Clinical Trials on Primary Immune Deficiency in Adults in Singapore

Total 64 results

National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma

United States, Singapore
KK Women's and Children's Hospital
Singapore General Hospital

Recruiting

CD19-Directed Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory B-Lineage Leukaemia / Lymphoma - A Feasibility Protocol

Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | B-cell Acute Lymphoblastic Leukemia | Large B-cell Lymphoma

Singapore
KK Women's and Children's Hospital
National University Hospital, Singapore; Singapore General Hospital

Recruiting

Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR

Singapore
Danone Asia Pacific Holdings Pte, Ltd.
Nutricia Research

Terminated

Meal Tolerance Trial in Pregnant Women Diagnosed With Gestational Diabetes Mellitus. (GDM-MTT)

Gestational Diabetes Mellitus in Pregnancy

Singapore
Singapore Institute for Clinical Sciences
National University Polyclinics, Singapore; National University of Singapore

Completed

A Mobile Health-enabled Lifestyle Intervention Among Women With History of Gestational Diabetes(GDM) (Reverse-DM)

Healthy | Diabetes, Gestational | Gestational Diabetes Mellitus in Pregnancy

Singapore
Clinical Nutrition Research Centre, Singapore

Unknown

Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Function

Insulin Resistance | Glucose Intolerance | Insulin Sensitivity | Energy Supply; Deficiency

Singapore
ViiV Healthcare
Pfizer

Completed

Effect Of Maraviroc On The Pharmacokinetics Of Digoxin

HIV Infections | Healthy

Singapore
KK Women's and Children's Hospital
Singapore Thong Chai Medical Institution

Unknown

Traditional Chinese Medicine in Management of Childhood Asthma (TraCMAst)

Asthma in Children

Singapore
National University Hospital, Singapore

Recruiting

CARTALL: Chimeric-Antigen Receptor (CAR) T-Cell Therapy for Relapsed/ Refractory T-Lineage Acute Lymphoblastic Leukaemia

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome | Refractory Leukemia

Singapore
National University Hospital, Singapore

Recruiting

ALaCART-B: Acute Leukemia and Chimeric Antigen Receptor-T Cell Therapy for B-lymphoblastic Leukemia. (ALaCART)

Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Lymphoblastic Leukemia, Acute Adult | Lymphoblastic Leukemia in Children | CAR | CAR T-Cell-Related Encephalopathy Syndrome

Singapore
Tan Tock Seng Hospital
National Healthcare Group, Singapore; Singapore Immunology Network

Unknown

Evaluation of Metabolic Predictors of Influenza Vaccine Immune Response in the Singapore Elderly Population - the DYNAMIC Trial

Diabetes Mellitus | Immune Response | Vitamin D Deficiency | Elderly | Influenza Vaccine | Metabolic Disease

Singapore
National University Hospital, Singapore

Completed

The Effectiveness of a Mobile Interactive Supervised Therapy (MIST) Intervention for Improving Adherence to HIV Medication

HIV-infection/Aids

Singapore
Changi General Hospital
National University Hospital, Singapore; Merck Sharp & Dohme LLC

Completed

Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers

Human Immunodeficiency Virus

Singapore
ViiV Healthcare
Pfizer

Completed

Investigation Of Safety And Pharmacokinetics Following A Single Oral Dose Of 300 Mg Maraviroc In Healthy Male Japanese Volunteers

Human Immunodeficiency Virus (HIV) Infection

Singapore
National Cancer Centre, Singapore

Terminated

Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Palmar-plantar Erythrodysesthesia | Dermatologic Complications

Singapore
Singapore General Hospital
National University Hospital, Singapore; National Cancer Center Singapore,... and other collaborators

Withdrawn

Study Of Durvalumab and Lenalidomide In R/R EBV Associated DLBCL Subtypes, Primary CNS And Testicular DLBCL (DuRIANS)

EBV Related Non-Hodgkin's Lymphoma | Primary CNS Lymphoma | Primary Testicular Lymphoma

Singapore
Changi General Hospital
Singapore General Hospital

Recruiting

Outcome of Patients With Primary Aldosteronism (PA_Outcome)

Primary Aldosteronism | Hypokalemia | Chronic Renal Disease | Cardiovascular Morbidity | Mineralocorticoid Excess | Adrenalectomy; Status | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Mineralocorticoid Antagonists [Aldosterone...

Singapore
National University Health System, Singapore
Baxter Healthcare Corporation

Terminated

Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS (U-Protect)

Respiratory Distress Syndrome, Adult

Singapore
National University Health System, Singapore

Completed

PaO2/FiO2*PEEP (P/FP) Ratio and Mortality in Acute Respiratory Distress Syndrome.

