Clinical Trials on Primary Immunodeficiency Syndromes in Czechia

Total 1064 results

medac GmbH
Syneos Health; Celerion

Completed

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukaemias (ALL) | Acute Myeloid Leukaemias (AML) | Juvenile Myelomonocytic Leukaemias (JMML)

Germany, United Kingdom, Italy, Austria, Czechia, Poland
Amgen

Completed

Darbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

MDS

Germany, Italy, Belgium, Czechia, Switzerland, France, Austria, Greece, Spain
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Active, not recruiting

A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve (COMMANDS)

Myelodysplastic Syndromes

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Netherlands, Poland, Portugal, Russian Federation, Spain, Sweden, Switzerland, Taiwan, Turke... and more
Allecra
Linical Co., Ltd.

Recruiting

A Study to Investigate PK, Safety, Tolerability of Cefepime-enmetazobactam in Pediatric Participants With cUTI

Complicated Urinary Tract Infection

Spain, France, Czechia, Hungary, Poland, Slovakia
Womed

Active, not recruiting

PREvention of Intrauterine Adhesion After Adhesiolysis With Novel Tri-block deGradable Polymer Film. (PREG2)

Asherman Syndrome | Intrauterine Adhesion

Switzerland, Spain, France, China, Belgium, Czechia, Italy
Astellas Pharma Europe B.V.

Completed

A Randomized Study Comparing Placebo and ASP3652 in the Treatment of Women With Bladder Pain Syndrome / Interstitial Cystitis (BPS/IC) (AMARANTH)

Pain | Urologic Diseases | Cystitis, Interstitial | Urinary Bladder Disease

Belgium, Czechia, Denmark, Germany, Latvia, Lithuania, Netherlands, Poland, Portugal, Romania, Russian Federation, Spain
Ferring Pharmaceuticals

Completed

A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment

Infertility

Belgium, Denmark, Spain, Czechia
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Myelodysplastic Syndromes | Leukemia

Switzerland, Netherlands, France, Belgium, Germany, Sweden, Croatia, Czech Republic, Italy
Ipsen

Completed

Efficacy and Safety Study of Dysport® Used for Migraine Prophylaxis

Migraine

Czechia, Poland, Slovakia
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Mach Gaensslen Foundation; Baxalta Innovations...

Recruiting

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) (TTP registry)

Thrombotic Thrombocytopenic Purpura | Congenital Thrombotic Thrombocytopenic Purpura | Familial Thrombotic Thrombocytopenic Purpura | Thrombotic Thrombocytopenic Purpura, Congenital | Upshaw-Schulman Syndrome

United States, Austria, Czechia, Germany, Japan, Norway, Switzerland
Celgene

Completed

A Study of Lenalidomide Versus Placebo in Subjects With Transfusion Dependent Anemia in Lower Risk Myelodysplastic Syndrome (MDS) Without Del 5q (MDS-005)

Anemia

United States, Belgium, Spain, United Kingdom, Austria, Canada, Germany, Portugal, France, Australia, Israel, Japan, Italy, Czechia, Poland, Turkey
Novartis Pharmaceuticals

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Basal Cell Carcinoma

Greece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
RECORDATI GROUP

Completed

Effects of Rec 0/0438 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Injury

Neurogenic Detrusor Overactivity

Czechia, France, Poland, Portugal
Celgene

Completed

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States, Australia, Canada, Czechia, France, Germany, Italy, Korea, Republic of, Mexico, Poland, Sweden, United Kingdom, Belgium, Brazil, Denmark, Finland, Greece, Israel, Netherlands, Norway, Portugal, Spain, Turkey
Pieris Pharmaceuticals GmbH
FGK Clinical Research GmbH

Completed

Phase 2a Study to Evaluate PRS-080 in Anemic Chronic Kidney Disease Patients

Anemia of Chronic Kidney Disease

Czechia, Germany
SOTIO a.s.

