Clinical Trials on Primary Neoplasm

Total 147336 results

City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Microbial Diversity Between Inflamed and Non-inflamed Skin of Patients With Immune Checkpoint Inhibitor-Induced Dermatitis

Genito-Urinary Neoplasm

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Accuray Incorporated

Completed

SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine

Stage IV Skin Melanoma | Metastatic Malignant Neoplasm in the Brain | Metastatic Malignant Neoplasm in the Spine

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

First-in-Human Study of TAK-280 in Participants With Unresectable Locally Advanced or Metastatic Cancer

Unresectable Locally Advanced or Metastatic Cancer

Spain, United States, Australia, Canada
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Measurement and Characterization of Circulating Endothelial Cells or Circulating Tumor Cells or Circulating DNA in Adult Patients With Metastatic Cancer (Liquid Biopsy)

Metastatic Cancer

France
Centre Hospitalier Intercommunal Creteil

Recruiting

Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization (PELVIMASS2)

Endometriosis | Pelvic Neoplasms

France
National Cancer Institute (NCI)

Completed

Sorafenib and Bevacizumab to Treat Ovarian, Fallopian and Peritoneal Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | Ovarian Neoplasm

United States
National Cancer Institute (NCI)

Terminated

CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer

Metastatic Cancer | Metastatic Melanoma | Renal Cancer

United States
National Cancer Institute (NCI)

Terminated

Modified White Blood Cells That Secrete IL-2 and Express a Protein That Targets the ESO-1tumor Protein for Metastatic Cancer

Metastatic Cancer | Metastatic Melanoma | Metastatic Renal Cancer

United States
National Cancer Institute (NCI)

Terminated

MAGE-A3/12 Metastatic Cancer Treatment With Anti-MAGE-A3/12 TCR-Gene Engineered Lymphocytes

Metastatic Cancer | Metastatic Melanoma | Metastatic Renal Cancer

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Computer-Based Survey and Communication Aid in Improving Physician-Patient Communication and Treatment Decision Making in Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
MediGene

Completed

A Trial Evaluating the Pharmacokinetics and Mode of Action of EndoTAG®-1 in Tumor Patients With Hepatic Metastases

Neoplasm Metastasis | Liver Cancer

Germany
SynerGene Therapeutics, Inc.

Completed

A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors (SGT94-01)

Neoplasm

United States
Seoul National University Hospital

Completed

Helicobacter Pylori Eradication After Endoscopic Resection of Gastric Tumors

Gastric Tumor | Helicobacter Pylori | Endoscopic Resection | Metachronous Neoplasms

Korea, Republic of
Acrotech Biopharma Inc.

Completed

Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder

Carcinoma, Transitional Cell | Bladder Cancer | Bladder Neoplasm

Spain, France, Belgium, United States, Argentina, Croatia
Bioniche Life Sciences Inc.

Terminated

Efficacy and Safety Evaluation of EN3348 (Mycobacterial Cell Wall-DNA Complex [MCC]) as Compared With Mitomycin C in the Intravesical Treatment of Subjects With BCG Recurrent/Refractory Non-muscle Invasive Bladder Cancer (EMBARC-RF)

Carcinoma in Situ | Neoplasm Recurrence, Local | Bladder Neoplasm | Mycobacterium | Transitional Cell, Carcinoma

United States, Canada, Poland, Germany, Netherlands, United Kingdom
GamaMabs Pharma

Completed

First In Human Safety, Pharmacokinetics and Anti-tumoral Activity of GM102 in Gynecological Cancers

Neoplasm, Gynecologic

France, Belgium, United Kingdom
Universita di Verona

Completed

Failure to Adjuvant Therapy After Pancreatic Resection for Pancreatic Cancer (FOUNTAIN)

Pancreatic Malignant Neoplasm Primary

Italy
Dartmouth-Hitchcock Medical Center

Withdrawn

Genetically-informed Therapies for Patients With Metastatic Cancer (GENIUS)

Metastatic Cancer

United States
Roshni Dasgupta

Recruiting

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Solid Malignancies | Metastatic Disease | Primary Tumor

United States
Regina Elena Cancer Institute

Completed

Goal Directed Therapy (GDT) in Cytoreductive Surgery (CRS) and Hyperthermic Intra Peritoneal Chemotherapy (Hipec)

Primary Peritoneal Neoplasm | Secondary Peritoneal Neoplasm

Italy
The Netherlands Cancer Institute
Bristol-Myers Squibb

Recruiting

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab (TURANDORELA)

Neoplasms | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Urinary Bladder Diseases | Male Urogenital Diseases | Female Urogenital Diseases | Urinary Bladder Neoplasm | Female Urogenital Diseases and Pregnancy Complications | Antineoplastics Toxicity | Urogenital Diseases

Netherlands
Vanderbilt University Medical Center
University of Alabama at Birmingham; Emory University; H. Lee Moffitt Cancer... and other collaborators

Terminated

Risk Factors for Adult-Onset Brain Tumors

Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Brain Neoplasm, Primary

United States
Niels Fristrup
Aarhus University Hospital

Recruiting

Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-Trial (NORDIC-SUN)

Kidney Cancer | Renal Cell Carcinoma Metastatic | Synchronous Neoplasm

Denmark
M.D. Anderson Cancer Center
Pharmacia; LifeCell

Completed

rhTPO Mobilized Auto Cryo Platelets For GYN Patients Receiving Carboplatin

Neoplasms, Gynecologic

United States
Assiut University

Unknown

Does Simethicone Improve Operative Field in Gynecological Operations

Benign Gynecologic Neoplasm

Egypt
Novartis Pharmaceuticals

Terminated

An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404

Metastatic Cancer With Impaired Renal Function | Metastatic Cancer With Normal Renal Function

