Clinical Trials on Pre-operative

Total 4003 results

Massachusetts General Hospital
Puma Biotechnology, Inc.; Celcuity, Inc.

Withdrawn

Fulvestrant + Neratinib In Breast Cancer (HER2-Signal)

Metastatic Breast Cancer | Invasive Breast Cancer | HER2-negative Breast Cancer | ER Positive Breast Cancer | PR-Positive Breast Cancer | Stage IV (Metastatic) Breast Cancer

United States
Vanderbilt University Medical Center

Recruiting

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Parkinson Disease | Multiple System Atrophy | Orthostatic Hypotension | Pure Autonomic Failure | Autonomic Failure

United States
Harbin Medical University

Active, not recruiting

The Effect of a Psychosomatic Symptom Intervention Program on the Primary Treatment of Differentiated Thyroid Cancer

Pathologically Confirmed Differentiated Thyroid Carcinoma | All Patients Are in the Initial Treatment Phase | Normal Cognitive and Communicative Abilities, Capable of Reading and Understanding Questionnaires in Chinese | Ability to Use a Smartphone | Voluntary Participation in the Study...

China
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
Vanderbilt University Medical Center

Recruiting

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Hypertension | Multiple System Atrophy | Pure Autonomic Failure | Autonomic Failure

United States
Vanderbilt University

Completed

Local Heat Stress in Autonomic Failure Patients With Supine Hypertension

Hypertension | Multiple System Atrophy | Pure Autonomic Failure | Autonomic Failure

United States
Vanderbilt University Medical Center

Terminated

Blood Pressure Lowering Effects of Angiotensin-(1-7) in Primary Autonomic Failure

Shy-Drager Syndrome | Pure Autonomic Failure | Orthostatic Hypotension, Dysautonomic | Autonomic Nervous System Disorders

United States
Mahidol University

Completed

Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients

Septic Shock | Severe Sepsis | Re-intubation | Post Extubation Respiratory Failure

Thailand
Oulu University Hospital
University of Oulu; Academy of Finland; Roche Diagnostics; PerkinElmer, Inc.; Sigrid... and other collaborators

Recruiting

PEPPI Study: Identification of Women at Risk for Placental Dysfunction

Cardiovascular Diseases | Polycystic Ovary Syndrome | Iron-deficiency | Pre-Eclampsia | Intrauterine Growth Restriction | Hypertensive Disorder of Pregnancy | Proteinuria in Pregnancy

Finland
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Pilot Study (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United Kingdom, United States, Germany
The University of Hong Kong

Completed

To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy

Sexually Transmitted Infections | Induced Abortion | Postaboral Pelvic Inflammatory Disease

China
Johannes Gutenberg University Mainz
Bayer; Maastricht University; University of Bonn; Siemens Corporation, Corporate... and other collaborators

Recruiting

VTEval Project - Prospective Cohort Studies to Evaluate and Improve Diagnostics, Management Strategies and Risk Stratification in VTE (VTEval)

Venous Thromboembolism (VTE) | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE)

Germany
Lifespan

Completed

Evaluating the Effectiveness of Incentive Spirometry

Pneumonia | Dyspnea | Atelectasis | Respiratory Rate | Oxygen Saturation | Oxygen Requirements | FEV1 | FVC | Re-intubation | Hospital Length of Stay | Nursing Workload | Incentive Spirometry

United States
Daiichi Sankyo, Inc.

Completed

Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).

Venous Thrombosis | Thromboembolism | Venous Thromboembolism | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE)

France, United States, Japan, Denmark, Italy, Russian Federation, Czechia, Germany, India, Israel, Philippines, Taiwan, Ukraine, Australia, Austria, China, Argentina, Belarus, Belgium, Brazil, Canada, Chile, Estonia, Hungary, Korea, Republic... and more
Medical Compression Systems

Completed

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH) (SAFE)

Bleeding | Pulmonary Embolism (PE) | Deep Vein Thrombosis of Lower Limb

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CPAP for the Treatment of Supine Hypertension

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Pure Autonomic Failure | Supine Hypertension | Autonomic Failure

United States
Vanderbilt University Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Pure Autonomic Failure | Autonomic Failure