Adult Respiratory Distress Syndrome

Singapore
University of Melbourne
The Alfred

Recruiting

Low Dose Nivolumab in Adults Living With HIV on Antiretroviral Therapy (NIVO-LD)

HIV I Infection

Singapore, Australia
National University, Singapore
National Centre for Infectious Diseases, Singapore; Action for AIDS Singapore

Completed

The People Like Us Evaluation Study

HIV/AIDS | Health Behavior | Stigma, Social | Sexually Transmitted Infection | Homosexuality | Health Care Seeking Behavior

Singapore
National University Hospital, Singapore
National University of Singapore

Active, not recruiting

Effect of Low-dose 500 mg Abiraterone Acetate in Treatment of Metastatic Prostate Cancer Patients

Prostate Cancer | Metastatic Cancer | Castration-resistant Prostate Cancer | Hormone Sensitive Prostate Cancer

Singapore
National Cancer Centre, Singapore
Ferring Pharmaceuticals; National Medical Research Council (NMRC), Singapore; Duke-NUS Graduate Medical School and other collaborators

Recruiting

Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients

Nasopharyngeal Cancer | Prostate Cancer | Other Cancer

Singapore
National Cancer Centre, Singapore
Bristol-Myers Squibb; OncoQuest Pharma USA Inc.

Unknown

Clinical Trial of Chemotherapy, Oregovomab and Nivolumab in Patients With Epithelial Cancer of Ovarian, Tubal or Peritoneal Origin (ORION-02)

Epithelial Ovarian Cancer

Singapore
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy

Primary IgA Nephropathy

Canada, Australia, New Zealand, Singapore
Kirby Institute
Merck Sharp & Dohme LLC; amfAR, The Foundation for AIDS Research; Abbott

Completed

A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen (SECOND-LINE)

HIV Infections

Taiwan, Australia, Argentina, Singapore, India, France, South Africa, Chile, Germany, Hong Kong, Ireland, Malaysia, Mexico, New Zealand, Nigeria, Peru, United Kingdom
Abbott

Completed

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects

HIV Infections

Spain, United Kingdom, United States, France, Australia, Germany, Singapore
National Cancer Institute (NCI)

Active, not recruiting

Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma

Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Recurrent Nasopharyngeal Undifferentiated Carcinoma | Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 | Adult Nasal Type Extranodal NK/T-Cell Lymphoma | Stage IV Nasopharyngeal Undifferentiated Carcinoma...

United States, Singapore, China, Japan
Bristol-Myers Squibb

Completed

Rollover Study for Zerit (Stavudine) ER Studies (-096, -099)

HIV Infections | AIDS

Belgium, Portugal, Spain, United States, Argentina, Canada, France, Italy, Mexico, Puerto Rico, Singapore, South Africa, Thailand, Russian Federation, Israel, Brazil
Bristol-Myers Squibb

Completed

BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada

HIV Infections

Chile, Portugal, Spain, Italy, United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Colombia, Costa Rica, Dominican Republic, France, Germany, Guatemala, Hong Kong, Indonesia, Mexico, Netherlands, Panama, Peru, Puerto... and more
Anthera Pharmaceuticals

Completed

BRIGHT-SC: Blisibimod Response in IgA Nephropathy Following At-Home Treatment by Subcutaneous Administration

IgA Nephropathy

Czechia, Germany, Hong Kong, Korea, Republic of, Malaysia, Philippines, Singapore, Taiwan, Thailand, United Kingdom
Allergan

Completed

A Long-term Follow-up Study of Botulinum Toxin Type A in Patients With Overactive Bladder as a Result of Spinal Injury or Multiple Sclerosis

Overactive Bladder

Poland, United Kingdom, Portugal, South Africa, Ukraine, Australia, Netherlands, Canada, Singapore, Russian Federation, Germany, Brazil, Austria, Slovakia, Czechia, United States, Taiwan, Italy, France, Belgium, Spain, New Zealand
Pyramid Biosciences

Terminated

Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

Solid Tumor, Adult | Desmoplastic Small Round Cell Tumor | Brain Tumor, Primary

France, United States, Spain, Hong Kong, United Kingdom, Australia, Singapore, Germany, Korea, Republic of, Italy, Denmark
Abbott

Completed

Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral Naive Human Immunodeficiency Virus Type 1 Infected Subjects

Human Immunodeficiency Virus Infections

United States, Australia, Belgium, Canada, Czech Republic, France, Germany, Greece, Ireland, Italy, Netherlands, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Switzerland, Taiwan, United Kingdom
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection (VOYAGE-1)

Hepatitis C Virus (HCV)

China, Korea, Republic of, Singapore
Novartis Pharmaceuticals

Recruiting

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP) (VAYHIT1)

Primary Immune Thrombocytopenia (ITP)