Belgium
National Cancer Institute (NCI)

Completed

Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Malignant Solid Neoplasm | Recurrent Thyroid Gland Carcinoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Thyroid Gland Medullary Carcinoma

United States, Canada
University of Colorado, Denver

Completed

A Pilot Study to Enhance F18 FDG-PET Imaging of Prostate Cancers With the Metabolic Inhibitor Ranolazine

Bone Metastases | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer | Soft Tissue Metastases

United States
University of Tennessee
University of Tennessee West Cancer Center

Completed

Post-Operative Gynecological Oncology App Study (POGO)

Genital Neoplasm, Female

United States
OHSU Knight Cancer Institute
Astellas Pharma US, Inc.; Oregon Health and Science University

Active, not recruiting

Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy

Castration-Resistant Prostate Carcinoma | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Soft Tissues | Recurrent Prostate Carcinoma | Metastatic Prostate Adenocarcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage IV Prostate Adenocarcinoma AJCC v7

United States
The University of Hong Kong
Novartis

Recruiting

Asian Myeloproliferative Neoplasm (MPN) Registry

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Myeloproliferative Neoplasm | Post-polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis | Primary Myelofibrosis, Prefibrotic Stage | Primary Myelofibrosis, Fibrotic Stage

Hong Kong
St. Joseph's Healthcare Hamilton

Recruiting

Synapse 3D With Intravascular Indocyanine Green

Non-small Cell Lung Cancer | Primary Neoplasm

Canada
National Cancer Institute (NCI)

Completed

A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors

Brain Cancer | Brain Neoplasm | Brain Tumor, Primary

United States
Centre Leon Berard

Terminated

Efficacy of HIFU-AR on Blood Loss Reduction in Patients With Liver Metastases Requiring Hepatectomy (HIFU-AR)

Liver Metastasis

France
Sanofi

Completed

Pharmacokinetics and Safety Study of Cabazitaxel in Cancer Patients With Renal Impairment

Neoplasm Malignant

Netherlands, Belgium, Spain, Italy, United Kingdom
Samsung Medical Center

Completed

Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy

Abdominal Neoplasms | Gynecologic Neoplasms

Korea, Republic of
Peking Union Medical College Hospital

Completed

Lenvatinib Combined Pembrolizumab in Advanced Hepatobiliary Tumors

Cholangiocarcinoma | Biomarker | Combinational Immunotherapy | Liver Neoplasm Malignant Primary

China
Avenge Bio, Inc

Terminated

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer | Primary Peritoneal Carcinoma | Neoplasm, Ovarian | Adenocarcinoma Ovary | Serous Adenocarcinoma of Ovary | Serous Adenocarcinoma of Primary Peritoneum | High Grade Serous Adenocarcinoma

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Erlotinib in Treating Patients With Advanced Liver Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma

United States
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Patients With Liver Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma

United States
Samsung Medical Center

Active, not recruiting

An Open Label Phase II Study of Biweekly Docetaxel Plus Androgen-Deprivation Therapy in Patients With Previously-Untreated, Metastatic, Prostatic Adenocarcinoma

Prostatic Neoplasm

Korea, Republic of
The University of Texas Health Science Center at...

Completed

Impact of Exercise on Prognostic Biomarkers Related to Prostate Cancer

Prostatic Neoplasm

United States
Regina Elena Cancer Institute
Adriana Faiella; Paola Nisticò; Iole Cordone; Paola Trono; Serena Masi; Roberta Merola and other collaborators

Unknown

The Immunodynamic Effect of Radiotherapy in Prostate Cancer Patients.

Prostatic Neoplasm

Italy
Fondazione del Piemonte per l'Oncologia

Completed

Comparison of Multi-parametric and Bi-parametric Magnetic Resonance Imaging in Men With Suspicion of Prostate Cancer

Prostatic Neoplasm

Italy
Aurelius Omlin
University Hospital, Zürich; Teva Pharma

Terminated

Carboplatin in Castration-resistant Prostate Cancer (PRO-PLAT)

Prostatic Neoplasm

Switzerland
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

CT/MRI Co-registration Prostate Cancer

Prostatic Neoplasm

Canada
Schiffler Cancer Center

Completed

Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial

Prostatic Neoplasm

United States
Sanofi

Completed

Evaluation of SR 31747A Versus Placebo in Androgen-Independent Non Metastatic Prostate Cancer (ODYSSEY)

Prostatic Neoplasm

France, Canada, Poland, Italy, Netherlands, Portugal, Spain, Belgium, Czech Republic, Mexico, Australia, Chile, United Kingdom
National Cancer Institute (NCI)

Completed

A Randomized Phase II Study of Oral Thalidomide in Patients With Hormone-Refractory Prostate Cancer

Prostatic Neoplasm

United States
University of Campania "Luigi Vanvitelli"

Completed

Effects of Tissue Sealers on Minor Laparoscopic Procedures Between Obstetrics and Gynecology Residents

Benign Gynecologic Neoplasm

Italy

Clinical Trials on Primary Neoplasm

Sponsors and Collaborators

Medical Conditions

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CROs by country

CROs in Vietnam

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Rare Diseases

Drug Interventions

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