United States
Jason Robert Gotlib
Celgene Corporation

Terminated

Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia

Leukemia | Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
Vanderbilt University Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension (6103)

Parkinson's Disease | Multiple System Atrophy | Orthostatic Hypotension | Pure Autonomic Failure

United States
Niguarda Hospital

Completed

Tryptase and Coronary Heart Disease

Acute Coronary Syndrome With ST Elevation on Electrocardiogram | Acute Coronary Syndrome Without ST Elevation on Electrocardiogram | Noncritical Coronary Artery Disease Coronary Stenosis Less Than 50 Per Cent | Aortic Aneurysms

Italy
Istituto Clinico Humanitas
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; Fondazione Salvatore...

Completed

Anti-Cholinergic Receptors Antibodies, Autonomic Profile and Dysautonomia Symptoms in PAF, ALS and POTS (DISAUT-AB) (DISAUT-AB)

Amyotrophic Lateral Sclerosis | Postural Orthostatic Tachycardia Syndrome | Pure Autonomic Failure | Anti-Cholinergic Receptors Antibodies

Italy
Vanderbilt University Medical Center

Recruiting

Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

Multiple System Atrophy | Pure Autonomic Failure | Autonomic Failure | Orthostatic; Hypotension, Neurogenic | Orthostatic; Hypotension, Parkinsonism

United States
University Hospital, Strasbourg, France

Completed

Observational Study of Glucose Tolerance Abnormalities in Patient With Cystic Fibrosis Homozygous for Phe 508 Del CFTR Treated by Lumacaftor-Ivacaftor (GLUCORRECTOR)

Cystic Fibrosis Homozygous for Phe 508 Del CFTR | Glucose Intolerance or Newly Diagnosis Diabetes

France
TScan Therapeutics, Inc.

Completed

Blood Collection Study From COVID-19 Convalescents Previously Hospitalized to Identify Immunogenic Viral Epitopes

Identify the Viral Epitopes of Memory CD8 T Cells From Individuals That Have Recovered From SARS-CoV-2 Infection | Determine Which SARS-CoV-2 Proteins Are Frequently Recognized by T Cells in Patients With Varying HLA Types

United States
Mirvie

Active, not recruiting

MIRACLE of LIFE Study (MoL)

Preterm Birth | Preterm Labor | Preeclampsia | Intrauterine Growth Restriction | Gestational Diabetes Mellitus in Pregnancy | Small for Gestational Age at Delivery | Preterm Birth Complication | HELLP | Preterm Premature Rupture of Membrane | Gestational Hypertension

United States
Erasmus Medical Center

Recruiting

Self-testing for HCV Re-infection in MSM (SELFIE)

HIV-1-infection | Hepatitis C Recurrent

Netherlands
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
AIO-Studien-gGmbH

No longer available

A Randomized, Open-label Phase III Trial of Mapisal® Versus an Urea Hand-foot Cream as Prophylaxis for Capecitabine-induced Hand-foot Syndrome in Patients With Gastrointestinal Tumors or Breast Cancer (PROCAPP)

the Treatment Hand-foot Syndrome Patients With Gastrointestinal Tumors or Breast Cancer, Who Are Treated With Capecitabine

Germany
Daniel Claassen

Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

Parkinson Disease | Multiple System Atrophy | Pure Autonomic Failure | Dementia With Lewy Bodies | Autonomic Failure

United States
Amsterdam UMC, location VUmc
Borstkanker Onderzoek Groep; Comprehensive Cancer Centre The Netherlands; Dutch...

Recruiting

Postoperative Re-irradiaTion With and Without HYPERthermia: Toxicity, Quality of Life and Survival in Patients With Locoregional Recurrent Breast Cancer (RT-HYPE)

Breast Cancer | Hyperthermia | Locoregional Recurrence | Re-irradiation

Netherlands
Ian Law
The Hospital for Sick Children; Mayo Clinic; University of California, Los Angeles and other collaborators

Recruiting

ATrial Tachycardia PAcing Therapy in Congenital Heart (AT-PATCH)

Congenital Heart Disease | Atrial Tachycardia | Atrial Arrhythmia | Pacemaker Re-Entrant Tachycardia

