Clinical Trials on Primary Brain Tumor

Total 100228 results

National Cancer Institute (NCI)

Completed

Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Masonic Cancer Center, University of Minnesota

Completed

Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor

Glioblastoma | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma

United States
Hellenic Cooperative Oncology Group

Completed

Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors

Breast Tumors | Brain Metastases | Lung Tumors

Greece
Stanford University

Not yet recruiting

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

GDC-0449 in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Pazopanib in Treating Patients With Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

CCI-779 in Treating Patients With Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Yusuf Menda
National Cancer Institute (NCI); Holden Comprehensive Cancer Center; Perspective...

Enrolling by invitation

A First-in-human Clinical Trial to Evaluate an Alpha-radiation Imaging Agent

Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases

Brain Tumor | Metastatic Melanoma | Brain Metastases | Glioma of Brain

United States
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Recurrent Childhood... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
BioTex, Inc.

Completed

MR Guided Laser Interstitial Thermal Therapy for the "Minimal Invasive" Treatment of Brain Metastasis and Primary Brain Tumors

Brain Neoplasms | Brain Cancer | Brain Tumor | Recurrent Brain Tumor

France
Ontario Clinical Oncology Group (OCOG)
Ontario Cancer Research Network

Completed

The Roles of Tissue Factor in Malignant Gliomas

Venous Thromboembolism | Brain Tumors

United States, Canada
AC Camargo Cancer Center
H. Lee Moffitt Cancer Center and Research Institute

Completed

Study of Tamoxifen in Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression (HORMONET)

Neuroendocrine Tumors | Estrogen Receptor Positive Tumor | Progesterone Receptor Positive Tumor

United States, Brazil
David Bushnell
National Cancer Institute (NCI); National Institutes of Health (NIH); Holden...

Active, not recruiting

Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors

Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting | Neuroendocrine Tumor, Malignant

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
James Elder

Completed

Carboplatin in Treating Patients With Recurrent High-Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Recurrent Adult Brain Tumor

United States
Manmeet Ahluwalia, MD
National Cancer Institute (NCI); Novartis

Completed

Dovitinib in Treating Patients With Recurrent or Progressive Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

Neoadjuvant and Adjuvant Fenretinide Compared With Adjuvant Fenretinide Alone in Treating Patients Who Are Undergoing Surgical Resection For Recurrent Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
RenJi Hospital

Recruiting

Exploratory Clinical Study of Autologous Tumor-infiltrating Lymphocyte Injection (GT201) for Advanced Gynecologic Tumors

Solid Tumor

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer (IMPROVE)

Melanoma | Head and Neck Cancer | Gynecologic Cancer | Thoracic Cancer | Head and Neck Tumor | Gynecologic Tumor | Thoracic Tumor

United States
Careggi Hospital

Completed

Microscopic-spectroscopic Examination for Urothelial Tissue Characterization (MSUT)

Bladder Tumor
Hopital Foch

Completed

Endoscopic Resection of Bladder Tumors

Bladder Tumor

France
University of Iowa
Novartis

Not yet recruiting

177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry (LUMOD-ID)

Neuroendocrine Tumors | Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1

United States
Duke University
Novartis; National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

Osteoporosis | Brain Tumors | Central Nervous System(CNS)Malignancies

United States
Sykehuset i Vestfold HF
Oslo University Hospital; Helse Sor-Ost; University of Geneva, Switzerland; Car...

Recruiting

Surgery With Extended (D3) Mesenterectomy for Small Bowel Tumors

Quality of Life | Small Bowel Cancer | Lymph Node Metastases | Small Bowel Carcinoid Tumor | Tumor Metastasis

Norway
H. Lee Moffitt Cancer Center and Research Institute
Olympus Corporation

Completed

Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas

Glioma | Brain Tumor

United States
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
University of Birmingham
University of Leeds; Jazz Pharmaceuticals; The Brain Tumour Charity

Recruiting

ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids (ARISTOCRAT)

Glioblastoma | Brain Tumor | Cannabis | Brain Tumor, Recurrent

United Kingdom
Massachusetts General Hospital
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Active, not recruiting

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

Astrocytoma | Brain Tumor | Ependymoma | Ganglioglioma | Low Grade Glioma

United States
UroSee Corporation

Unknown

Assessment of the Uro-C Cystoscope for Use in Diagnostic Cystoscopy Procedures

Bladder Tumor

United States
Samsung Medical Center

Completed

Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation

Mycoses | Brain Tumor | Neuroblastoma | Retinoblastoma | Wilms Tumor

Korea, Republic of
Hospital del Río Hortega

Recruiting

Brain Tumor Intraoperative Ultrasound Database (BraTioUS-DB)

Glioma | Glioblastoma | Brain Neoplasms | Brain Cancer | Brain Tumor

Italy, Spain, India
University Medical Center Groningen
Genzyme, a Sanofi Company

Completed

Safety and Imaging Study of GC1008 in Glioma

Primary Brain Tumors

Netherlands
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial

Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific
Jean M. Tersak, M.D.
Pfizer

No longer available

Treatment With Crizotinib Single Patient Expanded Access IND 134375

Inflammatory Myofibroblastic Tumour
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

United States
Xiangya Hospital of Central South University

Not yet recruiting

The Effect of Preoperative Walking Exercises on the Prognosis of Supratentorial Brain Tumours Patients After Craniotomy

Postoperative Complications | Exercise | Supratentorial Brain Tumor | Cognition

China
Tel-Aviv Sourasky Medical Center

Unknown

Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors

Glioma

Israel
Northwell Health

Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Glioblastoma | Brain Cancer | Brain Tumor | GBM | Brain Neoplasm | Brain Neoplasm, Malignant | EGFR Gene Overexpression

United States
National Cancer Institute (NCI)

Withdrawn

A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors

Sarcoma | Osteosarcoma | Brain Tumor | Neuroblastoma | Wilms Tumor

United States
Centre Leon Berard
Transgene

Completed

Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors. (ISI-JX)

Advanced Tumor | Metastatic Tumor

France
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Solving Kids' Cancer; Ty Louis Campbell Foundation and other collaborators

Active, not recruiting

Phase I Study of APX005M in Pediatric CNS Tumors

Glioblastoma Multiforme | Medulloblastoma | High-grade Astrocytoma NOS | CNS Primary Tumor, Nos | Ependymoma, NOS | Diffuse Intrinsic Pontine Gliomas (DIPG)

United States
St. Jude Children's Research Hospital

Recruiting

Methionine PET/CT Studies In Patients With Cancer

Hodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Ependymoma | Medulloblastoma | Non Hodgkin Lymphoma | Neuroblastoma | Craniopharyngioma | Rhabdomyosarcoma | Other | Brain Stem Glioma | Brain Tumors and/or Solid Tumors Including | High Grade CNS Tumors | Low Grade CNS Tumors

United States
University of Minnesota

Recruiting

Spectroscopic Magnetic Resonance Imaging of Glioma (MEGA-PRESS)

Brain Tumor-Glioma

United States

Clinical Trials on Primary Brain Tumor

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