China, United States, Spain, Singapore, Austria, Germany, Belgium, Italy, Japan, Czechia, Hong Kong, Hungary, Malaysia, Argentina, Bulgaria, Turkey, Vietnam, Australia, Thailand, Mexico, United Kingdom, France, Romania, Norway, India
EMD Serono
ZymoGenetics

Terminated

The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis

Lupus Nephritis

United States, Singapore, Malaysia, Taiwan, Czech Republic
Alnylam Pharmaceuticals

Terminated

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

IgA Nephropathy (IgAN) | Berger Disease | Glomerulonephritis, IgA

Canada, Malaysia, France, Sweden, United Kingdom, Philippines, Singapore, Spain, Taiwan
Merck KGaA, Darmstadt, Germany

Completed

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Growth Hormone Deficiency | Turner Syndrome

Argentina, Australia, Austria, Canada, France, Germany, Italy, Norway, Russian Federation, Singapore, Spain, Sweden, United Kingdom
Novartis Pharmaceuticals

Recruiting

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Primary IgA Nephropathy

Japan, Korea, Republic of, United States, Denmark, France, Taiwan, Belgium, Israel, Thailand, Germany, India, Czechia, Malaysia, Argentina, Singapore, China, Australia, Norway, Turkey, United Kingdom, Brazil, Hong Kong, Netherlands, C... and more
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL) (CheckMate 647)

Lymphoma

United States, Canada, Hong Kong, Italy, Japan, France, Israel, Germany, Hungary, Brazil, Czechia, Russian Federation, Singapore
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Efficacy and Safety of RO7434656 in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression (IMAGINATION)

Primary IgA Nephropathy

Korea, Republic of, Australia, Spain, United Kingdom, Taiwan, China, Japan, France, United States, Italy, Greece, Czechia, Singapore, Argentina, Germany, Brazil, Poland, Canada
Novartis Pharmaceuticals

Recruiting

A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids (VAYHIT2)

Primary Immune Thrombocytopenia

United States, China, Germany, Spain, Singapore, Japan, Taiwan, Belgium, Italy, Czechia, Hungary, Malaysia, Korea, Republic of, Turkey, Argentina, Thailand, India, United Kingdom, France, Australia, Romania, Austria, Norway, Netherlands, Philippin...
Takeda

Active, not recruiting

A Study of Mezagitamab in Adults With Primary Immunoglobulin A Nephropathy Receiving Stable Background Therapy

Glomerulonephritis | Kidney Disease

Taiwan, Australia, Hungary, Spain, United Kingdom, United States, China, Korea, Republic of, Italy, Japan, Singapore
Turning Point Therapeutics, Inc.

Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Lymphoma | Locally Advanced Solid Tumors | Metastatic Solid Tumors | Primary CNS Tumors

United States, Korea, Republic of, Spain, Singapore, Taiwan, Australia, Italy, Canada, France, Denmark, United Kingdom
GlaxoSmithKline

Recruiting

A Study of Belantamab Mafodotin Monotherapy in Multiple Myeloma Participants With Normal and Varying Degree of Impaired Renal Function (DREAMM12)

Multiple Myeloma

United States, Greece, Korea, Republic of, Singapore
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation

IgA Nephropathy

Colombia, Taiwan, Czechia, India, Turkey, Belgium, Netherlands, Singapore, Australia, Korea, Republic of, Thailand, Argentina, Germany, Israel, Japan, Sweden, United Kingdom, Brazil, China, Hong Kong, Norway, Finland, France, Denmark, M...
Amgen

Terminated

AMG 386 (Trebananib) in Ovarian Cancer (TRINOVA-2)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States, Belgium, Germany, Italy, United Kingdom, Canada, Denmark, Switzerland, Hong Kong, Austria, Slovakia, Taiwan, Hungary, France, Singapore, Australia, Poland, New Zealand
Aurinia Pharmaceuticals Inc.

Completed

AURA-LV: Aurinia Urinary Protein Reduction Active - Lupus With Voclosporin (AURA-LV) (AURA-LV)

Lupus Nephritis

United States, Bangladesh, Belarus, Bulgaria, China, Ecuador, Georgia, Guatemala, Korea, Republic of, Mexico, Philippines, Poland, Russian Federation, Serbia, Singapore, Spain, Sri Lanka, Taiwan, Thailand, Ukraine
Novartis Pharmaceuticals

Recruiting

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

Lupus Nephritis

France, Spain, Israel, Turkey, United States, Germany, India, Hungary, Malaysia, Portugal, Brazil, China, Puerto Rico, Hong Kong, Mexico, Singapore

Clinical Trials on Primary Immune Deficiency in Adults in Singapore

Sponsors and Collaborators

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