United States, Canada
Alliance Foundation Trials, LLC.
Patient-Centered Outcomes Research Institute

Completed

Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer (CANVAS)

Cancer | Venous Thromboembolism | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Blood Clot

United States
CND Life Sciences

Completed

Synuclein-One Study

Parkinson Disease | Multiple System Atrophy | Pure Autonomic Failure | Dementia With Lewy Bodies

United States
AbbVie

No longer available

Expanded Access to Veliparib

High Grade Serous Ovarian Cancer | Solid Tumors With Documented BRCA, BARD, or PALB or Other Acceptable DNA Mutations or Anomalies That Are Scientifically Sound | Triple Negative Breast Cancer (TNBC) | Patients Requiring Veliparib Suspension Formulation
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
Daiichi Sankyo, Inc.

Completed

Cancer Venous Thromboembolism (VTE)

Cancer | Venous Thromboembolism (VTE) | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE)

United States, Netherlands, Italy, Belgium, France, Hungary
VelosBio Inc.

Completed

A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Solid Tumors (MK-2140-002)

Gastric Cancer | Pancreatic Cancer | NSCLC | Platinum-resistant Ovarian Cancer | Triple-negative Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | Non-squamous Non-small-cell Lung Cancer | Estrogen-receptor-positive Breast Cancer | Progesterone-receptor-positive Breast Cancer | Estrogen-receptor-negative... and other conditions

United States, Canada
Chelsea Therapeutics

Terminated

A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy

Parkinson's Disease | Pure Autonomic Failure | Dopamine Beta Hydroxylase Deficiency | Symptomatic Neurogenic Orthostatic Hypotension | Multiple Systems Atrophy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medical Treatment for Diamond Blackfan Anemia

Hematologic Disease | Fanconi's Anemia

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders

Myelodysplastic Syndromes | Leukemia | Congenital Amegakaryocytic Thrombocytopenia | Severe Congenital Neutropenia | Diamond-blackfan Anemia

United States
Talaris Therapeutics Inc.
Duke University

Withdrawn

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Anemia, Sickle Cell | Thalassemia | Beta-Thalassemia | Bone Marrow Failure Syndromes | Diamond-Blackfan Anemia | Alpha-Thalassemia | Complex and Transfusion-dependent Hemoglobinopathies

United States
University of Oxford
Medical Research Council

Completed

Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy (STAG-MSA)

Multiple System Atrophy | Gait Disorders, Neurologic | Bladder, Neurogenic | Autonomic Failure | Postural Hypotension

United Kingdom
Seoul National University Bundang Hospital

Completed

Analysis of GERD Symptoms Using Gastroesophageal Reflux Impact Score Questionnaire for Quality of Life

Non-erosive Reflux Disease (NERD) | Reflux Esophagitis (RE) | Functional Heartburn (FH)

Korea, Republic of
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
RWTH Aachen University

Completed

Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies (POTSKog)

Cognitive Impairment | Postural Tachycardia Syndrome | Dysautonomia | Pure Autonomic Failure | Ehlers-Danlos Syndrome | Autonomic Failure

Germany
Masonic Cancer Center, University of Minnesota
National Marrow Donor Program

Completed

Stem Cell Transplant for Hemoglobinopathy

Sickle Cell Disease | Thalassemia | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome

United States
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant for Bone Marrow Failure Syndromes

Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Kostmann's Neutropenia

United States
Novartis

Completed

Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload

Myelodysplastic Syndromes | Hemoglobinopathies | Diamond-Blackfan Anemia | Transfusional Iron Overload | Other Inherited or Acquired Anaemia | MPD Syndrome | Other Rare Anaemias

Australia
National Taiwan University Hospital

Unknown

Evaluating the Diagnostic Validity of Inflammation-associated Markers for Tuberculous Pleurisy

To Investigate Diagnostic Aid of the Inflammation and Apoptosis-associated Markers and Apoptosis Pattern of PE Neutrophil for Tuberculous Pleurisy

Taiwan

Clinical Trials on Pre-operative

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Medical Conditions

Drug Interventions

CROs by country

CROs in Cyprus

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Rare Diseases

Drug Interventions

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