Completed

Phase II Study of DCVAC/PCa After Primary Radiotherapy for Patients With High Risk Localized Prostate Cancer

Prostate Cancer

Czechia
Charles University, Czech Republic

Recruiting

Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS (STARS)

Pelvic Organ Prolapse | Cystocele | Cystocele and Incomplete Uterovaginal Prolapse

Czechia, Slovakia
The Medicines Company
The Cleveland Clinic

Completed

MDCO-216 Infusions Leading to Changes in Atherosclerosis: A Novel Therapy in Development to Improve Cardiovascular Outcomes - Proof of Concept Intravascular Ultrasound (IVUS), Lipids, and Other Surrogate Biomarkers Trial (PILOT)

Acute Coronary Syndrome

Poland, Netherlands, Hungary, Canada, Czechia
Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
SOTIO a.s.

Completed

DCVAC/OvCa After Standard-of-care Chemotherapy in Women With Relapse of Platinum-sensitive Epithelial Ovarian Cancer

Ovarian Cancer Recurrent

Czechia
Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
Astex Pharmaceuticals, Inc.

Completed

Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic

United States, Spain, Korea, Republic of, France, Denmark, Canada, Germany, Italy, Czechia, United Kingdom, Poland, Japan, Sweden, Belgium
Boston Scientific Corporation

Completed

Rezum I Pilot Study for Benign Prostatic Hyperplasia (Rezum Pilot)

Prostatic Hyperplasia | Benign Prostatic Hyperplasia | Prostatic Hyperplasia, Benign | Prostatic Hypertrophy | Prostatic Hypertrophy, Benign | Adenoma, Prostatic | Prostatic Adenoma | Rezum

Dominican Republic, Czechia, Sweden
Aquinox Pharmaceuticals (Canada) Inc.

Unknown

Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome (LEADERSHIP 301)

Interstitial Cystitis | Painful Bladder Syndrome | Bladder Pain Syndrome | Chronic Interstitial Cystitis

United States, Belgium, Canada, Czechia, Denmark, Hungary, Latvia, Netherlands, Poland, Romania, Spain, United Kingdom
Universitaire Ziekenhuizen KU Leuven

Terminated

Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis (SCOTCH;)

Liver Cirrhosis

Spain, United Kingdom, Denmark, Germany, Czechia, Belgium, Italy
Medical University of Vienna

Completed

Lavage of the Uterine Cavity for the Diagnosis of Ovarian and Tubal Carcinoma - Study of Sensitivity and Specificity (LUDOC II)

Ovarian Epithelial Cancer

Austria, Belgium, Czechia, Germany
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
Millennium Pharmaceuticals, Inc.

Completed

An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic

United States, Israel, Spain, France, Ireland, Canada, Germany, Czechia, Italy, Netherlands, Belgium, Bulgaria
Universitaire Ziekenhuizen KU Leuven
UZ Leuven, Leuven, Belgium; Policlinico Universitario A. Gemelli, IRCSS, Rome... and other collaborators

Recruiting

Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.

Cervical Cancer | Ovarian Neoplasms | Ovarian Cancer | Metastatic Cancer | Pelvic Cancer | Endometrial Cancer | Ovarian Carcinoma | Uterus Cancer | Sarcoma Uterus

Belgium, Czechia, Italy, Sweden
Universitätsklinikum Hamburg-Eppendorf
Clinical Trial Center North (CTC North GmbH & Co. KG); DKMS Stiftung Leben...

Recruiting

Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia

Myelodysplastic Syndromes | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission

Germany, Spain, Italy, Austria, Czechia, Finland, Russian Federation
Millendo Therapeutics US, Inc.

Terminated

Nevanimibe HCl for the Treatment of Classic CAH

Congenital Adrenal Hyperplasia

Spain, Israel, France, Brazil, Czechia
European Organisation for Research and Treatment...

