate ADH Syndrome | Water Intoxication | Hyponatremias | Water-Electrolyte Imbalances

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer

Breast Cancer | Fatigue | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults | Chemotherapeutic Agent Toxicity

United States
Mahidol University

Recruiting

Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial

Hepatitis | Tuberculosis | Drug Induced Liver Injury

Thailand
Yuhong Li

Completed

Effect of GM1 in Prevention of Oxaliplatin Induced Neurotoxicity in Stage II/III Colorectal Cancer

Colorectal Cancer | Chemotherapy-induced Neutropenia

China
Jubilee Mission Medical College and Research Institute
INCRE fellowship from DBT, govt of India

Completed

Hyperbaric Oxygenation in Treatment of Alcohol Dependence Syndrome

Alcohol Withdrawal Symptoms | Delirium Tremens (DTs)
Charite University, Berlin, Germany

Completed

Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) (LOKALE)

Infection Resistant to Multiple Drugs

Germany
Mental Health Services in the Capital Region, Denmark

Recruiting

The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis (OPUS-YOUNG)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Depression Severe | Schizotypal Disorder | Acute and Transient Psychotic Disorder, Unspecified | Non-Organic Psychosis | Substance Induced Psychoses

Denmark
Assiut University

Completed

Immune Responses in Hepatocellular Carcinoma Patients After Treatment With Direct Acting Antiviral Drugs

Drug-Induced Liver Injury

Egypt
Northwestern University
Pharmacyclics LLC.

Withdrawn

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Lymphoma | Brain and Central Nervous System Tumors | Neurotoxicity
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases

Solid Tumor | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects

United States
Addex Pharma S.A.

Recruiting

Open-label Safety Study of Dipraglurant (ADX48621) in Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Parkinson Disease | Dyskinesias | Dyskinesia, Drug-Induced

United States
Addex Pharma S.A.

Recruiting

Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Parkinson Disease | Dyskinesias | Dyskinesia, Drug-Induced

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Fatigue | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States

Clinical Trials on Polybrominated Biphenyl Poisoning

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