Clinical Trials on Polycystic Kidney Diseases

Total 383284 results

Mayo Clinic
University of Kansas Medical Center

Completed

Assessment of Longitudinal Changes in Endothelial Function and Oxidative Stress in Normotensive Patients With ADPKD

Autosomal Dominant Polycystic Kidney Disease

United States
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease (ESSENTIAL)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Korea, Republic of
Otsuka Pharmaceutical Development & Commercialization...

Completed

Short-term Renal Hemodynamic Effects of Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

Netherlands
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001]

Autosomal Dominant Polycystic Kidney Disease

Japan
Kyorin University
Otsuka Pharmaceutical Co., Ltd.

Completed

Clinical Implications of DNA Analysis on ADPKD (DNAAA)

Autosomal Dominant Polycystic Kidney Disease

Japan
University of Kansas

Completed

A New Diet for Patients With Autosomal Dominant Polycystic Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
University of Kansas

Completed

Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

ADPKD

United States
Rigshospitalet, Denmark
Aarhus University Hospital

Completed

Effect of Water Intake and Water Restriction on Total Kidney Volume in Autosomal Dominant Polycystic Kidney Disease

ADPKD

Denmark
NYU Langone Health

Completed

High Water Intake to Slow Progression of Polycystic Kidney Disease

Kidney, Polycystic, Autosomal Dominant

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD (HCY)

Autosomal Dominant Polycystic Kidney Disease

United States
University of Chicago

Withdrawn

The Safety and Efficacy of Catheter-based Renal Denervation Using the Vessix™ Renal Denervation System in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patients With Severe Debilitating Pain

Autosomal Dominant Polycystic Kidney Disease
Mayo Clinic

Completed

New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease (MRI Pilot)

Kidney Disease | Autosomal Dominant Polycystic Kidney Disease

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease (OVERTURE)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States, Argentina, Australia, Belgium, Brazil, Canada, Czech Republic, France, Germany, Italy, Japan, Netherlands, Norway, Poland, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Mario Negri Institute for Pharmacological Research

Terminated

Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency (SIRENA-II)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Italy
Thomas Mueller

Unknown

Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function

Kidney Neoplasms | Adult Polycystic Kidney Disease | Kidney Dysfunction

Switzerland
Odense University Hospital

Unknown

Renal Sympathetic Denervation for Reduction of Pain and Improvement of Insulin Sensitivity in Adult Polycystic Kidney Disease

Adult Polycystic Kidney Disease

Denmark
Otsuka Canada Pharmaceutical Inc.

Recruiting

Canadian Medical Assessment of JINARC™ Outcomes Registry (C-MAJOR)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Canada
University Hospital, Brest

Completed

Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD (GeneQuest)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

France
Medical University of Vienna

Unknown

Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease (RAP)

Polycystic Kidney, Type 1 Autosomal Dominant Disease | Polycystic Kidney, Type 2 Autosomal Dominant Disease

Austria
Mario Negri Institute for Pharmacological Research

Completed

Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency (ALADIN2)

Autosomal Dominant Polycystic Kidney Disease

Italy
The Rogosin Institute
Weill Medical College of Cornell University; New York Presbyterian Hospital

Withdrawn

Repository Study of Autosomal Dominant Polycystic Kidney Disease (Repository)

Autosomal Dominant Polycystic Kidney Disease

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease

Chronic Kidney Disease | Autosomal Dominant Polycystic Kidney Disease

Australia, Belgium, Italy, Spain, Sweden, United States, Canada, Netherlands, Czechia, Poland, Germany, Russian Federation, Hungary, Israel, Puerto Rico, Argentina, Denmark, South Africa, United Kingdom, Norway, France, Romania
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Autosomal Recessive Polycystic Kidney Disease (ARPKD)

United States, Belgium, Spain, Germany, United Kingdom, Poland
Mayo Clinic
Polycystic Kidney Disease Foundation

