Clinical Trials on Predominantly Antibody Deficiencies in Belgium

Total 102 results

Universitaire Ziekenhuizen KU Leuven
KU Leuven

Unknown

Polysaccharide Antibody Response Study (PARS)

Specific Polysaccharide Antibody Deficiency

Belgium
CSL Behring

Terminated

Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

Antibody-mediated Rejection

United States, Spain, France, Netherlands, United Kingdom, Belgium, Germany
IDEWE Occupational Health Services
GlaxoSmithKline

Unknown

Twinrix Alternative Schedule Study

Antibody Response After Vaccination

Belgium
Universitair Ziekenhuis Brussel

Recruiting

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Amyloidosis | Polyneuropathy

Belgium
AZ Sint-Jan AV

Active, not recruiting

Cardiac Amyloidosis in Spinal Stenosis: the CASS-study (CASS)

Cardiac Amyloidosis

Belgium
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD) (cosMOG)

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)

United States, Australia, Belgium, Czechia, France, Germany, Italy, Japan, Korea, Republic of, Mexico, Spain, Sweden, Switzerland, Turkey, Portugal, United Kingdom, Brazil, Ukraine, Taiwan
CSL Behring
ICON Clinical Research

Terminated

Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)

Antibody-mediated Rejection

Korea, Republic of, United States, New Zealand, Spain, Taiwan, Netherlands, Australia, France, Canada, Belgium, Czechia, Hungary, Sweden, Austria, Germany
Centre Hospitalier Universitaire de Liege
Centre Hospitalier Régional de la Citadelle; SYSNAV

Recruiting

Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part.

Amyotrophic Lateral Sclerosis

Belgium
Astellas Pharma Europe B.V.
Veeda Clinical Research

Completed

Treatment of Symptoms in Male Patients With Lower Urinary Tract Symptoms (LUTS) Predominant Storage Symptoms (Overactive Bladder Syndrome) (VENICE)

Lower Urinary Tract Predominant Storage Symptoms

Belgium
Newron Sweden AB
Medtronic; ICON Clinical Research

Terminated

An Open Label, Safety and Tolerability Continuation Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Belgium
Newron Sweden AB
Medtronic; ICON Clinical Research

Completed

A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Belgium
Laurent Servais
Centre Hospitalier Régional de la Citadelle; SYSNAV

Recruiting

Holter of Movement in Patients With Amyotrophic Lateral Sclerosis. (ActiALS)

Amyotrophic Lateral Sclerosis

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Monitoring of Non-invasive Ventilation During Sleep in ALS

Amyotrophic Lateral Sclerosis

Belgium
Brugmann University Hospital

Completed

In-situ Cytokines Expression in the CNS in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium
Newron Sweden AB

Terminated

A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
Newron Sweden AB

Terminated

A Safety Study of sNN0029 Administration Via Intracerebroventricular Route to Patients With ALS

Amyotrophic Lateral Sclerosis

Belgium, Netherlands
University Hospital, Antwerp

Not yet recruiting

Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy

Heart Failure | Amyloidosis | Amyloidosis Cardiac | Cardiomyopathies, Secondary | Amyloid Polyneuropathy | Cardiomyopathy Non-Dilated

Belgium
Queen Fabiola Children's University Hospital

Recruiting

Iron Deficiency in Pediatric Heart Surgery

Iron Deficiency Anemia | Congenital Heart Disease in Children | Cardiac Surgical Procedures | Iron Deficiencies

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Optical Coherence Tomography in Cerebral Amyloidosis

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Dementia Alzheimers | Dementia, Lewy Body

Belgium
Cosmo Technologies Ltd

Completed

Rifamycin SV-MMX® 600 mg Tablets Administered Three or Two Times Daily to Patients With IBS-D

Diarrhea-predominant Irritable Bowel Syndrome

Belgium, Germany, Italy, Spain
Thomas Jefferson University
Jawaharlal Nehru Medical College; Children's Investment Fund Foundation; S. Nijalingappa... and other collaborators

Completed

Reducing Anemia in Pregnancy in India: the RAPIDIRON Trial (RAPIDIRON)

Iron Deficiency Anemia | Infant, Low Birth Weight | Anemia of Pregnancy

India
C.T. Development America, Inc.

Completed

Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis

Amyloidosis

Spain, United States, Italy, Belgium, Netherlands, India, Tunisia, Latvia, Turkey, France, Germany, Estonia, Lithuania, Poland, Russian Federation, Georgia, United Kingdom, Israel, Egypt, Finland, Peru, Sweden, Ukraine
Thomas Jefferson University
Jawaharlal Nehru Medical College; S. Nijalingappa Medical College; Raichur Institute...

Active, not recruiting

RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study (RAPIDIRON-KIDS)

Autism Spectrum Disorder | Iron Deficiency Anemia | Neurodevelopmental Abnormality

India
Rigel Pharmaceuticals

Enrolling by invitation

A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Warm Antibody Autoimmune Hemolytic Anemia

Spain, United States, Australia, Norway, Belarus, Germany, Netherlands, Belgium, Austria, Bulgaria, Czechia, France, Georgia, Italy, Russian Federation, Serbia, Ukraine, United Kingdom
Teva Pharmaceutical Industries, Ltd.