Unknown

Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

Belgium, Netherlands, Germany, Italy, United Kingdom, Austria, Czech Republic, Croatia, Turkey, Switzerland
Pfizer

Completed

Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

Spain, Canada, Austria, Czechia, France, Hungary, Italy, Japan, Mexico, Poland, United Kingdom
Novartis Pharmaceuticals

Recruiting

Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NEPTUNUS-1)

Sjogren Syndrome

Brazil, Portugal, United States, Belgium, Spain, Germany, Korea, Republic of, Czechia, Mexico, France, Turkey, China, Guatemala, Austria, Chile, Poland, Singapore, Lithuania
Novartis
The TIMI Study Group

Completed

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Myocardial Ischemia | Post Acute Coronary Syndrome

Germany, Spain, United States, Belgium, Canada, Czech Republic, Hungary, Netherlands, Poland, Russian Federation, Sweden
Bristol-Myers Squibb
Pfizer; Duke Clinical Research Institute

Completed

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Acute Coronary Syndromes

Australia, Germany, Poland, United States, Spain, Brazil, France, Netherlands, Argentina, Mexico, Russian Federation, Colombia, Austria, Belgium, Czechia, Hungary, Israel, Peru, Switzerland, Korea, Republic of, Canada, Romania, Sweden, Ukrai... and more
LMU Klinikum
Seventh Framework Programme; NBIA Alliance

Recruiting

TIRCON International NBIA Registry (TIRCON)

Neurodegeneration With Brain Iron Accumulation (NBIA) | Pantothenate Kinase-associated Neurodegeneration (PKAN) | Aceruloplasminemia | Beta-Propeller Protein-Associated Neurodegeneration (BPAN) | Mitochondrial Membrane Protein Associated Neurodegeneration (MPAN) | Fatty Acid Hydroxylase-associated... and other conditions

Canada, Czechia, Germany, Italy, Netherlands, Poland, Serbia, Spain
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Novartis Pharmaceuticals

Recruiting

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. (NEPTUNUS-Ext)

Sjogrens Syndrome

United States, Spain, Austria, Belgium, Japan, Germany, Turkey, Hungary, Israel, Taiwan, Italy, France, Colombia, Argentina, Portugal, Australia, Slovakia, United Kingdom, Guatemala, Brazil, Czechia, Poland, Bulgaria, Canada, Lithuania, R...
Faron Pharmaceuticals Ltd
Seventh Framework Programme

Terminated

Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS) (INTEREST)

Respiratory Distress Syndrome, Adult

Spain, United Kingdom, France, Italy, Finland, Czechia, Belgium, Germany
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study (APACE)

Myocardial Infarction | Angina, Unstable

Spain, Switzerland, Czechia, Italy, Poland
Novartis
Ministry of Health, Czech Republic

Completed

Fluvastatin in the Therapy of Acute Coronary Syndrome

Myocardial Infarction | Coronary Disease

Czech Republic
Instituto Grifols, S.A.

Terminated

Study of the Efficacy and Safety of Immune Globulin Intravenous (Human) Flebogamma® 5% DIF in Patients With Post-polio Syndrome (FORCE)

Post-polio Syndrome

United States, Denmark, Spain, Germany, Poland, Canada, Czechia, Italy, Netherlands
B. Braun Melsungen AG

Completed

Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)

Catheter Related Bloodstream Infection | Bacteriaemia

Czech Republic
Rhizen Pharmaceuticals SA

Completed

Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors

Solid Tumor | Metastatic Breast Cancer | Locally Advanced Breast Cancer | Extensive-stage Small-cell Lung Cancer | Platinum-Sensitive Fallopian Tube Carcinoma | Platinum-sensitive Ovarian Cancer | Platinum-Sensitive Peritoneal Cancer

Czechia, Poland
King's College London
King's College Hospital NHS Trust; Charles University, Czech Republic; Hopital... and other collaborators

Recruiting

Biology of Juvenile Myoclonic Epilepsy (BIOJUME)

Juvenile Myoclonic Epilepsy

United States, Canada, Czechia, Denmark, Estonia, France, Italy, Norway, United Kingdom
Allergan

Completed

Long Term Follow-up Study of Safety and Efficacy of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence

Overactive Bladder | Urinary Incontinence

Poland, United Kingdom, Belgium, Canada, Russian Federation, United States, Germany, Czechia
Allergan

Completed

A Study Evaluating the Efficacy and Safety of BOTOX® or Solifenacin in Patients With Overactive Bladder and Urinary Incontinence

Overactive Bladder | Urinary Incontinence

Poland, United Kingdom, Germany, Canada, Belgium, United States, Czechia

Clinical Trials on Primary Immunodeficiency Syndromes in Czechia

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