Completed

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study

Kidney, Polycystic, Autosomal Dominant

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Germany, Italy, Belgium, United Kingdom
Assistance Publique - Hôpitaux de Paris
Novartis

Completed

The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients (EVERKYSTE)

Autosomal Dominant Polycystic Kidney Disease

France
University Medical Center Groningen
Radboud University Medical Center

Recruiting

A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease (AGAINST-PLD)

Autosomal Dominant Polycystic Kidney | Polycystic Liver Disease

Netherlands
Kyorin University
Ministry of Health, Labour and Welfare, Japan

Unknown

CCB Safety Study in Treatment of Hypertension of ADPKD

Kidney, Polycystic, Autosomal Dominant

Japan
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease (ACTION)

Autosomal Dominant Polycystic Kidney | ADPKD

United States, Spain, Hungary, United Kingdom, Australia, Bulgaria, Poland, Turkey
Lisbet Brandi

Unknown

Subacute Effect of Tolvaptan on Total Kidney Volume in Adult Patients With Autosomal Dominant Polycystic Kidney Disease (PoCKET)

Autosomal Dominant Polycystic Kidney

Denmark
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycystic Kidney Disease

Germany, Austria, France
Lisa Guay Woodford

Recruiting

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study (ADPKD)

ADPKD

United States
Ministry of Health, Labour and Welfare, Japan

Unknown

Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD)

Kidney, Polycystic, Autosomal Dominant

Japan
TC Erciyes University

Terminated

The Relation Between Uric Acid Level and Endothelial Dysfunction in Patients With Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Turkey
Cantonal Hospital Graubuenden
University of Zurich

Not yet recruiting

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease (SIDIA)

Autosomal Dominant Polycystic Kidney Disease

Switzerland
Rege Nephro Co., Ltd.

Recruiting

Study of Tamibarotene in Patients With ADPKD

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Japan
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
Weill Medical College of Cornell University
The Rogosin Institute

Enrolling by invitation

Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

United States
National Institute of Diabetes and Digestive and...
Washington University School of Medicine; Merck Sharp & Dohme LLC; University... and other collaborators

Completed

HALT Progression of Polycystic Kidney Disease Study B (HALT PKD B)

Kidney, Polycystic

United States
University Hospital, Rouen

Not yet recruiting

Safety of RotigotiNe in Patients With Autosomal Dominant Polycystic Kidney Disease (ETERNAL-PKD)

Kidney Diseases
Mei changlin

Unknown

Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control (RAFALE)

Hypertension | Autosomal Dominant Polycystic Kidney Disease

China
Regulus Therapeutics Inc.

Recruiting

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant | Autosomal Dominant Polycystic Kidney Disease | ADPKD

United States
University of Southern California

Enrolling by invitation

Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD-SAT)

Autosomal Dominant Polycystic Kidney Disease

United States
National Institute of Diabetes and Digestive and...
Washington University School of Medicine; Merck Sharp & Dohme LLC; University... and other collaborators

Completed

HALT Progression of Polycystic Kidney Disease Study A (HALT PKD A)

Kidney, Polycystic

United States
Genzyme, a Sanofi Company

Terminated

A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients (STAGED-PKD)

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Czechia, United States, Italy, Poland, Argentina, Australia, Austria, Canada, China, Denmark, France, Israel, Japan, Korea, Republic of, Netherlands, Portugal, Romania, Spain, Taiwan, Turkey, United Kingdom
Universitair Ziekenhuis Brussel

Not yet recruiting

Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester? (ADKETONE)

ADPKD
University Hospital, Brest

Not yet recruiting

Study and Management of Cystic Complications in Autosomal Dominant Polycystic Kidney Disease (COMPLIK)

Polycystic Kidney Diseases
Changlin Mei
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Completed

Using Preimplantation Genetic Diagnosis in Autosomal Dominant Polycystic Kidney Disease Patients: a Multicenter Clinical Trial (ESPERANCE)

Polycystic Kidney, Type 1 Autosomal Dominant Disease

China

Clinical Trials on Polycystic Kidney Diseases

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