Completed

Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Israel, Italy, United Kingdom
NICHD Global Network for Women's and Children's...
Boston University; University of Colorado, Denver; University of Alabama at Birmingham and other collaborators

Recruiting

Prevention of Iron Deficiency Anemia Post-delivery (PRIORITY)

Postpartum Anemia

Zambia, Congo, The Democratic Republic of the, India, Bangladesh, Pakistan, Guatemala, Kenya
QurAlis Corporation

Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis

Canada, Germany, Netherlands, Ireland, United Kingdom, Belgium
Stichting TRICALS Foundation
Research Foundation Flanders; Stichting ALS Nederland; Fight MND; MNDA; Thierry Latran... and other collaborators

Recruiting

Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, Netherlands, United Kingdom, Sweden, Spain, Australia
Thomas Jefferson University
Jawaharlal Nehru Medical College

Active, not recruiting

Neuroimaging Ancillary Study

Iron Deficiency Anemia | Child Development | Iron Deficiency Anemia of Pregnancy | Iron Deficiency Anemia Treatment | Neurodevelopmental Disorder of Foetus | Fetal Neurodevelopmental Disorder

India
Hoffmann-La Roche

Completed

Safety Extension Study of TRO19622 in ALS

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
Hoffmann-La Roche
European Commission

Completed

Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS (MITOTARGET)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
Janssen Research & Development, LLC

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Amyloidosis

United States, Netherlands, Belgium, Korea, Republic of, France, Sweden, Israel, Turkey, United Kingdom, Brazil, Canada, Mexico, Australia, Germany, Japan, Spain, Denmark, Italy, China, Greece, Poland, Hungary
Novartis Pharmaceuticals

Completed

Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States, Belgium, Canada, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Recruiting

Open Label Extension of TUDCA-ALS Study (TUDCA-ALS OLE)

Amyotrophic Lateral Sclerosis

Germany, France, Netherlands, Italy, United Kingdom, Belgium, Ireland
AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
Rigel Pharmaceuticals

Completed

A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA

Warm Antibody Autoimmune Hemolytic Anemia

United States, Spain, Canada, Australia, Norway, France, Belarus, Germany, Netherlands, Belgium, United Kingdom, Austria, Czechia, Georgia, Italy, Russian Federation, Serbia, Ukraine, Romania, Denmark, Hungary, Bulgaria
Prothena Biosciences Ltd.

Terminated

The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis (VITAL)

Primary Systemic (AL) Amyloidosis

United States, Spain, Israel, Canada, Poland, Netherlands, France, Germany, United Kingdom, Belgium, Denmark, Greece, Australia, Austria, Italy
Alnylam Pharmaceuticals

Completed

DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis

Familial Amyloidotic Cardiomyopathy (FAC)

United States, France, Spain, United Kingdom, Belgium, Brazil
Prothena Biosciences Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis (AFFIRM-AL)

Light Chain (AL) Amyloidosis

United States, Korea, Republic of, Australia, Denmark, France, Italy, Spain, Israel, Taiwan, Austria, Canada, Czechia, Germany, Greece, Hungary, Japan, Netherlands, Poland, Portugal, Turkey, United Kingdom, Belgium, Ireland
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Active, not recruiting

Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS (TUDCA-ALS)

Amyotrophic Lateral Sclerosis (ALS)

United Kingdom, Germany, France, Netherlands, Belgium, Ireland, Italy
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) (PROCLAIM)

Frontotemporal Dementia

United States, Australia, Belgium, Spain, United Kingdom, France
Ionis Pharmaceuticals, Inc.
AstraZeneca

Recruiting

An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

United States, Austria, Belgium, Canada, France, Germany, Israel, Italy, Portugal, Spain, Sweden, United Kingdom, Australia, Greece
ChemoCentryx

Completed

A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis (ADVOCATE)

ANCA-Associated Vasculitis

United States, Australia, Belgium, Canada, France, Italy, Japan, Netherlands, Spain, United Kingdom, Austria, Czechia, Denmark, Germany, Hungary, Ireland, New Zealand, Norway, Sweden, Switzerland
Eidos Therapeutics, a BridgeBio company

Active, not recruiting

Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants

Amyloid Cardiomyopathy, Transthyretin-Related

United States, Spain, Australia, Canada, Italy, Netherlands, Ireland, New Zealand, Belgium, Israel, Greece, Korea, Republic of, Czechia, Brazil, Denmark, Portugal, United Kingdom
Human Genome Sciences Inc., a GSK Company
GlaxoSmithKline

Completed

Belimumab in Remission of VASculitis (BREVAS)

Vasculitis

United States, Australia, France, Spain, Italy, Peru, Belgium, Canada, Germany, Romania, Mexico, United Kingdom, Hungary, Ireland, Poland, Switzerland, Czechia, Russian Federation, Norway, Sweden
ZevraDenmark

Terminated

Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension Trial

Amyotrophic Lateral Sclerosis

United States, Canada, Netherlands, Belgium, Poland, United Kingdom, France, Germany, Italy, Spain, Sweden
Ono Pharmaceutical Co. Ltd

Completed

A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS)

Belgium, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
Ferrer Internacional S.A.
Julius Clinical; Stichting TRICALS Foundation

Active, not recruiting

Study to Investigate the Efficacy and Safety of FAB122 (Daily Oral Edaravone) in Patients With Amyotrophic Lateral Sclerosis (ADORE)

Amyotrophic Lateral Sclerosis

Belgium, Netherlands, United Kingdom, Spain, Germany, France, Ireland, Italy, Poland, Portugal, Sweden
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, China, Korea, Republic of, Belgium, France, Germany, Italy, Japan, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Talampanel for Amyotrophic Lateral Sclerosis (ALS) (ALS)

ALS

United States, Netherlands, Canada, Italy, Spain, Belgium, France, Germany, Hungary, Israel

Clinical Trials on Predominantly Antibody Deficiencies in Belgium

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